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  1. Article ; Online: The needs of children born preterm are too often overlooked.

    Kennedy, Eilis / Skinner, Guy

    Lancet (London, England)

    2023  Volume 401, Issue 10383, Page(s) 1156

    MeSH term(s) Infant, Newborn ; Pregnancy ; Female ; Child ; Humans ; Infant, Premature ; Premature Birth/epidemiology ; Parturition
    Language English
    Publishing date 2023-03-29
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(23)00277-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The healthcare plight of offenders in the community.

    Skinner, Guy C M / Farrington, David P

    Criminal behaviour and mental health : CBMH

    2022  Volume 32, Issue 4, Page(s) 249–254

    MeSH term(s) Crime ; Criminals ; Delivery of Health Care ; Humans ; Sex Offenses
    Language English
    Publishing date 2022-08-28
    Publishing country England
    Document type Editorial
    ZDB-ID 2042697-5
    ISSN 1471-2857 ; 0957-9664
    ISSN (online) 1471-2857
    ISSN 0957-9664
    DOI 10.1002/cbm.2258
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The cost-of-living crisis, poverty, and child maltreatment.

    Skinner, Guy / Bywaters, Paul / Kennedy, Eilis

    The Lancet. Child & adolescent health

    2022  Volume 7, Issue 1, Page(s) 5–6

    MeSH term(s) Child ; Humans ; Poverty ; Child Abuse
    Language English
    Publishing date 2022-09-22
    Publishing country England
    Document type Journal Article
    ISSN 2352-4650
    ISSN (online) 2352-4650
    DOI 10.1016/S2352-4642(22)00252-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Health of Convicted Persons in the Third Generation of the Longitudinal Cambridge Study in Delinquent Development.

    Skinner, Guy C M / Farrington, David P

    International journal of offender therapy and comparative criminology

    2021  Volume 67, Issue 8, Page(s) 757–782

    Abstract: Research suggests that convicted persons are more likely than non-convicted persons to suffer poor health. However, few longitudinal studies have investigated associations between health and offending across generations. Using the Cambridge Study in ... ...

    Abstract Research suggests that convicted persons are more likely than non-convicted persons to suffer poor health. However, few longitudinal studies have investigated associations between health and offending across generations. Using the Cambridge Study in Delinquent Development, this article prospectively investigates the relationship between health and offending across generations and between genders. At the average age of 25, third generation convicted males and females reported a higher incidence of serious drug use than non-convicted persons. Convicted males reported a higher incidence of mental illness and self-harm, whereas convicted females reported a lower incidence of physical illness, mental illness, self-harm and hospitalizations when compared to non-convicted females. Convicted males reported a higher incidence of industrial accidents, sports injuries and fight injuries, but a lower incidence of road accidents, whereas convicted females were more likely to report road accidents. Like their fathers, convicted males show worse health compared to non-convicted individuals.
    MeSH term(s) Humans ; Male ; Female ; Adult ; Risk Factors ; Longitudinal Studies ; Hospitalization ; Incidence ; Antisocial Personality Disorder/epidemiology
    Language English
    Publishing date 2021-12-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 218274-9
    ISSN 1552-6933 ; 0306-624X
    ISSN (online) 1552-6933
    ISSN 0306-624X
    DOI 10.1177/0306624X211066837
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Self-reported and general practitioner recorded indicators of lifetime health up to age 48 according to offender type in the Cambridge Study in Delinquent Development.

    Skinner, Guy C M / Farrington, David P

    Criminal behaviour and mental health : CBMH

    2021  Volume 31, Issue 3, Page(s) 211–219

    Abstract: Background: Previous research has suggested that people with a history of offending have worse health compared to non-offenders, but it is less clear whether all types of offenders are at similar health risks. In a New Zealand birth cohort study, ... ...

    Abstract Background: Previous research has suggested that people with a history of offending have worse health compared to non-offenders, but it is less clear whether all types of offenders are at similar health risks. In a New Zealand birth cohort study, Moffitt evidenced three main offending trajectories-life-course-persistent (LCP), adolescence-limited (AL) and late-onset (LO) offending, subsequently confirmed in other substantial longitudinal studies.
    Aims: Our aim was to explore the relationship between these offending trajectories and both self-reported (SR) and general practitioner (GP) (primary care) recorded health indicators.
    Methods: Self-reported medical data at age 48 were obtained for 394 men followed since age 8 years in the Cambridge Study in Delinquent Development. In addition, medical records were obtained from GPs for 264 of them. Health indicators from both sources were compared between each of the three established trajectories of offenders across the life course-LCP, AL, LO and the non-offenders.
    Results: LCP offenders were found to have over twice the likelihood of disabling medical conditions according to both self-report and GP records. They were also more likely to have GP records indicating mental health problems and treatment for them. According to GP records alone, the LO offenders were also more likely to have mental health problems. The health of AL offenders appeared to be no different from that of the crime-free controls.
    Conclusions: Our findings add weight to the growing evidence that LCP offending and offending that only occurs relatively late in life are likely to be the indicators of generally unhealthy and disrupted lives. This suggests that if lifestyle is to change for the better, interventions are likely to be needed for health as well as antisocial behaviour.
    MeSH term(s) Adolescent ; Child ; Cohort Studies ; Criminals ; General Practitioners ; Humans ; Male ; Middle Aged ; New Zealand/epidemiology ; Self Report
    Language English
    Publishing date 2021-05-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2042697-5
    ISSN 1471-2857 ; 0957-9664
    ISSN (online) 1471-2857
    ISSN 0957-9664
    DOI 10.1002/cbm.2194
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Offender trajectories, health and hospital admissions: relationships and risk factors in the longitudinal Cambridge Study in Delinquent Development.

    Skinner, Guy Cm / Farrington, David P / Shepherd, Jonathan P

    Journal of the Royal Society of Medicine

    2020  Volume 113, Issue 3, Page(s) 110–118

    Abstract: Objectives: Research suggests that antisocial lifestyles constitute significant health risks. However, there are marked individual differences in the stability of antisocial behaviour. These different offending pathways may bear differential risks for ... ...

    Abstract Objectives: Research suggests that antisocial lifestyles constitute significant health risks. However, there are marked individual differences in the stability of antisocial behaviour. These different offending pathways may bear differential risks for adult health.
    Design: Injury and illness data were collected prospectively in the longitudinal Cambridge Study in Delinquent Development.
    Setting: Working-class inner-city area of South London.
    Participants: Participants included the 411 men from the Cambridge Study in Delinquent Development, with interview data collected at ages 18, 32 and 48 years for each individual.
    Main outcome measures: Organic illness, hospitalisation and injuries.
    Results: By age 48, adjusted odds ratios showed that the incidence of organic illness was higher among Life-Course-Persistent, Late-Onset offenders and offenders in general. Based on adjusted odds ratios at age 32, the incidence of hospitalisations was higher for Late-Onset offenders. Adjusted odds ratios at age 48 also showed that the incidence of hospitalisations was higher for all three offender types and offenders in general. Our results also provide evidence that offenders were more likely to suffer injuries than non-offenders.
    Conclusions: The findings of this study imply that preventing individuals from offending is likely to have substantial benefits for health.
    MeSH term(s) Adolescent ; Adult ; Antisocial Personality Disorder/epidemiology ; Child ; Crime/statistics & numerical data ; Criminals/statistics & numerical data ; Female ; Follow-Up Studies ; Humans ; Incidence ; Life Style ; London/epidemiology ; Male ; Mental Health ; Middle Aged ; Patient Admission/trends ; Prospective Studies ; Risk Assessment ; Risk Factors ; Social Environment ; Young Adult
    Language English
    Publishing date 2020-03-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 6731-3
    ISSN 1758-1095 ; 0141-0768 ; 0035-9157
    ISSN (online) 1758-1095
    ISSN 0141-0768 ; 0035-9157
    DOI 10.1177/0141076820905319
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: PROTOCOL: The effectiveness, implementation and cost effectiveness of mentoring programmes in reducing anti-social, violent and offending behaviour in children aged 17 years and below: A mixed method systematic review.

    Lakshminarayanan, Monisha / Skinner, Guy / Li, Jing / Tolan, Patrick / Du Bois, David / White, Howard

    Campbell systematic reviews

    2022  Volume 18, Issue 4, Page(s) e1286

    Abstract: This is the protocol for a Campbell systematic review. The review will address the following research questions: What is the evidence on the effects of adult mentoring programmes in reducing anti-social, violent and offending behaviour in children aged ... ...

    Abstract This is the protocol for a Campbell systematic review. The review will address the following research questions: What is the evidence on the effects of adult mentoring programmes in reducing anti-social, violent and offending behaviour in children aged under 18 years? Are these effects sustained after the end of mentoring? Which aspects/features of adult mentoring programmes promote the reduction of anti-social, violent and criminal behaviour in children aged under 18 years? What are the hindering factors/barriers that affect the successful implementation of adult mentoring programmes in children aged under 18 years? What are the supporting factors/facilitators that contribute to the successful implementation of adult mentoring programmes in children aged under 18 years? What is the evidence on programme costs and incremental cost effectiveness? (The incremental (or marginal cost) is the cost of providing the intervention over and above the cost of usual services).
    Language English
    Publishing date 2022-11-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2762761-5
    ISSN 1891-1803 ; 1891-1803
    ISSN (online) 1891-1803
    ISSN 1891-1803
    DOI 10.1002/cl2.1286
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Rapid detection and quantitation of dipicolinic acid from Clostridium botulinum spores using mixed-mode liquid chromatography-tandem mass spectrometry

    Redan, Benjamin W. / Morrissey, Travis R. / Rolfe, Catherine A. / Aguilar, Viviana L. / Skinner, Guy E. / Reddy, N. Rukma

    Analytical and bioanalytical chemistry. 2022 Mar., v. 414, no. 8

    2022  

    Abstract: Analysis of the dipicolinic acid (DPA) released from Clostridium botulinum spores during thermal processing is crucial to obtaining a mechanistic understanding of the factors involved in spore heat resistance and related food safety applications. Here, ... ...

    Abstract Analysis of the dipicolinic acid (DPA) released from Clostridium botulinum spores during thermal processing is crucial to obtaining a mechanistic understanding of the factors involved in spore heat resistance and related food safety applications. Here, we developed a novel mixed-mode liquid chromatography-tandem mass spectrometry (LC–MS/MS) method for detection of the DPA released from C. botulinum type A, nonproteolytic types B and F strains, and nonpathogenic surrogate Clostridium sporogenes PA3679 spores. DPA was retained on a mixed-mode C18/anion exchange column and was detected using electrospray ionization (ESI) positive mode within a 4-min analysis time. The intraday and interday precision (%CV) was 1.94–3.46% and 4.04–8.28%, respectively. Matrix effects were minimal across proteolytic type A Giorgio-A, nonproteolytic types QC-B and 202-F, and C. sporogenes PA3679 spore suspensions (90.1–114% of spiked DPA concentrations). DPA recovery in carrot juice and beef broth ranged from 105 to 118%, indicating limited matrix effects of these food products. Experiments that assessed the DPA released from Giorgio-A spores over the course of a 5-min thermal treatment at 108 °C found a significant correlation (R = 0.907; P < 0.05) between the log reduction of spores and amount of DPA released. This mixed-mode LC–MS/MS method provides a means for rapid detection of DPA released from C. botulinum spores during thermal processing and has the potential to be used for experiments in the field of food safety that assess the thermal resistance characteristics of various C. botulinum spore types.
    Keywords Clostridium botulinum ; Clostridium sporogenes ; analytical chemistry ; beef ; carrot juice ; electrospray ionization mass spectrometry ; food safety ; heat tolerance ; heat treatment ; liquid chromatography ; proteolysis ; rapid methods ; spores ; tandem mass spectrometry
    Language English
    Dates of publication 2022-03
    Size p. 2767-2774.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    ISSN 1618-2642
    DOI 10.1007/s00216-022-03926-7
    Database NAL-Catalogue (AGRICOLA)

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  9. Article: Ising-like models for stacking faults in a free electron metal.

    Ruffino, Martina / Skinner, Guy C G / Andritsos, Eleftherios I / Paxton, Anthony T

    Proceedings. Mathematical, physical, and engineering sciences

    2020  Volume 476, Issue 2242, Page(s) 20200319

    Abstract: We propose an extension of the axial next nearest neighbour Ising (ANNNI) model to a general number of interactions between spins. We apply this to the calculation of stacking fault energies in magnesium-particularly challenging due to the long-ranged ... ...

    Abstract We propose an extension of the axial next nearest neighbour Ising (ANNNI) model to a general number of interactions between spins. We apply this to the calculation of stacking fault energies in magnesium-particularly challenging due to the long-ranged screening of the pseudopotential by the free electron gas. We employ both density functional theory (DFT) using highest possible precision, and generalized pseudopotential theory (GPT) in the form of an analytic, long ranged, oscillating pair potential. At the level of first neighbours, the Ising model is reasonably accurate, but higher order terms are required. In fact, our ' AN
    Language English
    Publishing date 2020-10-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 209241-4
    ISSN 1471-2946 ; 1364-5021 ; 0962-8444 ; 0080-4630 ; 0950-1207
    ISSN (online) 1471-2946
    ISSN 1364-5021 ; 0962-8444 ; 0080-4630 ; 0950-1207
    DOI 10.1098/rspa.2020.0319
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Rapid detection and quantitation of dipicolinic acid from Clostridium botulinum spores using mixed-mode liquid chromatography-tandem mass spectrometry.

    Redan, Benjamin W / Morrissey, Travis R / Rolfe, Catherine A / Aguilar, Viviana L / Skinner, Guy E / Reddy, N Rukma

    Analytical and bioanalytical chemistry

    2022  Volume 414, Issue 8, Page(s) 2767–2774

    Abstract: Analysis of the dipicolinic acid (DPA) released from Clostridium botulinum spores during thermal processing is crucial to obtaining a mechanistic understanding of the factors involved in spore heat resistance and related food safety applications. Here, ... ...

    Abstract Analysis of the dipicolinic acid (DPA) released from Clostridium botulinum spores during thermal processing is crucial to obtaining a mechanistic understanding of the factors involved in spore heat resistance and related food safety applications. Here, we developed a novel mixed-mode liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for detection of the DPA released from C. botulinum type A, nonproteolytic types B and F strains, and nonpathogenic surrogate Clostridium sporogenes PA3679 spores. DPA was retained on a mixed-mode C18/anion exchange column and was detected using electrospray ionization (ESI) positive mode within a 4-min analysis time. The intraday and interday precision (%CV) was 1.94-3.46% and 4.04-8.28%, respectively. Matrix effects were minimal across proteolytic type A Giorgio-A, nonproteolytic types QC-B and 202-F, and C. sporogenes PA3679 spore suspensions (90.1-114% of spiked DPA concentrations). DPA recovery in carrot juice and beef broth ranged from 105 to 118%, indicating limited matrix effects of these food products. Experiments that assessed the DPA released from Giorgio-A spores over the course of a 5-min thermal treatment at 108 °C found a significant correlation (R = 0.907; P < 0.05) between the log reduction of spores and amount of DPA released. This mixed-mode LC-MS/MS method provides a means for rapid detection of DPA released from C. botulinum spores during thermal processing and has the potential to be used for experiments in the field of food safety that assess the thermal resistance characteristics of various C. botulinum spore types.
    MeSH term(s) Chromatography, Liquid ; Clostridium botulinum/chemistry ; Hot Temperature ; Picolinic Acids/analysis ; Spores, Bacterial/chemistry ; Tandem Mass Spectrometry
    Chemical Substances Picolinic Acids ; dipicolinic acid (UE81S5CQ0G)
    Language English
    Publishing date 2022-02-02
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 201093-8
    ISSN 1618-2650 ; 0016-1152 ; 0372-7920
    ISSN (online) 1618-2650
    ISSN 0016-1152 ; 0372-7920
    DOI 10.1007/s00216-022-03926-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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