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  1. Article ; Online: Nosocomial COVID-19 on a green ward.

    Soe, Win Mar / Balakrishnan, Aswathi / Adhiyaman, Vedamurthy

    Clinical medicine (London, England)

    2020  Volume 20, Issue 6, Page(s) e282

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Cross Infection/epidemiology ; Hospitals, General ; Humans ; Neurology ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2 ; Stroke ; United Kingdom
    Keywords covid19
    Language English
    Publishing date 2020-11-13
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2048646-7
    ISSN 1473-4893 ; 1470-2118
    ISSN (online) 1473-4893
    ISSN 1470-2118
    DOI 10.7861/clinmed.Let.20.6.8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5439: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: What type of stroke do people on direct oral anticoagulants suffer?

    Thomas, Helen / Soe, Win Mar / Adhiyaman, Vedamurthy / Chattopadhyay, Indrajit

    The journal of the Royal College of Physicians of Edinburgh

    2021  Volume 51, Issue 2, Page(s) 199–207

    MeSH term(s) Administration, Oral ; Anticoagulants/adverse effects ; Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Humans ; Stroke/drug therapy ; Stroke/prevention & control
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2021-07-20
    Publishing country Scotland
    Document type Letter
    ZDB-ID 2866363-9
    ISSN 2042-8189 ; 0953-0932
    ISSN (online) 2042-8189
    ISSN 0953-0932
    DOI 10.4997/JRCPE.2021.228
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3088 -Suppl.-: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Dominant Negative TRAF3 Variant With Recurrent

    Liew, Mei Fong / Lim, Hui Fang / Liang, Mui Cheng / Lim, Ives / Tan, Zhaohong / Tan, Rachel Ying Min / Sam, Qi Hui / Soe, Win Mar / Tay, Sen Hee / Xu, Shengli / Chang, Matthew Wook / Foo, Roger / Soong, Tuck Wah / Ravikumar, Sharada / Chai, Louis Yi Ann

    Open forum infectious diseases

    2022  Volume 9, Issue 8, Page(s) ofac379

    Abstract: Host factors leading to pulmonary nontuberculous mycobacteria (PNTM) disease are poorly understood compared with disseminated NTM disease, which is linked to the interleukin 12-interferon gamma signaling pathway. We investigated the tumor necrosis factor ...

    Abstract Host factors leading to pulmonary nontuberculous mycobacteria (PNTM) disease are poorly understood compared with disseminated NTM disease, which is linked to the interleukin 12-interferon gamma signaling pathway. We investigated the tumor necrosis factor receptor associated factor 3 (TRAF3) R338W variant in a patient with recurrent PNTM infection, demonstrating TRAF3- and TNF-α-deficient phenotypes via ex vivo immune and cloning-transfection cellular studies.
    Language English
    Publishing date 2022-08-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofac379
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A Novel X-Linked Inhibitor of Apoptosis Deficient Variant Showing Attenuated Epstein-Barr Virus Response.

    Zhong, Youjia / Huang, Chiung-Hui / Soe, Win Mar / Chan, Koon Wing / Isa, Mas Suhaila / Soh, Jianyi / Yap, Mark / MacAry, Paul Anthony / Lau, Yu-Lung / Chai, Louis Yi Ann / Shek, Lynette Pei-Chi / Lee, Bee Wah

    Journal of the Pediatric Infectious Diseases Society

    2020  Volume 10, Issue 3, Page(s) 345–348

    Abstract: We report on 2 Asian siblings with X-linked inhibitor of apoptosis deficiency that arose from a novel deletion that presented with Epstein-Barr virus disease and hemophagocytic lymphohistiocytosis. This disease is ascribed to dysfunction in the ... ...

    Abstract We report on 2 Asian siblings with X-linked inhibitor of apoptosis deficiency that arose from a novel deletion that presented with Epstein-Barr virus disease and hemophagocytic lymphohistiocytosis. This disease is ascribed to dysfunction in the nucleotide binding and oligomerization domain receptor pathway, tested using a modified muramyl dipeptide-mediated assay.
    MeSH term(s) Apoptosis ; Epstein-Barr Virus Infections ; Herpesvirus 4, Human/genetics ; Humans ; Lymphohistiocytosis, Hemophagocytic ; Lymphoproliferative Disorders
    Language English
    Publishing date 2020-05-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2668791-4
    ISSN 2048-7207 ; 2048-7193
    ISSN (online) 2048-7207
    ISSN 2048-7193
    DOI 10.1093/jpids/piaa048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Using Expanded Natural Killer Cells as Therapy for Invasive Aspergillosis.

    Soe, Win Mar / Lim, Joan Hui Juan / Williams, David L / Goh, Jessamine Geraldine / Tan, Zhaohong / Sam, Qi Hui / Chotirmall, Sanjay H / Ali, Nur A'tikah Binte Mohamed / Lee, Soo Chin / Seet, Ju Ee / Ravikumar, Sharada / Chai, Louis Yi Ann

    Journal of fungi (Basel, Switzerland)

    2020  Volume 6, Issue 4

    Abstract: Invasive aspergillosis (IA) is a major opportunistic fungal infection in patients with haematological malignancies. Morbidity and mortality rates are high despite anti-fungal treatment, as the compromised status of immune system prevents the host from ... ...

    Abstract Invasive aspergillosis (IA) is a major opportunistic fungal infection in patients with haematological malignancies. Morbidity and mortality rates are high despite anti-fungal treatment, as the compromised status of immune system prevents the host from responding optimally to conventional therapy. This raises the consideration for immunotherapy as an adjunctive treatment. In this study, we evaluated the utility of expanded human NK cells as treatment against
    Language English
    Publishing date 2020-10-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof6040231
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: In vitro drug interactions of gallates with antibiotics in Staphylococcus Aureus.

    Soe, Win Mar / Tzer Pin Lin, Raymond / Chu Sing Lim, Lim / Sakharkar, Kishore R / Sakharkar, Meena K

    Frontiers in bioscience (Elite edition)

    2010  Volume 2, Issue 2, Page(s) 668–672

    Abstract: The antimicrobial activities of tetracycline, mupirocin, and fusidic acid are tested in combination with Epicatechin Gallate (ECG), and Ethyl Gallate (EG) using 2 Methicillin resistant (MRSA) and 2 Methicillin sensitive (MSSA) strains of Staphylococcus ... ...

    Abstract The antimicrobial activities of tetracycline, mupirocin, and fusidic acid are tested in combination with Epicatechin Gallate (ECG), and Ethyl Gallate (EG) using 2 Methicillin resistant (MRSA) and 2 Methicillin sensitive (MSSA) strains of Staphylococcus aureus. Sub-inhibitory concentration of EG at 256 mg l-1 is found to be synergistic when used in combination with tetracycline, mupirocin, and fusidic acid; and a sub-inhibitory concentration of ECG at 32 mg l-1 is found to be synergistic with tetracycline in all the four Staphylococcus aureus strains tested. The synergistic combinations reduce the MICs of all the above three antibiotics by 4 fold. Combining ECG at 32 mg l-1 with mupirocin, reduces the MIC of mupirocin by four fold in MSSA C1 strain. 74 per cent of the combinations show consistent results in both time-kill assay and checkerboard method. The identified combinations may lead towards novel therapeutic interventions for treating MRSA infections.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Catechin/analogs & derivatives ; Catechin/pharmacology ; Drug Interactions/physiology ; Fusidic Acid ; Gallic Acid/analogs & derivatives ; Gallic Acid/pharmacology ; In Vitro Techniques ; Methicillin-Resistant Staphylococcus aureus/drug effects ; Methicillin-Resistant Staphylococcus aureus/metabolism ; Microbial Sensitivity Tests ; Mupirocin ; Tetracycline
    Chemical Substances Anti-Bacterial Agents ; ethyl gallate (235I6UDD3L) ; Fusidic Acid (59XE10C19C) ; Gallic Acid (632XD903SP) ; Catechin (8R1V1STN48) ; epicatechin gallate (92587OVD8Z) ; Mupirocin (D0GX863OA5) ; Tetracycline (F8VB5M810T)
    Language English
    Publishing date 2010-01-01
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2565080-4
    ISSN 1945-0508 ; 1945-0494
    ISSN (online) 1945-0508
    ISSN 1945-0494
    DOI 10.2741/e126
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6871: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: In vitro combinations of antibiotics and phytochemicals against Pseudomonas aeruginosa.

    Sakharkar, Meena K / Jayaraman, Premkumar / Soe, Win Mar / Chow, Vincent T K / Sing, Lim Chu / Sakharkar, Kishore R

    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi

    2009  Volume 42, Issue 5, Page(s) 364–370

    Abstract: Background and purpose: Antibiotic combinations are used to enhance antibacterial efficacy and to prevent the development of resistance. In this study, the in vitro activities of antibiotic and phytochemical combinations against Pseudomonas aeruginosa ... ...

    Abstract Background and purpose: Antibiotic combinations are used to enhance antibacterial efficacy and to prevent the development of resistance. In this study, the in vitro activities of antibiotic and phytochemical combinations against Pseudomonas aeruginosa were tested by the fractional inhibitory concentration method, derived from the minimal inhibitory concentrations (MICs) of the agents in combination.
    Methods: The antimicrobial activity of phytochemicals, alone and in combination with antibiotics, was evaluated using the checkerboard assay and time-kill curve methods.
    Results: There was synergism between gentamicin and caffeic acid, and sulfadiazine and the 3 phytochemicals under investigation (protocatechuic acid, quercetin, caffeic acid). The MIC of sulfadiazine was 256 microg/mL, and of gentamicin was 2 microg/mL. When gentamicin was combined with one-quarter the MIC of caffeic acid, the MIC of gentamicin was reduced 4-fold. When sulfadiazine was tested with one-quarter the MIC of protocatechuic acid, quercetin, and caffeic acid, the MIC was reduced 4-fold in combination with each of the drugs.
    Conclusions: These results indicate the potential efficacy of phytochemicals in combination with antibiotics for enhancing total biological activity.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Caffeic Acids/pharmacology ; Drug Interactions ; Hydroxybenzoates/pharmacology ; Microbial Sensitivity Tests ; Plant Extracts/pharmacology ; Pseudomonas aeruginosa/drug effects ; Quercetin/pharmacology
    Chemical Substances Anti-Bacterial Agents ; Caffeic Acids ; Hydroxybenzoates ; Plant Extracts ; protocatechuic acid (36R5QJ8L4B) ; Quercetin (9IKM0I5T1E) ; caffeic acid (U2S3A33KVM)
    Language English
    Publishing date 2009-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1497590-7
    ISSN 1995-9133 ; 1684-1182 ; 0253-2662
    ISSN (online) 1995-9133
    ISSN 1684-1182 ; 0253-2662
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2083: Show issues Location:
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