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  1. AU="Solá-Sánchez, Ernesto"
  2. AU="Cinquanta, Lucrezia"
  3. AU="Drivenes, Jakob Lillemoen"
  4. AU="Martín, José Ignacio Valero"
  5. AU=Mahmood Shah Sayed Mustafa
  6. AU=Sales-Peres Silvia Helena de Carvalho
  7. AU="Boyea, Beth Lincoln"
  8. AU=Martorell-Marugan Jordi
  9. AU="Serventi, Lisa"
  10. AU=O'Shea John J AU=O'Shea John J
  11. AU="Jiang, Dahai"
  12. AU="Sheng, Chu-Qiao"
  13. AU="Rodríguez, Fausto J."
  14. AU="Sadowski, Peter"
  15. AU="Noguera, Austin"
  16. AU="Daigneault, Tina"
  17. AU="Flores-Martínez, José Juan"
  18. AU="Gan, Yu-Ling"
  19. AU=Banno Asoka AU=Banno Asoka
  20. AU="Bertolin, Kalyne"
  21. AU="Rising, James A"
  22. AU="Jackson Voelkel"
  23. AU="Arias, Marisa"
  24. AU="Le, Uyen Nguyen Phuong"
  25. AU="Shim, Yun M"
  26. AU="Ngan, Hau Lan"
  27. AU="Shah, Fawad Ali"
  28. AU="Rodriguez Chinesta, J M"
  29. AU="Reddy, Avril"
  30. AU="Vachani, Anil"
  31. AU="Lofland, Gabriela"
  32. AU="Zou, Xiaoyan"
  33. AU="Norhafizah Bt Sahril"

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  1. Artikel: Effect of once weekly oral levothyroxine therapy.

    Toro-Diez, Andrea Del / Solá-Sánchez, Ernesto / Mangual-García, Michelle

    Endocrinology, diabetes & metabolism case reports

    2021  Band 2021

    Abstract: Summary: Primary hypothyroidism is one of the most common endocrine disorders with widely available treatment. A minority of patients remain with uncontrolled hypothyroidism despite therapy. The objective of this case series was to demonstrate that ... ...

    Abstract Summary: Primary hypothyroidism is one of the most common endocrine disorders with widely available treatment. A minority of patients remain with uncontrolled hypothyroidism despite therapy. The objective of this case series was to demonstrate that medication non-adherence, rather than malabsorption, should be sought as the most common cause of unsuppressed TSH levels in patients receiving treatment for this condition. Non-adherence is often considered as a diagnosis of exclusion. Nonetheless, a diagnosis of malabsorption requires a more extensive workup, including imaging and invasive procedures, which increase healthcare costs and burden to the patient. The findings of this study allow for a cost-effective approach to uncontrolled hypothyroidism.
    Learning points: Medication non-adherence is a common cause of insuppressible TSH levels. Once weekly levothyroxine is an alternative approach to non-compliant patients. Assessing compliance is more cost-effective and less burdensome than testing for malabsorption.
    Sprache Englisch
    Erscheinungsdatum 2021-07-01
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2785530-2
    ISSN 2052-0573
    ISSN 2052-0573
    DOI 10.1530/EDM-21-0045
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Lingual thyroid gland: it's time for awareness.

    Cruz-Dardíz, Nicolás / Rivera-Santana, Nadyeschka / Torres-Torres, Marina / Cintrón-Colón, Héctor / Lajud, Shayanne / Solá-Sánchez, Ernesto / Mangual-García, Michelle / González-Bóssolo, Alex

    Endocrinology, diabetes & metabolism case reports

    2020  Band 2020

    Abstract: Summary: Lingual thyroid (LT) gland is the most common type of ectopic thyroid tissue, but it is an extremely rare presentation. We present a case of a 41-year-old Hispanic female patient complaining of dysphonia and dysphagia. As part of the evaluation, ...

    Abstract Summary: Lingual thyroid (LT) gland is the most common type of ectopic thyroid tissue, but it is an extremely rare presentation. We present a case of a 41-year-old Hispanic female patient complaining of dysphonia and dysphagia. As part of the evaluation, fiber optic flexible indirect laryngoscopy (FIL) was performed which revealed a mass at the base of the tongue. The morphological examination was highly suspicious for ectopic thyroid tissue and the diagnosis was confirmed with neck ultrasound and thyroid scintigraphy. Although the patient presented subclinical hypothyroidism, levothyroxine therapy was initiated with a favorable response which included resolution of symptoms and mass size reduction. Our case portrays how thyroid hormone replacement therapy (THRT) may lead to a reduction in the size of the ectopic tissue and improvement of symptoms, thus avoiding the need for surgical intervention which could result in profound hypothyroidism severely affecting the patients' quality of life.
    Learning points: Benign LT and malignant LT are indistinguishable clinically and radiographically for which histopathology is recommended. THRT, radioactive iodine 131 (RAI) therapy, and surgical excision are potential management options for LT. THRT may lead to size reduction of the ectopic tissue and resolution of symptoms avoiding surgical intervention.
    Sprache Englisch
    Erscheinungsdatum 2020-05-29
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2785530-2
    ISSN 2052-0573
    ISSN 2052-0573
    DOI 10.1530/EDM-20-0026
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  3. Artikel: Papillary Thyroid Carcinoma: Ectopic Malignancy versus Metastatic Disease.

    Agosto-Vargas, Yanery's / Gutiérrez, Madeleine / Martínez, José Hernán / Mangual-Garcia, Michelle / Palermo, Coromoto / Vélez-Maymi, Sharon / Hernández-Vázquez, Luis / Miranda-Rodríguez, Samayra / González-Bossolo, Alex / Solá-Sánchez, Ernesto / Hernández-Negrón, Marianne

    Case reports in endocrinology

    2017  Band 2017, Seite(n) 9707031

    Abstract: Papillary thyroid carcinoma frequently metastasizes to regional lymph nodes. However, cervical lymph node metastasis as a sole manifestation of occult papillary thyroid carcinoma is rarely observed. Ectopic thyroid is an uncommon condition defined as the ...

    Abstract Papillary thyroid carcinoma frequently metastasizes to regional lymph nodes. However, cervical lymph node metastasis as a sole manifestation of occult papillary thyroid carcinoma is rarely observed. Ectopic thyroid is an uncommon condition defined as the presence of thyroid tissue at a site other than pretracheal area. Approximately 1-3% of all ectopic thyroid tissue is located in the lateral neck. This entity may represent the only functional thyroid tissue in the body. Malignant transformation of ectopic thyroid is uncommon; but even rarer is the development of papillary carcinoma on it. We present a case of a 33-year-old man with an incidental lateral neck mass diagnosed after a motor vehicle accident. Total thyroidectomy and lymph node resection were completed without evidence of papillary thyroid carcinoma. Malignant transformation of heterotopic thyroid tissue was the final diagnosis. The possibility of an ectopic thyroid cancer should be considered in the differential diagnosis of a pathological mass in the neck. The uniqueness of this case strives in the rarity that the thyroid gland was free of malignancy, despite ectopic tissue being positive for thyroid carcinoma. Management strategies, including performance of total thyroidectomy, neck dissection, and treatment with radioiodine, should be based on individualized risk assessment.
    Sprache Englisch
    Erscheinungsdatum 2017-06-18
    Erscheinungsland United States
    Dokumenttyp Case Reports
    ZDB-ID 2627633-1
    ISSN 2090-651X ; 2090-6501
    ISSN (online) 2090-651X
    ISSN 2090-6501
    DOI 10.1155/2017/9707031
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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