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  1. Article ; Online: Wastewater treatment in 2050: Challenges ahead and future vision in a European context.

    Soares, Ana

    Environmental science and ecotechnology

    2020  Volume 2, Page(s) 100030

    Abstract: Wastewater treatment plants are slowly evolving.•In the next decade, successful implementation of technologies is focused intensification.•New technologies will be focused on gases and bio-based materials.•Academics need more freedom to develop novel ... ...

    Abstract •Wastewater treatment plants are slowly evolving.•In the next decade, successful implementation of technologies is focused intensification.•New technologies will be focused on gases and bio-based materials.•Academics need more freedom to develop novel concepts.•Collaborative platforms that enable demonstration of high-risk technologies is key.
    Language English
    Publishing date 2020-04-28
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2666-4984
    ISSN (online) 2666-4984
    DOI 10.1016/j.ese.2020.100030
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  2. Article ; Online: Development of an Internet-based system to guide and telemonitor hearing aid users.

    Soares, Andrea / Almeida, Katia de

    CoDAS

    2023  Volume 35, Issue 6, Page(s) e20220162

    Abstract: Purpose: To develop and verify the usability of an internet-based system for telemonitoring and guidance of the hearing aid user as well as monitoring the long-term performance in a pilot group.: Methods: The system "I can hear, but I can't ... ...

    Title translation Desenvolvimento de sistema baseado na internet para orientação e telemonitoramento de usuários de prótese auditiva.
    Abstract Purpose: To develop and verify the usability of an internet-based system for telemonitoring and guidance of the hearing aid user as well as monitoring the long-term performance in a pilot group.
    Methods: The system "I can hear, but I can't understand" was developed based on recommendations in the literature regarding layout, design, and content for guidance and advice. Three stages were followed: planning, design and content development, and pilot testing. The sample consisted of 43 adults and older adults with any type and degree of hearing loss, who had been regularly using a hearing aid for at least 30 days and at most 24 months, with reading skills and no evidence of cognitive impairments. The individuals were followed up for 8 to 12 months. The users' performance was monitored with the Speech, Spatial and Qualities of Hearing Scale. The usability of this material was assessed with the System Usability Scale.
    Results: Improved performance and increased self-reported daily use of the hearing aid were observed after the period of guidance and telemonitoring via the system for all research participants. In all analyzes of the SUS scale, it was possible to observe a performance superior to 70 points, demonstrating good usability of the system. In the analysis of the performance of the SSQ, in the three moments of the research, a positive response was observed in all domains, thus showing progress in the use of hearing aids, with significant data for the domain of Hearing Speech.
    Conclusion: The system "I can hear, but I can't understand" proved to be an easy-to-use and effective tool to telemonitor hearing aid users.
    MeSH term(s) Humans ; Aged ; Hearing Aids ; Hearing Loss/rehabilitation ; Hearing ; Self Report ; Hearing Tests ; Speech Perception
    Language English
    Publishing date 2023-12-04
    Publishing country Brazil
    Document type Journal Article
    ISSN 2317-1782
    ISSN (online) 2317-1782
    DOI 10.1590/2317-1782/20232022162pt
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  3. Article ; Online: Health system financing paradigm in the state of São Paulo: a regional analysis.

    Soares, Adilson

    Revista de saude publica

    2019  Volume 53, Page(s) 39

    Abstract: Objective: To analyze the allocation of financial resources in the Brazilian Unified Health System (SUS) in the state of São Paulo by level of care, health region, source of funds and level of government.: Methods: This is an exploratory study based ... ...

    Abstract Objective: To analyze the allocation of financial resources in the Brazilian Unified Health System (SUS) in the state of São Paulo by level of care, health region, source of funds and level of government.
    Methods: This is an exploratory study based on 2014 data extracted from the Public Health Budget Database, presented in absolute terms, relative terms and per capita .
    Results: In 2014, R$52.1 bi were spent on public health, 58.0% having corresponded to the expenditures of the municipalities and 42.0% to those of the state government. Regional per capita spending varied from R$561.75 to R$824.85. As for the per capita spending on primary health care, which represented 37.5% of the municipalities' total expenditure, the lowest value was found in the city of São Paulo and the highest, in Araçatuba. Campinas had the highest per capita expenditure on medium and high complexity care, while Presidente Prudente had the lowest. The highest regional percentage of the current net revenue spent on health was verified in Registro, and the lowest, in the city of São Paulo.
    Conclusions: The paradigm of the health sector's financing in São Paulo revealed that the expenditure on primary health care, level elected by health policy as strategic because it depends on coordination and integral health care in the attention networks, was not considered a priority in relation to the expenditure with the medium and high complexity, exposing the iniquities in the state's regions.
    MeSH term(s) Brazil ; Budgets/statistics & numerical data ; Cities ; Financing, Government/economics ; Financing, Government/statistics & numerical data ; Health Care Rationing/economics ; Health Expenditures/statistics & numerical data ; Health Policy ; Healthcare Financing ; Humans ; National Health Programs/economics ; Reference Values
    Language Portuguese
    Publishing date 2019-05-06
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 732179-x
    ISSN 1518-8787 ; 0034-8910
    ISSN (online) 1518-8787
    ISSN 0034-8910
    DOI 10.11606/S1518-8787.2019053000796
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  4. Article ; Online: Active learning strategies for robotic tactile texture recognition tasks.

    Das, Shemonto / Prado da Fonseca, Vinicius / Soares, Amilcar

    Frontiers in robotics and AI

    2024  Volume 11, Page(s) 1281060

    Abstract: Accurate texture classification empowers robots to improve their perception and comprehension of the environment, enabling informed decision-making and appropriate responses to diverse materials and surfaces. Still, there are challenges for texture ... ...

    Abstract Accurate texture classification empowers robots to improve their perception and comprehension of the environment, enabling informed decision-making and appropriate responses to diverse materials and surfaces. Still, there are challenges for texture classification regarding the vast amount of time series data generated from robots' sensors. For instance, robots are anticipated to leverage human feedback during interactions with the environment, particularly in cases of misclassification or uncertainty. With the diversity of objects and textures in daily activities, Active Learning (AL) can be employed to minimize the number of samples the robot needs to request from humans, streamlining the learning process. In the present work, we use AL to select the most informative samples for annotation, thus reducing the human labeling effort required to achieve high performance for classifying textures. We also use a sliding window strategy for extracting features from the sensor's time series used in our experiments. Our multi-class dataset (e.g., 12 textures) challenges traditional AL strategies since standard techniques cannot control the number of instances per class selected to be labeled. Therefore, we propose a novel class-balancing instance selection algorithm that we integrate with standard AL strategies. Moreover, we evaluate the effect of sliding windows of two-time intervals (3 and 6 s) on our AL Strategies. Finally, we analyze in our experiments the performance of AL strategies, with and without the balancing algorithm, regarding f1-score, and positive effects are observed in terms of performance when using our proposed data pipeline. Our results show that the training data can be reduced to 70% using an AL strategy regardless of the machine learning model and reach, and in many cases, surpass a baseline performance. Finally, exploring the textures with a 6-s window achieves the best performance, and using either Extra Trees produces an average f1-score of 90.21% in the texture classification data set.
    Language English
    Publishing date 2024-02-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2781824-X
    ISSN 2296-9144 ; 2296-9144
    ISSN (online) 2296-9144
    ISSN 2296-9144
    DOI 10.3389/frobt.2024.1281060
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  5. Article ; Online: Facing treatment of non-urothelial bladder cancers in the immunotherapy era.

    Grilo, I / Rodrigues, C / Soares, A / Grande, E

    Critical reviews in oncology/hematology

    2020  Volume 153, Page(s) 103034

    Abstract: Non-urothelial Bladder Cancer (BC) and variants of urothelial carcinoma account for up to 25 % of all BCs. Given their heterogeneity, these entities are not well represented in clinical trials and treatment remains challenging. Checkpoint inhibitor ... ...

    Abstract Non-urothelial Bladder Cancer (BC) and variants of urothelial carcinoma account for up to 25 % of all BCs. Given their heterogeneity, these entities are not well represented in clinical trials and treatment remains challenging. Checkpoint inhibitor therapy has shown a role in the treatment of urothelial BC. By contrast, robust evidence regarding its use in other histological types is lacking. We aimed to provide a comprehensive update of non-urothelial and variant urothelial BC, exploring the evidence for immune checkpoint inhibitor therapy. A detailed analysis of the literature was conducted regarding epidemiology, aetiology, diagnosis, prognosis, treatment and outcomes of these patients in the immunotherapy era. A growing body of evidence suggests that immune checkpoint inhibition might have a role to play in non-urothelial BC, similarly to what happened with urothelial carcinomas.
    MeSH term(s) Carcinoma, Transitional Cell ; Humans ; Immunologic Factors ; Immunotherapy ; Urinary Bladder Neoplasms/therapy ; Urologic Neoplasms
    Chemical Substances Immunologic Factors
    Language English
    Publishing date 2020-06-20
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 605680-5
    ISSN 1879-0461 ; 0737-9587 ; 1040-8428
    ISSN (online) 1879-0461
    ISSN 0737-9587 ; 1040-8428
    DOI 10.1016/j.critrevonc.2020.103034
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  6. Article ; Online: Understanding the mechanisms of biological struvite biomineralisation.

    Leng, Yirong / Soares, Ana

    Chemosphere

    2021  Volume 281, Page(s) 130986

    Abstract: The mechanisms of struvite production through biomineralisation were investigated for five microorganisms (Bacillus pumilus, Brevibacterium antiquum, Myxococcus xanthus, Halobacterium salinarum and Idiomarina loihiensis). After 72-96 h of incubation, the ...

    Abstract The mechanisms of struvite production through biomineralisation were investigated for five microorganisms (Bacillus pumilus, Brevibacterium antiquum, Myxococcus xanthus, Halobacterium salinarum and Idiomarina loihiensis). After 72-96 h of incubation, the microbial strains tested increased the solution pH from 7.5 to 7.7 to 8.4-8.7, and removed ortho-phosphate (63-71%) and magnesium (94-99%) by biomineralisation. The minerals formed were identified as struvite (i.e. bio-struvite). Within the initial 24 h of incubation, microbial growth rates of 0.16-0.28 1/h were measured, and bio-struvite production was observed when the solution supersaturation index with respect to struvite achieved 0.6-0.8 units. The crystals produced by B. pumilus, H. salinarum and M. xanthus were thin trapezoidal-platy shaped and presented a gap size about 200 μm for intervals between cumulative volume undersize distribution at 50% and 90%. While B. antiquum and I. loihiensis produced crystals of coffin-lid/long-bar shape and a narrow size gap around 100 μm for intervals between cumulative volume percentage of 50% and 90%, indicating homogeneous crystal size distribution. Intracellular supersaturation of struvite phase was achieved within B. antiquum and I. loihiensis cells, corresponding to observation of intracellular vesicle-like structures occupied with electron-dense granules/materials. This study suggests that B. antiquum and I. loihiensis produced bio-struvite through biologically controlled mineralisation. This mechanism is the preferred for recovering nutrients from streams such as wastewater because it allows a link between manipulation of microbial growth conditions and bio-struvite production, even in highly complex streams like wastewater.
    MeSH term(s) Alteromonadaceae ; Brevibacterium ; Magnesium Compounds ; Phosphates ; Phosphorus ; Struvite
    Chemical Substances Magnesium Compounds ; Phosphates ; Phosphorus (27YLU75U4W) ; Struvite (AW3EJL1462)
    Language English
    Publishing date 2021-05-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2021.130986
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  7. Article ; Online: Recent Updates in the Treatment of Erythema Multiforme.

    Soares, Alexa / Sokumbi, Olayemi

    Medicina (Kaunas, Lithuania)

    2021  Volume 57, Issue 9

    Abstract: Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus ( ... ...

    Abstract Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. EM can be confused with other more serious conditions like Stevens-Johnson syndrome (SJS); however, clinical research has provided significant evidence to classify EM and SJS as separate disorders. Treatment of EM is highly variable, depending on the etiology, the involvement of mucosal sites, and the chronicity (acute vs. recurring) of the disease. If the etiology or causal medication/infection is identified, then the medication is stopped and/or the infection is treated prior to initiating symptomatic treatment. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials.
    MeSH term(s) Antiviral Agents/therapeutic use ; Erythema Multiforme/diagnosis ; Erythema Multiforme/drug therapy ; Humans ; Simplexvirus ; Skin ; Stevens-Johnson Syndrome/drug therapy
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2021-09-01
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina57090921
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  8. Article ; Online: The mechanisms of struvite biomineralization in municipal wastewater.

    Leng, Yirong / Soares, Ana

    The Science of the total environment

    2021  Volume 799, Page(s) 149261

    Abstract: The mechanisms of struvite production by biomineralization were investigated for five microorganisms (Bacillus pumilus, Brevibacterium antiquum, Myxococcus xanthus, Halobacterium salinarum and Idiomarina loihiensis) in municipal wastewater. The microbial ...

    Abstract The mechanisms of struvite production by biomineralization were investigated for five microorganisms (Bacillus pumilus, Brevibacterium antiquum, Myxococcus xanthus, Halobacterium salinarum and Idiomarina loihiensis) in municipal wastewater. The microbial exponential phase of growth occurred within the first 48 h of incubation, with growth rates varying from 0.02-0.08 1/h. These five microorganisms removed 23-27 mg/L (66-79%) of ortho-phosphate from wastewater, which was recovered as biological struvite (i.e., bio-struvite) identified by morphological, X-ray diffraction and elemental analysis. Bio-struvite crystals occurred in a low extracellular supersaturation index (0.6-0.8 units). Bio-struvite formation in B. pumilus M. xanthus, H. salinarum cultures was linked to biologically induced mineralization. Whereas B. antiquum and I. loihiensis produced bio-struvite through biologically controlled mineralization mechanism because the crystals presented homogeneity in morphology and size, and intracellular vesicle-like cell structures were observed enclosing electron-dense granules/materials. Nutrient recovery through biomineralization has potential application in wastewater streams promoting circularity within the wastewater industry.
    MeSH term(s) Alteromonadaceae ; Biomineralization ; Brevibacterium ; Phosphates ; Phosphorus ; Struvite ; Waste Water
    Chemical Substances Phosphates ; Waste Water ; Phosphorus (27YLU75U4W) ; Struvite (AW3EJL1462)
    Language English
    Publishing date 2021-07-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2021.149261
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  9. Article ; Online: In Vitro Evaluation of the Dynamic Cyclic Fatigue Resistance of a New TruNatomy Glider File after Different Cycles of Use.

    Rego, Lorena Ferreira / Bronzato, Juliana Delatorre / Souza, Alana Pinto Carôso / de-Jesus-Soares, Adriana / Frozoni, Marcos

    Journal of endodontics

    2024  

    Abstract: Introduction: Determination of the glide path is recommended before using rotary instruments. This study aimed to evaluate the dynamic cyclic fatigue resistance of new and used glider rotary instruments in up to 6 root canals.: Methods: Seventy-two ... ...

    Abstract Introduction: Determination of the glide path is recommended before using rotary instruments. This study aimed to evaluate the dynamic cyclic fatigue resistance of new and used glider rotary instruments in up to 6 root canals.
    Methods: Seventy-two TruNatomy Glider files were used for the preparation of root canals of extracted lower molars, which were then submitted to the dynamic cyclic fatigue test carried out in a curved metallic artificial canal. The instruments were divided into 4 groups (n = 18): Control group, new instruments without any use in the root canal; Group 2U, instruments used in 2 mesial canals; Group 4U, instruments used in 4 mesial canals; Group 6U, instruments used in 6 mesial canals. The time to failure (TF) of the instrument was recorded, and the number of cycles to failure (NCF) was calculated. The data were submitted to 1-way analysis of variance and to the Games-Howell test for multiple comparisons, adopting a significance level of 5%.
    Results: TF and NCF were significantly affected by the number of file uses. The Games-Howell test revealed that TF and NCF were significantly greater in the control group than in Group 4U. In Group 2U, TF and NCF were intermediate and not significantly different from the control group. Group 6U had significantly lower TF and NCF than all other groups.
    Conclusion: The TruNatomy Glider can be used as a glide path for up to 2 mesial canals of mandibular molars, whereas its use on 4 or 6 root canals is not suggested.
    Language English
    Publishing date 2024-02-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 752412-2
    ISSN 1878-3554 ; 0099-2399
    ISSN (online) 1878-3554
    ISSN 0099-2399
    DOI 10.1016/j.joen.2024.01.021
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  10. Article ; Online: Assessment of the impact of conservation measures by modeling soil loss in Minas Gerais, Brazil.

    Soares, A K M / Crestana, S / Ferreira, R R M / Rodrigues, V G S

    Environmental monitoring and assessment

    2024  Volume 196, Issue 4, Page(s) 358

    Abstract: Gullies are significant contributors to soil degradation in several regions of Brazil, including Minas Gerais, where erosion processes have caused soil loss. The characterization of erosion processes is crucial for the application of measures for ... ...

    Abstract Gullies are significant contributors to soil degradation in several regions of Brazil, including Minas Gerais, where erosion processes have caused soil loss. The characterization of erosion processes is crucial for the application of measures for recovering degraded areas and reducing erosion impacts. This study models soil loss with the use of InVEST software and assesses the impact of three different scenarios, namely (1) implementation of soil conservation practices and replacement of pasture areas for temporary agriculture, (2) reforestation of pasture areas, and (3) preservation of ciliary forests. Soil loss, sediment exportation, retention, and deposition for the present scenario (2019), as well as the three aforementioned hypothetical scenarios, were estimated. In the present scenario, the estimated mean annual soil loss was 2.75 t/ha year, with 1,449.54 t/year sediment exportation, 9,042.13 t/year retention, and 1,449.54 t/year deposition. The model predicted scenario 1 would result in 2.23 t/ha year mean annual soil loss, 1,300.59 t/year sediment exportation, 9,191.08 t/year retention, and 11,755.76 t/year deposition. Scenario 2 showed 1.92 t/ha year mean annual soil loss, 1,046.69 t/year sediment exportation, 9,444.98 t/year retention, and 10,229.77 t/year deposition, whereas the results for scenario 3 were 2.36 t/ha year, 616.65 t/year, 9,862.06 t/year, and 13,206.47 t/year, respectively. Reforestation and preservation of ciliary forests, along with soil conservation practices, were effective measures for reducing soil loss. Such findings are valuable for the management of areas degraded by erosion processes.
    MeSH term(s) Soil ; Brazil ; Conservation of Natural Resources/methods ; Environmental Monitoring/methods ; Agriculture/methods
    Chemical Substances Soil
    Language English
    Publishing date 2024-03-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 782621-7
    ISSN 1573-2959 ; 0167-6369
    ISSN (online) 1573-2959
    ISSN 0167-6369
    DOI 10.1007/s10661-024-12509-1
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