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  1. Book ; Online: Mobile ASP.NET MVC 5

    Sowell, Eric

    2013  

    Abstract: Mobile ASP.NET MVC 5 will take you step-by-step through the process of developing fluid content that adapts its layout to the client device using HTML, JavaScript and CSS, and responsive web design. This book introduces server-side techniques that allow ... ...

    Author's details by Eric Sowell
    Abstract Mobile ASP.NET MVC 5 will take you step-by-step through the process of developing fluid content that adapts its layout to the client device using HTML, JavaScript and CSS, and responsive web design. This book introduces server-side techniques that allow you to show different content to different devices and make the most of their strengths and capabilities. Mobile ASP.NET MVC 5 includes a wide range of techniques, tips, and guidelines for dealing with some of the challenges of mobile web development, such as browser incompatibilities, varying device performance, and targeting older devices. You’ll learn to: Use responsive principles to build apps that display and perform well on a range of mobile devices. Leverage your server-side code to customize what you serve to the client, depending on its capabilities. Build an ASP.NET MVC custom view engine, use display modes effectively, and create reusable mobile components with custom HTML helpers. Make the most of new capabilities offered on some devices by interacting with native APIs. By the end of Mobile ASP.NET MVC 5, you should feel confident building web apps that successfully target anything from an iOS or Android device to a feature phone or an older mobile browser. Along the way, you'll learn about the modern mobile web landscape and how to choose the approaches that are right for you, depending on your target audience. This book is for the ASP.NET developer who knows how ASP.NET MVC works and is eager to learn how to use it for building mobile websites
    Keywords Computer science ; Computer Einsteiger / Grundlagen
    Language English
    Size Online-Ressource (400 p), online resource
    Publisher Apress
    Publishing place Berkeley, CA ;s.l
    Document type Book ; Online
    Note Description based upon print version of record
    ISBN 9781430250562 ; 9781430250579 ; 1430250569 ; 1430250577
    DOI 10.1007/978-1-4302-5057-9
    Database Former special subject collection: coastal and deep sea fishing

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  2. Book: Mobile ASP.NET MVC 5

    Sowell, Eric

    2013  

    Author's details by Eric Sowell
    Keywords Microsoft .NET Framework ; Mobile computing
    Language English
    Publisher Apress
    Publishing place Berkeley, CA ;s.l
    Document type Book
    ISBN 9781430250562 ; 9781430250579 ; 1430250569 ; 1430250577
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  3. Book ; Online: Mobile ASP.NET MVC 5

    Sowell, Eric

    2013  

    Abstract: Mobile ASP.NET MVC 5 will take you step-by-step through the process of developing fluid content that adapts its layout to the client device using HTML, JavaScript and CSS, and responsive web design. This book introduces server-side techniques that allow ... ...

    Author's details by Eric Sowell
    Abstract Mobile ASP.NET MVC 5 will take you step-by-step through the process of developing fluid content that adapts its layout to the client device using HTML, JavaScript and CSS, and responsive web design. This book introduces server-side techniques that allow you to show different content to different devices and make the most of their strengths and capabilities. Mobile ASP.NET MVC 5 includes a wide range of techniques, tips, and guidelines for dealing with some of the challenges of mobile web development, such as browser incompatibilities, varying device performance, and targeting older devices. You’ll learn to: Use responsive principles to build apps that display and perform well on a range of mobile devices. Leverage your server-side code to customize what you serve to the client, depending on its capabilities. Build an ASP.NET MVC custom view engine, use display modes effectively, and create reusable mobile components with custom HTML helpers. Make the most of new capabilities offered on some devices by interacting with native APIs. By the end of Mobile ASP.NET MVC 5, you should feel confident building web apps that successfully target anything from an iOS or Android device to a feature phone or an older mobile browser. Along the way, you'll learn about the modern mobile web landscape and how to choose the approaches that are right for you, depending on your target audience. This book is for the ASP.NET developer who knows how ASP.NET MVC works and is eager to learn how to use it for building mobile websites
    Keywords Computer science ; Computer Einsteiger / Grundlagen
    Language English
    Size Online-Ressource (400 p), online resource
    Publisher Apress
    Publishing place Berkeley, CA ;s.l
    Document type Book ; Online
    Note Description based upon print version of record
    ISBN 9781430250562 ; 9781430250579 ; 1430250569 ; 1430250577
    DOI 10.1007/978-1-4302-5057-9
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  4. Article ; Online: Polymorphisms in the choline transporter SLC44A1 are associated with reduced cognitive performance in normotypic but not prenatal alcohol-exposed children.

    Smith, Susan M / Weathers, Torri D / Virdee, Manjot S / Schwantes-An, Tae-Hwi / Voruganti, Venkata Saroja / Mattson, Sarah N / Coles, Claire D / Kable, Julie A / Sowell, Elizabeth / Wozniak, Jeffrey R / Wetherill, Leah

    The American journal of clinical nutrition

    2023  Volume 119, Issue 1, Page(s) 117–126

    Abstract: Background: Choline is essential for healthy cognitive development. Single nucleotide polymorphisms (SNPs; rs3199966(G), rs2771040(G)) within the choline transporter SLC44A1 increase risk for choline deficiency. In a choline intervention trial of ... ...

    Abstract Background: Choline is essential for healthy cognitive development. Single nucleotide polymorphisms (SNPs; rs3199966(G), rs2771040(G)) within the choline transporter SLC44A1 increase risk for choline deficiency. In a choline intervention trial of children who experienced prenatal alcohol exposure (PAE), these alleles are associated with improved cognition.
    Objective: This study aimed to determine if SNPs within SLC44A1 are differentially associated with cognition in children with PAE compared with normotypic controls (genotype × exposure). A secondary objective tested for an association of these SNPs and cognition in controls (genotype-only).
    Design: This is a secondary analysis of data from the Collaborative Initiative on Fetal Alcohol Spectrum Disorders. Participants (163 normotypic controls, 162 PAE) underwent psychological assessments and were genotyped within SLC44A1. Choline status was not assessed. Association analysis between genotype × exposure was performed using an additive genetic model and linear regression to identify the allelic effect. The primary outcome was the interaction between SLC44A1 genotype × exposure status with respect to cognition. The secondary outcome was the cognitive-genotype association in normotypic controls.
    Results: Genotype × exposure analysis identified 7 SNPs in SLC44A1, including rs3199966(G) and rs2771040(G), and in strong linkage (D' ≥ 0.87), that were associated (adjusted P ≤ 0.05) with reduced performance in measures of general cognition, nonverbal and quantitative reasoning, memory, and executive function (β, 1.92-3.91). In controls, carriers of rs3199966(GT or GG) had worsened cognitive performance than rs3199966(TT) carriers (β, 0.46-0.83; P < 0.0001), whereas cognitive performance did not differ by rs3199966 genotype in those with PAE.
    Conclusions: Two functional alleles that increase vulnerability to choline deficiency, rs3199966(G) (Ser644Ala) and rs2771040(G) (3' untranslated region), are associated with worsened cognition in otherwise normotypic children. These alleles were previously associated with greater cognitive improvement in children with PAE who received supplemental choline. The findings endorse that choline benefits cognitive development in normotypic children and those with PAE.
    MeSH term(s) Child ; Humans ; Pregnancy ; Female ; Choline Deficiency ; Prenatal Exposure Delayed Effects/genetics ; Choline ; Fetal Alcohol Spectrum Disorders ; Cognition ; Antigens, CD ; Organic Cation Transport Proteins
    Chemical Substances choline transporter ; Choline (N91BDP6H0X) ; SLC44A1 protein, human ; Antigens, CD ; Organic Cation Transport Proteins
    Language English
    Publishing date 2023-11-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 280048-2
    ISSN 1938-3207 ; 0002-9165
    ISSN (online) 1938-3207
    ISSN 0002-9165
    DOI 10.1016/j.ajcnut.2023.10.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Sex differences in associations between white matter microstructure and gonadal hormones in children and adolescents with prenatal alcohol exposure.

    Uban, K A / Herting, M M / Wozniak, J R / Sowell, E R

    Psychoneuroendocrinology

    2017  Volume 83, Page(s) 111–121

    Abstract: Despite accumulating evidence from animal models demonstrating that prenatal alcohol exposure (PAE) results in life-long neuroendocrine dysregulation, very little is known on this topic among humans with fetal alcohol spectrum disorders (FASD). We ... ...

    Abstract Despite accumulating evidence from animal models demonstrating that prenatal alcohol exposure (PAE) results in life-long neuroendocrine dysregulation, very little is known on this topic among humans with fetal alcohol spectrum disorders (FASD). We expected that alterations in gonadal hormones might interfere with the typical development of white matter (WM) myelination, and in a sex-dependent manner, in human adolescents with FASD. In order to investigate this hypothesis, we used diffusion tensor imaging (DTI) to assess: 1) whether or not sex moderates the impact of PAE on WM microstructure; and 2) how gonadal hormones relate to alterations in WM microstructure in children and adolescents affected by PAE.
    Methods: 61 youth (9 to 16 yrs.; 49% girls; 50% PAE) participated as part of the Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD). DTI scans and passive drool samples were obtained to examine neurodevelopmental associations with testosterone (T) and dehydroepiandrosterone (DHEA) levels in boys and girls, and estradiol (E2) and progesterone (P) levels in girls. Tract-based spatial statistics were utilized to generate fractional anisotropy (FA) and mean diffusivity (MD) for 9 a priori WM regions of interest (ROIs).
    Results: As predicted, alterations in FA were observed in adolescents with PAE relative to controls, and these differences varied by sex. Girls with PAE exhibited lower FA (Inferior fronto-occipital and Uncinate fasciculi) while boys with PAE exhibited higher FA (Callosal body, Cingulum, Corticospinal tract, Optic radiation, Superior longitudinal fasciculus) relative to age-matched controls. When gonadal hormone levels were examined in relation to DTI measures, additional group differences in FA were revealed, demonstrating that neuroendocrine factors are associated with PAE-related brain alterations.
    Conclusions: These findings provide human evidence that PAE relates to sex-specific differences in WM microstructure, and underlying alterations in gonadal hormone function may, in part, contribute to these effects. Determining PAE-effects on neuroendocrine function among humans is an essential first step towards developing novel clinical (e.g., assessment or intervention) tools that target hormone systems to improve on-going brain development among children and adolescents with FASD.
    MeSH term(s) Abnormalities, Drug-Induced ; Adolescent ; Anisotropy ; Brain/drug effects ; Brain/growth & development ; Child ; Diffusion Tensor Imaging ; Ethanol/adverse effects ; Female ; Fetal Alcohol Spectrum Disorders/physiopathology ; Gonadal Hormones/analysis ; Gonadal Hormones/metabolism ; Humans ; Male ; Nerve Net/abnormalities ; Pregnancy ; Prenatal Exposure Delayed Effects/metabolism ; Saliva ; Sex Characteristics ; Sex Factors ; White Matter/abnormalities ; White Matter/pathology ; White Matter/ultrastructure
    Chemical Substances Gonadal Hormones ; Ethanol (3K9958V90M)
    Language English
    Publishing date 2017-05-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 197636-9
    ISSN 1873-3360 ; 0306-4530
    ISSN (online) 1873-3360
    ISSN 0306-4530
    DOI 10.1016/j.psyneuen.2017.05.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Diffusion tensor imaging studies of prenatal drug exposure: challenges of poly-drug use in pregnant women.

    Lebel, Catherine / Sowell, Elizabeth

    The Journal of pediatrics

    2011  Volume 159, Issue 5, Page(s) 709–710

    MeSH term(s) Cocaine/adverse effects ; Diffusion Tensor Imaging ; Exploratory Behavior ; Female ; Humans ; Impulsive Behavior ; Male ; Pregnancy ; Prenatal Exposure Delayed Effects ; Smoking/adverse effects
    Chemical Substances Cocaine (I5Y540LHVR)
    Language English
    Publishing date 2011-11
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2011.06.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Adolescent Brain Cognitive Development (ABCD) study Linked External Data (LED): Protocol and practices for geocoding and assignment of environmental data.

    Fan, Chun Chieh / Marshall, Andrew / Smolker, Harry / Gonzalez, Marybel R / Tapert, Susan F / Barch, Deanna M / Sowell, Elizabeth / Dowling, Gayathri J / Cardenas-Iniguez, Carlos / Ross, Jessica / Thompson, Wesley K / Herting, Megan M

    Developmental cognitive neuroscience

    2021  Volume 52, Page(s) 101030

    Abstract: Our brain is constantly shaped by our immediate environments, and while some effects are transient, some have long-term consequences. Therefore, it is critical to identify which environmental risks have evident and long-term impact on brain development. ... ...

    Abstract Our brain is constantly shaped by our immediate environments, and while some effects are transient, some have long-term consequences. Therefore, it is critical to identify which environmental risks have evident and long-term impact on brain development. To expand our understanding of the environmental context of each child, the Adolescent Brain Cognitive Development (ABCD) Study® incorporates the use of geospatial location data to capture a range of individual, neighborhood, and state level data based on the child's residential location in order to elucidate the physical environmental contexts in which today's youth are growing up. We review the major considerations and types of geocoded information incorporated by the Linked External Data Environmental (LED) workgroup to expand on the built and natural environmental constructs in the existing and future ABCD Study data releases. Understanding the environmental context of each youth furthers the consortium's mission to understand factors that may influence individual differences in brain development, providing the opportunity to inform public policy and health organization guidelines for child and adolescent health.
    MeSH term(s) Adolescent ; Adolescent Development ; Brain ; Child ; Cognition ; Geographic Mapping ; Humans ; Residence Characteristics
    Language English
    Publishing date 2021-11-08
    Publishing country Netherlands
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 2572271-2
    ISSN 1878-9307 ; 1878-9307
    ISSN (online) 1878-9307
    ISSN 1878-9307
    DOI 10.1016/j.dcn.2021.101030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: A Riemannian Framework for Linear and Quadratic Discriminant Analysis on the Tangent Space of Shapes.

    Pal, Susovan / Woods, Roger P / Panjiyar, Suchit / Sowell, Elizabeth / Narr, Katherine L / Joshi, Shantanu H

    Conference on Computer Vision and Pattern Recognition Workshops. IEEE Computer Society Conference on Computer Vision and Pattern Recognition. Workshops

    2017  Volume 2017, Page(s) 726–734

    Abstract: We present a Riemannian framework for linear and quadratic discriminant classification on the tangent plane of the shape space of curves. The shape space is infinite dimensional and is constructed out of square root velocity functions of curves. We ... ...

    Abstract We present a Riemannian framework for linear and quadratic discriminant classification on the tangent plane of the shape space of curves. The shape space is infinite dimensional and is constructed out of square root velocity functions of curves. We introduce the notion of mean and covariance of shape-valued random variables and samples from a tangent space to the pre-shapes (invariant to translation and scaling) and then extend it to the full shape space (rotational invariance). The shape observations from the population are approximated by coefficients of a Fourier basis of the tangent space. The algorithms for linear and quadratic discriminant analysis are then defined using reduced dimensional features obtained by projecting the original shape observations on to the truncated Fourier basis. We show classification results on synthetic data and shapes of cortical sulci, corpus callosum curves, as well as facial midline curve profiles from patients with fetal alcohol syndrome (FAS).
    Language English
    Publishing date 2017-08-24
    Publishing country United States
    Document type Journal Article
    ISSN 2160-7508
    ISSN 2160-7508
    DOI 10.1109/CVPRW.2017.102
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Remake Rates for Single-Unit Crowns in Clinical Practice: Findings from The National Dental Practice-Based Research Network.

    McCracken, Michael S / Litaker, Mark S / Gordan, Valeria V / Karr, Thomas / Sowell, Ellen / Gilbert, Gregg H

    Journal of prosthodontics : official journal of the American College of Prosthodontists

    2018  Volume 28, Issue 2, Page(s) 122–130

    Abstract: Purpose: Some crowns returned from the laboratory are clinically unacceptable, and dentists must remake them. The objectives of this study were to: (1) quantify the remake rate of single-unit crowns; and (2) identify factors significantly associated ... ...

    Abstract Purpose: Some crowns returned from the laboratory are clinically unacceptable, and dentists must remake them. The objectives of this study were to: (1) quantify the remake rate of single-unit crowns; and (2) identify factors significantly associated with crown remakes and intraoral fit.
    Materials and methods: Dentists participating in the National Dental Practice-Based Research Network recruited patients needing crowns and documented fabrication techniques, patient characteristics, and outcomes. Crowns were considered clinically acceptable or rejected. Also, various aspects of the clinical fit of the crown were graded and categorized as 'Goodness of Fit (GOF).' Dentist and patient characteristics were tested statistically for associations with crown acceptability and GOF.
    Results: More than 200 dentists participated in this study (N = 205) and evaluated 3750 single-unit crowns. The mean age (years) of patients receiving a crown was 55. The remake rate for crowns was 3.8%. The range of rejection rates among individual practitioners was 0% to 42%. Most clinicians (118, or 58%) did not reject any crowns; all rejections came from 42% of the clinicians (n = 87). The most common reasons for rejections were proximal misfit, marginal errors, and esthetic failures. Fewer years in practice was significantly associated with lower crown success rates and lower fit scores. GOF was also associated with practice busyness and patient insurance status, patient gender (dentists reported better fit for female patients), and patient ethnicity.
    Conclusions: The crown remake rate in this study was about 4%. Remakes and crown GOF were associated with certain dentist and practice characteristics.
    MeSH term(s) Crowns ; Decision Making ; Dental Prosthesis Design ; Esthetics, Dental ; Female ; Humans ; Male ; Middle Aged ; Practice Patterns, Dentists'/statistics & numerical data ; Prospective Studies ; Surveys and Questionnaires ; United States
    Language English
    Publishing date 2018-11-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1197213-0
    ISSN 1532-849X ; 1059-941X
    ISSN (online) 1532-849X
    ISSN 1059-941X
    DOI 10.1111/jopr.12995
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Resilience to COVID-19: Socioeconomic Disadvantage Associated With Higher Positive Parent-youth Communication and Youth Disease-prevention Behavior.

    Marshall, Andrew / Hackman, Daniel / Baker, Fiona / Breslin, Florence / Brown, Sandra / Dick, Anthony / Gonzalez, Marybel / Guillaume, Mathieu / Kiss, Orsolya / Lisdahl, Krista / McCabe, Connor / Pelham, William / Sheth, Chandni / Tapert, Susan / Van Rinsveld, Amandine / Wade, Natasha / Sowell, Elizabeth

    Research square

    2021  

    Abstract: Socioeconomic disadvantage is associated with larger COVID-19 disease burdens and pandemic-related economic impacts. We utilized the longitudinal Adolescent Brain Cognitive Development Study to understand how family- and neighborhood-level socioeconomic ... ...

    Abstract Socioeconomic disadvantage is associated with larger COVID-19 disease burdens and pandemic-related economic impacts. We utilized the longitudinal Adolescent Brain Cognitive Development Study to understand how family- and neighborhood-level socioeconomic disadvantage relate to disease burden, family communication, and preventative responses to the pandemic in over 6,000 youth-parent/caregiver dyads. Data were collected at three timepoints (May to August 2020). Here, we show that both family- and neighborhood-level disadvantage were associated with parents’ reports of greater family COVID-19 exposure risk and diagnoses, less perceived exposure risk, more frequent parent-youth conversations about COVID-19 risk/prevention and reassurance, and greater youth preventative behaviors. More disadvantaged families may be adaptively incorporating more protective strategies to reduce emotional distress and likelihood of COVID-19 infection. The results highlight the importance of parent-youth communication and disease-preventative practices for buffering the economic and disease burdens of COVID-19, along with policies and programs that reduce these burdens for families with socioeconomic disadvantage.
    Language English
    Publishing date 2021-04-23
    Publishing country United States
    Document type Preprint
    DOI 10.21203/rs.3.rs-444161/v1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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