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  1. Article: Mentha rotundifolia

    Boualam, Khadija / Ibork, Hind / Lahboub, Zakaria / Sobeh, Mansour / Taghzouti, Khalid

    Frontiers in aging neuroscience

    2024  Volume 16, Page(s) 1365086

    Abstract: Introduction: Aging is often linked to oxidative stress, where the body experiences increased damage from free radicals. Plants are rich sources of antioxidants, playing a role in slowing down aging and supporting the proper functioning and longevity of ...

    Abstract Introduction: Aging is often linked to oxidative stress, where the body experiences increased damage from free radicals. Plants are rich sources of antioxidants, playing a role in slowing down aging and supporting the proper functioning and longevity of cells. Our study focuses on exploring the impact of
    Methods: The chemical composition of MR and SO hydrosols was analyzed by gas chromatography coupled to mass spectrometry. 2,2-Diphenyl 1-picrylhydrazyl and 2,20-azino-bis 3-ethylbenzothiazoline-6-sulfonic acid radicals scavenging assays were used to assess their
    Results and discussion: At two years old, animals treated with MR and SO hydrosols displayed fewer physical and behavioral impairments, along with well-preserved redox homeostasis in comparison with animals in the control group. These results highlighted the significance of MR and SO hydrosols in addressing various aspects of age-related comorbidities. The study suggests that these plant-derived hydrosols may have potential applications in promoting healthy aging and mitigating associated health challenges.
    Language English
    Publishing date 2024-02-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2558898-9
    ISSN 1663-4365
    ISSN 1663-4365
    DOI 10.3389/fnagi.2024.1365086
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  2. Article: Tanacetum

    Khatib, Sohaib / Sobeh, Mansour / Faraloni, Cecilia / Bouissane, Latifa

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1169629

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2023-04-20
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1169629
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Tetraclinis articulata

    Khatib, Sohaib / Mahdi, Ismail / Drissi, Badreddine / Fahsi, Nidal / Bouissane, Latifa / Sobeh, Mansour

    Heliyon

    2024  Volume 10, Issue 3, Page(s) e24563

    Abstract: Type 2 diabetes mellitus (T2DM) is a metabolic syndrome known to contribute to impaired wound healing. This condition can be further worsened by excessive melanin production, elastin degradation, and chronic infections at the wound site, potentially ... ...

    Abstract Type 2 diabetes mellitus (T2DM) is a metabolic syndrome known to contribute to impaired wound healing. This condition can be further worsened by excessive melanin production, elastin degradation, and chronic infections at the wound site, potentially leading to melasma and diabetic dermopathy. The purpose of this study was to investigate the phytochemical profile and inhibitory effects of
    Language English
    Publishing date 2024-01-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e24563
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Gingerols and shogaols: A multi-faceted review of their extraction, formulation, and analysis in drugs and biofluids to maximize their nutraceutical and pharmaceutical applications.

    Maghraby, Yasmin R / Labib, Rola M / Sobeh, Mansour / Farag, Mohamed A

    Food chemistry: X

    2023  Volume 20, Page(s) 100947

    Abstract: Gingerols represent the main bioactive compounds in ginger drugs ... ...

    Abstract Gingerols represent the main bioactive compounds in ginger drugs mostly
    Language English
    Publishing date 2023-10-20
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2590-1575
    ISSN (online) 2590-1575
    DOI 10.1016/j.fochx.2023.100947
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  5. Article: Mentha rotundifolia

    Boualam, Khadija / Bouhaddou, Nezha / Sobeh, Mansour / Tabyaoui, Mohamed / Taghzouti, Khalid

    Frontiers in neuroscience

    2023  Volume 17, Page(s) 1121029

    Abstract: Introduction: Oxidative stress plays a causal role in neurodegenerative diseases. The aim of this study is to evaluate the antioxidant and neuroprotective effects of : Methods: The chemical composition of : Results and discussion: The LC-MS/MS ... ...

    Abstract Introduction: Oxidative stress plays a causal role in neurodegenerative diseases. The aim of this study is to evaluate the antioxidant and neuroprotective effects of
    Methods: The chemical composition of
    Results and discussion: The LC-MS/MS analysis revealed high content of kaempferol glucuronide (85%) at the extract. IC
    Language English
    Publishing date 2023-03-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2411902-7
    ISSN 1662-453X ; 1662-4548
    ISSN (online) 1662-453X
    ISSN 1662-4548
    DOI 10.3389/fnins.2023.1121029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Antibiotic resistance in plant growth promoting bacteria: A comprehensive review and future perspectives to mitigate potential gene invasion risks.

    Mahdi, Ismail / Fahsi, Nidal / Hijri, Mohamed / Sobeh, Mansour

    Frontiers in microbiology

    2022  Volume 13, Page(s) 999988

    Abstract: Plant growth-promoting bacteria (PGPB) are endowed with several attributes that can be beneficial for host plants. They opened myriad doors toward green technology approach to reduce the use of chemical inputs, improve soil fertility, and promote plants' ...

    Abstract Plant growth-promoting bacteria (PGPB) are endowed with several attributes that can be beneficial for host plants. They opened myriad doors toward green technology approach to reduce the use of chemical inputs, improve soil fertility, and promote plants' health. However, many of these PGPB harbor antibiotic resistance genes (ARGs). Less attention has been given to multi-resistant bacterial bioinoculants which may transfer their ARGs to native soil microbial communities and other environmental reservoirs including animals, waters, and humans. Therefore, large-scale inoculation of crops by ARGs-harboring bacteria could worsen the evolution and dissemination of antibiotic resistance and aggravate the negative impacts on such ecosystem and ultimately public health. Their introduction into the soil could serve as ARGs invasion which may inter into the food chain. In this review, we underscore the antibiotic resistance of plant-associated bacteria, criticize the lack of consideration for this phenomenon in the screening and application processes, and provide some recommendations as well as a regulation framework relating to the development of bacteria-based biofertilizers to aid maximizing their value and applications in crop improvement while reducing the risks of ARGs invasion.
    Language English
    Publishing date 2022-09-20
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2022.999988
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  7. Article ; Online: Dissecting dietary and semisynthetic volatile phenylpropenes: A compile of their distribution, food properties, health effects, metabolism and toxicities.

    Zayed, Ahmed / Sobeh, Mansour / Farag, Mohamed A

    Critical reviews in food science and nutrition

    2022  Volume 63, Issue 32, Page(s) 11105–11124

    Abstract: Phenylpropenes represent a major subclass of plant volatiles, including eugenol, and ( ...

    Abstract Phenylpropenes represent a major subclass of plant volatiles, including eugenol, and (
    MeSH term(s) Eugenol/toxicity ; Eugenol/metabolism ; Allylbenzene Derivatives/metabolism ; Diet ; Fruit/metabolism
    Chemical Substances Eugenol (3T8H1794QW) ; anethole (Q3JEK5DO4K) ; Allylbenzene Derivatives
    Language English
    Publishing date 2022-06-16
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1037504-1
    ISSN 1549-7852 ; 1040-8398
    ISSN (online) 1549-7852
    ISSN 1040-8398
    DOI 10.1080/10408398.2022.2087175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1459: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Tetraclinis articulata

    Khatib, Sohaib / Sobeh, Mansour / Bouissane, Latifa

    Frontiers in pharmacology

    2022  Volume 13, Page(s) 977726

    Abstract: Tetraclinis ... ...

    Abstract Tetraclinis articulata
    Language English
    Publishing date 2022-09-05
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.977726
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  9. Article ; Online: Mexican tea (Dysphania ambrosioides (L.) Mosyakin & Clemants) seeds attenuate tourniquet-induced hind limb ischemia–reperfusion injury by modulating ROS and NLRP3 inflammasome pathways

    Annaz, Hassan / Abdelaal, Shimaa / Mandour, Dalia A. / Mahdi, Ismail / Mahmoud, Mona F. / Sobeh, Mansour

    Journal of Functional Foods. 2023 Sept., v. 108 p.105712-

    2023  

    Abstract: The main pathophysiological mechanisms of hind limb ischemia–reperfusion injury (HLIRI) are increased oxidative stress and inflammation. The present study was designed to characterize the phytocontents of Dysphania ambrosioides (DA) seeds extract via LC- ... ...

    Abstract The main pathophysiological mechanisms of hind limb ischemia–reperfusion injury (HLIRI) are increased oxidative stress and inflammation. The present study was designed to characterize the phytocontents of Dysphania ambrosioides (DA) seeds extract via LC-MS/MS and investigate its effect on left hindlimb IR injury and the underlying mechanisms. Thirty adult rats (n = 6 per group) were divided into five groups: Control group; HLIRI group, HLIRI + DA (100 mg/kg) group, HLIRI + DA (200 mg/kg) group, and HLIRI + cilostazol (30 mg/kg) group. HE staining’s of the left gastrocnemius muscle and left kidney was done. Renal function, and both total and muscle creatine kinases were measured in serum. Oxidative stress markers (MDA, SOD, Nrf2 and HO-1), inflammatory markers (NLRP3, IL-1β and TNF-α) and caspase-3 as an apoptotic marker were measured in left gastrocnemius muscle. We found that DA extract contains 60 metabolites and its pretreatment prevented left kidney and left gastrocnemius muscle damage and decreased oxidative stress markers, inflammatory markers, and caspase-3 levels, compared to the control group. Moreover, the effect of the extract was dose-dependent and better than that of the reference drug, cilostazol. This study suggested that D. ambrosioides seeds have a protective effect on HLIRI, which may be related to the antioxidant, anti-inflammatory and antiapoptotic mechanisms.
    Keywords Dysphania ambrosioides ; adults ; antioxidants ; apoptosis ; blood serum ; caspase-3 ; creatine ; dose response ; drugs ; hindlimbs ; inflammasomes ; inflammation ; kidneys ; metabolites ; muscles ; oxidative stress ; phosphotransferases (kinases) ; protective effect ; renal function ; tea ; HLIRI ; Gastrocnemius muscle
    Language English
    Dates of publication 2023-09
    Publishing place Elsevier Ltd
    Document type Article ; Online
    ZDB-ID 2511964-3
    ISSN 1756-4646
    ISSN 1756-4646
    DOI 10.1016/j.jff.2023.105712
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 7830: Show issues

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  10. Article ; Online: Ipomoea carnea mitigates ethanol-induced ulcers in irradiated rats via Nrf2/HO

    Ghareeb, Mosad A / Mohammed, Hala Sh / Aboushousha, Tarek / Lotfy, Dina M / El-Shazly, Maha A M / Sobeh, Mansour / Taha, Eman F S

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 3469

    Abstract: The aim of this study was to investigate the potential of Ipomoea carnea flower methanolic extract (ICME) as a natural gastroprotective therapy against ethanol-induced gastric ulcers, particularly in individuals exposed to ionizing radiation (IR). The ... ...

    Abstract The aim of this study was to investigate the potential of Ipomoea carnea flower methanolic extract (ICME) as a natural gastroprotective therapy against ethanol-induced gastric ulcers, particularly in individuals exposed to ionizing radiation (IR). The study focused on the Nrf2/HO
    MeSH term(s) Animals ; Rats ; Antioxidants/pharmacology ; Ethanol/chemistry ; Gastric Mucosa/metabolism ; Methanol/chemistry ; NF-E2-Related Factor 2/metabolism ; Plant Extracts/chemistry ; Plant Extracts/therapeutic use ; Rats, Wistar ; Stomach Ulcer/drug therapy ; Stomach Ulcer/etiology ; Stomach Ulcer/prevention & control ; Tandem Mass Spectrometry ; Ulcer/pathology
    Chemical Substances Antioxidants ; Ethanol (3K9958V90M) ; Methanol (Y4S76JWI15) ; NF-E2-Related Factor 2 ; Plant Extracts
    Language English
    Publishing date 2024-02-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-53336-1
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