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Article: [Myxoid liposarcoma of the testis: A case report and review of the literature].

Song, Yan-Fang / Shi, Xiao-Lan / Zhou, Li

Zhonghua nan ke xue = National journal of andrology

2023 Volume 28, Issue 6, Page(s) 511–515

Abstract: Objective: To investigate the clinicopathological features, diagnosis, differential diagnosis, treatment and prognosis of myxoid liposarcoma (MLPS)of the testis.: Methods: We observed the clinicopathological and immunophenotypic characteristics of ... ...

Abstract	Objective: To investigate the clinicopathological features, diagnosis, differential diagnosis, treatment and prognosis of myxoid liposarcoma (MLPS)of the testis. Methods: We observed the clinicopathological and immunophenotypic characteristics of primary MLPS of the testis in a male patient and reviewed the relevant literature. Results: The tumor was located in the right testicular parenchyma, of multi-nodular growth microscopically. The tumor cells were stellate, fusiform, foamy and signet ring-like, with abundant mucus and a network of fine branched or plexiform capillaries in the stroma. Immune phenotype-related findings included positive p16 and H3K27ME3 tumor cells and CD34 vascular network, negative CD99, CK, Desmin, FLI agreed-1, S-100, SMA, STAT6, TFE3, α-inhibin and SOX1, and a Ki-67 proliferation index of about 15%. Conclusion: Primary MLPS of the testis is rare, which needs to be differentiated from myxosarcoma, rhabdomyosarcoma, myxoma, spindle cell or pleomorphic liposarcoma, and lipophiloma. Immunohistochemical markers Vimentin, s-100 and CD34 can assist in the diagnosis of the tumor.
MeSH term(s)	Male ; Humans ; Liposarcoma, Myxoid/pathology ; Testis/pathology ; Immunohistochemistry ; Antigens, CD34 ; Diagnosis, Differential
Chemical Substances	Antigens, CD34
Language	Chinese
Publishing date	2023-07-24
Publishing country	China
Document type	Review ; Case Reports ; English Abstract ; Journal Article
ZDB-ID	2267480-9
ISSN	1009-3591
ISSN	1009-3591
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Article: [Primary culture and identification of glomerular mesangial cells from mice with spontaneous lupus nephritis].

Chen, Heming / Lin, Ting / Song, Yanfang / Lin, Qing

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology

2022 Volume 38, Issue 7, Page(s) 611–616

Abstract: Objective To perform primary culture of glomerular mesangial cells, identify them from a mouse model of spontaneous lupus nephritis model and explore the optimal conditions for these procedures. Methods Nine control ICR mice and nine model MRL/lpr mice ... ...

Abstract	Objective To perform primary culture of glomerular mesangial cells, identify them from a mouse model of spontaneous lupus nephritis model and explore the optimal conditions for these procedures. Methods Nine control ICR mice and nine model MRL/lpr mice with spontaneous lupus nephritis were tested for autoantibodies using ELISA and urine protein was detected by bicinchoninic acid (BCA) assay at 12, 14 and 18 weeks of age. HE and Masson staining were used to observe the pathological changes of mice with lupus nephritis. Glomeruli were isolated using a cell sieve, while primary culture of glomerular mesangial cells was performed using the eugenic selection method. Glomerular mesangial cells of the MRL/lpr mice were identified based on cell morphology and immunocytochemical staining of α-smooth muscle actin and nephrin. Results In the model group, levels of anti-nuclear antibody and anti-double-stranded DNA antibodies significantly increased. Urine protein levels also increased significantly at 14 and 18 weeks of age. HE and masson staining of kidney tissue revealed pathological changes associated with lupus nephritis in the MRL/lpr mice from 12 weeks of age. Twenty-five days after seeding of the glomerular mesangial cells, those from the MRL/lpr mice gradually covered the bottom of the culture flasks, appearing star-shaped and fusiform by phase contrast microscopy. Immunocytochemistry showed that these cells were α-smooth muscle actin-positive and nephrin-negative, thus ruling out other glomerular intrinsic cells. Conclusion The primary culture of glomerular mesangial cells from mice with spontaneous lupus nephritis is developed and characterized.
MeSH term(s)	Actins ; Animals ; Antibodies, Antinuclear ; Lupus Nephritis ; Mesangial Cells ; Mice ; Mice, Inbred ICR ; Mice, Inbred MRL lpr
Chemical Substances	Actins ; Antibodies, Antinuclear
Language	Chinese
Publishing date	2022-07-03
Publishing country	China
Document type	Journal Article
ISSN	1007-8738
ISSN	1007-8738
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Article ; Online: Amphibian traits database: A global database on morphological traits of amphibians

Huang, Na / Sun, Xinyuan / Song, Yanfang / Yuan, Zhiyong / Zhou, Weiwei

Global Ecology and Biogeography. 2023 May, v. 32, no. 5 p.633-641

2023

Abstract: MOTIVATION: Amphibians are a diverse vertebrate group with more than 8,000 species, which is an important part of major terrestrial and freshwater ecosystems. Unfortunately, amphibians are experiencing a worldwide population decline. Trait information is ...

Abstract	MOTIVATION: Amphibians are a diverse vertebrate group with more than 8,000 species, which is an important part of major terrestrial and freshwater ecosystems. Unfortunately, amphibians are experiencing a worldwide population decline. Trait information is important for understanding the causes of endangerment. Additionally, such information is essential for ecological and evolutionary studies using trait‐based approaches. However, such data are scarcer for amphibians than for any other terrestrial vertebrate groups. To fill this gap, we collected morphological traits of global amphibians available from the literature and compiled a database to facilitate future studies. MAIN TYPES OF VARIABLES CONTAINED: Forty‐two morphological traits of Anura, 27 morphological traits of Caudata and 37 morphological traits of Gymnophiona. SPATIAL LOCATION AND GRAIN: Global. MAJOR TAXA: Amphibia. LEVEL OF MEASUREMENT: Species. SOFTWARE FORMAT: .csv.
Keywords	Anura ; Caudata ; Gymnophiona ; amphibians ; biogeography ; computer software ; databases ; freshwater ; population dynamics
Language	English
Dates of publication	2023-05
Size	p. 633-641.
Publishing place	John Wiley & Sons, Ltd
Document type	Article ; Online
Note	JOURNAL ARTICLE
ZDB-ID	2021283-5
ISSN	1466-8238 ; 1466-822X ; 0960-7447
ISSN (online)	1466-8238
ISSN	1466-822X ; 0960-7447
DOI	10.1111/geb.13656
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Nitrogen-Doped Titanium Dioxide for Selective Photocatalytic Oxidation of Methane to Oxygenates.

Feng, Guanghui / Mao, Jianing / Sun, Tong / Li, Guihua / Li, Shoujie / Dong, Xiao / Song, Yanfang / Wei, Wei / Chen, Wei

ACS applied materials & interfaces

2024 Volume 16, Issue 4, Page(s) 4600–4605

Abstract: Photocatalytic conversion of methane ( ... ...

Abstract	Photocatalytic conversion of methane (CH
Language	English
Publishing date	2024-01-19
Publishing country	United States
Document type	Journal Article
ISSN	1944-8252
ISSN (online)	1944-8252
DOI	10.1021/acsami.3c15614
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Article ; Online: Chemotherapy-initiated cysteine-rich protein 61 decreases acute B-lymphoblastic leukemia chemosensitivity.

Shi, Pengchong / Lin, Zhen / Song, Yanfang / Li, Zhaozhong / Zeng, Menglu / Luo, Li / Cao, Yingping / Zhu, Xianjin

Journal of cancer research and clinical oncology

2024 Volume 150, Issue 3, Page(s) 159

Abstract: Purpose: Chemoresistance is a major challenge for acute lymphoblastic leukemia (ALL) treatment. Cysteine-rich protein 61 (Cyr61) plays an important role in drug resistance modulation of tumor cells, and Cyr61 levels are increased in the bone marrow of ... ...

Abstract	Purpose: Chemoresistance is a major challenge for acute lymphoblastic leukemia (ALL) treatment. Cysteine-rich protein 61 (Cyr61) plays an important role in drug resistance modulation of tumor cells, and Cyr61 levels are increased in the bone marrow of patients with ALL and contribute to ALL cell survival. However, the effect of Cyr61 on B cell acute lymphoblastic leukemia (B-ALL) cell chemosensitivity and the regulatory mechanisms underlying Cyr61 production in bone marrow remain unknown. Methods: Nalm-6 and Reh human B-ALL cell lines were used in this study. Cyr61 levels were assessed using quantitative real-time PCR (qRT-PCR), western blot analysis, and enzyme-linked immunosorbent assay. The effect of Cyr61 on B-ALL cell chemosensitivity to daunorubicin (DNR) was evaluated using cell viability and flow cytometry analyses. The regulatory mechanisms of Cyr61 production in bone marrow were examined using qRT-PCR and western blot analysis. Results: Cyr61 knockdown and overexpression increased and decreased the chemosensitivity of B-ALL cells to DNR, respectively. Cyr61 attenuated chemotherapeutic drug-induced apoptosis by upregulating B cell lymphoma-2. Notably, DNR induced DNA damage response and increased Cyr61 secretion in B-ALL cells through the ataxia telangiectasia mutated (ATM)-dependent nuclear factor kappa B pathway. Conclusion: DNR induces Cyr61 production in B-ALL cells, and increased Cyr61 levels reduce the chemosensitivity of B-ALL cells. Consequently, targeting Cyr61 or related ATM signaling pathway may present a promising treatment strategy to enhance the chemosensitivity of patients with B-ALL.
MeSH term(s)	Humans ; Cysteine-Rich Protein 61/genetics ; Cysteine-Rich Protein 61/metabolism ; Cell Line, Tumor ; Signal Transduction ; NF-kappa B/metabolism ; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Chemical Substances	Cysteine-Rich Protein 61 ; NF-kappa B
Language	English
Publishing date	2024-03-26
Publishing country	Germany
Document type	Journal Article
ZDB-ID	134792-5
ISSN	1432-1335 ; 0171-5216 ; 0084-5353 ; 0943-9382
ISSN (online)	1432-1335
ISSN	0171-5216 ; 0084-5353 ; 0943-9382
DOI	10.1007/s00432-024-05692-8
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Article ; Online: Serum CYR61 as a potential biomarker to improve breast cancer diagnostics.

Lin, Zhen / Song, Yanfang / Qiu, Yaling / Shi, Pengchong / Zeng, Menglu / Cao, Yingping / Zhu, Xianjin

Biomarkers in medicine

2023 Volume 16, Issue 15, Page(s) 1121–1128

Abstract: Purpose: ...

Abstract	Purpose:
MeSH term(s)	Female ; Humans ; Biomarkers, Tumor ; Breast Neoplasms/diagnosis ; Enzyme-Linked Immunosorbent Assay ; ROC Curve
Chemical Substances	Biomarkers, Tumor ; CCN1 protein, human
Language	English
Publishing date	2023-01-06
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2481014-9
ISSN	1752-0371 ; 1752-0363
ISSN (online)	1752-0371
ISSN	1752-0363
DOI	10.2217/bmm-2022-0290
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Zs.A 6985: Show issues

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Article ; Online: Three-dimensional graphene aerogel mitigated the toxic impact of chloramphenicol wastewater on microorganisms in an EGSB reactor.

Song, Yanfang / Zhang, Zhaohan / Fang, Yanbin / Sun, Muchen / Jiang, Yuhuan / Li, Dongyi / Feng, Yujie

The Science of the total environment

2023 Volume 904, Page(s) 166796

Abstract: Anaerobic treatment of chloramphenicol wastewater holds significant promise due to its potential for bioenergy generation. However, the high concentration of organic matter and residual toxic substances in the wastewater severely inhibit the activity of ... ...

Abstract	Anaerobic treatment of chloramphenicol wastewater holds significant promise due to its potential for bioenergy generation. However, the high concentration of organic matter and residual toxic substances in the wastewater severely inhibit the activity of microorganisms. In this study, a three-dimensional graphene aerogel (GA), as a conductive material with high specific surface area (114.942 m
MeSH term(s)	Wastewater ; Graphite/toxicity ; Waste Disposal, Fluid/methods ; Chloramphenicol/toxicity ; Anaerobiosis ; Bioreactors/microbiology ; Sewage/microbiology ; Methane
Chemical Substances	Wastewater ; Graphite (7782-42-5) ; Chloramphenicol (66974FR9Q1) ; Sewage ; Methane (OP0UW79H66)
Language	English
Publishing date	2023-09-04
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2023.166796
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Article ; Online: Evaluating the stability and performance of a novel core-shell ZVI@C-montmorillonite particle for anaerobic treatment of chloramphenicol wastewater.

Song, Yanfang / Zhang, Zhaohan / Fang, Yanbin / Liu, Yanbo / Li, Dongyi / Feng, Yujie

Journal of hazardous materials

2023 Volume 460, Page(s) 132389

Abstract: ZVI@C-MP is a novel composite particle consisting of zero-valent iron (ZVI) enclosed within a carbon shell. The purpose of this composite material is to enhance the anaerobic treatment of wastewater containing chloramphenicol (CAP). This approach aims to ...

Abstract	ZVI@C-MP is a novel composite particle consisting of zero-valent iron (ZVI) enclosed within a carbon shell. The purpose of this composite material is to enhance the anaerobic treatment of wastewater containing chloramphenicol (CAP). This approach aims to address the initial challenge of excessive corrosion experienced by ZVI, followed by its subsequent passivation and inactivation. ZVI@C-MP was synthesized through a hydrothermal process and calcination, with montmorillonite as binder, it exhibits stability, iron-carbon microelectrolysis (ICME) properties, and strong adsorption for CAP. Its ICME actions include releasing iron ions (0.70 mg/L) and COD (11.3 mg/L), generating hydrogen (3.82%), and raising the pH from 6.30 to 7.71. With minimal structural changes, it achieved release equilibrium. ZVI@C-MP boasts high removal efficiency of CAP (98.96%) by adsorption, attributed to surface characteristics (surface area: 167.985 m
MeSH term(s)	Chloramphenicol ; Bentonite ; Wastewater ; Anaerobiosis ; Anti-Bacterial Agents ; Carbon ; Iron
Chemical Substances	Chloramphenicol (66974FR9Q1) ; Bentonite (1302-78-9) ; Wastewater ; Anti-Bacterial Agents ; Carbon (7440-44-0) ; Iron (E1UOL152H7)
Language	English
Publishing date	2023-09-01
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1491302-1
ISSN	1873-3336 ; 0304-3894
ISSN (online)	1873-3336
ISSN	0304-3894
DOI	10.1016/j.jhazmat.2023.132389
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Article ; Online: The potential value of serum chemerin in patients with breast cancer.

Song, Yanfang / Zhu, Xianjin / Lin, Zhen / Luo, Li / Wen, Dan

Scientific reports

2021 Volume 11, Issue 1, Page(s) 6564

Abstract: Breast cancer (BC) is one of the most dangerous malignant diseases in females. However, the reliable serum biomarkers of BC still need to be explored. Chemerin levels have been found to be associated with different types of cancer. This study aimed to ... ...

Abstract	Breast cancer (BC) is one of the most dangerous malignant diseases in females. However, the reliable serum biomarkers of BC still need to be explored. Chemerin levels have been found to be associated with different types of cancer. This study aimed to evaluate the role of serum chemerin as a biomarker of BC diagnosis, as well as the correlation between serum chemerin levels and clinicopathological features. The serum from 248 BC patients, 30 breast benign tumor patients, and 103 healthy controls were collected and serum chemerin levels were determined with enzyme-linked immunosorbent assay. We found that serum levels of chemerin in BC patients were higher than those in healthy control individuals (p < 0.05). The area under the ROC curve (AUC) for chemerin, CA15-3 and CEA was 0.703, 0.662 and 0.581, respectively, in distinguishing between breast cancer patients from healthy individuals, and the chemerin cutoff value was 100.327 ng/ml with a sensitivity of 56.60% and a specificity of 98.10%. The AUC for chemerin + CA15-3 was 0.822, which was higher than that for chemerin + CEA and CEA + CA15-3. Moreover, serum levels of chemerin were significantly associated with histologic grade, Ki67 expression, and menopausal status. However, no significant association was found between serum levels of chemerin and age, tumor size, metastase, ER status, PR status, and HER-2 status. Overall, our study suggested that the combination of chemerin with CA15-3 achieves relatively better diagnostic performance in the breast cancer. Elevated serum chemerin is associated with Ki67 expression levels and histologic grade.
MeSH term(s)	Adult ; Biomarkers, Tumor ; Breast Neoplasms/blood ; Breast Neoplasms/diagnosis ; Breast Neoplasms/therapy ; Carcinoembryonic Antigen/blood ; Chemokines/blood ; Female ; Humans ; Middle Aged ; Mucin-1/blood ; Neoplasm Grading ; Neoplasm Staging ; Prognosis ; ROC Curve ; Young Adult
Chemical Substances	Biomarkers, Tumor ; Carcinoembryonic Antigen ; Chemokines ; MUC1 protein, human ; Mucin-1 ; RARRES2 protein, human
Language	English
Publishing date	2021-03-22
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-021-85986-w
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Article: Case Report: A novel

Chen, Yuhong / Chen, Junyong / Long, Liansheng / Han, Leng / Mi, Xiaohui / Song, Yanfang / Cheng, Huanqing / Zhang, Yanrui / Cheng, Liyang

Frontiers in oncology

2023 Volume 13, Page(s) 1260706

Abstract: In this report, we present a case study of a 64-year-old female who was diagnosed with gastrointestinal stromal tumors (GISTs) and subsequently developed liver metastases despite undergoing radical resection. Next-generation sequencing (NGS) assays ... ...

Abstract	In this report, we present a case study of a 64-year-old female who was diagnosed with gastrointestinal stromal tumors (GISTs) and subsequently developed liver metastases despite undergoing radical resection. Next-generation sequencing (NGS) assays indicated that the tumor lacked
Language	English
Publishing date	2023-11-09
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2649216-7
ISSN	2234-943X
ISSN	2234-943X
DOI	10.3389/fonc.2023.1260706
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