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  1. Article ; Online: Correction to: Does the uterine microbiota affect the reproductive outcomes in women with recurrent implantation failures?

    Keburiya, Lela K / Smolnikova, Veronika Yu / Priputnevich, Tatiana V / Muravieva, Vera V / Gordeev, Alexey B / Trofimov, Dmitry Yu / Shubina, Ekaterina S / Kochetkova, Taisiya O / Rogacheva, Margarita S / Kalinina, Elena A / Sukhikh, Gennady T

    BMC women's health

    2023  Volume 23, Issue 1, Page(s) 265

    Language English
    Publishing date 2023-05-15
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2050444-5
    ISSN 1472-6874 ; 1472-6874
    ISSN (online) 1472-6874
    ISSN 1472-6874
    DOI 10.1186/s12905-023-02302-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Does the uterine microbiota affect the reproductive outcomes in women with recurrent implantation failures?

    Keburiya, Lela K / Smolnikova, Veronika Yu / Priputnevich, Tatiana V / Muravieva, Vera V / Gordeev, Alexey B / Trofimov, Dmitry Yu / Shubina, Ekaterina S / Kochetkova, Taisiya O / Rogacheva, Margarita S / Kalinina, Elena A / Sukhikh, Gennady T

    BMC women's health

    2022  Volume 22, Issue 1, Page(s) 168

    Abstract: Background: Inefficiency of in vitro fertilization (IVF) programs can be caused by implantation failures. The uterine microbiota can influence the implantation process. However, it still remains unclear whether opportunistic microorganisms detected in ... ...

    Abstract Background: Inefficiency of in vitro fertilization (IVF) programs can be caused by implantation failures. The uterine microbiota can influence the implantation process. However, it still remains unclear whether opportunistic microorganisms detected in the endometrium have a negative impact on the implantation success. The aim of our study was to evaluate the influence of the uterine microbiota on the embryo implantation success in patients undergoing assisted reproductive technologies.
    Methods: The study included 130 women diagnosed with infertility. The patients were divided into three groups: group I included women with the first IVF attempt (n = 39); group II included patients with recurrent implantation failure following embryo transfer with ovarian stimulation (n = 27); group III consisted of women with recurrent implantation failure following frozen-thawed embryo transfer (n = 64). We performed microbiological examination of the embryo transfer catheter which was removed from the uterine cavity after embryo transfer; cervical discharge of all the patients was studied as well. Thirty patients were selected for metagenomic sequencing.
    Results: The study showed that the uterine cavity is not free of microorganisms. A total of 44 species of microorganisms were detected: 26 species of opportunistic organisms and 18 species of commensals (14 species of lactobacilli and 4 species of bifidobacteria). Obligate anaerobic microorganisms and Gardnerella vaginalis were detected more frequently in group I compared to group III (strict anaerobes-15.4 and 1.6%; G. vaginalis-12.8 and 1.6%, respectively) (p < 0.05). However, this fact did not have a negative influence on the pregnancy rate: it was 51.3% in group I, it was 29.6% and 35.9% in women with recurrent implantation failures, respectively.
    Conclusion: Opportunistic microorganisms which were revealed in low or moderate titers (10
    MeSH term(s) Embryo Implantation ; Embryo Transfer ; Female ; Fertilization in Vitro ; Humans ; Microbiota ; Pregnancy ; Pregnancy Rate
    Language English
    Publishing date 2022-05-14
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2050444-5
    ISSN 1472-6874 ; 1472-6874
    ISSN (online) 1472-6874
    ISSN 1472-6874
    DOI 10.1186/s12905-022-01750-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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