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  1. Article ; Online: Solving musculoskeletal biomechanics with machine learning.

    Smirnov, Yaroslav / Smirnov, Denys / Popov, Anton / Yakovenko, Sergiy

    PeerJ. Computer science

    2021  Volume 7, Page(s) e663

    Abstract: Deep learning is a relatively new computational technique for the description of the musculoskeletal dynamics. The experimental relationships of muscle geometry in different postures are the high-dimensional spatial transformations that can be ... ...

    Abstract Deep learning is a relatively new computational technique for the description of the musculoskeletal dynamics. The experimental relationships of muscle geometry in different postures are the high-dimensional spatial transformations that can be approximated by relatively simple functions, which opens the opportunity for machine learning (ML) applications. In this study, we challenged general ML algorithms with the problem of approximating the posture-dependent moment arm and muscle length relationships of the human arm and hand muscles. We used two types of algorithms, light gradient boosting machine (LGB) and fully connected artificial neural network (ANN) solving the wrapping kinematics of 33 muscles spanning up to six degrees of freedom (DOF) each for the arm and hand model with 18 DOFs. The input-output training and testing datasets, where joint angles were the input and the muscle length and moment arms were the output, were generated by our previous phenomenological model based on the autogenerated polynomial structures. Both models achieved a similar level of errors: ANN model errors were 0.08 ± 0.05% for muscle lengths and 0.53 ± 0.29% for moment arms, and LGB model made similar errors-0.18 ± 0.06% and 0.13 ± 0.07%, respectively. LGB model reached the training goal with only 10
    Language English
    Publishing date 2021-08-26
    Publishing country United States
    Document type Journal Article
    ISSN 2376-5992
    ISSN (online) 2376-5992
    DOI 10.7717/peerj-cs.663
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Justification of the line of action for reclamation of lands disturbed by opencast mining

    Smirnov Y.D. / Suchkov D.V. / Goryunova T.V.

    E3S Web of Conferences, Vol 266, p

    2021  Volume 08009

    Abstract: The article is devoted to the substantiation of the line of action for reclamationof disturbed lands. The object of reclamation is a land plot (Russia, Leningrad Region), disturbed as a result of unauthorized open-pit mining operations for the extraction ...

    Abstract The article is devoted to the substantiation of the line of action for reclamationof disturbed lands. The object of reclamation is a land plot (Russia, Leningrad Region), disturbed as a result of unauthorized open-pit mining operations for the extraction of limestone. In order to obtain the information necessary to justify the reclamation project, the following works were carried out: reconnaissance and route observations, topographic, geological, and environmental surveys of the land. Based on the results of the generalized study data of the environmental and economic justification, a line of action for agricultural reclamation was chosen. In addition, an assessment of the estimated cost of the event was carried out and a list of necessary works was proposed within the framework of the technical and biological stages of reclamation.
    Keywords Environmental sciences ; GE1-350
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Justification of the line of action for reclamation of lands disturbed by opencast mining

    Smirnov Y.D. / Suchkov D.V. / Goryunova T.V.

    E3S Web of Conferences, Vol 266, p

    2021  Volume 08005

    Abstract: The article is devoted to the substantiation of the line of action for reclamationof disturbed lands. The object of reclamation is a land plot (Russia, Leningrad Region), disturbed as a result of unauthorized open-pit mining operations for the extraction ...

    Abstract The article is devoted to the substantiation of the line of action for reclamationof disturbed lands. The object of reclamation is a land plot (Russia, Leningrad Region), disturbed as a result of unauthorized open-pit mining operations for the extraction of limestone. In order to obtain the information necessary to justify the reclamation project, the following works were carried out: reconnaissance and route observations, topographic, geological, and environmental surveys of the land. Based on the results of the generalized study data of the environmental and economic justification, a line of action for agricultural reclamation was chosen. In addition, an assessment of the estimated cost of the event was carried out and a list of necessary works was proposed within the framework of the technical and biological stages of reclamation.
    Keywords Environmental sciences ; GE1-350
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Effect of 5-day dry immersion on the human foot morphology evaluated by computer plantography and soft tissues stiffness measuring.

    Saveko, Alina / Amirova, Liubov / Ermakov, Ivan / Smirnov, Yuri / Tomilovskaya, Elena / Kozlovskaya, Inesa

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 6232

    Abstract: 16 participants have been subjected to Dry Immersion model (DI) for 5 days. DI reproduces the space flight factors such as lack of support, mechanical and axial unloading, physical inactivity, elimination of vertical vascular gradient. Long-term bed rest ...

    Abstract 16 participants have been subjected to Dry Immersion model (DI) for 5 days. DI reproduces the space flight factors such as lack of support, mechanical and axial unloading, physical inactivity, elimination of vertical vascular gradient. Long-term bed rest is also associated with similar factors, so the results of the study may be useful for clinical medicine. Computer plantography and measuring the stiffness of the soft tissues of the foot and superficial muscles of the shin (mm. tibialis anterior and peroneus longus) were performed twice before DI exposure, on the 2nd and 4th days of DI exposure, as well as on the 2nd day of the recovery period. DI exposure effects the parameters under study in two ways: by raising the longitudinal arch and by flattening the transverse arch, which is accompanied by a decrease in the soft tissues stiffness of the foot and superficial muscles of the shin. The work reveals the phenomenon of compensating the longitudinal arch state by changing the characteristics that reflect the transverse arch state. The results of the study for the first time demonstrate the correlation of the foot morphological characteristics with a decrease in stiffness of mm. peroneus longus and tibialis anterior.
    MeSH term(s) Adult ; Biomechanical Phenomena ; Foot ; Hindlimb Suspension/instrumentation ; Hindlimb Suspension/methods ; Humans ; Male ; Muscle, Skeletal/physiology ; Sedentary Behavior ; Weightlessness Simulation
    Language English
    Publishing date 2021-03-18
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-85771-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Color Tuning of Electrochromic TiO

    Eyovge, Cavit / Deenen, Cristian S / Ruiz-Zepeda, Francisco / Bartling, Stephan / Smirnov, Yury / Morales-Masis, Monica / Susarrey-Arce, Arturo / Gardeniers, Han

    ACS applied nano materials

    2021  Volume 4, Issue 8, Page(s) 8600–8610

    Abstract: Co-axial electrospinning was applied for the structuring of non-woven webs of ... ...

    Abstract Co-axial electrospinning was applied for the structuring of non-woven webs of TiO
    Language English
    Publishing date 2021-08-16
    Publishing country United States
    Document type Journal Article
    ISSN 2574-0970
    ISSN (online) 2574-0970
    DOI 10.1021/acsanm.1c02231
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Propagation of TE waves in cylindrical nonlinear dielectric waveguides.

    Schürmann, H W / Smirnov, Y / Shestopalov, Y

    Physical review. E, Statistical, nonlinear, and soft matter physics

    2005  Volume 71, Issue 1 Pt 2, Page(s) 16614

    Abstract: The propagation of TE-polarized electromagnetic waves along a Kerr-type nonlinear dielectric, nonabsorbing, nonmagnetic, and isotropic (circular) cylindrical waveguide is investigated. For axially (azimuthal) symmetric solutions the problem is reduced to ...

    Abstract The propagation of TE-polarized electromagnetic waves along a Kerr-type nonlinear dielectric, nonabsorbing, nonmagnetic, and isotropic (circular) cylindrical waveguide is investigated. For axially (azimuthal) symmetric solutions the problem is reduced to a cubic-nonlinear integral equation that is solved by iteration leading to a sequence uniformly convergent to the solution of the integral equation. The dispersion relations associated to the exact and iterate solutions, respectively, are derived and solved, subject to certain constraints. The roots of the exact dispersion relation are approximated by the roots of the dispersion relations generated by the iterate solutions. All statements of existence and convergence are based on results of a previous paper. Numerical results (concerning solutions of dispersion relations, field patterns, dependence of the propagation constant and of the cutoff radius on the nonlinearity parameter, power flow) are included.
    Language English
    Publishing date 2005-01
    Publishing country United States
    Document type Journal Article
    ISSN 1539-3755
    ISSN 1539-3755
    DOI 10.1103/PhysRevE.71.016614
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Immunological assessment of plant-derived avian flu H5/HA1 variants.

    Spitsin, S / Andrianov, V / Pogrebnyak, N / Smirnov, Y / Borisjuk, N / Portocarrero, C / Veguilla, V / Koprowski, H / Golovkin, M

    Vaccine

    2009  Volume 27, Issue 9, Page(s) 1289–1292

    Abstract: Polypeptide variants of the HA1 antigenic domain of the H5N1 avian influenza virus hemagglutinin (HA) molecule were produced in plants using transient and stable expression systems and fused with His/c-myc tags or with mouse or human Fc antibody ... ...

    Abstract Polypeptide variants of the HA1 antigenic domain of the H5N1 avian influenza virus hemagglutinin (HA) molecule were produced in plants using transient and stable expression systems and fused with His/c-myc tags or with mouse or human Fc antibody fragments. The resulting peptides were purified and used for intramuscular immunization of mice. While the recombinant HA1 variants induced a significant serum humoral immune response in the mice, none of the HA1 preparations induced virus-neutralizing antibodies. Fusion with the Fc fragment improved overall yield of the constructs and allowed purification requiring only a single step, but led to no detectable fusion-related enhancement of immunogenicity or quality of immune response.
    MeSH term(s) Animals ; Antibody Formation ; Birds ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Influenza A Virus, H5N1 Subtype/immunology ; Influenza Vaccines/immunology ; Influenza in Birds/genetics ; Influenza in Birds/immunology ; Mice ; Mice, Inbred BALB C ; Plant Proteins/immunology
    Chemical Substances Influenza Vaccines ; Plant Proteins
    Keywords covid19
    Language English
    Publishing date 2009-02-25
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 605674-x
    ISSN 1873-2518 ; 0264-410X
    ISSN (online) 1873-2518
    ISSN 0264-410X
    DOI 10.1016/j.vaccine.2008.12.050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Online: Single-source, solvent-free, room temperature deposition of black $\gamma$-CsSnI$_3$ films

    Kiyek, Vivien M. / Birkhölzer, Yorick A. / Smirnov, Yury / Ledinsky, Martin / Remes, Zdenek / Momand, Jamo / Kooi, Bart J. / Koster, Gertjan / Rijnders, Guus / Morales-Masis, Monica

    2020  

    Abstract: The presence of a non-optically active polymorph (yellow-phase) competing with the optically active polymorph (black $\gamma$-phase) at room temperature in CsSnI3 and the susceptibility of Sn to oxidation, represent two of the biggest obstacles for the ... ...

    Abstract The presence of a non-optically active polymorph (yellow-phase) competing with the optically active polymorph (black $\gamma$-phase) at room temperature in CsSnI3 and the susceptibility of Sn to oxidation, represent two of the biggest obstacles for the exploitation of CsSnI3 in optoelectronic devices. Here room-temperature single-source in vacuum deposition of smooth black $\gamma$ - CsSnI3 thin films is reported. This has been done by fabricating a solid target by completely solvent-free mixing of CsI and SnI2 powders and isostatic pressing. By controlled laser ablation of the solid target on an arbitrary substrate at room temperature, the formation of CsSnI3 thin films with optimal optical properties is demonstrated. The films present a band gap of 1.32 eV, a sharp absorption edge and near-infrared photoluminescence emission. These properties and X-ray diffraction of the thin films confirmed the formation of the orthorhombic (B-$\gamma$) perovskite phase. The thermal stability of the phase was ensured by applying in situ an Al2O$_3$ capping layer. This work demonstrates the potential of pulsed laser deposition as a volatility-insensitive single-source growth technique of halide perovskites and represents a critical step forward in the development and future scalability of inorganic lead-free halide perovskites.

    Comment: Accepted by Advanced Materials Interfaces, 16 pages, 4 figures, and supplement
    Keywords Physics - Applied Physics ; Condensed Matter - Materials Science
    Subject code 530
    Publishing date 2020-04-29
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Peculiarities of the cellular ion-transport function of the gastrointestinal tract in hypertensive rats.

    Smirnov, Y / Oslopov, V / Sorokina, N / Maklakov, A / Stolpner, E

    Clinical and experimental pharmacology & physiology. Supplement

    1995  Volume 22, Issue 1, Page(s) S218–9

    Abstract: 1. A study of gastric and intestinal mucosa samples of 15 SHR and 15 normotensive rats of the line WKY was performed by proton-pulsed NMR with a pulsed magnetic field gradient. 2. The diffusion decay shape under the effect of the magnetic field gradient ... ...

    Abstract 1. A study of gastric and intestinal mucosa samples of 15 SHR and 15 normotensive rats of the line WKY was performed by proton-pulsed NMR with a pulsed magnetic field gradient. 2. The diffusion decay shape under the effect of the magnetic field gradient for intestinal mucosa cells in SHR and WKY appeared to be similar and differed drastically for gastric mucosa cells. The signal population of slow protons in SHR was lower and, with regard to fast protons, was higher than that in WKY. 3. The amount of slow protons is connected with low molecular cytoskeleton proteins. The decrease of their amount in hypertensive rats can be used as a test for cell membrane defects and explains, to some extent, the increase of membrane permeability for ions in the case of essential hypertension. This phenomenon is observed only in an acid medium (with increased proton concentration).
    MeSH term(s) Animals ; Biological Transport, Active/physiology ; Cell Membrane/metabolism ; Cytoskeletal Proteins/metabolism ; Diffusion ; Digestive System/cytology ; Digestive System/metabolism ; Gastric Mucosa/metabolism ; Hypertension/genetics ; Hypertension/metabolism ; Magnetic Resonance Spectroscopy ; Protons ; Rats ; Rats, Inbred SHR ; Rats, Inbred WKY
    Chemical Substances Cytoskeletal Proteins ; Protons
    Language English
    Publishing date 1995-12
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 189277-0
    ISSN 1440-1681 ; 0143-9294 ; 0305-1870
    ISSN (online) 1440-1681
    ISSN 0143-9294 ; 0305-1870
    DOI 10.1111/j.1440-1681.1995.tb02889.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Acousto-optic interaction in alpha-BaB(2)O(4)and Li(2)B(4)O(7) crystals.

    Martynyuk-Lototska, Irina / Mys, Oksana / Dudok, Taras / Adamiv, Volodymyr / Smirnov, Yevgen / Vlokh, Rostyslav

    Applied optics

    2008  Volume 47, Issue 19, Page(s) 3446–3454

    Abstract: Experimental studies and analysis of acousto-optic diffraction in alpha-BaB(2)O(4) and Li(2)B(4)O(7) crystals are given. Ultrasonic wave velocity, elastic compliance and stiffness coefficients, and piezo-optic and photoelastic coefficients of alpha-BaB(2) ...

    Abstract Experimental studies and analysis of acousto-optic diffraction in alpha-BaB(2)O(4) and Li(2)B(4)O(7) crystals are given. Ultrasonic wave velocity, elastic compliance and stiffness coefficients, and piezo-optic and photoelastic coefficients of alpha-BaB(2)O(4) and Li(2)B(4)O(7) crystals are determined. The acousto-optic figure of merit has been estimated for different possible geometries of acousto-optic interaction. It is shown that the acousto-optic figures of merit for alpha-BaB(2)O(4) crystals reach the value M(2)=(270 +/- 70) x 10(-15) s(3)/kg for the case of interaction with the slowest ultrasonic wave. The directions of propagation and polarization of those acoustic waves are obtained on the basis of construction of acoustic slowness surfaces. The acousto-optic diffraction is experimentally studied for alpha-BaB(2)O(4) and Li(2)B(4)O(7) crystals.
    Language English
    Publishing date 2008-06-04
    Publishing country United States
    Document type Journal Article
    ISSN 1559-128X
    ISSN 1559-128X
    DOI 10.1364/ao.47.003446
    Database MEDical Literature Analysis and Retrieval System OnLINE

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