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  1. Book ; Conference proceedings: Immunomodulation - a new possibility in prevention of health

    Siwicki, Andrzej Krzysztof

    [Warsaw, December 2 - 3, 2004]

    (Polish journal of food and nutrition sciences ; 13, SI 2 = 54, SI 2)

    2004  

    Event/congress Scientific Conference Immunomodulation - a New Possibility in Protection of Human and Animal Health (2, 2004, Warschau)
    Author's details [II Scientific Conference Immunomodulation - a New Possibility in Protection of Human and Animal Health]. Guest scientific ed.: Andrzej Krzysztof Siwicki
    Series title Polish journal of food and nutrition sciences ; 13, SI 2 = 54, SI 2
    Collection
    Language English
    Size 87 S. : graph. Darst.
    Publisher Div. of Food Science, Inst. of Animal Reproduction and Food Research of Polish Acad. of Sciences
    Publishing place Olsztyn
    Publishing country Poland
    Document type Book ; Conference proceedings
    HBZ-ID HT014246291
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    Z 4427 (13,SI2) available for loan (reading room) Freihandmagazin (U1)

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  2. Article: In Vivo Bacteriophages' Application for the Prevention and Therapy of Aquaculture Animals-Chosen Aspects.

    Schulz, Patrycja / Pajdak-Czaus, Joanna / Siwicki, Andrzej Krzysztof

    Animals : an open access journal from MDPI

    2022  Volume 12, Issue 10

    Abstract: To meet the nutritional requirements of our growing population, animal production must double by 2050, and due to the exhaustion of environmental capacity, any growth will have to come from aquaculture. Aquaculture is currently undergoing a dynamic ... ...

    Abstract To meet the nutritional requirements of our growing population, animal production must double by 2050, and due to the exhaustion of environmental capacity, any growth will have to come from aquaculture. Aquaculture is currently undergoing a dynamic development, but the intensification of production increases the risk of bacterial diseases. In recent years, there has been a drastic development in the resistance of pathogenic bacteria to antibiotics and chemotherapeutic agents approved for use, which has also taken place in aquaculture. Consequently, animal mortality and economic losses in livestock have increased. The use of drugs in closed systems is an additional challenge as it can damage biological filters. For this reason, there has been a growing interest in natural methods of combating pathogens. One of the methods is the use of bacteriophages both for prophylactic purposes and therapy. This work summarizes the diverse results of the in vivo application of bacteriophages for the prevention and control of bacterial pathogens in aquatic animals to provide a reference for further research on bacteriophages in aquaculture and to compare major achievements in the field.
    Language English
    Publishing date 2022-05-10
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani12101233
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Genotoxicity and mutagenicity of molybdenum(III) and iron(III) and interactions between these microelements

    Terpilowska, Sylwia / Siwicki, Andrzej Krzysztof

    Trace elements and electrolytes

    2020  Volume 37, Issue 4, Page(s) 180

    Language German
    Document type Article
    ZDB-ID 1181166-3
    ISSN 0946-2104
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

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  4. Article ; Online: Pro- and antioxidant activity of chromium(III), iron(III), molybdenum(III) or nickel(II) and their mixtures.

    Terpilowska, Sylwia / Siwicki, Andrzej Krzysztof

    Chemico-biological interactions

    2018  Volume 298, Page(s) 43–51

    Abstract: The aim of this study was to examine the effect of chromium(III), iron(III), molybdenum(III) and nickel(II) and their combinations on pro- and antioxidant activity in mouse embryo fibroblasts and liver cancer cells. The present study shows that chromium( ... ...

    Abstract The aim of this study was to examine the effect of chromium(III), iron(III), molybdenum(III) and nickel(II) and their combinations on pro- and antioxidant activity in mouse embryo fibroblasts and liver cancer cells. The present study shows that chromium(III), iron(III), nickel(II) and molybdenum(III) induce oxidative stress. In the case of chromium(III), nickel(II) and molybdenum(III) the intracellular ROS were dominant. However, in the case of iron(III) MDA was dominant - the end product of lipid peroxidation. Antioxidant activity of superoxide dismutase and catalase increased in low concentration of chromium(III); however, they decreased in higher concentrations. The same enzymes decreased after iron(III), nickel(II) and molybdenum(III) treatment in dose dependent manner. The activity of glutathione peroxidise decreased in dose dependent manner in all used microelements. Additions of Cr(III) at 200 μM plus Fe(III) at 1000 μM showed synergistic effect in ROS production and in lowering antioxidant activity. The same type of interaction in pairs Cr(III) at 1000 μM plus Fe(III) or Ni(II) or Mo(III) at concentration of 200 μM was observed. The protective effects of Cr(III) in antioxidant activity and in lowering intracellular ROS production in pairs of Cr(III) at 200 μM and Ni(II) or Mo(III) at concentration of 1000 μM were observed.
    MeSH term(s) Animals ; Antioxidants/metabolism ; Antioxidants/pharmacology ; Cell Line ; Chromium/pharmacology ; Enzymes/metabolism ; Fibroblasts/drug effects ; Hep G2 Cells ; Humans ; Iron/pharmacology ; Mice ; Molybdenum/pharmacology ; Nickel/pharmacology ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism
    Chemical Substances Antioxidants ; Enzymes ; Reactive Oxygen Species ; Chromium (0R0008Q3JB) ; Nickel (7OV03QG267) ; Molybdenum (81AH48963U) ; Iron (E1UOL152H7)
    Language English
    Publishing date 2018-10-30
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 218799-1
    ISSN 1872-7786 ; 0009-2797
    ISSN (online) 1872-7786
    ISSN 0009-2797
    DOI 10.1016/j.cbi.2018.10.028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 686: Show issues Location:
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  5. Article ; Online: Interactions between chromium(III) and iron(III), molybdenum(III) or nickel(II): Cytotoxicity, genotoxicity and mutagenicity studies.

    Terpilowska, Sylwia / Siwicki, Andrzej Krzysztof

    Chemosphere

    2018  Volume 201, Page(s) 780–789

    Abstract: The aim of this study was to examine the effect of chromium(III) and iron(III) and molybdenum(III) and nickel(II) and their combinations on cyto-, genotoxicity and mutagenicity in BALB/3T3 and HepG2 cells. The results obtained from cytotoxicity assays ... ...

    Abstract The aim of this study was to examine the effect of chromium(III) and iron(III) and molybdenum(III) and nickel(II) and their combinations on cyto-, genotoxicity and mutagenicity in BALB/3T3 and HepG2 cells. The results obtained from cytotoxicity assays indicate that there are differences between BALB/3T3 and HepG2 cell lines in their sensitivity to chromium chloride, iron chloride, molybdenum trioxide and nickel chloride. The statistically significant increase of DNA damage of all used microelements in both cell lines was observed. The micronucleus assay performed with the use of all concentrations shows statistically significant induction of chromosomal aberrations in all tested microelements in both cell lines. Moreover, treated cells display characteristic apoptosis in comparison to control cells. In all tested microelements, the increase of number of reverse mutations was observed with and without metabolic activation. Additions of Cr(III) at 200 μM plus Fe(III) at 1000 μM showed synergistic effect in decrease of cell viability and increase of comets, micronuclei and number of revertants in both cell lines. In case of Cr(III) at 200 μM plus Mo(III) at 1000 μM, a protective effect of chromium against molybdenum at 1000 μM toxicity in both cell lines (assessed by MTT, LDH and NRU, comet, micronucleus and Ames assays) was observed. The protective effect of Cr(III) in decrease of cell viability was observed in pair of Cr(III) at 200 μM and Ni(II) at 1000 μM in BALB/3T3 and HepG2 cell lines assessed by MTT, LDH and NRU, comet, micronucleus and Ames assays.
    MeSH term(s) Animals ; BALB 3T3 Cells ; Cell Survival/drug effects ; Chlorides/toxicity ; Chromium Compounds/toxicity ; DNA Damage ; Dose-Response Relationship, Drug ; Drug Interactions ; Ferric Compounds/toxicity ; Hep G2 Cells ; Humans ; Mice ; Micronuclei, Chromosome-Defective/chemically induced ; Molybdenum/toxicity ; Nickel/toxicity ; Oxides/toxicity ; Salmonella typhimurium/drug effects
    Chemical Substances Chlorides ; Chromium Compounds ; Ferric Compounds ; Oxides ; molybdenum trioxide (22FQ3F03YS) ; nickel chloride (696BNE976J) ; Nickel (7OV03QG267) ; Molybdenum (81AH48963U) ; chromic chloride (KB1PCR9DMW) ; ferric chloride (U38V3ZVV3V)
    Language English
    Publishing date 2018-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2018.03.062
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2540: Show issues Location:
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  6. Article: Staphylococcus aureus

    Kaczorek-Łukowska, Edyta / Małaczewska, Joanna / Sowińska, Patrycja / Szymańska, Marta / Wójcik, Ewelina Agnieszka / Siwicki, Andrzej Krzysztof

    Pathogens (Basel, Switzerland)

    2022  Volume 11, Issue 12

    Abstract: Bovine mastitis is a common disease worldwide, and staphylococci are one of the most important etiological factors of this disease. ...

    Abstract Bovine mastitis is a common disease worldwide, and staphylococci are one of the most important etiological factors of this disease.
    Language English
    Publishing date 2022-11-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens11121404
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  7. Article ; Online: Cytotoxicity of iron (III), molybdenum (III), and their mixtures in BALB/3T3 and HepG2 cells

    Terpiłowska Sylwia / Siwicka-Gieroba Dorota / Siwicki Andrzej Krzysztof

    Journal of Veterinary Research, Vol 62, Iss 4, Pp 527-

    2018  Volume 533

    Abstract: Introduction: Iron and molybdenum are essential trace elements for cell metabolism. They are involved in maintaining proper functions of enzymes, cell proliferation, and metabolism of DNA. ...

    Abstract Introduction: Iron and molybdenum are essential trace elements for cell metabolism. They are involved in maintaining proper functions of enzymes, cell proliferation, and metabolism of DNA.
    Keywords molybdenum (iii) ; iron (iii) ; cytotoxicity ; interactions ; Veterinary medicine ; SF600-1100
    Language English
    Publishing date 2018-12-01T00:00:00Z
    Publisher Sciendo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Cell viability in normal fibroblasts and liver cancer cells after treatment with iron (III), nickel (II), and their mixture

    Terpiłowska Sylwia / Siwicka-Gieroba Dorota / Siwicki Andrzej Krzysztof

    Journal of Veterinary Research, Vol 62, Iss 4, Pp 535-

    2018  Volume 542

    Abstract: Introduction: Nickel and iron are very commonly occurring metals. Nickel is used in industry, but nowadays it is also used in medical biomaterials. Iron is an element necessary for cell metabolism and is used in diet supplements and biomaterials, whence ... ...

    Abstract Introduction: Nickel and iron are very commonly occurring metals. Nickel is used in industry, but nowadays it is also used in medical biomaterials. Iron is an element necessary for cell metabolism and is used in diet supplements and biomaterials, whence it may be released along with nickel.
    Keywords nickel (ii) ; iron (iii) ; cytotoxicity ; interactions ; Veterinary medicine ; SF600-1100
    Language English
    Publishing date 2018-12-01T00:00:00Z
    Publisher Sciendo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Chromium(III) and iron(III) inhibits replication of DNA and RNA viruses.

    Terpiłowska, Sylwia / Siwicki, Andrzej Krzysztof

    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine

    2017  Volume 30, Issue 4, Page(s) 565–574

    Abstract: The aim of this study was to examine the effect of treating of chromium(III) and iron(III) and their combinations on Herpes Simplex Virus type 1 (HSV-1) and Bovine Viral Diarrhoea virus (BVDV) replication. The antiviral efficacies of chromium(III) and ... ...

    Abstract The aim of this study was to examine the effect of treating of chromium(III) and iron(III) and their combinations on Herpes Simplex Virus type 1 (HSV-1) and Bovine Viral Diarrhoea virus (BVDV) replication. The antiviral efficacies of chromium(III) and iron(III) on HSV-1 and BVDV were evaluated using Real Time PCR method. Moreover, the cytotoxicity of these microelements was examined using the MTT reduction assay. The IC
    MeSH term(s) Animals ; Antiviral Agents/pharmacology ; Cattle ; Cell Line ; Cell Line, Tumor ; Chlorides/pharmacology ; Chromium Compounds/pharmacology ; DNA, Viral/antagonists & inhibitors ; DNA, Viral/biosynthesis ; Diarrhea Virus 1, Bovine Viral/drug effects ; Diarrhea Virus 1, Bovine Viral/genetics ; Diarrhea Virus 1, Bovine Viral/growth & development ; Dose-Response Relationship, Drug ; Drug Synergism ; Epithelial Cells/drug effects ; Epithelial Cells/virology ; Ferric Compounds/pharmacology ; Herpesvirus 1, Human/drug effects ; Herpesvirus 1, Human/genetics ; Herpesvirus 1, Human/growth & development ; Humans ; RNA, Viral/antagonists & inhibitors ; RNA, Viral/biosynthesis ; Virus Replication/drug effects
    Chemical Substances Antiviral Agents ; Chlorides ; Chromium Compounds ; DNA, Viral ; Ferric Compounds ; RNA, Viral ; chromous chloride (CET32HKA21) ; ferric chloride (U38V3ZVV3V)
    Language English
    Publishing date 2017-06-13
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1112688-7
    ISSN 1572-8773 ; 0966-0844
    ISSN (online) 1572-8773
    ISSN 0966-0844
    DOI 10.1007/s10534-017-0027-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2515: Show issues Location:
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  10. Article ; Online: No indication for SARS-CoV-2 transmission to pet ferrets, in five cities in Poland, 2021 - antibody testing among ferrets living with owners infected with SARS-CoV-2 or free of infection.

    Kaczorek-Łukowska, Edyta / Wernike, Kerstin / Beer, Martin / Blank, Alicja / Małaczewska, Joanna / Blank, Mirosława / Jałonicka, Anna / Siwicki, Andrzej Krzysztof

    Acta veterinaria Scandinavica

    2023  Volume 65, Issue 1, Page(s) 9

    Abstract: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first identified in China by the end of 2019 and was responsible for a pandemic in the human population that resulted in millions of deaths worldwide. Since the beginning of the ... ...

    Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first identified in China by the end of 2019 and was responsible for a pandemic in the human population that resulted in millions of deaths worldwide. Since the beginning of the pandemic, the role of animals as spill-over or reservoir hosts was discussed. In addition to cats and dogs, ferrets are becoming increasingly popular as companion animals. Under experimental conditions, ferrets are susceptible to SARS-CoV-2 and it appears that they can also be infected through contact with a SARS-CoV-2 positive owner. However, there is still little information available regarding these natural infections. Here, we serologically tested samples collected from pet ferrets (n = 45) from Poland between June and September 2021. Of the ferrets that were included in the study, 29% (13/45) had contact with owners with confirmed SARS-CoV-2 infections. Nevertheless, SARS-CoV-2-specific antibodies could not be detected in any of the animals, independent of the infection status of the owner. The obtained results suggest that ferrets cannot be readily infected with SARS-CoV-2 under natural conditions, even after prolonged contact with infected humans. However, due to the rapid mutation rate of this virus, it is important to include ferrets in future monitoring studies.
    MeSH term(s) Humans ; Animals ; Cats ; Dogs ; SARS-CoV-2 ; Poland/epidemiology ; COVID-19/veterinary ; Cities ; Ferrets ; Antibodies, Viral ; COVID-19 Testing/veterinary ; Cat Diseases ; Dog Diseases
    Chemical Substances Antibodies, Viral
    Language English
    Publishing date 2023-02-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 40137-7
    ISSN 1751-0147 ; 0044-605X
    ISSN (online) 1751-0147
    ISSN 0044-605X
    DOI 10.1186/s13028-023-00672-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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