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  1. AU="Song, Jin-Ju"
  2. AU="Liu-Xia Zhang"
  3. AU="Ahmed, Abdallah M Said"
  4. AU=Hover Alexander R
  5. AU="Zaniar Ghazizadeh"
  6. AU="Rathod, Aniruddha"
  7. AU=Ong Edison
  8. AU="Hoffmann, Daniela"
  9. AU="Mallett, Garry"
  10. AU=Lemos Pedro A
  11. AU="Bakris, George L."
  12. AU="Tun-Linn Thein"
  13. AU="Michelle Schinkel"
  14. AU="Scolieri, G"

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  1. Artikel: [Optimization of processing technology of braised Rehmanniae Radix based on multiple indexes and response surface technology and correlation between components and color].

    Xie, Yang / Zhong, Ling-Yun / Xue, Xiao / Wang, Zhuo / Song, Jin-Ju / Li, Jia-Qing / Zhang, Qing / Wang, Yi-Bin / Zeng, Yan

    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

    2022  Band 47, Heft 18, Seite(n) 4927–4937

    Abstract: This study aims to explore the key factors influencing the processing of braised Rehmanniae Radix, optimize the processing, and determine the correlation between the components in different processed products and chroma values, which is expected to add ... ...

    Abstract This study aims to explore the key factors influencing the processing of braised Rehmanniae Radix, optimize the processing, and determine the correlation between the components in different processed products and chroma values, which is expected to add quantitative indexes for the processing of braised Rehmanniae Radix and better control the processing. The weights of the indexes catalpol, rehmannioside D, verbascoside, isoacteoside, 5-hydroxymethylfurfural, reducing sugar, and appearance were calculated based on analytic hierarchy process(AHP) in combination with coefficient of variation, and the overall desirability(OD) was obtained. Box-Behnken design was used to explore the optimal amount of water added, time for soaking with rice wine, and steaming time in the processing of braised Rehmanniae Radix. Colorimeter was employed to determine the chroma of 17 samples and raw samples, and SPSS, Prism, and other software to investigate the correlation between the components in braised Rehmanniae Radix and the chroma values. The results showed that each factor influenced the processing, and the influence followed the order of steaming time>amount of water added>time for soaking with rice wine. The optimal processing process is as below: A total of 100 g medicinal material was added with 7 times of water, followed by soaking with rice wine for 5 h and steaming in a pot for 6 h. The correlation analysis suggested the extremely significantly positive correlation between L~* and content of catalpol, between a~* and 5-hydroxymethylfurfural content, and between b~* and catalpol content, and the extremely significantly negative correlation between L~* and the content of 5-hydroxymethylfurfural and reducing sugar, and between b~* and the content of 5-hydroxymethylfural and reducing sugar. In this experiment, response surface methodology was used to optimize the processing technology of braised Rehmanniae Radix and the optimized process was rational and feasible. The content of chemical components in braised Rehmanniae Radix was significantly correlated with the chroma. This study provided a new method for the quality evaluation of braised Rehmanniae Radix.
    Mesh-Begriff(e) Drugs, Chinese Herbal/chemistry ; Furaldehyde/analogs & derivatives ; Iridoid Glucosides ; Plant Extracts ; Rehmannia/chemistry ; Sugars ; Technology ; Water
    Chemische Substanzen 5-hydroxymethylfurfural (70ETD81LF0) ; catalpol (2415-24-9) ; Drugs, Chinese Herbal ; Furaldehyde (DJ1HGI319P) ; Iridoid Glucosides ; Plant Extracts ; rehmannia root (1BEM3U6LQQ) ; Sugars ; Water (059QF0KO0R)
    Sprache Chinesisch
    Erscheinungsdatum 2022-09-23
    Erscheinungsland China
    Dokumenttyp Journal Article
    ZDB-ID 1004649-5
    ISSN 1001-5302 ; 0254-0029
    ISSN 1001-5302 ; 0254-0029
    DOI 10.19540/j.cnki.cjcmm.20220128.306
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Trace Albumin in the Urine Dipstick Test is Associated with Coronary Artery Calcification in Korean Adults.

    Song, Jin Ju / Lee, Kyu-Beck / Hyun, Young Youl / Kim, Hyang

    Nephron

    2018  Band 140, Heft 3, Seite(n) 169–174

    Abstract: Background/aims: Albuminuria is a risk factor for coronary artery calcification (CAC) and cardiovascular disease (CVD). Although the urine dipstick test is widely used to screen albuminuria, little is known about the association between low-grade urine ... ...

    Abstract Background/aims: Albuminuria is a risk factor for coronary artery calcification (CAC) and cardiovascular disease (CVD). Although the urine dipstick test is widely used to screen albuminuria, little is known about the association between low-grade urine dipstick albumin and CAC. The aim of this study is to investigate the relationship between the trace of urine dipstick albumin and CAC in Korean adults.
    Methods: This cross-sectional study analyzed 45,006 participants without previous CVD, who underwent coronary computed tomography and urine dipstick test from 2012 to 2014 as part of a health examination program in Korea. CAC was defined as coronary artery calcium score > 100. Participants were divided into 3 groups based on urine dipstick albumin results as follows: negative (-), trace (±), and positive (+1 to +4).
    Results: The numbers of participants with CAC were 800 (2.0%), 111 (2.8%), and 33 (4.9%) for the negative, trace, and positive groups respectively. Based on multivariate analysis, albuminuria determined with urine dipstick test was associated with CAC after adjustment for various cardiovascular risk factors. Compared with the negative group, the OR for CAC was 1.62 (1.08-2.42) in the positive group and 1.34 (1.07-1.66) in the trace group.
    Conclusion: Even a trace level of albumin in the urine dipstick test was associated with subclinical CAC in Korean adults. Low-grade dipstick albuminuria should not be overlooked.
    Mesh-Begriff(e) Adult ; Albuminuria/diagnosis ; Albuminuria/urine ; Coronary Vessels/pathology ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Republic of Korea ; Retrospective Studies ; Sensitivity and Specificity ; Urinalysis/methods ; Vascular Calcification/urine
    Sprache Englisch
    Erscheinungsdatum 2018-07-10
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 207121-6
    ISSN 2235-3186 ; 1423-0186 ; 1660-8151 ; 0028-2766
    ISSN (online) 2235-3186 ; 1423-0186
    ISSN 1660-8151 ; 0028-2766
    DOI 10.1159/000490954
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: Trace Albumin in the Urine Dipstick Test is Associated with Coronary Artery Calcification in Korean Adults

    Song, Jin Ju / Lee, Kyu-Beck / Hyun, Young Youl / Kim, Hyang

    Nephron

    2018  Band 140, Heft 3, Seite(n) 169–174

    Abstract: Background/Aims: Albuminuria is a risk factor for coronary artery calcification (CAC) and cardiovascular disease (CVD). Although the urine dipstick test is widely used to screen albuminuria, little is known about the association between low-grade urine ... ...

    Körperschaft Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
    Abstract Background/Aims: Albuminuria is a risk factor for coronary artery calcification (CAC) and cardiovascular disease (CVD). Although the urine dipstick test is widely used to screen albuminuria, little is known about the association between low-grade urine dipstick albumin and CAC. The aim of this study is to investigate the relationship between the trace of urine dipstick albumin and CAC in Korean adults. Methods: This cross-sectional study analyzed 45,006 participants without previous CVD, who underwent coronary computed tomography and urine dipstick test from 2012 to 2014 as part of a health examination program in Korea. CAC was defined as coronary artery calcium score > 100. Participants were divided into 3 groups based on urine dipstick albumin results as follows: negative (–), trace (±), and positive (+1 to +4). Results: The numbers of participants with CAC were 800 (2.0%), 111 (2.8%), and 33 (4.9%) for the negative, trace, and positive groups respectively. Based on multivariate analysis, albuminuria determined with urine dipstick test was associated with CAC after adjustment for various cardiovascular risk factors. Compared with the negative group, the OR for CAC was 1.62 (1.08–2.42) in the positive group and 1.34 (1.07–1.66) in the trace group. Conclusion: Even a trace level of albumin in the urine dipstick test was associated with subclinical CAC in Korean adults. Low-grade dipstick albuminuria should not be overlooked.
    Schlagwörter Urine dipstick test ; Trace ; Albuminuria ; Coronary artery calcification
    Sprache Englisch
    Erscheinungsdatum 2018-07-10
    Verlag S. Karger AG
    Erscheinungsort Basel, Switzerland
    Dokumenttyp Artikel
    Anmerkung Clinical Practice: Original Paper
    ZDB-ID 207121-6
    ISSN 2235-3186 ; 1423-0186 ; 1660-8151 ; 0028-2766
    ISSN (online) 2235-3186 ; 1423-0186
    ISSN 1660-8151 ; 0028-2766
    DOI 10.1159/000490954
    Datenquelle Karger Verlag

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