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  1. Article ; Online: Characteristics of and Deaths among 333 Persons with Tuberculosis and COVID-19 in Cross-Sectional Sample from 25 Jurisdictions, United States.

    Nabity, Scott A / Marks, Suzanne M / Goswami, Neela D / Smith, Shona R / Timme, Evan / Price, Sandy F / Gross, Lon / Self, Julie L / Toren, Katelynne Gardner / Narita, Masahiro / Wegener, Donna H / Wang, Shu-Hua

    Emerging infectious diseases

    2023  Volume 29, Issue 10, Page(s) 2016–2023

    Abstract: Little is known about co-occurring tuberculosis (TB) and COVID-19 in low TB incidence settings. We obtained a cross-section of 333 persons in the United States co-diagnosed with TB and COVID-19 within 180 days and compared them to 4,433 persons with TB ... ...

    Abstract Little is known about co-occurring tuberculosis (TB) and COVID-19 in low TB incidence settings. We obtained a cross-section of 333 persons in the United States co-diagnosed with TB and COVID-19 within 180 days and compared them to 4,433 persons with TB only in 2020 and 18,898 persons with TB during 2017‒2019. Across both comparison groups, a higher proportion of persons with TB-COVID-19 were Hispanic, were long-term care facility residents, and had diabetes. When adjusted for age, underlying conditions, and TB severity, COVID-19 co-infection was not statistically associated with death compared with TB infection only in 2020 (adjusted prevalence ratio 1.0 [95% CI 0.8‒1.4]). Among TB-COVID-19 patients, death was associated with a shorter interval between TB and COVID-19 diagnoses, older age, and being immunocompromised (non-HIV). TB-COVID-19 deaths in the United States appear to be concentrated in subgroups sharing characteristics known to increase risk for death from either disease alone.
    MeSH term(s) Humans ; COVID-19/mortality ; Cross-Sectional Studies ; Tuberculosis/mortality ; United States/epidemiology
    Language English
    Publishing date 2023-08-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid2910.230286
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4778: Show issues Location:
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  2. Article ; Online: Second Nationwide Tuberculosis Outbreak Caused by Bone Allografts Containing Live Cells - United States, 2023.

    Wortham, Jonathan M / Haddad, Maryam B / Stewart, Rebekah J / Annambhotla, Pallavi / Basavaraju, Sridhar V / Nabity, Scott A / Griffin, Isabel S / McDonald, Emily / Beshearse, Elizabeth M / Grossman, Marissa K / Schildknecht, Kimberly R / Calvet, Helene M / Keh, Chris E / Percak, Jeffrey M / Coloma, Myron / Shaw, Tambi / Davidson, Peter J / Smith, Shona R / Dickson, Robert P /
    Kaul, Daniel R / Gonzalez, Annett R / Rai, Saroj / Rodriguez, Gretchen / Morris, Sandra / Armitige, Lisa Y / Stapleton, Jessica / Lacassagne, Michael / Young, Laura R / Ariail, Kiley / Behm, Heidi / Jordan, Hannah T / Spencer, Magdalene / Nilsen, Diana M / Denison, Brenda Montoya / Burgos, Marcos / Leonard, Juliet M / Cortes, Erick / Thacker, Tyler C / Lehman, Kimberly A / Langer, Adam J / Cowan, Lauren S / Starks, Angela M / LoBue, Philip A

    MMWR. Morbidity and mortality weekly report

    2024  Volume 72, Issue 5253, Page(s) 1385–1389

    Abstract: During July 7-11, 2023, CDC received reports of two patients in different states with a tuberculosis (TB) diagnosis following spinal surgical procedures that used bone allografts containing live cells from the same deceased donor. An outbreak associated ... ...

    Abstract During July 7-11, 2023, CDC received reports of two patients in different states with a tuberculosis (TB) diagnosis following spinal surgical procedures that used bone allografts containing live cells from the same deceased donor. An outbreak associated with a similar product manufactured by the same tissue establishment (i.e., manufacturer) occurred in 2021. Because of concern that these cases represented a second outbreak, CDC and the Food and Drug Administration worked with the tissue establishment to determine that this product was obtained from a donor different from the one implicated in the 2021 outbreak and learned that the bone allograft product was distributed to 13 health care facilities in seven states. Notifications to all seven states occurred on July 12. As of December 20, 2023, five of 36 surgical bone allograft recipients received laboratory-confirmed TB disease diagnoses; two patients died of TB. Whole-genome sequencing demonstrated close genetic relatedness between positive Mycobacterium tuberculosis cultures from surgical recipients and unused product. Although the bone product had tested negative by nucleic acid amplification testing before distribution, M. tuberculosis culture of unused product was not performed until after the outbreak was recognized. The public health response prevented up to 53 additional surgical procedures using allografts from that donor; additional measures to protect patients from tissue-transmitted M. tuberculosis are urgently needed.
    MeSH term(s) Humans ; United States/epidemiology ; Tuberculosis/epidemiology ; Tuberculosis/diagnosis ; Mycobacterium tuberculosis/genetics ; Tissue Donors ; Disease Outbreaks ; Allografts
    Language English
    Publishing date 2024-01-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 412775-4
    ISSN 1545-861X ; 0149-2195
    ISSN (online) 1545-861X
    ISSN 0149-2195
    DOI 10.15585/mmwr.mm725253a1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1827: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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