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  1. Article ; Online: Contrast-Enhanced Ultrasonography in the Diagnosis and Treatment Modulation of Breast Cancer

    Ioana Boca (Bene) / Sorin M. Dudea / Anca I. Ciurea

    Journal of Personalized Medicine, Vol 11, Iss 2, p

    2021  Volume 81

    Abstract: The aim of this paper is to highlight the role of contrast-enhanced ultrasound in breast cancer in terms of diagnosis, staging and follow-up of the post-treatment response. Contrast-enhanced ultrasound (CEUS) is successfully used to diagnose multiple ... ...

    Abstract The aim of this paper is to highlight the role of contrast-enhanced ultrasound in breast cancer in terms of diagnosis, staging and follow-up of the post-treatment response. Contrast-enhanced ultrasound (CEUS) is successfully used to diagnose multiple pathologies and has also clinical relevance in breast cancer. CEUS has high accuracy in differentiating benign from malignant lesions by analyzing the enhancement characteristics and calculating the time-intensity curve’s quantitative parameters. It also has a significant role in axillary staging, especially when the lymph nodes are not suspicious on clinical examination and have a normal appearance on gray-scale ultrasound. The most significant clinical impact consists of predicting the response to neoadjuvant chemotherapy, which offers the possibility of adjusting the therapy by dynamically evaluating the patient. CEUS is a high-performance, feasible, non-irradiating, accessible, easy-to-implement imaging method and has proven to be a valuable addition to breast ultrasound.
    Keywords contrast-enhanced ultrasound ; breast cancer ; SonoVue ; neoadjuvant chemotheraphy ; sentinel lymph node ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Cost Analysis on Imaging Diagnostic Techniques in Cerebral and Abdominal Neonatal Pathology

    Carolina BOTAR-JID / Sorin M. DUDEA / Cristiana A. CIORTEA / Sorana D. BOLBOACĂ / Anca CIUREA

    Applied Medical Informatics, Vol 25, Iss 3-4, Pp 55-

    2009  Volume 64

    Abstract: Background: Improvement of health care quality and cost control are the main aims of the health care reform in Romania. Objective: The aims of the research are to analyse the trend of costs for imaging techniques used as diagnostic tools for cerebral and ...

    Abstract Background: Improvement of health care quality and cost control are the main aims of the health care reform in Romania. Objective: The aims of the research are to analyse the trend of costs for imaging techniques used as diagnostic tools for cerebral and abdominal neonatal pathology and to study the relationship between cost and diagnostic benefits. Design: This is a retrospective observational study design without a control group, conducted in the Radio-Imaging Department, Cluj District University Hospital, Romania, from October 2000 to February 2006. Patients: The study population was represented by neonates investigated in the Radio-Imaging Department, Cluj District University Hospital. Intervention: Five imaging diagnostic techniques used in the diagnosis of cerebral and abdominal neonatal pathology were investigated. Measurements: The costs of the investigated techniques were calculated. The concordance between clinical and imaging diagnostic was recorded. Results: Magnetic resonance proved to be the most expensive investigation. The rate between the raising of costs on investigation type on year was constant. The average cost of imaging investigations for patients with identified pathological aspects (€ 42.72) was not statistically significant (p > 0.05) compared with the average cost for patients with no pathologic imaging aspects (€ 37.62). The concordance between the clinical suspicion and the radio-imaging diagnosis was of 52.35%. Conclusions: The raise of radio-imaging investigation costs had a decreasing tendency over the years studied, decrease explained by the stabilization of the Romanian monetary market. The results on concordance analysis lead to the necessity of training of both clinicians and radiologists.
    Keywords Neonate ; Imaging Investigation Costs ; Radio-Imaging Pathological Findings ; Clinical-Imaging Concordance ; Computer applications to medicine. Medical informatics ; R858-859.7
    Subject code 610
    Language English
    Publishing date 2009-12-01T00:00:00Z
    Publisher Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Assessment of Sonoelastography as Diagnosis Tool of Inflammatory Myopathies

    Carolina BOTAR-JID / Sorana D. BOLBOACĂ / Laura DAMIAN / Sorin M. DUDEA / Cosmin PANTILIE / Sergiu NEDEVSCHI / Radu BADEA

    Applied Medical Informatics, Vol 27, Iss 4, Pp 81-

    2010  Volume 89

    Abstract: Background: Inflammatory myopathies represent a special group of pathology. Establishing the correct diagnosis in the early phase and a better follow-up are the main objective for improving the life quality of these patients. Objective: The aim of this ... ...

    Abstract Background: Inflammatory myopathies represent a special group of pathology. Establishing the correct diagnosis in the early phase and a better follow-up are the main objective for improving the life quality of these patients. Objective: The aim of this research was to assess the usefulness of sonoelastography in diagnosis of inflammatory myopathies. Material and Method: A prospective longitudinal study with a control group was carried out in the Radio-Imaging Department, Cluj-Napoca District University Hospital, Romania, from May 2007 to July 2010. Measurements: Image Processing 2.8 software was used to analyze the elastographic images in correlation with clinical and biochemical data was used. Results: Analysis of Receiver Operating Characteristic curves statistics for elastography parameters showed significant values for the following parameters: average green color, average blue color, average intensity of color, dispersion of red, dispersion of green, and dispersion of hue. Conclusions: Our study highlighted the utility of some elastography parameters in the diagnosis of inflammatory myopathies; the parameter proved to be statistically different in case group compared to control. Anyway, standardization of sonoelastography and larger studies are required to ensure accurate diagnosis, reproductibility and reliability.
    Keywords Receiver Operating Characteristic (ROC) curve ; Cutoff value ; Dedicated software ; Sonoelastography ; Inflammatory Myopathies ; Computer applications to medicine. Medical informatics ; R858-859.7
    Subject code 610
    Language English
    Publishing date 2010-12-01T00:00:00Z
    Publisher Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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