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Article ; Online: Sars-CoV-2: A clinical update - II.

Cespedes, Mateus da Silveira / Souza, José Carlos Rosa Pires de

Revista da Associacao Medica Brasileira (1992)

2020 Volume 66, Issue 4, Page(s) 547–557

Abstract: Introduction: A covid-19 pandemic decreed by WHO has raised greater awareness of it.: Epidemiology: The infection, reached the mark of 2,000,000 patients in 33 countries and caused the risk of the presence of comorbidities and advanced age.: ... ...

Abstract	Introduction: A covid-19 pandemic decreed by WHO has raised greater awareness of it. Epidemiology: The infection, reached the mark of 2,000,000 patients in 33 countries and caused the risk of the presence of comorbidities and advanced age. Transmissibility: The transmissibility calculated so far is similar to the H1N1 epidemic, but with lower mortality rates. Physiopathology: The SARS-CoV-2 virus, of the Coronaviridae family, has the capacity for cellular invasion through the angiotensin-converting enzyme 2 does not have a lower respiratory epithelium and in the cells of the small intestine mucosa. Clinical manifestations: a presentation can be divided into mild (fever, fatigue, cough, myalgia, and sputum) and severe (cyanosis, dyspnoea, tachypnea, chest pain, hypoxemia and need for clinical measurement) and has an estimated estimate of 2%. Diagnosis: allows the detection of viral load in CRP-TR of patients with high clinical suspicion. Treatment: based on supportive measures and infection control. In severe cases, the use of medications such as hydroxychloroquine and azithromycin or medication can be promising. Take care to avoid the use of corticosteroids. There are no restrictions on the use of resources and IECAs / BRAs.
MeSH term(s)	Angiotensin-Converting Enzyme 2 ; Basic Reproduction Number ; Betacoronavirus ; COVID-19 ; Child ; Coronavirus Infections/diagnosis ; Coronavirus Infections/mortality ; Coronavirus Infections/physiopathology ; Coronavirus Infections/therapy ; Diagnosis, Differential ; Drug Therapy, Combination ; Humans ; Palliative Care/methods ; Pandemics ; Peptidyl-Dipeptidase A/metabolism ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/mortality ; Pneumonia, Viral/physiopathology ; Pneumonia, Viral/therapy ; SARS-CoV-2
Chemical Substances	Peptidyl-Dipeptidase A (EC 3.4.15.1) ; ACE2 protein, human (EC 3.4.17.23) ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23)
Keywords	covid19
Language	English
Publishing date	2020-06-22
Publishing country	Brazil
Document type	Journal Article ; Review
ZDB-ID	731969-1
ISSN	1806-9282 ; 0104-4230 ; 0004-5241 ; 0102-843X
ISSN (online)	1806-9282
ISSN	0104-4230 ; 0004-5241 ; 0102-843X
DOI	10.1590/1806-9282.66.4.547
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Article ; Online: Coronavirus: a clinical update of Covid-19.

Cespedes, Mateus da Silveira / Souza, José Carlos Rosa Pires de

Revista da Associacao Medica Brasileira (1992)

2020 Volume 66, Issue 2, Page(s) 116–123

Abstract: A covid-19 pandemic decreed by WHO has raised greater awareness of it. The infection reached the mark of 350,000 patients in 33 countries and affected as comorbidities the presence of comorbidities and advanced age. The transmissibility calculated so far ...

Abstract	A covid-19 pandemic decreed by WHO has raised greater awareness of it. The infection reached the mark of 350,000 patients in 33 countries and affected as comorbidities the presence of comorbidities and advanced age. The transmissibility calculated so far is similar to the H1N1 epidemic, but with lower mortality rates. The SARS-CoV-2 virus, of the Coronaviridae family, has the capacity for cellular invasion through the angiotensin-converting enzyme 2 does not have a lower respiratory epithelium and in the cells of the small intestine mucosa. A presentation can be divided into mild (fever, fatigue, cough, myalgia, and sputum) and severe (cyanosis, dyspnoea, tachypnea, chest pain, hypoxemia and need for clinical measurement) and has an estimated estimate of 2%.allows the detection of viral load in CRP-TR of patients with high clinical suspicion. Based on supportive measures and infection control. In severe cases, the use of medications such as hydroxychloroquine and azithromycin or medication can be promising. Take care to avoid the use of corticosteroids. There are no restrictions on the use of resources and ACEIs / ARBs.
MeSH term(s)	Betacoronavirus ; COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/therapy ; Coronavirus Infections/transmission ; Diagnosis, Differential ; Humans ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/therapy ; Pneumonia, Viral/transmission ; Risk Factors ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-05-15
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	731969-1
ISSN	1806-9282 ; 0104-4230 ; 0004-5241 ; 0102-843X
ISSN (online)	1806-9282
ISSN	0104-4230 ; 0004-5241 ; 0102-843X
DOI	10.1590/1806-9282.66.2.116
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Coronavirus

Cespedes, Mateus da Silveira / Souza, José Carlos Rosa Pires de

Revista da Associação Médica Brasileira v.66 n.2 2020

a clinical update of Covid-19

2020

Abstract: SUMMARY INTRODUCTION A covid-19 pandemic decreed by WHO has raised greater awareness of it. EPIDEMIOLOGY The infection reached the mark of 350,000 patients in 33 countries and affected as comorbidities the presence of comorbidities and advanced age. ... ...

Abstract	SUMMARY INTRODUCTION A covid-19 pandemic decreed by WHO has raised greater awareness of it. EPIDEMIOLOGY The infection reached the mark of 350,000 patients in 33 countries and affected as comorbidities the presence of comorbidities and advanced age. TRANSMISSIBILITY The transmissibility calculated so far is similar to the H1N1 epidemic, but with lower mortality rates. PHYSIOPATHOLOGY The SARS-CoV-2 virus, of the Coronaviridae family, has the capacity for cellular invasion through the angiotensin-converting enzyme 2 does not have a lower respiratory epithelium and in the cells of the small intestine mucosa. CLINICAL MANIFESTATIONS a presentation can be divided into mild (fever, fatigue, cough, myalgia, and sputum) and severe (cyanosis, dyspnoea, tachypnea, chest pain, hypoxemia and need for clinical measurement) and has an estimated estimate of 2%. DIAGNOSIS allows the detection of viral load in CRP-TR of patients with high clinical suspicion. TREATMENT based on supportive measures and infection control. In severe cases, the use of medications such as hydroxychloroquine and azithromycin or medication can be promising. Take care to avoid the use of corticosteroids. There are no restrictions on the use of resources and ACEIs / ARBs.
Keywords	coronavirus ; covid-19 ; SARS-CoV-2 ; pandemic ; update ; covid19
Subject code	610
Language	English
Publishing date	2020-02-01
Publisher	Associação Médica Brasileira
Publishing country	br
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Sars-CoV-2

Cespedes, Mateus da Silveira / Souza, José Carlos Rosa Pires de

Revista da Associação Médica Brasileira v.66 n.4 2020

A clinical update - II

2020

Abstract: SUMMARY INTRODUCTION A covid-19 pandemic decreed by WHO has raised greater awareness of it. EPIDEMIOLOGY The infection, reached the mark of 2,000,000 patients in 33 countries and caused the risk of the presence of comorbidities and advanced age. ... ...

Abstract	SUMMARY INTRODUCTION A covid-19 pandemic decreed by WHO has raised greater awareness of it. EPIDEMIOLOGY The infection, reached the mark of 2,000,000 patients in 33 countries and caused the risk of the presence of comorbidities and advanced age. TRANSMISSIBILITY The transmissibility calculated so far is similar to the H1N1 epidemic, but with lower mortality rates. PHYSIOPATHOLOGY The SARS-CoV-2 virus, of the Coronaviridae family, has the capacity for cellular invasion through the angiotensin-converting enzyme 2 does not have a lower respiratory epithelium and in the cells of the small intestine mucosa. CLINICAL MANIFESTATIONS a presentation can be divided into mild (fever, fatigue, cough, myalgia, and sputum) and severe (cyanosis, dyspnoea, tachypnea, chest pain, hypoxemia and need for clinical measurement) and has an estimated estimate of 2%. DIAGNOSIS allows the detection of viral load in CRP-TR of patients with high clinical suspicion. TREATMENT based on supportive measures and infection control. In severe cases, the use of medications such as hydroxychloroquine and azithromycin or medication can be promising. Take care to avoid the use of corticosteroids. There are no restrictions on the use of resources and IECAs / BRAs.
Keywords	Public health ; Coronavirus ; COVID-19 ; Pandemics ; Respiratory tract infections ; Review ; covid19
Subject code	610
Language	English
Publishing date	2020-04-01
Publisher	Associação Médica Brasileira
Publishing country	br
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Sars-CoV-2: A clinical update - II

Cespedes, Mateus da Silveira / Souza, Jose Carlos Rosa Pires de

Revista da Associacao Medica Brasileira (1992)

Abstract: INTRODUCTION: A covid-19 pandemic decreed by WHO has raised greater awareness of it EPIDEMIOLOGY: The infection, reached the mark of 2,000,000 patients in 33 countries and caused the risk of the presence of comorbidities and advanced age TRANSMISSIBILITY: ...

Abstract	INTRODUCTION: A covid-19 pandemic decreed by WHO has raised greater awareness of it EPIDEMIOLOGY: The infection, reached the mark of 2,000,000 patients in 33 countries and caused the risk of the presence of comorbidities and advanced age TRANSMISSIBILITY: The transmissibility calculated so far is similar to the H1N1 epidemic, but with lower mortality rates PHYSIOPATHOLOGY: The SARS-CoV-2 virus, of the Coronaviridae family, has the capacity for cellular invasion through the angiotensin-converting enzyme 2 does not have a lower respiratory epithelium and in the cells of the small intestine mucosa CLINICAL MANIFESTATIONS: a presentation can be divided into mild (fever, fatigue, cough, myalgia, and sputum) and severe (cyanosis, dyspnoea, tachypnea, chest pain, hypoxemia and need for clinical measurement) and has an estimated estimate of 2% DIAGNOSIS: allows the detection of viral load in CRP-TR of patients with high clinical suspicion TREATMENT: based on supportive measures and infection control In severe cases, the use of medications such as hydroxychloroquine and azithromycin or medication can be promising Take care to avoid the use of corticosteroids There are no restrictions on the use of resources and IECAs / BRAs
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #613693
Database	COVID19

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Article: Coronavirus: a clinical update of Covid-19

Cespedes, Mateus da Silveira / Souza, José Carlos Rosa Pires de

Rev Assoc Med Bras (1992)

Abstract	A covid-19 pandemic decreed by WHO has raised greater awareness of it. The infection reached the mark of 350,000 patients in 33 countries and affected as comorbidities the presence of comorbidities and advanced age. The transmissibility calculated so far is similar to the H1N1 epidemic, but with lower mortality rates. The SARS-CoV-2 virus, of the Coronaviridae family, has the capacity for cellular invasion through the angiotensin-converting enzyme 2 does not have a lower respiratory epithelium and in the cells of the small intestine mucosa. A presentation can be divided into mild (fever, fatigue, cough, myalgia, and sputum) and severe (cyanosis, dyspnoea, tachypnea, chest pain, hypoxemia and need for clinical measurement) and has an estimated estimate of 2%.allows the detection of viral load in CRP-TR of patients with high clinical suspicion. Based on supportive measures and infection control. In severe cases, the use of medications such as hydroxychloroquine and azithromycin or medication can be promising. Take care to avoid the use of corticosteroids. There are no restrictions on the use of resources and ACEIs / ARBs.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #32428144
Database	COVID19

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Article ; Online: Sleep and chronotype in university students in COVID-19 pandemic ; Sueño y cronotipo en estudiantes universitarios en pandemia COVID-19 ; Sono e cronotipo em estudantes universitários na pandemia da COVID-19

Monteiro, Bruno Massayuki Makimoto / Santos Neto, Carleon Nascimento / Souza, José Carlos Rosa Pires de

Research, Society and Development; Vol. 9 No. 9; e632997688 ; Research, Society and Development; Vol. 9 Núm. 9; e632997688 ; Research, Society and Development; v. 9 n. 9; e632997688 ; 2525-3409

2020

Abstract: Introduction: In order to perform its specific functions (e.g., hormone production, cellular homeostasis and immunology), it is essential that the hours of sleep are correct. However, this quantity and quality of sleep can be impaired by several factors, ...

Abstract	Introduction: In order to perform its specific functions (e.g., hormone production, cellular homeostasis and immunology), it is essential that the hours of sleep are correct. However, this quantity and quality of sleep can be impaired by several factors, such as psychological and environmental. Therefore, the objective was to investigate in the literature the sleep habits, chronotype and biological clock of university students in the current pandemic scenario of COVID-19. Methodology: A narrative bibliographic review was carried out with scientific articles published between 2010 and 2020 in the Cochrane, Embase, Web of Science, LILACS, Scielo, Pubmed, Sciencedirect databases; the descriptors were "sleep", "sleep disorders", "chronotype", "biological clock", "circadian rhythm", "morning", "evening", "students", "university students", "epidemics", "pandemics" , “COVID-19” and the Boolean “and”. Results and discussion: Making up the interactive complexity of sleep with the biological clock, are fluctuations, sensitivity, homeostasis, photopic and seasonal influence, pathology, body temperature, food, hormonal levels, immune system, psychological changes and physical activity. Consequently, many aspects related to the chronotype of young university students were altered and with prejudice to it, especially in view of the current stressful situation, which is the COVID-19 pandemic. Conclusion: Sleep and chronotype exert various physiological processes on the body of university students. This occurs in a non-linear and quite complex way; levels of cortisol, growth hormone, melatonin and fluctuations in body temperature were shown to be predictive and sensitive to changes in the sleep-wake process. Introducción: Para realizar sus funciones específicas (por ejemplo, producción de hormonas, homeostasis celular e inmunología), es fundamental que las horas de sueño sean las correctas. Sin embargo, esta cantidad y calidad de sueño puede verse afectada por varios factores, como el psicológico y el ambiental. Por tanto, el objetivo fue investigar en la literatura los hábitos de sueño, cronotipo y reloj biológico de los estudiantes universitarios en el actual escenario pandémico de COVID-19. Metodología: Se realizó una revisión bibliográfica narrativa con artículos científicos publicados entre 2010 y 2020 en las bases de datos Cochrane, Embase, Web of Science, LILACS, Scielo, Pubmed, Sciencedirect; los descriptores fueron "sueño", "trastornos del sueño", "cronotipo", "reloj biológico", "ciclo circadiano", "mañana", "tarde", "estudiantes", "estudiantes universitarios", "epidemias", "pandemias" , "COVID-19" y el booleano "e". Resultados y discusión: Componiendo la complejidad interactiva del sueño con el reloj biológico, se encuentran fluctuaciones, sensibilidad, homeostasis, influencia fotópica y estacional, patología, temperatura corporal, alimentación, niveles hormonales, sistema sistema inmunológico, cambios psicológicos y actividad física. Consecuentemente, muchos aspectos relacionados con el cronotipo de los jóvenes universitarios fueron alterados y con perjuicio del mismo, especialmente ante la situación estresante actual, que es la pandemia de COVID-19. Conclusión: El sueño y el cronotipo ejercen diversos procesos fisiológicos en el cuerpo de los estudiantes universitarios. Esto ocurre de una manera no lineal y bastante compleja; Los niveles de cortisol, hormona del crecimiento, melatonina y las fluctuaciones de la temperatura corporal demostraron ser predictivos y sensibles a los cambios en el proceso de sueño-vigilia. Introdução: Para que se possa desempenhar as suas funções específicas (e.g., produção de hormônios, homeostasia celular e imunologia), é fundamental que as horas de sono sejam corretas. Porém, essa quantidade e qualidade de sono pode ser prejudicada por diversos fatores, como psicológicos e ambientais. Portanto, objetivou-se investigar na literatura os hábitos de sono, cronotipo e relógio biológico dos estudantes universitários no atual cenário da pandemia da COVID-19. Metodologia: Fez-se uma revisão bibliográfica narrativa com artigos científicos publicados entre 2010 e 2020 nas bases de dados Cochrane, Embase, Web of Science, LILACS, Scielo, Pubmed, Sciencedirect; os descritores foram “sono”, “transtornos do sono”, “cronotipo”, “relógio biológico”, “ciclo circadiano”, “matutinidade”, “vespertinidade”, “estudantes”, “universitários”, “epidemias”, “pandemias”, “COVID-19” e o booleano “e”. Resultados e discussão: Compondo a complexidade interativa do sono com o relógio biológico, estão as flutuações, sensibilidade, homeostase, influência fotóptica e sazonal, patologia, temperatura corpórea, alimentação, níveis hormonais, sistema imune, alterações psicológicas e atividade física. Consequentemente, muitos de aspectos relacionados ao cronotipo dos jovens estudantes universitários mostraram-se alterados e com prejuízo ao mesmo, principalmente frente a atual situação estressora, em demasia, que é a pandemia da COVID-19. Conclusão: O sono e o cronotipo exercem variados processos fisiológicos no corpo dos estudantes universitários. Isto ocorre de forma não linear e bastante complexa; os níveis de cortisol, hormônio do crescimento, melatonina e as oscilações da temperatura corporal mostraram-se ser um caráter preditivo e sensível para alterações do processo sono-vigília.
Keywords	Sueño ; Estudiantes ; Universidades ; Ritmo Circadiano ; COVID-19 ; Sono ; Estudantes ; Sleep ; Students ; Universities ; Circadian Rhythm ; covid19
Language	Portuguese
Publishing date	2020-09-01
Publisher	Research, Society and Development
Publishing country	br
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Sleep habits in native brazilian bororo children

REIMÃO RUBENS / SOUZA JOSÉ CARLOS ROSA PIRES DE / GAUDIOSO CARLOS EDUARDO VILELA

Arquivos de Neuro-Psiquiatria, Vol 57, Iss 1, Pp 14-

1999 Volume 17

Abstract: Sleep behavior patterns in childhood are influenced by familial, cultural and environmental factors. In understanding sleep in Native Brazilian Bororo children, one should consider the influence of their culture on the child's sleep. This research ... ...

Abstract	Sleep behavior patterns in childhood are influenced by familial, cultural and environmental factors. In understanding sleep in Native Brazilian Bororo children, one should consider the influence of their culture on the child's sleep. This research analyzes sleep habits of Native Bororo children from the Meruri village, located in an Indian Reservation in the state of Mato Grosso. Fourty four children ( 24 M; 20 F) were evaluated; ages ranged from one month to 10 years, with a mean age of 4.9 years. Sleep characteristics were assessed by means of a standard questionnaire applied to the mothers. Cosleeping - sleeping together with family members - was a remarkable finding, in every child 0-2 year old and in 81.5% in the 2-10 years group. The second characteristic was sleeping with many people in the same room. There was an average of 5.1 people per room in the younger group and 3.9 people in the older group
Keywords	sleep ; sleep habits ; child ; cosleeping ; native Bororo indian ; Mato Grosso ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Neurology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Language	English
Publishing date	1999-01-01T00:00:00Z
Publisher	Academia Brasileira de Neurologia - ABNEURO
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Sleep habits in native Brazilian Terena children in the state of Mato Grosso do Sul, Brazil

REIMÃO RUBENS / SOUZA JOSÉ CARLOS ROSA PIRES DE / MEDEIROS MARIZÉLIA MAZZINI / ALMIRÃO RAQUEL ICASSATI

Arquivos de Neuro-Psiquiatria, Vol 56, Iss 4, Pp 703-

1998 Volume 707

Abstract: Sleep habits in childhood vary in function of physiologcal factors.Cultural traits also influence sleep habits. This research evaluates sleep habits of Native Brazilian Terena children. The Terena group here studied live in the central region of Mato ... ...

Abstract	Sleep habits in childhood vary in function of physiologcal factors.Cultural traits also influence sleep habits. This research evaluates sleep habits of Native Brazilian Terena children. The Terena group here studied live in the central region of Mato Grosso do Sul, Brazil, on the plains; they are peaceful and dedicated mainly to agriculture. Two villages were studied, Tereré and Córrego do Meio, both in Reservations. Sleep characteristics of 67 children (40M;27F), 2 to 10 year olds, were evaluated in interviews with their mothers. The results evidenced that cosleeping, in the same bed with family members is the standard Terena pattern present in every evaluated child. The presence of two or more beds and a mean of five or more people in each bedroom was the typical finding. The authors propose that cosleeping and the presence of numerous family members reflect the high values attributed to family links in the Terena culture.
Keywords	sleep ; sleep habits ; child ; native ; indian ; Terena ; cosleeping ; Mato Grosso do Sul - Brazil ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Neurology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Language	English
Publishing date	1998-01-01T00:00:00Z
Publisher	Academia Brasileira de Neurologia - ABNEURO
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Sleep characteristics in children in the isolated rural African-Brazilian descendant community of Furnas do Dionísio, State of Mato Grosso do Sul, Brazil

REIMÃO RUBENS / SOUZA JOSÉ CARLOS ROSA PIRES DE / GAUDIOSO CARLOS EDUARDO VILELA / GUERRA HELLEN DA COSTA / ALVES ANDREA DAS CHAGAS / OLIVEIRA JOLENE CRISTINA FERREIRA / GNOBIE NILTON CEZAR ANTÔNIO / SILVÉRIO DESIRÉE CORREA GUERRA

Arquivos de Neuro-Psiquiatria, Vol 57, Iss 3A, Pp 556-

1999 Volume 560

Abstract: Developmental and cultural factors affect sleep habits in childhood. The objective of this research was to determine sleep habits of children in the isolated rural African-Brazilian community of Furnas do Dionísio, Mato Grosso do Sul, Brazil. The members ...

Abstract	Developmental and cultural factors affect sleep habits in childhood. The objective of this research was to determine sleep habits of children in the isolated rural African-Brazilian community of Furnas do Dionísio, Mato Grosso do Sul, Brazil. The members of this community are closely related descendants of the ex-slave Dionísio, and remained in relative geographical isolation for about a century. Sleep characteristics of 55 children (35M; 20F), 2 to 10 year olds, were evaluated in interviews with their mothers. The results showed that cosleeping, in the same bed with family members, was present in 80.0% of the 2-3 year olds; decreasing to 25.0% of the 8-10 year olds. Only 5.4% of the children slept alone in their own bedroom. Mean number of persons per bedroom was 2.8. Only 7.0% of the bedrooms had TV; 98.1% slept in silence. The data obtained support the need to weigh cultural factors influence on sleep.
Keywords	sleep ; sleep habits ; child ; African-Brazilian ; Negro ; Black ; Furnas do Dionísio ; Mato Grosso do Sul ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Neurology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Language	English
Publishing date	1999-01-01T00:00:00Z
Publisher	Academia Brasileira de Neurologia - ABNEURO
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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