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Book ; Online ; E-Book: Environmental and food virology

Fongaro, Gislaine / Rodríguez-Lázaro, David / Souza, Doris Sobral Marques

impacts and challenges in one health approach

2023

Abstract: The active monitoring of pathogenic viruses and biomarkers of human and animal contamination in environmental and food matrices allows preventive surveillance and the discovery of new viruses and strains circulating in these populations, being an ... ...

Author's details	edited by Gislaine Fongaro, David Rodríguez-Lázaro, and Doris Sobral Marques Souza
Abstract	"The active monitoring of pathogenic viruses and biomarkers of human and animal contamination in environmental and food matrices allows preventive surveillance and the discovery of new viruses and strains circulating in these populations, being an important epidemiological and health control tool, since they represent major challenges in the fight against diseases, nutrition, and the world economy, negatively impacting the balance of One Health. In an unprecedented way, this book will address in up to 10 chapters each chapter is usually between 7,000 to 10,000 words and figures the themes related to 1 general characteristics of enteric viruses and environmental transmission with a focus on their structures, behavior and stability, 2 viruses as contaminants and bioindicators sanitary in environmental samples for the purposes of epidemiological monitoring and control, 3 tools applied to viral concentration and detection from environmental and food samples; 4 enteric viruses and environmental micropollutants correlation and, 5 challenges in the control of environmental and food viruses to reduce microbiological risk"--
Keywords	Food/Microbiology
Subject code	910.5
Language	English
Size	1 online resource (205 pages)
Publisher	CRC Press
Publishing place	Boca Raton, FL
Document type	Book ; Online ; E-Book
Note	Includes index.
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
ISBN	1-00-326349-6 ; 1-003-26349-6 ; 1-000-91141-1 ; 1-03-220419-2 ; 978-1-00-326349-4 ; 978-1-003-26349-4 ; 978-1-000-91141-1 ; 978-1-03-220419-2
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article: Prevalence, distribution and environmental effects on faecal indicator bacteria and pathogens of concern in commercial shellfish production areas in a subtropical region of a developing country (Santa Catarina, Brazil)

de Souza, Robson Ventura / Moresco, Vanessa / Miotto, Marilia / Souza, Doris Sobral Marques / de Campos, Carlos José Alexandre

Environmental monitoring and assessment. 2022 Apr., v. 194, no. 4

2022

Abstract: This paper reviews recent literature on the abundance and distribution of faecal indicator bacteria and pathogens in shellfish production areas in the state of Santa Catarina, on the subtropical coast of Brazil. This state supplies > 95% of the national ... ...

Abstract	This paper reviews recent literature on the abundance and distribution of faecal indicator bacteria and pathogens in shellfish production areas in the state of Santa Catarina, on the subtropical coast of Brazil. This state supplies > 95% of the national production of shellfish. Microbiological monitoring data were mapped using GIS and the results compared with those from other countries. Coastal human population is the main predictive parameter for faecal bacteria in the production areas. Temporal variations of the bacteria can also be predicted by solar radiation and rainfall. The prevalence of pathogens such as hepatitis A virus, human norovirus, Salmonella spp. and Vibrio spp. does not differ substantially from that in developed countries. The information reported here can be used to inform development of microbiological risk profiles for shellfish production areas.
Keywords	Hepatovirus A ; Norovirus ; Salmonella ; Vibrio ; coasts ; human population ; humans ; rain ; risk ; shellfish ; solar radiation ; subtropics ; Brazil
Language	English
Dates of publication	2022-04
Size	p. 286.
Publishing place	Springer International Publishing
Document type	Article
Note	Review
ZDB-ID	782621-7
ISSN	1573-2959 ; 0167-6369
ISSN (online)	1573-2959
ISSN	0167-6369
DOI	10.1007/s10661-022-09950-5
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Article ; Online: Bioaccumulation Dynamic by Crassostrea gigas Oysters of Viruses That Are Proposed as Surrogates for Enteric Virus Contamination in Environmental Samples

da Silva, Vilaine Corrêa / Elois, Mariana / Savi, Beatriz Pereira / Miotto, Marília / De Dea Lindner, Juliano / Fongaro, Gislaine / Souza, Doris Sobral Marques

Food Environ Virol. 2023 Mar., v. 15, no. 1 p.1-7

2023

Abstract: Oysters are filter-feeders and retain sewage-derived pathogens in their organs or tissues. Since most enteric viruses involved in outbreaks cannot grow in cell culture, studies using viral surrogate models are essential. Some species are proposed as ... ...

Abstract	Oysters are filter-feeders and retain sewage-derived pathogens in their organs or tissues. Since most enteric viruses involved in outbreaks cannot grow in cell culture, studies using viral surrogate models are essential. Some species are proposed as surrogates for enteric viruses in environmental samples, including in bivalve mollusk samples, such as murine norovirus type 1 (MNV-1) and somatic (as φX) or F-specific coliphages (as MS2) bacteriophages. This study evaluated the tissue distribution of viral surrogates for enteric virus contamination after their bioaccumulation by Crassostrea gigas. Oyster tissues were analyzed for the distribution of viral surrogates (MNV-1, φX-174, and MS2) in digestive tissue (DT), gills (GL), and mantle (MT) after 4, 6, and 24 h of experimental bioaccumulation. MNV-1 had higher counts at 6 h in DT (1.2 × 10³ PFU/g), followed by GL and MT (9.5 × 10² and 3.8 × 10² PFU/g, respectively). The bacteriophage φX-174 had a higher concentration in the MT at 4 and 6 h (3.0 × 10² PFU/g, in both) and MS2 in the GL after 24 h (2.2 × 10² PFU/g). The bioaccumulation pattern of MNV-1 by oysters was similar to the other enteric viruses (more in DT), while that of phages followed distinct patterns from these. Since the MNV-1 is bioaccumulated by C. gigas and is adapted to grow in cell culture, it is an important tool for bioaccumulation and viral inactivation tests in oysters. Although bacteriophage bioaccumulation was not similar to enteric viruses, they can be indicated for viral bioaccumulation analysis, analyzing MT and GL, since they do not bioaccumulate in DT.
Keywords	Crassostrea gigas ; bioaccumulation ; cell culture ; coliphages ; mice ; tissue distribution
Language	English
Dates of publication	2023-03
Size	p. 1-7.
Publishing place	Springer US
Document type	Article ; Online
ZDB-ID	2487173-4
ISSN	1867-0342 ; 1867-0334
ISSN (online)	1867-0342
ISSN	1867-0334
DOI	10.1007/s12560-022-09538-9
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Article ; Online: Prevalence, distribution and environmental effects on faecal indicator bacteria and pathogens of concern in commercial shellfish production areas in a subtropical region of a developing country (Santa Catarina, Brazil).

de Souza, Robson Ventura / Moresco, Vanessa / Miotto, Marilia / Souza, Doris Sobral Marques / de Campos, Carlos José Alexandre

Environmental monitoring and assessment

2022 Volume 194, Issue 4, Page(s) 286

Abstract	This paper reviews recent literature on the abundance and distribution of faecal indicator bacteria and pathogens in shellfish production areas in the state of Santa Catarina, on the subtropical coast of Brazil. This state supplies > 95% of the national production of shellfish. Microbiological monitoring data were mapped using GIS and the results compared with those from other countries. Coastal human population is the main predictive parameter for faecal bacteria in the production areas. Temporal variations of the bacteria can also be predicted by solar radiation and rainfall. The prevalence of pathogens such as hepatitis A virus, human norovirus, Salmonella spp. and Vibrio spp. does not differ substantially from that in developed countries. The information reported here can be used to inform development of microbiological risk profiles for shellfish production areas.
MeSH term(s)	Aquaculture ; Brazil ; Developing Countries ; Environment ; Environmental Monitoring/methods ; Feces/microbiology ; Humans ; Prevalence ; Shellfish/microbiology ; Shellfish/virology
Language	English
Publishing date	2022-03-18
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	782621-7
ISSN	1573-2959 ; 0167-6369
ISSN (online)	1573-2959
ISSN	0167-6369
DOI	10.1007/s10661-022-09950-5
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Bioaccumulation Dynamic by Crassostrea gigas Oysters of Viruses That Are Proposed as Surrogates for Enteric Virus Contamination in Environmental Samples.

da Silva, Vilaine Corrêa / Elois, Mariana / Savi, Beatriz Pereira / Miotto, Marília / De Dea Lindner, Juliano / Fongaro, Gislaine / Souza, Doris Sobral Marques

Food and environmental virology

2022 Volume 15, Issue 1, Page(s) 1–7

Abstract	Oysters are filter-feeders and retain sewage-derived pathogens in their organs or tissues. Since most enteric viruses involved in outbreaks cannot grow in cell culture, studies using viral surrogate models are essential. Some species are proposed as surrogates for enteric viruses in environmental samples, including in bivalve mollusk samples, such as murine norovirus type 1 (MNV-1) and somatic (as φX) or F-specific coliphages (as MS2) bacteriophages. This study evaluated the tissue distribution of viral surrogates for enteric virus contamination after their bioaccumulation by Crassostrea gigas. Oyster tissues were analyzed for the distribution of viral surrogates (MNV-1, φX-174, and MS2) in digestive tissue (DT), gills (GL), and mantle (MT) after 4, 6, and 24 h of experimental bioaccumulation. MNV-1 had higher counts at 6 h in DT (1.2 × 10
MeSH term(s)	Animals ; Mice ; Crassostrea ; Viruses ; Enterovirus/physiology ; Bacteriophages ; Norovirus/physiology
Language	English
Publishing date	2022-10-26
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2487173-4
ISSN	1867-0342 ; 1867-0334
ISSN (online)	1867-0342
ISSN	1867-0334
DOI	10.1007/s12560-022-09538-9
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Article ; Online: Viral uptake and stability in Crassostrea gigas oysters during depuration, storage and steaming.

Pilotto, Mariana Rangel / Souza, Doris Sobral Marques / Barardi, Célia Regina Monte

Marine pollution bulletin

2019 Volume 149, Page(s) 110524

Abstract: More stable than bacteria in environmental samples, enteric viruses are generally related to outbreaks of gastroenteritis caused by the consumption of contaminated oysters. This study evaluated: i) the dynamic processes of enteric viral models ... ...

Abstract	More stable than bacteria in environmental samples, enteric viruses are generally related to outbreaks of gastroenteritis caused by the consumption of contaminated oysters. This study evaluated: i) the dynamic processes of enteric viral models bioaccumulation by Crassostrea gigas oysters artificially contaminated; ii) the stability of these viruses in oysters in controlled temperature conditions and iii) the effect of UV light in inactivating these viruses in depurated oysters. Plaque assay (PA) was used to assess the infectivity of both viral models. Cell culture coupled with RT-qPCR (ICC-RT-qPCR) was used to measure infectious adenovirus type 2 (HAdV-2) genomes and qPCR to measure genome copies of murine norovirus (MNV-1). The virus uptake through bioaccumulation behave differently: HAdV-2 reached its peak of uptake faster than MNV-1. Both viruses showed high stability in oysters when maintained under 4 °C, but were completely inactivated in steamed oysters. The HAdV-2 was completely inactivated after 12 h of depuration with UV light and after 24 h without UV light. After 72 h of depuration, MNV-1 was still detected in both tanks, probably due to the stronger interaction of this virus with the oyster's tissues. This study demonstrated the importance of a secure depuration time in ensuring a clean and safe product, and that the steaming process is the safest way to prepare oysters for consumption.
MeSH term(s)	A549 Cells ; Adenoviruses, Human/genetics ; Adenoviruses, Human/isolation & purification ; Animals ; Cooking ; Crassostrea/virology ; Food Microbiology ; Food Storage ; Humans ; Mice ; Norovirus/genetics ; Norovirus/isolation & purification ; Norovirus/pathogenicity ; RAW 264.7 Cells ; Real-Time Polymerase Chain Reaction ; Shellfish/virology ; Steam ; Temperature ; Ultraviolet Rays
Chemical Substances	Steam
Language	English
Publishing date	2019-09-05
Publishing country	England
Document type	Journal Article
ZDB-ID	2001296-2
ISSN	1879-3363 ; 0025-326X
ISSN (online)	1879-3363
ISSN	0025-326X
DOI	10.1016/j.marpolbul.2019.110524
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Article: Presence of enteric viruses, bioaccumulation and stability in Anomalocardia brasiliana clams (Gmelin, 1791)

Souza, Doris Sobral Marques / Ana Ferreira Ávila Dominot / Célia Regina Monte Barardi / Vanessa Moresco

International journal of food microbiology. 2018 Feb. 02, v. 266

2018

Abstract: Bivalve mollusks are filter feeders and may accumulate human pathogens in their tissues. Many studies demonstrated human diseases associated with bivalve consumption, especially oysters. Anomalocardia brasiliana clams are distributed along the Brazilian ... ...

Abstract	Bivalve mollusks are filter feeders and may accumulate human pathogens in their tissues. Many studies demonstrated human diseases associated with bivalve consumption, especially oysters. Anomalocardia brasiliana clams are distributed along the Brazilian coastal area and are an exotic ingredient for some typical dishes in Brazil. Even though there are several reports describing the contamination of oysters and mussels with human pathogens, there is a lack of studies reporting contamination of A. brasiliana with human pathogens. An evaluation of natural microbiological contamination in A. brasiliana samples over a period of 18months (November 2014 to April 2016) showed that the bacteria indices were in accordance with Brazilian regulations (E. coli<230MPN and Salmonella sp. absent in 25g of meat). However, the enteric viruses evaluated were detected throughout the analysis period, with the highest result for the hepatitis A virus (HAV); followed by Rotavirus-A (RVA); Human Adenovirus (HAdV) and Norovirus GI (NoV GI). The bioaccumulation of enteric viruses by A. brasiliana during a period of 24h was performed using NoV GI and GII, HAV, RVA and HAdV as models. Interestingly the mollusk demonstrated different uptake behaviors in relation to these viruses throughout the time period. NoV GI was the most adsorbed virus after 24h. HAV concentration was <1% at 3h, but it increased to <10% at 8h, remaining unchanged until 12h, and decreasing to <3% at 24h; HAdV reached its highest concentration at 12h, being released by the animals and lowering to <3% at 24h. RVA bioaccumulation was unstable over time, reaching its highest values after 24h (<5%); NoV GII bioaccumulation remained <1%. Thermal inactivation of HAdV-2 in A. brasiliana was also evaluated. After the usual gentle cooking procedure using different times (0, 1, 1.5, 3 and 5mins), viral infectivity was evaluated using ICC-et-RT-qPCR. The temperature inside the DT remained <80°C over time and after 5min of cooking the HAdV reached a decay of 90% (1 log10). The results showed a real warn to the consumers that can be exposed to infectious human viruses if they eat these clams improperly cooked. HAV was the most detected virus in these animals, which may lead to outbreaks. A. brasiliana exhibited distinct behavior in NoV GI bioaccumulation and persistence, pointing to the need for further studies about the cellular ligands used by these viruses to become attached to these clams.
Keywords	Adenoviridae ; bacteria ; bioaccumulation ; Bivalvia ; clams ; coasts ; cooking ; Escherichia coli ; heat inactivation ; Hepatitis A virus ; human diseases ; humans ; ingredients ; ligands ; meat ; models ; mussels ; Norovirus ; oysters ; pathogenicity ; Rotavirus A ; Salmonella ; temperature ; tissues ; vertebrate viruses ; viruses ; Brazil
Language	English
Dates of publication	2018-0202
Size	p. 363-371.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	87122-9
ISSN	1879-3460 ; 0168-1605
ISSN (online)	1879-3460
ISSN	0168-1605
DOI	10.1016/j.ijfoodmicro.2017.08.004
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: SARS-CoV-2 in Human Sewage and River Water from a Remote and Vulnerable Area as a Surveillance Tool in Brazil

Fongaro, Gislaine / Rogovski, Paula / Savi, Beatriz Pereira / Cadamuro, Rafael Dorighello / Pereira, Juliana Virgínia Faria / Anna, Iago Hashimoto Sant / Rodrigues, Ivan Henrique / Souza, Doris Sobral Marques / Saravia, Edgard Gregory Torres / Rodríguez-Lázaro, David / da Silva Lanna, Maria Célia

Food Environ Virol. 2022 Dec., v. 14, no. 4 p.417-420

2022

Abstract: In the present study, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was monitored in environmental samples from rural and vulnerable areas (a presidio, worker accommodation units, and river waters upstream and downstream of a rural ... ...

Abstract	In the present study, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was monitored in environmental samples from rural and vulnerable areas (a presidio, worker accommodation units, and river waters upstream and downstream of a rural community) from Minas Gerais State region, Southern Brazil, in August 2020. The sampling was performed prior to official declaration of the coronavirus disease (COVID-19) cases in those sites. SARS-CoV-2 RNA was detected in the presidio and workers accommodation units (3.0 × 10⁴ virus genome copies (GC)/mL and 4.3 × 10⁴ GC/mL of sewage, respectively). While SARS-CoV-2 was not detected in the river water upstream of the rural community, SARS-CoV-2 RNA was detected in downstream river waters (1.1 × 10² SARS-CoV-2 GC/mL). The results obtained in this study highlight the utility of SARS-CoV-2 monitoring in wastewater and human sewage as a non-invasive early warning tool to support health surveillance in vulnerable and remote areas, particularly in development countries.
Keywords	COVID-19 infection ; RNA ; Severe acute respiratory syndrome coronavirus 2 ; humans ; monitoring ; river water ; rivers ; rural communities ; sewage ; viral genome ; wastewater ; Brazil
Language	English
Dates of publication	2022-12
Size	p. 417-420.
Publishing place	Springer US
Document type	Article ; Online
ZDB-ID	2487173-4
ISSN	1867-0342 ; 1867-0334
ISSN (online)	1867-0342
ISSN	1867-0334
DOI	10.1007/s12560-021-09487-9
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Presence of enteric viruses, bioaccumulation and stability in Anomalocardia brasiliana clams (Gmelin, 1791).

Souza, Doris Sobral Marques / Dominot, Ana Ferreira Ávila / Moresco, Vanessa / Barardi, Célia Regina Monte

International journal of food microbiology

2017

Abstract	Bivalve mollusks are filter feeders and may accumulate human pathogens in their tissues. Many studies demonstrated human diseases associated with bivalve consumption, especially oysters. Anomalocardia brasiliana clams are distributed along the Brazilian coastal area and are an exotic ingredient for some typical dishes in Brazil. Even though there are several reports describing the contamination of oysters and mussels with human pathogens, there is a lack of studies reporting contamination of A. brasiliana with human pathogens. An evaluation of natural microbiological contamination in A. brasiliana samples over a period of 18months (November 2014 to April 2016) showed that the bacteria indices were in accordance with Brazilian regulations (E. coli<230MPN and Salmonella sp. absent in 25g of meat). However, the enteric viruses evaluated were detected throughout the analysis period, with the highest result for the hepatitis A virus (HAV); followed by Rotavirus-A (RVA); Human Adenovirus (HAdV) and Norovirus GI (NoV GI). The bioaccumulation of enteric viruses by A. brasiliana during a period of 24h was performed using NoV GI and GII, HAV, RVA and HAdV as models. Interestingly the mollusk demonstrated different uptake behaviors in relation to these viruses throughout the time period. NoV GI was the most adsorbed virus after 24h. HAV concentration was <1% at 3h, but it increased to <10% at 8h, remaining unchanged until 12h, and decreasing to <3% at 24h; HAdV reached its highest concentration at 12h, being released by the animals and lowering to <3% at 24h. RVA bioaccumulation was unstable over time, reaching its highest values after 24h (<5%); NoV GII bioaccumulation remained <1%. Thermal inactivation of HAdV-2 in A. brasiliana was also evaluated. After the usual gentle cooking procedure using different times (0, 1, 1.5, 3 and 5mins), viral infectivity was evaluated using ICC-et-RT-qPCR. The temperature inside the DT remained <80°C over time and after 5min of cooking the HAdV reached a decay of 90% (1 log
Language	English
Publishing date	2017-08-12
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	87122-9
ISSN	1879-3460 ; 0168-1605
ISSN (online)	1879-3460
ISSN	0168-1605
DOI	10.1016/j.ijfoodmicro.2017.08.004
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Article ; Online: SARS-CoV-2 in Human Sewage and River Water from a Remote and Vulnerable Area as a Surveillance Tool in Brazil.

Food and environmental virology

2021 Volume 14, Issue 4, Page(s) 417–420

Abstract	In the present study, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was monitored in environmental samples from rural and vulnerable areas (a presidio, worker accommodation units, and river waters upstream and downstream of a rural community) from Minas Gerais State region, Southern Brazil, in August 2020. The sampling was performed prior to official declaration of the coronavirus disease (COVID-19) cases in those sites. SARS-CoV-2 RNA was detected in the presidio and workers accommodation units (3.0 × 10
MeSH term(s)	Humans ; SARS-CoV-2/genetics ; Sewage ; RNA, Viral/genetics ; Brazil/epidemiology ; COVID-19/epidemiology ; Water
Chemical Substances	Sewage ; RNA, Viral ; Water (059QF0KO0R)
Language	English
Publishing date	2021-07-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	2487173-4
ISSN	1867-0342 ; 1867-0334
ISSN (online)	1867-0342
ISSN	1867-0334
DOI	10.1007/s12560-021-09487-9
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