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Article ; Online: Left ventricular pseudoaneurysm

Juliana Sitta, MD / Candace M. Howard, MD, PhD

Radiology Case Reports, Vol 16, Iss 3, Pp 538-

An unexpected finding

2021 Volume 542

Abstract: A left ventricle pseudoaneurysm (LV PSA) is defined as a free wall rupture of the left ventricle contained by the adjacent pericardial tissue. This rare complication is most commonly encountered following myocardial infarction, trauma, or infection. ... ...

Abstract	A left ventricle pseudoaneurysm (LV PSA) is defined as a free wall rupture of the left ventricle contained by the adjacent pericardial tissue. This rare complication is most commonly encountered following myocardial infarction, trauma, or infection. Surgery is typically warranted to avoid progression to spontaneous rupture, which may potentially lead to cardiac tamponade and death. Cardiac magnetic resonance imaging is the modality of choice to characterize left ventricle morphology and function. Accurate distinction between a pseudoaneurysm and a true aneurysm is crucial, since management and prognosis are significantly different between these 2 entities. We present a case of a 63-year-old male heart transplant recipient, admitted for suspicion of acute cellular rejection, with an unexpected finding of a LV PSA.
Keywords	Left ventricle pseudoaneurysm ; Cardiac magnetic resonance ; Acute cellular rejection ; Heart transplant ; Myocardial infarction ; Left ventricular aneurysm ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Subject code	610
Language	English
Publishing date	2021-03-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Multifocal IgG4-related aortitis and periaortitis simulating aortic dissection

Amrita Valluri, BS / Juliana Sitta, MD / Candace M. Howard, MD, PhD

Radiology Case Reports, Vol 16, Iss 8, Pp 2274-

2021 Volume 2279

Abstract: Immunoglobulin G4-related aortitis (IgG4-RA) is histologically characterized by the infiltration of IgG4 positive plasma cells and fibrosis in systemic organs and the elevation of serum IgG4 levels. The cardiovascular system is commonly involved with ... ...

Abstract	Immunoglobulin G4-related aortitis (IgG4-RA) is histologically characterized by the infiltration of IgG4 positive plasma cells and fibrosis in systemic organs and the elevation of serum IgG4 levels. The cardiovascular system is commonly involved with various possible presentations such as aortitis, arteritis, periaortitis, periarteritis, and inflammatory aneurysm. We present a case of a 48-year-old male without known previous medical history, admitted for further workup of long-standing chest pain and shortness of breath with suspected aortic dissection on initial assessment. Investigation with computed tomography angiography (CTA) and magnetic resonance angiography (MRA) indicated severe thoracic and abdominal aortoarteritis associated with an ascending thoracic aortic aneurysm, which was confirmed to be IgG4-RA on histopathologic analysis. Thoracic and abdominal IgG4-RA clinical and radiological presentation may simulate other causes of acute aortic syndrome such as aortic dissection, atherosclerotic aneurysm and inflammatory conditions. Accurate recognition of IgG4-RA diagnostic imaging features are essential for early diagnosis and treatment surveillance.
Keywords	IgG4-related disease ; Aortitis ; Periaortitis ; CT angiography ; MR angiography ; Inflammatory aortic disease ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Subject code	610
Language	English
Publishing date	2021-08-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
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Article: Role of Gait Speed, Strength, and Balance in Predicting Adverse Outcomes of Acutely Ill Older Outpatients

Fortes-Filho, Sileno Queiroz / Aliberti, M. J. R / Apolinario, D / Melo-Fortes, J. A / Sitta, M. C / Jacob-Filho, W / Garcez-Leme, L. E

journal of nutrition, health & aging. 2020 Jan., v. 24, no. 1

2020

Abstract: AIM: To evaluate the ability of the Short Physical Performance Battery (SPPB) for predicting 1-year adverse outcomes of acutely ill older outpatients. METHODS: Prospective study with 512 acutely ill older outpatients (79.4±8.3 years, 63% female) in an ... ...

Abstract	AIM: To evaluate the ability of the Short Physical Performance Battery (SPPB) for predicting 1-year adverse outcomes of acutely ill older outpatients. METHODS: Prospective study with 512 acutely ill older outpatients (79.4±8.3 years, 63% female) in an acute care day hospital. The SPPB was administered at admission. Participants were classified as low (0–4 points), intermediate (5–8 points), or high (9–12 points) performance. Primary outcomes were new dependence in basic activities of daily living (ADL), hospitalization, and death at 1 year. Cox models tested whether the SPPB predicted outcomes after adjustment for sociodemographic factors, comorbidities and well-known geriatric conditions. We also estimated whether the chair-stand and balance tests improve the SPPB’s ability to identify patients at high risk of adverse outcomes. RESULTS: Patients with intermediate or low SPPB performance were at higher risk of 1-year new ADL dependence (32% vs 13%: adjusted hazard ratio [aHR]=2.00; 95%CI=1.18–3.37; 58% vs 13%: aHR=3.40; 95%CI=2.00–5.85, respectively), hospitalization (43% vs 29%: aHR=1.56; 95%CI=1.04–2.33; 44% vs 29%: aHR=1.80; 95%CI=1.15–2.82), and death (18% vs 6%: aHR=2.54; 95%CI=1.17–5.53; 21% vs 6%: aHR=2.70; 95%CI=1.17–6.21). Use of all three components (versus gait speed alone) improved predictions of new ADL dependence (Harrell’s C=0.73 vs 0.70;P=0.01), hospitalization (Harrell’s C=0.60 vs 0.57;P=0.04), and death (Harrell’s C=0.67 vs 0.62;P=0.04). CONCLUSIONS: The SPPB is as a powerful tool for identifying acutely ill older outpatients at high-risk of adverse outcomes. The combination of the three components of the SPPB resulted in better predictive performance than gait speed alone.
Keywords	adults at risk ; comorbidity ; death ; exercise test ; females ; gait ; hospitals ; patients ; prediction ; prospective studies ; sociodemographic characteristics
Language	English
Dates of publication	2020-01
Size	p. 113-118.
Publishing place	Springer Paris
Document type	Article
ZDB-ID	2081921-3
ISSN	1760-4788 ; 1279-7707
ISSN (online)	1760-4788
ISSN	1279-7707
DOI	10.1007/s12603-019-1279-6
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Role of Gait Speed, Strength, and Balance in Predicting Adverse Outcomes of Acutely Ill Older Outpatients.

Fortes-Filho, S Q / Aliberti, M J R / Apolinario, D / Melo-Fortes, J A / Sitta, M C / Jacob-Filho, W / Garcez-Leme, L E

The journal of nutrition, health & aging

2019 Volume 24, Issue 1, Page(s) 113–118

Abstract: Aim: To evaluate the ability of the Short Physical Performance Battery (SPPB) for predicting 1-year adverse outcomes of acutely ill older outpatients.: Methods: Prospective study with 512 acutely ill older outpatients (79.4±8.3 years, 63% female) in ... ...

Abstract	Aim: To evaluate the ability of the Short Physical Performance Battery (SPPB) for predicting 1-year adverse outcomes of acutely ill older outpatients. Methods: Prospective study with 512 acutely ill older outpatients (79.4±8.3 years, 63% female) in an acute care day hospital. The SPPB was administered at admission. Participants were classified as low (0-4 points), intermediate (5-8 points), or high (9-12 points) performance. Primary outcomes were new dependence in basic activities of daily living (ADL), hospitalization, and death at 1 year. Cox models tested whether the SPPB predicted outcomes after adjustment for sociodemographic factors, comorbidities and well-known geriatric conditions. We also estimated whether the chair-stand and balance tests improve the SPPB's ability to identify patients at high risk of adverse outcomes. Results: Patients with intermediate or low SPPB performance were at higher risk of 1-year new ADL dependence (32% vs 13%: adjusted hazard ratio [aHR]=2.00; 95%CI=1.18-3.37; 58% vs 13%: aHR=3.40; 95%CI=2.00-5.85, respectively), hospitalization (43% vs 29%: aHR=1.56; 95%CI=1.04-2.33; 44% vs 29%: aHR=1.80; 95%CI=1.15-2.82), and death (18% vs 6%: aHR=2.54; 95%CI=1.17-5.53; 21% vs 6%: aHR=2.70; 95%CI=1.17-6.21). Use of all three components (versus gait speed alone) improved predictions of new ADL dependence (Harrell's C=0.73 vs 0.70;P=0.01), hospitalization (Harrell's C=0.60 vs 0.57;P=0.04), and death (Harrell's C=0.67 vs 0.62;P=0.04). Conclusions: The SPPB is as a powerful tool for identifying acutely ill older outpatients at high-risk of adverse outcomes. The combination of the three components of the SPPB resulted in better predictive performance than gait speed alone.
MeSH term(s)	Activities of Daily Living ; Aged ; Aged, 80 and over ; Comorbidity ; Female ; Geriatric Assessment/methods ; Hospitalization ; Humans ; Male ; Muscle Strength/physiology ; Outpatients ; Physical Functional Performance ; Postural Balance/physiology ; Prognosis ; Proportional Hazards Models ; Prospective Studies ; Walking Speed/physiology
Language	English
Publishing date	2019-09-23
Publishing country	France
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2081921-3
ISSN	1760-4788 ; 1279-7707
ISSN (online)	1760-4788
ISSN	1279-7707
DOI	10.1007/s12603-019-1279-6
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Article ; Online: Heavy flavors in nucleus-nucleus collisions at RHIC and LHC

Nardi Marzia / Alberico W.M. / Molinari A. / Beraudo A. / De Pace A. / Monteno M. / Prino F. / Sitta M.

EPJ Web of Conferences, Vol 71, p

2014 Volume 00098

Abstract: A multi-step setup for heavy-flavor studies in high-energy nucleus-nucleus (AA) collisions — addressing within a comprehensive framework the initial QQ¯$Q\overline Q $ production, the propagation in the hot medium until decoupling and the final ... ...

Abstract	A multi-step setup for heavy-flavor studies in high-energy nucleus-nucleus (AA) collisions — addressing within a comprehensive framework the initial QQ¯$Q\overline Q $ production, the propagation in the hot medium until decoupling and the final hadronization and decays — is presented. The propagation of the heavy quarks in the medium is described in a framework provided by the relativistic Langevin equation and the corresponding numerical results are compared to experimental data from RHIC and the LHC. In particular, outcomes for the nuclear modification factor RAA and for the elliptic flow υ2 of D/B mesons, heavy-flavor electrons and non-prompt J/ψ’s are displayed.
Keywords	Physics ; QC1-999 ; Science ; Q
Language	English
Publishing date	2014-04-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Association between plasma testosterone level and bone mineral density in healthy elderly men.

Iucif, Nelson / Marchini, Julio S / do Carmo Sitta, Maria / Cunha, Selma F C / Bestetti, Reinaldo B / Suen, Vivian M M

Journal of the American Geriatrics Society

2014 Volume 62, Issue 5, Page(s) 981–982

MeSH term(s)	Absorptiometry, Photon ; Aged ; Biomarkers/blood ; Bone Density/physiology ; Brazil/epidemiology ; Humans ; Incidence ; Male ; Middle Aged ; Osteoporosis/blood ; Osteoporosis/diagnostic imaging ; Osteoporosis/epidemiology ; Reference Values ; Risk Factors ; Testosterone/blood
Chemical Substances	Biomarkers ; Testosterone (3XMK78S47O)
Language	English
Publishing date	2014-05
Publishing country	United States
Document type	Letter
ZDB-ID	80363-7
ISSN	1532-5415 ; 0002-8614
ISSN (online)	1532-5415
ISSN	0002-8614
DOI	10.1111/jgs.12807
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Article: Risk factors for prolapse development in white, black, and Hispanic women.

Kudish, Bela I / Iglesia, Cheryl B / Gutman, Robert E / Sokol, Andrew I / Rodgers, Allison K / Gass, Marjery / O'Sullivan, Mary Jo / Larson, Joseph / Abu-Sitta, Moeen / Howard, Barbara V

Female pelvic medicine & reconstructive surgery

2012 Volume 17, Issue 2, Page(s) 80–90

Abstract: Objectives: : This study aimed to examine the risk factors for prevalence and incidence of pelvic organ prolapse (POP) in whites, Hispanics, and blacks.: Methods: : This is a secondary analysis of the Women's Health Initiative (WHI) Estrogen plus ... ...

Abstract	Objectives: : This study aimed to examine the risk factors for prevalence and incidence of pelvic organ prolapse (POP) in whites, Hispanics, and blacks. Methods: : This is a secondary analysis of the Women's Health Initiative (WHI) Estrogen plus Progestin Clinical Trial (E + P). Of the original E + P trial population of 16,608, 12,667 women (78.3%; 11,194 whites, 804 blacks, and 669 Hispanics) were included in the final study sample and evaluated during the 5-year period. The outcomes evaluated were any prolapse (WHI prolapse grades 1-3) and WHI prolapse grade 2 or 3. Descriptive analyses, logistic regression, and proportional hazard modeling were performed. Results: : Increasing parity correlates with increasing WHI prolapse grades (0-3) in whites and blacks but not Hispanics. The incidence of grade 2 or 3 POP increased by 250% in white women with 1 child (hazard ratio [HR], 2.50; 95% confidence interval [CI], 1.68-3.71) in comparison to nulliparous women and grew with higher parity. For blacks, a weak association between the parity and grade 2 or 3 POP was noted only in women who had 5 or more kids (HR, 10.41; 95% CI, 1.38-78.77). Blacks were less likely (HR, 0.53; 95% CI, 0.40-0.71) to develop grade 2 or 3 POP compared with whites. For grade 2 or 3 POP, age was found to be a risk factor in whites (odds ratio [OR], 1.03; 95% CI, 1.02-1.04) only and body mass index (≥25 kg/m, <30 kg/m) in whites (OR, 1.64; 95% CI, 1.34-2.02) and Hispanics (OR, 2.87; 95% CI, 1.03-2.02). Conclusions: : White women are at a much greater risk for developing grade 2 or 3 POP compared with blacks. Parity correlates most strongly with the risk of prolapse development in whites and possibly in grand multiparous blacks.
Language	English
Publishing date	2012-03-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	2542707-6
ISSN	2154-4212 ; 2151-8378
ISSN (online)	2154-4212
ISSN	2151-8378
DOI	10.1097/SPV.0b013e31820e5d06
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Article: Contrast cancellation technique applied to digital x-ray imaging using silicon strip detectors.

Avila, C / Lopez, J / Sanabria, J C / Baldazzi, G / Bollini, D / Gombia, M / Cabal, A E / Ceballos, C / Diaz Garcia, A / Gambaccini, M / Taibi, A / Sarnelli, A / Tuffanelli, A / Giubellino, P / Marzari-Chiesa, A / Prino, F / Tomassi, E / Grybos, P / Idzik, M /

Swientek, K / Wiacek, P / Montaño, L M / Ramello, L / Sitta, M

Medical physics

2005 Volume 32, Issue 12, Page(s) 3755–3766

Abstract: Dual-energy mammographic imaging experimental tests have been performed using a compact dichromatic imaging system based on a conventional x-ray tube, a mosaic crystal, and a 384-strip silicon detector equipped with full-custom electronics with single ... ...

Abstract	Dual-energy mammographic imaging experimental tests have been performed using a compact dichromatic imaging system based on a conventional x-ray tube, a mosaic crystal, and a 384-strip silicon detector equipped with full-custom electronics with single photon counting capability. For simulating mammal tissue, a three-component phantom, made of Plexiglass, polyethylene, and water, has been used. Images have been collected with three different pairs of x-ray energies: 16-32 keV, 18-36 keV, and 20-40 keV. A Monte Carlo simulation of the experiment has also been carried out using the MCNP-4C transport code. The Alvarez-Macovski algorithm has been applied both to experimental and simulated data to remove the contrast between two of the phantom materials so as to enhance the visibility of the third one.
MeSH term(s)	Algorithms ; Biophysical Phenomena ; Biophysics ; Female ; Humans ; Mammography/methods ; Mammography/statistics & numerical data ; Monte Carlo Method ; Phantoms, Imaging/statistics & numerical data ; Radiographic Image Enhancement/methods ; Silicon
Chemical Substances	Silicon (Z4152N8IUI)
Language	English
Publishing date	2005-12
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	188780-4
ISSN	0094-2405
ISSN	0094-2405
DOI	10.1118/1.2126568
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Article: GPCALMA: a Grid-based tool for mammographic screening.

Cerello, P / Bagnasco, S / Bottigli, U / Cheran, S C / Delogu, P / Fantacci, M E / Fauci, F / Forni, G / Lauria, A / Lopez Torres, E / Magro, R / Masala, G L / Oliva, P / Palmiero, R / Ramello, L / Raso, G / Retico, A / Sitta, M / Stumbo, S /

Tangaro, S / Zanon, E

Methods of information in medicine

2005 Volume 44, Issue 2, Page(s) 244–248

Abstract: Objectives: The next generation of high energy physics (HEP) experiments requires a GRID approach to a distributed computing system: the key concept is the Virtual ORGANISATION (VO), a group of distributed users with a common goal and the will to share ... ...

Abstract	Objectives: The next generation of high energy physics (HEP) experiments requires a GRID approach to a distributed computing system: the key concept is the Virtual ORGANISATION (VO), a group of distributed users with a common goal and the will to share their resources. Methods: A similar approach, applied to a group of hospitals that joined the GPCALMA project (Grid Platform for Computer Assisted Library for MAmmography), will allow common screening programs for early diagnosis of breast and, in the future, lung cancer. The application code makes use of neural networks for the image analysis and is useful in improving the radiologists' diagnostic performance. GRID services allow remote image analysis and interactive online diagnosis, with a potential for a relevant reduction of the delays presently associated with screening programs. Results and conclusions: A prototype of the system, based on AliEn GRID Services [1], is already available, with a central server running common services [2] and several clients connecting to it. Mammograms can be acquired in any location; the related information required to select and access them at any time is stored in a common service called Data Catalogue, which can be queried by any client. Thanks to the PROOF facility [3], the result of a query can be used as input for analysis algorithms, which are executed on the nodes where the input images are stored,. The selected approach avoids data transfers for all the images with a negative diagnosis and allows an almost real time diagnosis for the set of images with high cancer probability.
MeSH term(s)	Algorithms ; Breast Neoplasms/diagnostic imaging ; Database Management Systems ; Databases, Factual ; Diagnosis, Computer-Assisted ; Europe ; Female ; Humans ; Internationality ; Internet/instrumentation ; Italy ; Mammography ; Medical Records Systems, Computerized ; Program Development ; Radiology Information Systems/instrumentation ; Systems Integration ; Teleradiology/instrumentation ; User-Computer Interface
Language	English
Publishing date	2005
Publishing country	Germany
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	3500-2
ISSN	0026-1270
ISSN	0026-1270
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: GPCALMA: a Grid-based Tool for Mammographic Screening

Cerello, P. / Bagnasco, S. / Bottigli, U. / Cheran, S. C. / Delogu, P. / Fantacci, M. E. / Fauci, F. / Forni, G. / Lauria, A. / Lopez Torres, E. / Magro, R. / Masala, G. L. / Oliva, P. / Palmiero, R. / Ramello, L. / Raso, G. / Retico, A. / Sitta, M. / Stumbo, S. /

Tangaro, S. / Zanon, E.

Methods of Information in Medicine

2005 Volume 44, Issue 02, Page(s) 244–248

Abstract: Objectives: The next generation of high energy physics (HEP) experiments requires a GRID approach to a distributed computing system: the key concept is the Virtual Organisation (VO), a group of distributed users with a common goal and the will to share ...

Abstract	Objectives: The next generation of high energy physics (HEP) experiments requires a GRID approach to a distributed computing system: the key concept is the Virtual Organisation (VO), a group of distributed users with a common goal and the will to share their resources. Methods: A similar approach, applied to a group of hospitals that joined the GPCALMA project (Grid Platform for Computer Assisted Library for MAmmography), will allow common screening programs for early diagnosis of breast and, in the future, lung cancer. The application code makes use of neural networks for the image analysis and is useful in improving the radiologists' diagnostic performance. GRID services allow remote image analysis and interactive online diagnosis, with a potential for a relevant reduction of the delays presently associated with screening programs. Results and Conclusions: A prototype of the system, based on AliEn GRID Services [1], is already available, with a central server running common services [2] and several clients connecting to it. Mammograms can be acquired in any location; the related informatio required to select and access them at any time is stored in a common service called Data Catalogue, which can be queried by any client. Thanks to the PROOF facility [3], the result of a query can be used as input for analy-sis algorithms, which are executed on the nodes where the input images are stored,. The selected approach avoids data transfers for all the images with a negative diagnosis and allows an almost real time diagnosis for the set of images with high cancer probability.
Keywords	Grid ; mammogram ; screening ; virtual organization
Language	English
Publishing date	2005-02-01
Publisher	Schattauer GmbH
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	3500-2
ISSN	2511-705X ; 0026-1270
ISSN (online)	2511-705X
ISSN	0026-1270
DOI	10.1055/s-0038-1633955
Database	Thieme publisher's database

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