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  1. Article ; Online: Atypical Presentation of Small Lymphocytic Lymphoma with Pericardial Effusion.

    Nnaoma, Christopher / Chika-Nwosuh, Ogechukwu / Mbonu, Ikechukwu / Sossou, Christoph W / Okonkwo, Christian C / Isedeh, Anthony

    The American journal of case reports

    2019  Volume 20, Page(s) 1128–1131

    Abstract: BACKGROUND Small lymphocytic lymphoma (SLL) is a low-grade B-cell non-Hodgkin lymphoma and is the solid tumor equivalent of chronic lymphocytic leukemia (CLL) that is found in the peripheral blood. SLL typically presents with lymphadenopathy and is ... ...

    Abstract BACKGROUND Small lymphocytic lymphoma (SLL) is a low-grade B-cell non-Hodgkin lymphoma and is the solid tumor equivalent of chronic lymphocytic leukemia (CLL) that is found in the peripheral blood. SLL typically presents with lymphadenopathy and is rarely associated with cardiac involvement. This report is of a case of lymphomatous pericardial effusion in a 61-year-old woman who presented with dyspnea. CASE REPORT A 61-year-old woman presented to the emergency department with a three-month history of worsening shortness of breath on exertion. Her symptoms progressed to shortness of breath at rest, with night sweats and chills. She had no weight loss. She was found to have a pericardial effusion, and an urgent pericardiocentesis was performed to prevent cardiac tamponade. Analysis of the pericardial fluid was consistent with a diagnosis of SLL. A bone marrow biopsy and a biopsy of a renal mass were consistent with a diagnosis of SLL. She was treated with rituximab and bendamustine with granulocyte-colony stimulating factor (G-CSF) support and was discharged home. CONCLUSIONS A case is presented of a rare association between SLL and pericardial effusion with a favorable outcome following urgent pericardiocentesis to prevent cardiac tamponade followed by chemotherapy.
    MeSH term(s) Computed Tomography Angiography ; Dyspnea/etiology ; Female ; Humans ; Leukemia, Lymphocytic, Chronic, B-Cell/diagnosis ; Middle Aged ; Pericardial Effusion/diagnostic imaging ; Pericardial Effusion/etiology ; Tomography, X-Ray Computed
    Language English
    Publishing date 2019-07-31
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/AJCR.915576
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Diversity in U.S. Cardiovascular Trainees and Leadership Where we are and What the Future Holds.

    Sossou, Christoph W / Fakhra, Sadaf / Batra, Kavita / Nouthe, Brice / Okoh, Alexis / Phillips-Wilson, Tasha / Kuria, Carolyne N / Hawwass, Dalia / Ogunniyi, Modele O / Singh, Aditi / Cohen, Marc / Dawn, Buddhadeb / Ahsan, Chowdhury H

    Current problems in cardiology

    2022  Volume 48, Issue 3, Page(s) 101518

    Abstract: Cardiovascular (CV) outcomes can be improved with commonality between provider and patient regarding gender and race/ethnicity. Slow growth in CV care provider diversity is an obstacle for women and underrepresented groups. The hope for more equitable ... ...

    Abstract Cardiovascular (CV) outcomes can be improved with commonality between provider and patient regarding gender and race/ethnicity. Slow growth in CV care provider diversity is an obstacle for women and underrepresented groups. The hope for more equitable outcomes is unlikely to be realized unless trends change in selection of CV fellows and program directors (PDs). We investigate longitudinal trends of gender and racial/ethnic composition of CV FITs. De-identified demographic data were compiled in a descriptive cross-sectional study from AAMC of internal medicine (IM) residents and CV FITs from 2011 through 2021 to evaluate gender and race/ethnicity trends among CV trainees. Trends of CV fellows who later became program directors were analyzed. In the US between 2011 and 2021, 53% of IM residents were male while 40% female (7% unreported). Among CV FITs, 78% were male and 21% female. Races/ethnicities among CV FITs consisted of 36% non-Hispanic white, 28% non-Hispanic Asian, 5% Hispanic, 4%Black, and 25% were classified within other race/ethnicity categories. The proportion who became CV program directors followed similarly: 79% of PDs were male and 21% female. Demographic profiles for CV FITs have not significantly changed over the past decade despite increased diversity among IM residents. Efforts to improve diversity of CV FITs and PDs need to be analyzed. Slow growth of diversity in CV FITs is outpaced by rising patient diversity, leading to disparities in care and poorer CV outcomes for women and underrepresented minorities. Recruiting, training, and retaining diverse CV FITs is necessary.
    MeSH term(s) Humans ; Male ; Female ; United States/epidemiology ; Cross-Sectional Studies ; Leadership ; Ethnicity ; Hispanic or Latino ; Minority Groups
    Language English
    Publishing date 2022-12-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 441230-8
    ISSN 1535-6280 ; 0146-2806
    ISSN (online) 1535-6280
    ISSN 0146-2806
    DOI 10.1016/j.cpcardiol.2022.101518
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Efficacy of Manual Hemostasis for Percutaneous Axillary Artery Intra-Aortic Balloon Pump Removal.

    Tayal, Rajiv / DiVita, Michael / Sossou, Christoph W / Okoh, Alexis K / Stelling, Kelly / McCabe, James M / Kaki, Amir / Wasty, Najam / Baran, David A

    Journal of interventional cardiology

    2020  Volume 2020, Page(s) 8375878

    Abstract: Background: The prevalence of peripheral vascular disease has led to the re-emergence of percutaneous axillary vascular access as a suitable alternative access site to femoral artery. We sought to investigate the efficacy and safety of manual hemostasis ...

    Abstract Background: The prevalence of peripheral vascular disease has led to the re-emergence of percutaneous axillary vascular access as a suitable alternative access site to femoral artery. We sought to investigate the efficacy and safety of manual hemostasis in the axillary artery.
    Methods: Data were collected from a prospective internal registry of patients who had a Maquet® (Rastatt, Germany) Mega 50 cc intra-aortic balloon pumps (IABP) placed in the axillary artery position. They were anticoagulated with weight-based intravenous heparin to maintain an activated partial thromboplastin time (aPTT) of 50-80 seconds. Anticoagulation was discontinued 2 hours prior to the device explantation. Manual compression was used to achieve the hemostasis of the axillary artery. Vascular and bleeding complications attributable to manual hemostasis were classified based on the Valve Academic Research Consortium-2 (VARC-2) and Bleeding Academic Research Consortium-2 (BARC-2) classifications, respectively.
    Results: 29 of 46 patients (63%) achieved axillary artery homeostasis via manual compression. The median duration of IABP implantation was 12 days (range 1-54 days). Median compression time was 20 minutes (range 5-60 minutes). There were no major vascular or bleeding complications as defined by the VARC-2 and BARC-2 criteria, respectively.
    Conclusion: Manual compression of the axillary artery appears to be an effective and safe method for achieving hemostasis. Large prospective randomized control trials may be needed to corroborate these findings.
    MeSH term(s) Axillary Artery/surgery ; Catheterization, Peripheral/adverse effects ; Catheterization, Peripheral/methods ; Device Removal/adverse effects ; Device Removal/methods ; Endotamponade/adverse effects ; Endotamponade/methods ; Female ; Heart-Assist Devices ; Hemorrhage/etiology ; Hemorrhage/therapy ; Humans ; Male ; Middle Aged ; Prospective Studies ; Treatment Outcome
    Language English
    Publishing date 2020-07-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1036325-7
    ISSN 1540-8183 ; 0896-4327
    ISSN (online) 1540-8183
    ISSN 0896-4327
    DOI 10.1155/2020/8375878
    Database MEDical Literature Analysis and Retrieval System OnLINE

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