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Article ; Online: Reproduced out-of-plane ferroelectricity in monolayer SnTe van der Waals heterostructures.

Song, Wenjing / Cao, Wang / Zhao, Wei / Ding, Jianwen

Journal of physics. Condensed matter : an Institute of Physics journal

2023 Volume 35, Issue 35

Abstract: Due to the shrinking in size of nonvolatile memory devices, the two-dimensional ferroelectric van der Waals (vdW) heterostructures have received huge attention. However, it is still difficult to maintain the out-of-plane (OOP) ferroelectricity. In this ... ...

Abstract	Due to the shrinking in size of nonvolatile memory devices, the two-dimensional ferroelectric van der Waals (vdW) heterostructures have received huge attention. However, it is still difficult to maintain the out-of-plane (OOP) ferroelectricity. In this work, we have theoretically investigated the relationship between the ferroelectricity and the strain of bulk and few-layer SnTe by first-principles calculations. The results indicate that the
Language	English
Publishing date	2023-06-05
Publishing country	England
Document type	Journal Article
ZDB-ID	1472968-4
ISSN	1361-648X ; 0953-8984
ISSN (online)	1361-648X
ISSN	0953-8984
DOI	10.1088/1361-648X/acd906
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Article: Potential mechanisms of exercise for relieving inflammatory pain: a literature review of animal studies.

Wu, Minmin / Song, Wenjing / Zhang, Mei / Teng, Lili / Tang, Qiang / Zhu, Luwen

Frontiers in aging neuroscience

2024 Volume 16, Page(s) 1359455

Abstract: Inflammatory pain (IP) is one of the most prevalent and intractable human conditions, and it leads to progressive dysfunction and reduced quality of life. Additionally, IP is incredibly challenging to treat successfully with drugs or surgery. The ... ...

Abstract	Inflammatory pain (IP) is one of the most prevalent and intractable human conditions, and it leads to progressive dysfunction and reduced quality of life. Additionally, IP is incredibly challenging to treat successfully with drugs or surgery. The development of IP is complex and multifactorial, and peripheral and central sensitization may influence chronicity and treatment resistance in IP. Understanding the mechanisms underlying IP is vital for developing novel therapies. Strong evidence suggests that exercise can be a first-line relief for patients with IP during rehabilitation. However, the mechanisms through which exercise improves IP remain unclear. Here, we reviewed the current animal experimental evidence for an exercise intervention in IP and proposed biological mechanisms for the effects of synaptic plasticity in the anterior cingulate cortex, endocannabinoids, spinal dorsal horn excitability balance, immune cell polarization balance, cytokines, and glial cells. This information will contribute to basic science and strengthen the scientific basis for exercise therapy prescriptions for IP in clinical practice.
Language	English
Publishing date	2024-02-08
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2558898-9
ISSN	1663-4365
ISSN	1663-4365
DOI	10.3389/fnagi.2024.1359455
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Article ; Online: Effects of virtual reality-based rehabilitation on cognitive function and mood in multiple sclerosis: A systematic review and meta-analysis of randomized controlled trials.

Zhang, Jiongliang / Wu, Minmin / Li, Jinting / Song, Wenjing / Lin, Xiaoguang / Zhu, Luwen

Multiple sclerosis and related disorders

2024 Volume 87, Page(s) 105643

Abstract: Background: Multiple sclerosis (MS) is a disabling neurological disease that causes cognitive impairment and mental problems that occur in all MS phenotypes but are most common in patients with secondary progressive MS. Various degrees of cognitive ... ...

Abstract	Background: Multiple sclerosis (MS) is a disabling neurological disease that causes cognitive impairment and mental problems that occur in all MS phenotypes but are most common in patients with secondary progressive MS. Various degrees of cognitive impairment and mental health concerns are common among patients with MS (PwMS). Virtual reality (VR)-based rehabilitation is an innovative approach aimed at enhancing cognitive function and mood in PwMS. This study aims to perform a meta-analysis to assess the effects of VR-based rehabilitation on cognitive function and mood in PwMS. Methods: Using PubMed, Embase, the Cochrane Library, Web of Science, and the Physiotherapy Evidence Database (PEDro), a thorough database search was performed to identify randomized controlled trials (RCTs) examining the effects of VR on PwMS. Trials published until October 31, 2023, that satisfied our predetermined inclusion and exclusion criteria were included. Data were extracted, literature was examined, and the methodological quality of the included trials was assessed. StataSE version 16 was used for the meta-analysis. Results: Our meta-analysis included 461 patients from 10 RCTs. Primary outcomes: The Montreal Cognitive Assessment (MoCA) (weighted mean difference [WMD]=1.93, 95 % confidence interval [CI]=0.51-3.36, P = 0.008, I² = 75.4 %) the Spatial Recall Test (SPART) (WMD=3.57, 95 % CI=1.65-5.50, P < 0.001, I² = 0 %), immediate recall (standard mean difference [SMD]=0.37, 95 % CI=0.10-0.64, P = 0.007, I² = 0 %) and delayed recall ([SMD]=0.30, 95 % CI=0.06-0.54, P = 0.013, I² = 35.4 %) showed improvements in comparison to the control group in terms of global cognitive function immediate recall, delayed recall, and visuospatial abilities. Secondary outcomes: Compared to the control group, anxiety improved (standard mean difference [SMD]=0.36, 95 % CI=0.10-0.62, P = 0.007, I² = 43.1 %). However, there were no significant differences in processing speed, attention, working memory or depression. Conclusions: This systematic review provides valuable evidence for improving cognitive function and mood in PwMS through VR-based rehabilitation. In the future, VR-based rehabilitation may be a potential method to treat cognitive function and emotional symptoms of MS. Systematic review registration: PROSPERO; identifier: CRD42023474467.
Language	English
Publishing date	2024-05-09
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	2645330-7
ISSN	2211-0356 ; 2211-0348
ISSN (online)	2211-0356
ISSN	2211-0348
DOI	10.1016/j.msard.2024.105643
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Article: The relationship between fundamental motor skills and physical fitness in preschoolers: a short-term longitudinal study.

Chen, Jiebo / Song, Wenjing / Zhao, Xing / Lou, Hu / Luo, Dongmei

Frontiers in psychology

2023 Volume 14, Page(s) 1270888

Abstract: Purpose: Physical fitness and fundamental motor skills are two important aspects for the healthy development of preschoolers. Despite the growing interest in clarifying their relationship, the scarcity of longitudinal studies prevents us from ... ...

Abstract	Purpose: Physical fitness and fundamental motor skills are two important aspects for the healthy development of preschoolers. Despite the growing interest in clarifying their relationship, the scarcity of longitudinal studies prevents us from understanding causality. Method: This study employed a cross-lagged model with two time points to investigate the bidirectional relationship between these two aspects. A total of 174 preschoolers (54.0% girls) from 3 to 6 years old ( Results: The findings revealed a bidirectional predictive effect. The predictive strength of flexibility was found to be lower than other physical fitness aspects, while locomotor skills demonstrated a higher predictive strength than object control skills. Conclusion: This study indicates that physical fitness and fundamental motor skills mutually enhance each other in young children, and both should be emphasized in preschool sports education.
Language	English
Publishing date	2023-09-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2023.1270888
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Article ; Online: A case report of steroid-refractory bullous pemphigoid induced by immune checkpoint inhibitor therapy.

Guan, Shasha / Zhang, Linlin / Zhang, Junyan / Song, Wenjing / Zhong, Diansheng

Frontiers in immunology

2023 Volume 13, Page(s) 1068978

Abstract: The widespread use of immune checkpoint inhibitors in several malignancies has revealed new immune-related adverse events. Bullous pemphigoid (BP) is an antibody-driven autoimmune disease characterized by skin inflammation and fluid-filled bullae. Herein, ...

Abstract	The widespread use of immune checkpoint inhibitors in several malignancies has revealed new immune-related adverse events. Bullous pemphigoid (BP) is an antibody-driven autoimmune disease characterized by skin inflammation and fluid-filled bullae. Herein, a 69-year-old man with lung squamous cell carcinoma developed multiple vesicles and tense bullae 3 weeks after the initiation of a programmed death-1 (PD-1) inhibitor, pembrolizumab, and chemotherapy. Biopsy revealed a subepidermal bulla with lymphocytic and eosinophil infiltration, and immunohistochemical studies predominantly showed CD4
MeSH term(s)	Male ; Humans ; Aged ; Pemphigoid, Bullous/chemically induced ; Pemphigoid, Bullous/drug therapy ; Pemphigoid, Bullous/diagnosis ; Immune Checkpoint Inhibitors/adverse effects ; Blister/drug therapy ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Steroids/therapeutic use ; Lung Neoplasms/drug therapy ; Lung Neoplasms/complications
Chemical Substances	Immune Checkpoint Inhibitors ; Steroids
Language	English
Publishing date	2023-01-04
Publishing country	Switzerland
Document type	Case Reports ; Journal Article
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2022.1068978
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Article ; Online: Biomimetic Hyaluronic Acid-Based Brush Polymers Modulate Chondrocyte Homeostasis via ROS/Ca

Fan, Xiaopeng / Xie, Renjian / Song, Wenjing / Ouyang, Kunfu / Ren, Li

Biomacromolecules

2023 Volume 24, Issue 9, Page(s) 4240–4252

Abstract: Bionic mimics using natural cartilage matrix molecules can modulate the corresponding metabolic activity by improving the microenvironment of chondrocytes. A bionic brush polymer, HA/PX, has been found to reverse the loss of cartilage extracellular ... ...

Abstract	Bionic mimics using natural cartilage matrix molecules can modulate the corresponding metabolic activity by improving the microenvironment of chondrocytes. A bionic brush polymer, HA/PX, has been found to reverse the loss of cartilage extracellular matrix (ECM) and has promising applications in the clinical treatment of osteoarthritis (OA). However, the unknown bioremediation mechanism of HA/PX severely hinders its clinical translation. In OA, the massive loss of the ECM may be attributed to a decrease in transient receptor potential vanilloid 4 (TRPV4) activity, which affects reactive oxygen species (ROS) clearance and [Ca
MeSH term(s)	Humans ; Chondrocytes/metabolism ; Hyaluronic Acid/pharmacology ; TRPV Cation Channels/metabolism ; TRPV Cation Channels/pharmacology ; Reactive Oxygen Species/metabolism ; Biomimetics ; Osteoarthritis/drug therapy ; Interleukin-1beta/metabolism ; Antineoplastic Agents/pharmacology ; Homeostasis ; Cartilage, Articular/metabolism ; Cells, Cultured
Chemical Substances	Hyaluronic Acid (9004-61-9) ; TRPV Cation Channels ; Reactive Oxygen Species ; Interleukin-1beta ; Antineoplastic Agents ; TRPV4 protein, human
Language	English
Publishing date	2023-08-16
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1526-4602
ISSN (online)	1526-4602
DOI	10.1021/acs.biomac.3c00547
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Article ; Online: Subcellular visualization: Organelle-specific targeted drug delivery and discovery.

Shao, Xintian / Meng, Caicai / Song, Wenjing / Zhang, Tao / Chen, Qixin

Advanced drug delivery reviews

2023 Volume 199, Page(s) 114977

Abstract: Organelles perform critical biological functions due to their distinct molecular composition and internal environment. Disorders in organelles or their interacting networks have been linked to the incidence of numerous diseases, and the research of ... ...

Abstract	Organelles perform critical biological functions due to their distinct molecular composition and internal environment. Disorders in organelles or their interacting networks have been linked to the incidence of numerous diseases, and the research of pharmacological actions at the organelle level has sparked pharmacists' interest. Currently, cell imaging has evolved into a critical tool for drug delivery, drug discovery, and pharmacological research. The introduction of advanced imaging techniques in recent years has provided researchers with richer biological information for viewing and studying the ultrastructure of organelles, protein interactions, and gene transcription activities, leading to the design and delivery of precision-targeted drugs. Therefore, this reviews the research on organelles-targeted drugs based upon imaging technologies and development of fluorescent molecules for medicinal purposes. We also give a thorough analysis of a number of subcellular-level elements of drug development, including subcellular research instruments and methods, organelle biological event investigation, subcellular target and drug identification, and design of subcellular delivery systems. This review will make it possible to promote drug research from the individual/cellular level to the subcellular level, as well as give a new focus based on newly found organelle activities.
MeSH term(s)	Humans ; Pharmaceutical Preparations/chemistry ; Organelles ; Drug Delivery Systems ; Drug Development ; Drug Discovery
Chemical Substances	Pharmaceutical Preparations
Language	English
Publishing date	2023-06-28
Publishing country	Netherlands
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	639113-8
ISSN	1872-8294 ; 0169-409X
ISSN (online)	1872-8294
ISSN	0169-409X
DOI	10.1016/j.addr.2023.114977
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Article ; Online: Effects of traditional Chinese exercises on insomnia after coronavirus disease 2019: A protocol of systematic review and meta-analysis.

Zhang, Runtong / Song, Wenjing / Zhu, Luwen

Medicine

2022 Volume 101, Issue 47, Page(s) e31709

Abstract: Background: There is growing evidence that coronavirus disease 2019 (COVID-19) can trigger acute episodes of insomnia. Reports on the treatment of COVID-19-related insomnia are limited. Therefore, our study aims to perform a systematic evaluation and ... ...

Abstract	Background: There is growing evidence that coronavirus disease 2019 (COVID-19) can trigger acute episodes of insomnia. Reports on the treatment of COVID-19-related insomnia are limited. Therefore, our study aims to perform a systematic evaluation and meta-analysis of the effects of traditional Chinese exercises (TCEs) in patients with insomnia due to COVID-19. Methods: We will search the Embase, PubMed, Cochrane Library, Web of Science, MEDLINE, Scopus, Chinese Biomedical Literature Database, Chinese National Knowledge Infrastructure Database, and Wan Fang Database from December 1, 2019 to October 2, 2022 to identify all articles on treatment of COVID-19-related insomnia using TCEs. Two researchers will screen the articles and extract the relevant information. Results: The results will provide a systematic overview of the current evidence on the use of TCE to treat patients with insomnia after COVID-19. Conclusions: The conclusions of this study will help clarify the effects of TCEs on patients with insomnia after COVID-19.
MeSH term(s)	Humans ; Sleep Initiation and Maintenance Disorders/etiology ; Sleep Initiation and Maintenance Disorders/therapy ; COVID-19/complications ; COVID-19/therapy ; Exercise Therapy ; Exercise ; China ; Meta-Analysis as Topic ; Systematic Reviews as Topic
Language	English
Publishing date	2022-12-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000031709
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Article ; Online: Like the new and hate the old: The impact of fiscal decentralization on regional development strategy.

Liu, Min / Gong, Feng / Song, Wenjing

PloS one

2022 Volume 17, Issue 9, Page(s) e0273875

Abstract: This paper evaluates the impact of China's fiscal decentralization reform, namely the "Province-Managing-County" (PMC) fiscal reform, on local governments' regional development strategy using county-level data in China covering 2000 to 2013. Surprisingly, ...

Abstract	This paper evaluates the impact of China's fiscal decentralization reform, namely the "Province-Managing-County" (PMC) fiscal reform, on local governments' regional development strategy using county-level data in China covering 2000 to 2013. Surprisingly, after implementing the PMC fiscal reform, local governments will adjust their strategy of supporting zombie firms and attracting new firms, indicating that fiscal decentralization has changed the regional development strategies of local governments. We perform a difference-in-differences (DID) analysis and find that the PMC fiscal reform materially induces an average rise of 0.131 in newly added firms, an average decline of 0.383 in zombie firms, and no significant change in other firms. There is a pronounced substitution effect between zombie firms and newly added firms. We also find evidence supporting this argument: the government's subsidy, tax treatment, and financial support. Our study provides empirical evidence that local governments' regional development strategies can be affected by fiscal decentralization.
MeSH term(s)	China ; Hate ; Local Government ; Politics
Language	English
Publishing date	2022-09-09
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0273875
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Article ; Online: Quantification of underivatized amino acids in solid beverages using high-performance liquid chromatography and a potentiometric detector

Xu, Jiale / Wang, Yutong / Jiang, Junhui / Li, Xiaomeng / Xu, Yuheng / Song, Wenjing

Journal of Chromatography A. 2023 May, v. 1696 p.463986-

2023

Abstract: The simultaneous quantification of amino acids (AAs) in solid beverages without prior derivatization was explored by high-performance liquid chromatography (HPLC) coupled to a potentiometric detector. Included were threonine, leucine, methionine, ... ...

Abstract	The simultaneous quantification of amino acids (AAs) in solid beverages without prior derivatization was explored by high-performance liquid chromatography (HPLC) coupled to a potentiometric detector. Included were threonine, leucine, methionine, phenylalanine, and histidine. The potentiometric detector was made consisting of a copper(II)-selective electrode based on a polyvinyl chloride (PVC) membrane, and the potential changes in the detector were determined according to the coordination interactions between cupric copper ions released from the inner filling solution of the electrode and AAs. Conditions were optimized for effective separation and sensitive detection. Fundamental characteristics such as linearity, limits of detection, limits of quantitation, accuracy, precision, and robustness were validated experimentally. The calibration curves showed a linear relationship between peak heights and the injection concentrations of the AAs. The detection limits down to the sub-micromolar range were achieved under isocratic conditions, outperforming ultraviolet detection. The copper(II)-selective electrode had a minimum lifetime of one month. Some real samples were examined to further demonstrate the feasibility of the proposed approach. The measurement results obtained by the present method were in good agreement with those obtained by the HPLC-mass spectrometry (MS), indicating that the combined HPLC-potentiometric method is a potential option for quantifying AAs.
Keywords	calibration ; copper ; derivatization ; electrodes ; high performance liquid chromatography ; histidine ; leucine ; methionine ; phenylalanine ; poly(vinyl chloride) ; spectroscopy ; threonine ; Potentiometric detector ; High-performance liquid chromatography ; Polymeric membrane copper(ii)-electrode ; Hyphenated technique ; Amino acids
Language	English
Dates of publication	2023-05
Publishing place	Elsevier B.V.
Document type	Article ; Online
ZDB-ID	218139-3
ISSN	0021-9673 ; 0378-4355 ; 0376-737X
ISSN	0021-9673 ; 0378-4355 ; 0376-737X
DOI	10.1016/j.chroma.2023.463986
Database	NAL-Catalogue (AGRICOLA)

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