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  1. Book ; Online: Climate Lyricism

    Hyoung Song, Min

    2021  

    Keywords Literary studies: from c 1900 ; Conservation of the environment ; Ethnic studies ; climate change, lyric, contemporary literature, race, aesthetics
    Language English
    Size 1 electronic resource (257 pages)
    Publisher Duke University Press
    Publishing place Durham
    Document type Book ; Online
    Note English
    HBZ-ID HT030376924
    ISBN 9781478017738 ; 1478017732
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: The Asparaginyl Endopeptidase Legumain: An Emerging Therapeutic Target and Potential Biomarker for Alzheimer's Disease.

    Song, Mingke

    International journal of molecular sciences

    2022  Volume 23, Issue 18

    Abstract: Alzheimer's disease (AD) is incurable dementia closely associated with aging. Most cases of AD are sporadic, and very few are inherited; the pathogenesis of sporadic AD is complex and remains to be elucidated. The asparaginyl endopeptidase (AEP) or ... ...

    Abstract Alzheimer's disease (AD) is incurable dementia closely associated with aging. Most cases of AD are sporadic, and very few are inherited; the pathogenesis of sporadic AD is complex and remains to be elucidated. The asparaginyl endopeptidase (AEP) or legumain is the only recognized cysteine protease that specifically hydrolyzes peptide bonds after asparagine residues in mammals. The expression level of AEPs in healthy brains is far lower than that of peripheral organs. Recently, growing evidence has indicated that aging may upregulate and overactivate brain AEPs. The overactivation of AEPs drives the onset of AD through cleaving tau and amyloid precursor proteins (APP), and SET, an inhibitor of protein phosphatase 2A (PP2A). The AEP-mediated cleavage of these peptides enhances amyloidosis, promotes tau hyperphosphorylation, and ultimately induces neurodegeneration and cognitive impairment. Upregulated AEPs and related deleterious reactions constitute upstream events of amyloid/tau toxicity in the brain, and represent early pathological changes in AD. Thus, upregulated AEPs are an emerging drug target for disease modification and a potential biomarker for predicting preclinical AD. However, the presence of the blood-brain barrier greatly hinders establishing body-fluid-based methods to measure brain AEPs. Research on AEP-activity-based imaging probes and our recent work suggest that the live brain imaging of AEPs could be used to evaluate its predictive efficacy as an AD biomarker. To advance translational research in this area, AEP imaging probes applicable to human brain and AEP inhibitors with good druggability are urgently needed.
    MeSH term(s) Alzheimer Disease/metabolism ; Amyloid beta-Peptides/metabolism ; Animals ; Asparagine/metabolism ; Biomarkers/metabolism ; Brain/metabolism ; Cysteine Endopeptidases/metabolism ; Humans ; Mammals/metabolism ; Protein Phosphatase 2/metabolism ; tau Proteins/genetics ; tau Proteins/metabolism
    Chemical Substances Amyloid beta-Peptides ; Biomarkers ; tau Proteins ; Asparagine (7006-34-0) ; Protein Phosphatase 2 (EC 3.1.3.16) ; Cysteine Endopeptidases (EC 3.4.22.-) ; asparaginylendopeptidase (EC 3.4.22.34)
    Language English
    Publishing date 2022-09-06
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms231810223
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Global epidemiology and prevention of colorectal cancer.

    Song, Mingyang

    The lancet. Gastroenterology & hepatology

    2022  Volume 7, Issue 7, Page(s) 588–590

    MeSH term(s) Colorectal Neoplasms/epidemiology ; Colorectal Neoplasms/prevention & control ; Humans ; Risk Factors
    Language English
    Publishing date 2022-04-07
    Publishing country Netherlands
    Document type Journal Article ; Comment
    ISSN 2468-1253
    ISSN (online) 2468-1253
    DOI 10.1016/S2468-1253(22)00089-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Chinese English as Foreign Language Teachers' Self-Efficacy and Motivation as Predictors of Burnout.

    Song, Meiling

    Frontiers in psychology

    2022  Volume 13, Page(s) 899687

    Abstract: In contemporary education, educators are a central and focal component of academic structures accountable for education growth. Educators have an effective role in presenting and planning an effective and important academic program. However, they usually ...

    Abstract In contemporary education, educators are a central and focal component of academic structures accountable for education growth. Educators have an effective role in presenting and planning an effective and important academic program. However, they usually experience burnout due to their stressful job that affects the procedure of their teaching. So, considering the variables that help them in mitigating their burnout should be taken into account. The concept such as educator efficacy has recently attracted significant attention in education fields which by itself emphasizes educators and gets them into the focus of attention in education. Also, the concept of motivation has a strong relationship with the expert aspect of the educators and its significance for language educators and their students are increasingly gaining respect in various worldwide settings, in which lower educators' motivation is generally a reason for distress. To focus on the predictability role of these constructs on teachers' burnout, 428 female and male Chinese English as Foreign Language (EFL) teachers from more than 17 cities in nine provinces of China were asked to fill out the three scales, namely, teacher motivation, efficacy, and burnout. The main results of the study, achieved through Pearson Correlation, postulate that the relationships exist among the variables of the study, and by running multiple regression analysis, it is revealed that both variables, namely, self-efficacy and motivation, were the predictors of teachers' burnout, while self-efficacy was a better predictor. Regarding the applications, educator training plans can focus more on educator self-efficacy and motivation, because of their proven important role in decreasing educator burnout.
    Language English
    Publishing date 2022-05-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2022.899687
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: IoT Speech Recognition Application in Mass Sports Data Monitoring Based on Dynamic Adaptive Recommendation Algorithm.

    Song, Meng

    Computational intelligence and neuroscience

    2022  Volume 2022, Page(s) 8032571

    Abstract: In this paper, the existing dynamic adaptive recommendation methods are studied, which combine the practical application scheme of transforming the actual dynamic adaptive recommendation problem into user microblog information. After that, a dynamic ... ...

    Abstract In this paper, the existing dynamic adaptive recommendation methods are studied, which combine the practical application scheme of transforming the actual dynamic adaptive recommendation problem into user microblog information. After that, a dynamic adaptive weight fusion method is proposed and based on experimental verification, a real-time dynamic adaptive recommendation system is finally designed. The speech recognition of the Internet of Things takes natural language problems as the research object for a long time and takes the sound signal as the research topic. This paper analyzes the application of dynamic adaptive recommendation and Internet of Things speech recognition in mass sports data monitoring. The simulation results show that the system in this paper is convenient for users to monitor the exercise indicators in real time through the mobile client, and at the same time query the exercise historical data and compare the exercise data through the network terminal, thereby improving the exercise method and exercise load. Users can access the motion monitoring module and see the past floating state of motion parameters more intuitively than graphs, contains queries for metrics such as heart rate, body temperature, kinetic energy, pulse, and weight. Due to the diversity and complexity of people's differences, personal characteristics and business environments, sports data monitoring systems also need to be designed according to the scope of use. This paper analyzes the requirements for a motion data monitoring system and provides the system architecture design and basic data for producing detailed information for the system.
    MeSH term(s) Humans ; Speech Perception ; Algorithms ; Electrocardiography
    Language English
    Publishing date 2022-10-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2388208-6
    ISSN 1687-5273 ; 1687-5273
    ISSN (online) 1687-5273
    ISSN 1687-5273
    DOI 10.1155/2022/8032571
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Influence of a continuous nursing model based on network cloud platforms for urinary control, urination function and quality of life of patients after radical prostatectomy.

    Song, Miaomiao

    American journal of translational research

    2021  Volume 13, Issue 5, Page(s) 5356–5361

    Abstract: Objective: To investigate the effect of a continuous nursing mode on urinary control, urinary function and quality of life of patients after radical prostatectomy under the network cloud platform.: Method: A total of 100 prostate cancer patients ... ...

    Abstract Objective: To investigate the effect of a continuous nursing mode on urinary control, urinary function and quality of life of patients after radical prostatectomy under the network cloud platform.
    Method: A total of 100 prostate cancer patients admitted to our hospital from January 2017 to January 2019 were enrolled. According to different care modes, they were divided into the experimental group and the control group, 50 patients in each group. Patients in the experimental group received the continuous care model under the network cloud platform, and the control group patients received the conventional care model. Urinary control, urination, self-care ability, incidence of complications, quality of life and nursing satisfaction of the two groups were compared.
    Results: In terms of urination, urinary control, quality of life, self-care ability, the incidence of complications and nursing satisfaction, the experimental group was better than the control group (P<0.05).
    Conclusion: The continuous nursing model under the network cloud platform has a positive impact on patient's urinary control, urination function and quality of life after radical prostatectomy. It is worthy of being widely promoted and used in clinical treatment.
    Language English
    Publishing date 2021-05-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2471058-1
    ISSN 1943-8141
    ISSN 1943-8141
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Cancer overtakes vascular disease as leading cause of excess death associated with diabetes.

    Song, Mingyang

    The lancet. Diabetes & endocrinology

    2021  Volume 9, Issue 3, Page(s) 131–133

    MeSH term(s) Cause of Death ; Diabetes Mellitus ; England ; Humans ; Neoplasms/complications ; Primary Health Care ; Vascular Diseases/complications
    Language English
    Publishing date 2021-02-04
    Publishing country England
    Document type Journal Article ; Comment
    ISSN 2213-8595
    ISSN (online) 2213-8595
    DOI 10.1016/S2213-8587(21)00016-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Comment on: Toll-like receptor 4 and MyD88 are required for gastric bypass-induced metabolic effects.

    Song, Ming

    Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery

    2021  Volume 17, Issue 12, Page(s) 2006–2008

    MeSH term(s) Gastric Bypass ; Humans ; Myeloid Differentiation Factor 88/genetics ; Myeloid Differentiation Factor 88/metabolism ; Signal Transduction ; Toll-Like Receptor 4/genetics ; Toll-Like Receptor 4/metabolism
    Chemical Substances Myeloid Differentiation Factor 88 ; Toll-Like Receptor 4
    Language English
    Publishing date 2021-08-30
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2274243-8
    ISSN 1878-7533 ; 1550-7289
    ISSN (online) 1878-7533
    ISSN 1550-7289
    DOI 10.1016/j.soard.2021.08.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6572: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Response to Letter to the Editor by Scarano-Pereira et al.: Response to: Recent advances in the mechanisms underlying the beneficial effects of bariatric and metabolic surgery.

    Song, Ming

    Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery

    2021  Volume 18, Issue 2, Page(s) 298

    MeSH term(s) Bariatric Surgery ; Bariatrics ; Humans
    Language English
    Publishing date 2021-11-11
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2274243-8
    ISSN 1878-7533 ; 1550-7289
    ISSN (online) 1878-7533
    ISSN 1550-7289
    DOI 10.1016/j.soard.2021.11.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Authors' Reply: Interpreting epidemiologic studies of colonoscopy screening for colorectal cancer prevention.

    Song, Mingyang / Bretthauer, Michael

    European journal of epidemiology

    2024  

    Language English
    Publishing date 2024-01-23
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 632614-6
    ISSN 1573-7284 ; 0393-2990
    ISSN (online) 1573-7284
    ISSN 0393-2990
    DOI 10.1007/s10654-023-01077-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2090: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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