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  1. Book ; Online ; E-Book: The environmental policy paradox

    Smith, Zachary A. / Jacques, Peter

    2022  

    Author's details Zachary A. Smith, Peter J. Jacques
    Keywords Environmental policy
    Subject code 363.700973
    Language English
    Size 1 online resource (487 pages)
    Edition Eighth edition.
    Publisher Routledge
    Publishing place New York, New York ; London, England
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-00-309803-7 ; 1-003-09803-7 ; 1-000-77474-0 ; 9780367557324 ; 978-1-00-309803-4 ; 978-1-003-09803-4 ; 978-1-000-77474-0 ; 0367557320
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Book: Minimally invasive spine surgery

    Smith, Zachary A.

    (Neurosurgery clinics of North America ; 25,2)

    2014  

    Author's details ed. Zachary A. Smith
    Series title Neurosurgery clinics of North America ; 25,2
    Collection
    Language English
    Size XI S., S. 212 - 385 : zahlr. Ill.
    Publisher Elsevier
    Publishing place New York, NY u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT018275331
    ISBN 978-0-323-29004-3 ; 0-323-29004-3
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Se 1200 -25,2- verfügbar in Königswinter Königswinter

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  3. Book: Energy use worldwide

    Moan, Jaina L. / Smith, Zachary A.

    a reference handbook

    (Contemporary world issues)

    2007  

    Author's details Jaina L. Moan and Zachary A. Smith
    Series title Contemporary world issues
    Language English
    Size XVI, 337 S. : graph. Darst.
    Publisher ABC-Clio
    Publishing place Santa Barbara, Calif. u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT015104293
    ISBN 978-1-85109-890-3 ; 1-85109-890-9
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    078/1462 available for loan (reading room) Freihandmagazin (U1)

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  4. Article ; Online: Examining the Association Between DCT Solutions Use and Participant Diversity in Clinical Trials.

    Smith, Zachary / Getz, Kenneth

    Therapeutic innovation & regulatory science

    2024  

    Abstract: Background: Whereas anecdotal reports suggest that the use of decentralized clinical trial (DCT) solutions can improve participant diversity in clinical trials there is no quantitative evidence to support such reports.: Methods: Tufts CSDD conducted ... ...

    Abstract Background: Whereas anecdotal reports suggest that the use of decentralized clinical trial (DCT) solutions can improve participant diversity in clinical trials there is no quantitative evidence to support such reports.
    Methods: Tufts CSDD conducted this initial study based on data collected from prior research and publicly available data drawn from Clinicaltrials.gov to compare and contrast participant diversity in trials which included various DCT solutions - virtual visits or televisits, home visits, devices or wearables, and the use of local labs.
    Results: The results of this analysis indicate that the use of local labs is associated with a lower percentage of white participants; the use of virtual visits or televisits is associated with a lower percentage of Black participants; and the use of devices or wearables was not associated with any significant change in participant demographics. The use of home visits could not be tested for significant differences.
    Language English
    Publishing date 2024-05-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2708397-4
    ISSN 2168-4804 ; 2168-4790
    ISSN (online) 2168-4804
    ISSN 2168-4790
    DOI 10.1007/s43441-024-00659-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Better standards are needed for membrane materials.

    Lee, Tae Hoon / Smith, Zachary P

    Nature materials

    2024  Volume 23, Issue 1, Page(s) 11–12

    Language English
    Publishing date 2024-01-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2088679-2
    ISSN 1476-4660 ; 1476-1122
    ISSN (online) 1476-4660
    ISSN 1476-1122
    DOI 10.1038/s41563-023-01763-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A Diagnostic Biomarker for Cervical Myelopathy Based on Dynamic Magnetic Resonance Imaging.

    Muhammad, Fauziyya / Smith, Zachary A

    Spine

    2023  Volume 48, Issue 24, Page(s) E420–E421

    MeSH term(s) Humans ; Spinal Cord Diseases/diagnostic imaging ; Magnetic Resonance Imaging/methods ; Biomarkers ; Cervical Vertebrae/diagnostic imaging ; Spinal Cord Compression/diagnosis
    Chemical Substances Biomarkers
    Language English
    Publishing date 2023-06-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 752024-4
    ISSN 1528-1159 ; 0362-2436
    ISSN (online) 1528-1159
    ISSN 0362-2436
    DOI 10.1097/BRS.0000000000004744
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1305: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: A Case Study Assessment on the Rationale for, and Relevance of, Non-Core Protocol Data.

    Smith, Zachary / Getz, Kenneth

    Therapeutic innovation & regulatory science

    2023  Volume 58, Issue 2, Page(s) 311–315

    Abstract: To better understand the nature of Non-Core procedures and derive new insight into protocol simplification and optimization, Tufts CSDD collaborated with the FDA and sponsor companies to assess alignment on the rationale for collecting, and relevance of, ...

    Abstract To better understand the nature of Non-Core procedures and derive new insight into protocol simplification and optimization, Tufts CSDD collaborated with the FDA and sponsor companies to assess alignment on the rationale for collecting, and relevance of, Non-Core protocol data. Twelve sponsor companies classified and rated 700 distinct procedures from 19 pivotal trials supporting new drug and biologics approvals. FDA reviewers classified and rated 80 distinct procedures for three of the 19 pivotal trials. The results of this assessment indicate areas of alignment and misalignment. Sponsors and FDA reviewers agreed on the classification for more than half of endpoints. However, FDA reviewers classified a much higher percentage of procedures as Non-Core (26% vs. 18%) with the largest proportion (50%) of these procedures perceived as Core by sponsor companies. Sponsors indicated that one-out-of-six Non-Core procedures were administered due to perceived regulatory requirement and expectation. The results of this study characterize the challenge in aligning the different-and potentially conflicting-imperatives of sponsors and regulators and speak to the importance of more effective FDA-sponsor communication to help simplify protocol designs.
    MeSH term(s) United States ; United States Food and Drug Administration ; Biological Products
    Chemical Substances Biological Products
    Language English
    Publishing date 2023-12-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2708397-4
    ISSN 2168-4804 ; 2168-4790
    ISSN (online) 2168-4804
    ISSN 2168-4790
    DOI 10.1007/s43441-023-00595-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Effects of alerting signals on the spatial Stroop effect: evidence for modality differences.

    Kahan, Todd A / Smith, Zachary P

    Psychological research

    2023  Volume 88, Issue 1, Page(s) 25–38

    Abstract: Reaction times and error rates to a target's identity are impaired when the target is presented in a location that mismatches the response required, relative to situations where the location of the target and required response overlap (the Simon effect) ... ...

    Abstract Reaction times and error rates to a target's identity are impaired when the target is presented in a location that mismatches the response required, relative to situations where the location of the target and required response overlap (the Simon effect) and the same is true when the target's identity conveys spatial information (the spatial Stroop effect). Prior studies have found that visual versions of the spatial Stroop effect are magnified when alerting cues appear before the target and results are consistent with a dual-route framework where alerting cues boost automatic stimulus-response motor associations through the direct processing route. However, the influence of alerting signals on auditory versions of the spatial Stroop effect have not been tested and there are reasons to believe that the alerting-congruency interaction may differ across stimulus modality. In two experiments the effects of alerting cues on auditory (Experiment 1; N = 98) and visual (Experiment 2; N = 97) spatial Stroop effects are examined. Results show that alerting cues boost the spatial Stroop effect with visual stimuli but not auditory stimuli and a distributional analysis provides support for there being modality differences in the decay (or inhibition) of response-code activation. Implications for explanations of the alerting-congruence interaction are discussed.
    MeSH term(s) Humans ; Attention/physiology ; Stroop Test ; Reaction Time/physiology ; Cues ; Inhibition, Psychological
    Language English
    Publishing date 2023-06-30
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1463034-5
    ISSN 1430-2772 ; 0340-0727
    ISSN (online) 1430-2772
    ISSN 0340-0727
    DOI 10.1007/s00426-023-01846-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: New Benchmarks on Protocol Amendment Experience in Oncology Clinical Trials.

    Botto, Emily / Smith, Zachary / Getz, Kenneth

    Therapeutic innovation & regulatory science

    2024  

    Abstract: Background: The drug development industry's focus on cancer-related treatments continues to rise, with narrow patient populations and complex procedures increasing the complexity of oncology protocols at an accelerated rate compared to non-oncology ... ...

    Abstract Background: The drug development industry's focus on cancer-related treatments continues to rise, with narrow patient populations and complex procedures increasing the complexity of oncology protocols at an accelerated rate compared to non-oncology drugs. Tufts Center for the Study of Drug Development utilized data from a study investigating the impact of protocol amendments to compare how oncology clinical trials differ from non-oncology and identify opportunities to optimize performance in oncology clinical trials.
    Methods: Sixteen drug development industry companies contributed data from 950 protocols and 2,188 amendments to a study conducted in 2022 investigating protocol amendments. Analysis compared differences in amendment impact and causes between 249 oncology and 701 non-oncology protocols.
    Results: Compared to non-oncology, oncology protocols had a significantly higher prevalence (72.1% and 91.1%, respectively) and number (3.0 and 4.0, respectively) of protocol amendments. Oncology protocols with amendments had significantly lower participant completion rates compared to oncology protocols without amendments, while no significant differences were found among non-oncology. During the COVID-19 pandemic, the study found an increased number of substantial amendments, lower completion rates, and higher dropout rates among oncology protocols compared to before the pandemic.
    Conclusions: Efforts to prevent avoidable protocol amendments in the industry have not been effective in oncology, where increasingly complex designs are reflected in difficult to predict cycle times, barriers to recruitment and retention and an increase in protocol amendments.
    Language English
    Publishing date 2024-03-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2708397-4
    ISSN 2168-4804 ; 2168-4790
    ISSN (online) 2168-4804
    ISSN 2168-4790
    DOI 10.1007/s43441-024-00629-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Letter: Learning Curves for Robot-Assisted Pedicle Screw Placement: Analysis of Operative Time for 234 Cases.

    Smith, Zachary A / Muhammad, Fauziyya / Baaj, Ali A

    Operative neurosurgery (Hagerstown, Md.)

    2024  Volume 26, Issue 4, Page(s) 487–488

    MeSH term(s) Humans ; Robotics ; Pedicle Screws ; Learning Curve ; Operative Time ; Robotic Surgical Procedures
    Language English
    Publishing date 2024-02-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2767575-0
    ISSN 2332-4260 ; 2332-4252
    ISSN (online) 2332-4260
    ISSN 2332-4252
    DOI 10.1227/ons.0000000000001083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1424 -ON-: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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