Article ; Online: An interesting case of 'diabetic foot ulcer' in an HIV-positive patient.
International journal of STD & AIDS
2015 Volume 26, Issue 4, Page(s) 285–287
Abstract: Kaposi sarcoma is a highly vascularised tumour affecting the skin, lymph nodes and viscera. Kaposi sarcoma is most common in HIV-infected homosexual or bisexual men. We present here a 70-year-old white British male patient, who was under the care of the ... ...
| Abstract | Kaposi sarcoma is a highly vascularised tumour affecting the skin, lymph nodes and viscera. Kaposi sarcoma is most common in HIV-infected homosexual or bisexual men. We present here a 70-year-old white British male patient, who was under the care of the podiatric team for longstanding 'diabetic foot ulcers'. He was later referred to the Dermatology team who took a biopsy; this revealed features of Kaposi sarcoma which prompted an HIV test which was positive. This patient had previously presented to several healthcare professionals with symptoms suggestive of HIV infection. He was started on antiretroviral therapy and the HIV and human herpesvirus-8 viral loads became undetectable in the blood within weeks and he showed significant clinical improvement. This case report is a reminder to clinicians to have a high index of suspicion in patients presenting with symptoms and signs suggestive of HIV infection. |
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| MeSH term(s) | Adenine/analogs & derivatives ; Adenine/therapeutic use ; Aged ; Antiretroviral Therapy, Highly Active ; Biopsy ; Deoxycytidine/analogs & derivatives ; Deoxycytidine/therapeutic use ; Diabetes Mellitus, Type 2/complications ; Diabetic Foot/complications ; Diabetic Foot/drug therapy ; Emtricitabine ; HIV Infections/complications ; HIV Infections/drug therapy ; HIV Seropositivity/complications ; HIV Seropositivity/drug therapy ; HIV Seropositivity/pathology ; HIV Seropositivity/virology ; Herpesvirus 8, Human/drug effects ; Herpesvirus 8, Human/isolation & purification ; Humans ; Male ; Organophosphonates/therapeutic use ; Sarcoma, Kaposi/diagnosis ; Sarcoma, Kaposi/drug therapy ; Skin Neoplasms/drug therapy ; Skin Neoplasms/pathology ; Skin Neoplasms/virology ; Tenofovir ; Treatment Outcome ; Ulcer/etiology |
| Chemical Substances | Organophosphonates ; Deoxycytidine (0W860991D6) ; Tenofovir (99YXE507IL) ; Emtricitabine (G70B4ETF4S) ; Adenine (JAC85A2161) |
| Language | English |
| Publishing date | 2015-03 |
| Publishing country | England |
| Document type | Case Reports ; Journal Article |
| ZDB-ID | 1018089-8 |
| ISSN | 1758-1052 ; 0956-4624 |
| ISSN (online) | 1758-1052 |
| ISSN | 0956-4624 |
| DOI | 10.1177/0956462414534826 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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