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  1. Article ; Online: FASTING-MIMICKING DIET a clarion call for human nutrition research or an additional swan song for a commercial diet?

    Sofi, Francesco

    International journal of food sciences and nutrition

    2020  Volume 71, Issue 8, Page(s) 921–928

    Abstract: Numerous studies have reported beneficial effects for fasting in cellular and animal models, but human studies have shown conflicting results. Recently, a new diet has been introduced both in the scientific literature and in the lay media, the so-called ... ...

    Abstract Numerous studies have reported beneficial effects for fasting in cellular and animal models, but human studies have shown conflicting results. Recently, a new diet has been introduced both in the scientific literature and in the lay media, the so-called fasting-mimicking diet. It is mainly characterised by a diet period that imitates fasting (generally 4-5 consecutive days) consisting of low or very low-calorie intake with a low or very low contribution of carbohydrates and proteins and a high fat intake. This protocol has been tested in some experimental animal models that have studied different outcomes, and in two small clinical trials that have reported some alleged beneficial effects especially on cardio-metabolic risk parameters. However, these clinical trials suffer from many limitations that require attention. The purpose of the present paper is to review the experimental and clinical studies that have investigated this particular dietary approach and to critically discuss the results.
    Language English
    Publishing date 2020-03-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 1121877-0
    ISSN 1465-3478 ; 0963-7486
    ISSN (online) 1465-3478
    ISSN 0963-7486
    DOI 10.1080/09637486.2020.1746959
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3864: Show issues Location:
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  2. Article: FASTING-MIMICKING DIET a clarion call for human nutrition research or an additional swan song for a commercial diet?

    Sofi, Francesco

    International journal of food sciences and nutrition. 2020 Nov. 16, v. 71, no. 8

    2020  

    Abstract: Numerous studies have reported beneficial effects for fasting in cellular and animal models, but human studies have shown conflicting results. Recently, a new diet has been introduced both in the scientific literature and in the lay media, the so-called ... ...

    Abstract Numerous studies have reported beneficial effects for fasting in cellular and animal models, but human studies have shown conflicting results. Recently, a new diet has been introduced both in the scientific literature and in the lay media, the so-called fasting-mimicking diet. It is mainly characterised by a diet period that imitates fasting (generally 4–5 consecutive days) consisting of low or very low-calorie intake with a low or very low contribution of carbohydrates and proteins and a high fat intake. This protocol has been tested in some experimental animal models that have studied different outcomes, and in two small clinical trials that have reported some alleged beneficial effects especially on cardio-metabolic risk parameters. However, these clinical trials suffer from many limitations that require attention. The purpose of the present paper is to review the experimental and clinical studies that have investigated this particular dietary approach and to critically discuss the results.
    Keywords diet ; fat intake ; human nutrition ; humans ; laboratory animals ; nutrition research ; risk ; swans
    Language English
    Dates of publication 2020-1116
    Size p. 921-928.
    Publishing place Taylor & Francis
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 1121877-0
    ISSN 1465-3478 ; 0963-7486
    ISSN (online) 1465-3478
    ISSN 0963-7486
    DOI 10.1080/09637486.2020.1746959
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  3. Article: Editorial: Analyzing the Relationship Between Dietary Patterns, Health Outcomes, and Individual Food Choices.

    Visioli, Francesco / Sofi, Francesco

    Frontiers in nutrition

    2022  Volume 9, Page(s) 840554

    Language English
    Publishing date 2022-02-01
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2022.840554
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Knowledge, attitude and behaviours towards food sustainability in a group of Italian consumers. A cross-sectional study.

    Gianfredi, Vincenza / Stacchini, Lorenzo / Lotti, Sofia / Sarno, Iris / Sofi, Francesco / Dinu, Monica

    International journal of food sciences and nutrition

    2024  , Page(s) 1–12

    Abstract: Sustainability is crucial for transforming the food system, addressing environmental and nutrition issues and depends on consumer perceptions and values. This cross-sectional study investigates the relationship between sustainability attitudes, knowledge, ...

    Abstract Sustainability is crucial for transforming the food system, addressing environmental and nutrition issues and depends on consumer perceptions and values. This cross-sectional study investigates the relationship between sustainability attitudes, knowledge, and eating behaviours. Nearly half reported high level of knowledge regarding food sustainability while 24% expressed high attitude towards food sustainability. Women reported higher levels of knowledge and attitude towards food sustainability. Logistic regression analyses, adjusted for age, sex, and education, revealed that using public transport, biking, or walking was significantly associated with higher odds of having a more positive overall attitude towards food sustainability (OR = 1.77). The overall knowledge score was a strong predictor of a positive overall attitude score (OR = 2.11). Examining individual knowledge-related items, almost all were associated with higher levels of knowledge, except those regarding food and environment interaction. These findings underline a complex scenario where consumers' awareness and knowledge highly influence the applicability of sustainable food choices.
    Language English
    Publishing date 2024-04-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 1121877-0
    ISSN 1465-3478 ; 0963-7486
    ISSN (online) 1465-3478
    ISSN 0963-7486
    DOI 10.1080/09637486.2024.2335524
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3864: Show issues Location:
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  5. Article: Editorial: Ancient crop varieties based food intake: impact on nutritional quality, human health and environmental sustainability.

    Simonetti, Emanuela / Dinu, Monica / Sofi, Francesco / Dinelli, Giovanni / Bosi, Sara

    Frontiers in nutrition

    2023  Volume 10, Page(s) 1211358

    Language English
    Publishing date 2023-06-28
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2023.1211358
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Low-Grade Inflammation and Ultra-Processed Foods Consumption: A Review.

    Tristan Asensi, Marta / Napoletano, Antonia / Sofi, Francesco / Dinu, Monica

    Nutrients

    2023  Volume 15, Issue 6

    Abstract: Low-grade inflammation alters the homeostasis of the organism and favors the onset of many chronic diseases. The global growth in the prevalence of noncommunicable diseases in recent years has been accompanied by an increase in the consumption of ultra- ... ...

    Abstract Low-grade inflammation alters the homeostasis of the organism and favors the onset of many chronic diseases. The global growth in the prevalence of noncommunicable diseases in recent years has been accompanied by an increase in the consumption of ultra-processed foods (UPF). Known to be hyperpalatable, economic and ready-to-eat, increased consumption of UPF has already been recognized as a risk factor for several chronic diseases. Different research groups have tried to investigate whether UPF consumption could promote low-grade inflammation and thus favor the development of noncommunicable diseases. Current evidence highlights the adverse health effects of UPF characteristics, not only due to the nutrients provided by a diet rich in UPF, but also due to the non-nutritive components present in UPF and the effect they may have on gut health. This review aims to summarize the available evidence on the possible relationship between excessive UPF consumption and modulation of low-grade inflammation, as potential promoters of chronic disease.
    MeSH term(s) Humans ; Food, Processed ; Noncommunicable Diseases ; Food Handling ; Fast Foods/adverse effects ; Diet/adverse effects ; Inflammation/epidemiology ; Inflammation/etiology
    Language English
    Publishing date 2023-03-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15061546
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Circadian rhythms, gut microbiota, and diet: Possible implications for health.

    Lotti, Sofia / Dinu, Monica / Colombini, Barbara / Amedei, Amedeo / Sofi, Francesco

    Nutrition, metabolism, and cardiovascular diseases : NMCD

    2023  Volume 33, Issue 8, Page(s) 1490–1500

    Abstract: Aims: Over the past years, interest in chrono-nutrition has grown enormously as the fundamental role of circadian rhythms in regulating most physiological and metabolic processes has become clearer. Recently, the influence of circadian rhythms on the ... ...

    Abstract Aims: Over the past years, interest in chrono-nutrition has grown enormously as the fundamental role of circadian rhythms in regulating most physiological and metabolic processes has become clearer. Recently, the influence of circadian rhythms on the gut microbiota (GM) composition has also emerged, as more than half of the total microbial composition fluctuates rhythmically throughout the day. At the same time, other studies have observed that the GM itself synchronises the host's circadian biological clock through signals of a different nature. Therefore, it has been hypothesised that there is a two-way communication between the circadian rhythms of the host and the GM, but researchers have only just begun to identify some of its action mechanisms. The manuscript aim is, therefore, to gather and combine the latest evidence in the field of chrono-nutrition with the more recent research on the GM, in order to investigate their relationship and their potential impact on human health.
    Data synthesis: Considering current evidence, a desynchronization of circadian rhythms is closely associated with an alteration in the abundance and functionality of the gut microbiota with consequent deleterious effects on health, such as increased risk of numerous pathologies, including cardiovascular disease, cancer, irritable bowel disease, and depression. A key role in maintaining the balance between circadian rhythms and GM seems to be attributed to meal-timing and diet quality, as well as to certain microbial metabolites, in particular short-chain fatty acids.
    Conclusions: Future studies are needed to decipher the link between the circadian rhythms and specific microbial patterns in relation to different disease frameworks.
    MeSH term(s) Humans ; Gastrointestinal Microbiome ; Circadian Rhythm/physiology ; Diet/adverse effects ; Neoplasms ; Nutritional Status
    Language English
    Publishing date 2023-05-14
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1067704-5
    ISSN 1590-3729 ; 0939-4753
    ISSN (online) 1590-3729
    ISSN 0939-4753
    DOI 10.1016/j.numecd.2023.05.009
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3149: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  8. Article: Editorial: Insights in nutritional epidemiology.

    Serafini, Mauro / Sofi, Francesco / McCrory, Megan A

    Frontiers in nutrition

    2022  Volume 9, Page(s) 1032825

    Language English
    Publishing date 2022-09-27
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2022.1032825
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Circadian rhythms, gut microbiota, and diet: Possible implications for health

    Lotti, Sofia / Dinu, Monica / Colombini, Barbara / Amedei, Amedeo / Sofi, Francesco

    The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University Nutrition, Metabolism and Cardiovascular Diseases. 2023 May 14,

    2023  

    Abstract: Over the past years, interest in chrono-nutrition has grown enormously as the fundamental role of circadian rhythms in regulating most physiological and metabolic processes has become clearer. Recently, the influence of circadian rhythms on the gut ... ...

    Abstract Over the past years, interest in chrono-nutrition has grown enormously as the fundamental role of circadian rhythms in regulating most physiological and metabolic processes has become clearer. Recently, the influence of circadian rhythms on the gut microbiota (GM) composition has also emerged, as more than half of the total microbial composition fluctuates rhythmically throughout the day. At the same time, other studies have observed that the GM itself synchronises the host's circadian biological clock through signals of a different nature. Therefore, it has been hypothesised that there is a two-way communication between the circadian rhythms of the host and the GM, but researchers have only just begun to identify some of its action mechanisms. The manuscript aim is, therefore, to gather and combine the latest evidence in the field of chrono-nutrition with the more recent research on the GM, in order to investigate their relationship and their potential impact on human health. Considering current evidence, a desynchronization of circadian rhythms is closely associated with an alteration in the abundance and functionality of the gut microbiota with consequent deleterious effects on health, such as increased risk of numerous pathologies, including cardiovascular disease, cancer, irritable bowel disease, and depression. A key role in maintaining the balance between circadian rhythms and GM seems to be attributed to meal-timing and diet quality, as well as to certain microbial metabolites, in particular short-chain fatty acids. Future studies are needed to decipher the link between the circadian rhythms and specific microbial patterns in relation to different disease frameworks.
    Keywords biological clocks ; cardiovascular diseases ; diet ; eating habits ; food quality ; human health ; intestinal microorganisms ; metabolism ; metabolites ; risk ; Chrono-nutrition ; Chronotype ; Microbiome ; Dietary habits ; Health status
    Language English
    Dates of publication 2023-0514
    Publishing place Elsevier B.V.
    Document type Article ; Online
    Note Pre-press version
    ZDB-ID 1067704-5
    ISSN 0939-4753
    ISSN 0939-4753
    DOI 10.1016/j.numecd.2023.05.009
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Cologne/Königswinter

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  10. Article ; Online: Microbiome in Behcet's syndrome.

    Bettiol, Alessandra / Emmi, Giacomo / Low, Liying / Sofi, Francesco / Wallace, Graham R

    Clinical immunology (Orlando, Fla.)

    2023  Volume 250, Page(s) 109304

    Abstract: This review will discuss the current understanding of the role of microbiomes in Behcet's Syndrome, their influence on immune response and disease and potential future studies. ...

    Abstract This review will discuss the current understanding of the role of microbiomes in Behcet's Syndrome, their influence on immune response and disease and potential future studies.
    MeSH term(s) Humans ; Behcet Syndrome ; Immunity ; Microbiota
    Language English
    Publishing date 2023-03-30
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1459903-x
    ISSN 1521-7035 ; 1521-6616
    ISSN (online) 1521-7035
    ISSN 1521-6616
    DOI 10.1016/j.clim.2023.109304
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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