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Article ; Online: Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use?

Santos, Ana Carolina Etrusco Zaroni / Sztajnbok, Jaques / Duarte-Neto, Amaro Nunes / Sousa, Amanda Freire Tamburini / Lopes, Alessandra Geisler Daud / Barrientos, Anna Carlota Mott

Revista do Instituto de Medicina Tropical de Sao Paulo

2020  Volume 62, Page(s) e78

Abstract: Disseminated tuberculosis is a severe disease with high-mortality that requires early diagnosis and treatment. Intestinal tuberculosis accounts for only 2% of tuberculosis cases worldwide and is extremely rare in children. We report a case of a 4-year- ... ...

Abstract Disseminated tuberculosis is a severe disease with high-mortality that requires early diagnosis and treatment. Intestinal tuberculosis accounts for only 2% of tuberculosis cases worldwide and is extremely rare in children. We report a case of a 4-year-old girl admitted due to disseminated tuberculosis with extensive intestinal involvement characterized by massive intestinal bleeding and hemorrhagic shock. The severity of the intestinal involvement precluded the exclusive use of oral anti-tuberculosis drugs and the patient was successfully treated with a combination of injectable and oral anti-tuberculosis agents. We discuss the importance of a regimen with injectable drugs for treating severe forms of tuberculosis in which the intestinal involvement impaired the use of oral drugs.
MeSH term(s) Antitubercular Agents/therapeutic use ; Child, Preschool ; Female ; Humans ; Pharmaceutical Preparations ; Tuberculosis/drug therapy
Chemical Substances Antitubercular Agents ; Pharmaceutical Preparations
Language English
Publishing date 2020-10-30
Publishing country Brazil
Document type Case Reports
ZDB-ID 128928-7
ISSN 1678-9946 ; 0036-4665
ISSN (online) 1678-9946
ISSN 0036-4665
DOI 10.1590/S1678-9946202062078
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