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  1. Article: Left Ventricular Papillary Fibroelastoma.

    Balboa, Cristina / Souaf, Souhayla / Suárez, José M / El-Diasty, Mohammad M / Fernandez, Angel L

    Portuguese journal of cardiac thoracic and vascular surgery

    2023  Volume 30, Issue 1, Page(s) 49–52

    Abstract: Introduction: Cardiac papillary fibroelastoma is a rare benign primary cardiac tumor typically found on the valvular structures of the heart. Nonvalvular papillary fibroelastomas are exceedingly rare. We report the case of a 66-year-old male who ... ...

    Abstract Introduction: Cardiac papillary fibroelastoma is a rare benign primary cardiac tumor typically found on the valvular structures of the heart. Nonvalvular papillary fibroelastomas are exceedingly rare. We report the case of a 66-year-old male who presented with cerebellar infarctions and was found to have a mobile mass attached to the endocardial surface of the anteroseptal wall of the left ventricle. Cardiac magnetic resonance imaging demonstrated late gadolinium enhancement. Surgical excision of the cardiac mass was performed via the transaortic approach without intra-operative complications. Histopathologic examination confirmed the diagnosis of a papillary fibroelastoma. Some aspects related to the etiology, diagnosis and management of this entity are discussed.
    MeSH term(s) Male ; Humans ; Aged ; Heart Ventricles/diagnostic imaging ; Cardiac Papillary Fibroelastoma/complications ; Echocardiography, Transesophageal ; Contrast Media ; Gadolinium ; Heart Neoplasms/diagnostic imaging
    Chemical Substances Contrast Media ; Gadolinium (AU0V1LM3JT)
    Language English
    Publishing date 2023-04-04
    Publishing country Portugal
    Document type Case Reports ; Journal Article
    ISSN 2184-9927
    ISSN 2184-9927
    DOI 10.48729/pjctvs.332
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Floating thrombus in the ascending aorta causing repeated arterial embolisms.

    Adrio, Belén / Souaf, Souhayla / Al-Hamwy, Zaid / García, Javier / L Fernández, Angel

    Revista portuguesa de cirurgia cardio-toracica e vascular : orgao oficial da Sociedade Portuguesa de Cirurgia Cardio-Toracica e Vascular

    2018  Volume 25, Issue 1-2, Page(s) 95–98

    Abstract: Free-floating thrombus in an otherwise normal ascending aorta is a rare finding. We report the case of a 61-year-old woman admitted for brain and peripheral arterial embolisms. Echocardiography was not able to detect the source of embolus. Computed ... ...

    Abstract Free-floating thrombus in an otherwise normal ascending aorta is a rare finding. We report the case of a 61-year-old woman admitted for brain and peripheral arterial embolisms. Echocardiography was not able to detect the source of embolus. Computed tomographic scan demonstrated a large floating mass attached to the posterior wall of the distal ascending aorta. The thrombus was successfully removed with the patient under deep hypothermic circulatory arrest. Some aspects regarding pathogenesis, diagnosis and treatment are discussed.
    MeSH term(s) Aorta/diagnostic imaging ; Aorta/surgery ; Aortic Diseases/diagnostic imaging ; Aortic Diseases/surgery ; Circulatory Arrest, Deep Hypothermia Induced ; Embolism/etiology ; Female ; Humans ; Intracranial Embolism/etiology ; Middle Aged ; Peripheral Arterial Disease/etiology ; Recurrence ; Thrombosis/complications ; Thrombosis/diagnostic imaging ; Thrombosis/surgery ; Tomography, X-Ray Computed
    Language English
    Publishing date 2018-11-15
    Publishing country Portugal
    Document type Case Reports ; Journal Article
    ISSN 0873-7215
    ISSN 0873-7215
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Clinical Profiling and Biomarkers for Post-Operative Atrial Fibrillation Prediction in Patients Undergoing Cardiac Surgery.

    Iglesias-Álvarez, Diego / Fu, Xiaoran / Martínez-Cereijo, José Manuel / Agra-Bermejo, Rosa María / Veiras-Del Río, Sonia / Selas-Cobos, Salomé / Rial-Munin, María Victoria / Eiras-Mariño, María / Martínez-Salgado, Adrián / Taboada-Muñiz, Manuel / Reija-López, Laura / Souaf, Souhayla / García-Carro, Javier / Fernández-González, Ángel Luis / Adrio-Nazar, Belén / González-Juanatey, José Ramón / Eiras, Sonia / Rodríguez-Mañero, Moisés

    Journal of clinical medicine

    2023  Volume 12, Issue 10

    Abstract: Post-operative atrial fibrillation (POAF) is the most common arrhythmia in the post-operative period after cardiac surgery. We aim to investigate the main clinical, local, and/or peripheral biochemical and molecular predictors for POAF in patients ... ...

    Abstract Post-operative atrial fibrillation (POAF) is the most common arrhythmia in the post-operative period after cardiac surgery. We aim to investigate the main clinical, local, and/or peripheral biochemical and molecular predictors for POAF in patients undergoing coronary and/or valve surgery. Between August 2020 and September 2022, consecutive patients undergoing cardiac surgery without previous history of AF were studied. Clinical variables, plasma, and biological tissues (epicardial and subcutaneous fat) were obtained before surgery. Pre-operative markers associated with inflammation, adiposity, atrial stretch, and fibrosis were analyzed on peripheral and local samples with multiplex assay and real-time PCR. Univariate and multivariate logistic regression analyses were performed in order to identify the main predictors for POAF. Patients were followed-up until hospital discharge. Out of 123 consecutive patients without prior AF, 43 (34.9%) developed POAF during hospitalization. The main predictors were cardiopulmonary bypass time (odds ratio (OR) 1.008 (95% confidence interval (CI), 1.002-1.013),
    Language English
    Publishing date 2023-05-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12103565
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  4. Article ; Online: Life expectancy after surgical aortic valve replacement for low-gradient aortic stenosis with preserved ejection fraction.

    Hernández-Vaquero, Daniel / Rodríguez-Caulo, Emiliano / Vigil-Escalera, Carlota / Blanco-Herrera, Óscar / Berastegui, Elisabet / Arias-Dachary, Javier / Souaf, Souhayla / Parody, Gertrudis / Laguna, Gregorio / Adsuar, Alejandro / Castellá, Manel / Valderrama, José F / Pulitani, Ivana / Cánovas, Sergio / Ferreiro, Andrea / García-Valentín, Antonio / Carnero, Manuel / Pareja, Pilar / Corrales, José A /
    Blázquez, José A / Macías, Diego / Fletcher-Sanfeliu, Delfina / Martínez, Daniel / Martín, Elio / Martín, Miren / Margarit, Juan / Hernández-Estefanía, Rafael / Monguió, Emilio / Otero, Juan / Silva, Jacobo

    Revista espanola de cardiologia (English ed.)

    2022  

    Abstract: Introduction and objectives: Surgical aortic valve replacement (SAVR) can modify the natural history of severe aortic stenosis (SAS). However, compared with the general population, these patients have a loss of life expectancy. The life expectancy of ... ...

    Abstract Introduction and objectives: Surgical aortic valve replacement (SAVR) can modify the natural history of severe aortic stenosis (SAS). However, compared with the general population, these patients have a loss of life expectancy. The life expectancy of patients who undergo SAVR due to low-gradient SAS with preserved left ventricular ejection fraction (LVEF) is unknown.
    Methods: We included all patients between 50 and 65 years who underwent isolated SAVR in 27 Spanish centers during an 18-year period. We analyzed observed and expected survival at 18 years in patients with low-gradient SAS with preserved LVEF and all other types of SAS. We used propensity score matching to compare the life expectancy of patients with low-gradient SAS with preserved LVEF vs those with high-gradient SAS with preserved LVEF.
    Results: We analyzed 5084 patients, of whom 413 had low-gradient SAS with preserved LVEF. For these patients, observed survival at 10, 15 and 18 years was 86.6% (95%CI, 85.3-87.8), 75% (95%CI, 72.7-77.2), and 63.5% (95%CI, 58.8-67.8). Expected survival at 10, 15 and 18 years was 90.2%, 82.1%, and 75.7%. In the matched sample, survival of patients with low-gradient SAS with preserved LVEF was similar to that of patients with high-gradient with preserved LVEF, log-rank test, P=.95; HR=1 (95%CI, 0.7-1.4; P=.95).
    Conclusions: There is a loss of life expectancy in patients with all types of SAS undergoing SAVR. This loss is higher in patients with left ventricular dysfunction and lower in patients with low-gradient or high-gradient aortic stenosis with preserved LVEF. The benefit of surgery is similar between these last 2 groups.
    Language Spanish
    Publishing date 2022-06-19
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2022.05.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Differences in life expectancy between men and women after aortic valve replacement.

    Hernandez-Vaquero, Daniel / Rodriguez-Caulo, Emiliano / Vigil-Escalera, Carlota / Blanco-Herrera, Oscar / Berastegui, Elisabet / Arias-Dachary, Javier / Souaf, Souhayla / Parody, Gertrudis / Laguna, Gregorio / Adsuar, Alejandro / Castellá, Manel / Valderrama, José F / Pulitani, Ivana / Cánovas, Sergio / Ferreiro, Andrea / García-Valentín, Antonio / Carnero, Manuel / Pareja, Pilar / Corrales, José A /
    Blázquez, José A / Macías, Diego / Fletcher-Sanfeliu, Delfina / Martínez, Daniel / Martín, Elio / Martín, Miren / Margarit, Juan / Hernández-Estefanía, Rafael / Monguió, Emilio / Otero, Juan / Silva, Jacobo

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2021  Volume 60, Issue 3, Page(s) 681–688

    Abstract: Objectives: Some researchers have observed an increased number of deaths during the follow-up of young patients who undergo aortic valve replacement due to severe aortic stenosis, suggesting that this procedure does not restore their life expectancy. ... ...

    Abstract Objectives: Some researchers have observed an increased number of deaths during the follow-up of young patients who undergo aortic valve replacement due to severe aortic stenosis, suggesting that this procedure does not restore their life expectancy. Our goal was to confirm these findings and explore sex-based differences.
    Methods: All patients between 50 and 65 years of age who underwent isolated aortic valve replacement in 27 Spanish centres during an 18-year period were included. We compared observed and expected survival at 15 years of follow-up and estimated the cumulative incidence of death from a competing risks point of view. We stratified by sex and analysed if being a woman was an independent risk factor for death.
    Results: For men, the observed survival at 10 and 15 years of follow-up was 85% [95% confidence interval (CI) 83.6%-86.4%] and 72.3% (95% CI 69.7%-74.7%), respectively whereas the expected survival was 88.1% and 78.8%. For women, the observed survival at 10 and 15 years was 85% (95% CI 82.8%-86.9%) and 73% (95% CI 69.1%-76.4%), whereas the expected survival was 94.6% and 89.4%. At 15 years of follow-up, the cumulative incidence of death due to the disease in men and women was 8.2% and 16.7%, respectively. In addition, being a woman was an independent risk factor for death (hazard ratio = 1.23 (95% CI 1.02-1.48; P = 0.03).
    Conclusions: After the aortic valve replacement, men and women do not have their life expectancy restored, but this loss is much higher in women than in men. In addition, being a woman is a risk factor for long-term death. Reasons for these findings are unknown and must be investigated.
    MeSH term(s) Aortic Valve/surgery ; Aortic Valve Stenosis/surgery ; Female ; Heart Valve Prosthesis ; Heart Valve Prosthesis Implantation/adverse effects ; Humans ; Life Expectancy ; Male ; Risk Factors ; Transcatheter Aortic Valve Replacement/adverse effects ; Treatment Outcome
    Language English
    Publishing date 2021-03-26
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezab140
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Life expectancy after aortic valve replacement in young patients.

    Hernández-Vaquero, Daniel / Rodríguez-Caulo, Emiliano / Vigil-Escalera, Carlota / Blanco-Herrera, Óscar / Berastegui, Elisabet / Arias-Dachary, Javier / Souaf, Souhayla / Parody, Gertrudis / Laguna, Gregorio / Adsuar, Alejandro / Castellá, Manel / Valderrama, José F / Pulitani, Ivana / Cánovas, Sergio / Ferreiro, Andrea / García-Valentín, Antonio / Carnero, Manuel / Pareja, Pilar / Corrales, José A /
    Blázquez, José A / Macías, Diego / Fletcher-Sanfeliu, Delfina / Martínez, Daniel / Martín, Elio / Martín, Miren / Margarit, Juan / Hernández-Estefanía, Rafael / Monguió, Emilio / Otero, Juan / Silva, Jacobo

    Revista espanola de cardiologia (English ed.)

    2021  Volume 75, Issue 4, Page(s) 294–299

    Abstract: Introduction and objectives: In young patients with severe aortic stenosis, it is unknown whether their life expectancy restored after aortic valve replacement (AVR) is unknown.: Methods: We analyzed all patients aged between 50 and 65 years who ... ...

    Abstract Introduction and objectives: In young patients with severe aortic stenosis, it is unknown whether their life expectancy restored after aortic valve replacement (AVR) is unknown.
    Methods: We analyzed all patients aged between 50 and 65 years who underwent isolated AVR in 27 Spanish centers during an 18-year period. We compared observed and expected survival at 15 years of follow-up. We repeated all analyses for patients without complications in the postoperative period.
    Results: A total of 5084 patients were analyzed. For the overall sample, observed survival at 10 and 15 years was 85.3% (95%CI, 84.1%-86.4%) and 73.7% (95%CI, 71.6%-75.6%), respectively. Expected survival was 90.1% and 82.1%. Cumulative relative survival for 1, 5, 10 and 15 years of follow-up was 97.4% (95%CI, 96.9%-97.9%), 96.5% (95%CI, 95.7%-97.3%), 94.7% (95%CI, 93.3%-95.9%), and 89.8% (95%CI, 87.3%-92.1%). For patients without complications, cumulative relative survival for 1, 5, 10 and 15 years was 100.3% (95%CI, 99.8%-100.5%), 98.9% (95%CI 97.6% -99.9%), 97.3% (95%CI, 94.9%-99.4%), and 91.9% (95%CI, 86.5%-96.8%).
    Conclusions: Life expectancy in young patients who have severe aortic stenosis and undergo AVR is lower than that of the general population. Life expectancy of individuals without complications during the postoperative period is also reduced. Therefore, baseline characteristics are likely the main factors that explain the reduction in life expectancy.
    MeSH term(s) Aged ; Aortic Valve/surgery ; Aortic Valve Stenosis ; Heart Valve Prosthesis ; Heart Valve Prosthesis Implantation/adverse effects ; Humans ; Life Expectancy ; Middle Aged ; Risk Factors ; Transcatheter Aortic Valve Replacement/adverse effects ; Treatment Outcome
    Language Spanish
    Publishing date 2021-06-05
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2021.04.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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