Article: Effect of Remdesivir on mortality and length of stay in hospitalized COVID-19 patients: A single center study.
Pakistan journal of medical sciences
2022 Volume 38, Issue 2, Page(s) 405–410
Abstract: Objectives: To see the difference in mortality among hospitalized COVID-19 patients given Remdesivir (RDV) with those who were not given RDV.: Methods: A prospective cohort study was conducted on patients who were admitted to the COVID-19 isolation ... ...
| Abstract | Objectives: To see the difference in mortality among hospitalized COVID-19 patients given Remdesivir (RDV) with those who were not given RDV. Methods: A prospective cohort study was conducted on patients who were admitted to the COVID-19 isolation unit at The Indus Hospital, Korangi Campus Karachi between March and June 2020. Results: Groups were similar in age and gender distribution. RDV group was more hypoxic, had severe ARDS and needed higher Oxygen support compared to non-RDV group (p=0.000). Median SOFA score was 2 in RDV vs 5 in non-RDV (p=0.000). More than moderate COVID pneumonia was found in 92% of the RDV group while 89% of non-RDV group (p value=0.001). Median day of illness to administer Remdesivir was 10. There was no difference in mortality (45.5% in RDV vs 40.4% in non-RDV; p=0.4) between the two groups. Median length of hospital stay was 12 days (IQR=7.5-14.5) in RDV group compared to 10 days (IQR=6-14) in non-RDV group (p=0.009). Conclusion: RDV did not show any difference in in-hospital mortality in our patients. More patients had severe ARDS in the RDV group while patients in the non-RDV group had higher SOFA score and multi-organ failure. Length of stay was longer in patients receiving Remdesivir. |
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| Language | English | |||||
| Publishing date | 2022-03-16 | |||||
| Publishing country | Pakistan | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 2032827-8 | |||||
| ISSN | 1681-715X ; 1682-024X ; 1017-4699 | |||||
| ISSN (online) | 1681-715X | |||||
| ISSN | 1682-024X ; 1017-4699 | |||||
| DOI | 10.12669/pjms.38.ICON-2022.5779 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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