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Article ; Online: A

Claesen, Jan / Spagnolo, Jennifer B / Ramos, Stephany Flores / Kurita, Kenji L / Byrd, Allyson L / Aksenov, Alexander A / Melnik, Alexey V / Wong, Weng R / Wang, Shuo / Hernandez, Ryan D / Donia, Mohamed S / Dorrestein, Pieter C / Kong, Heidi H / Segre, Julia A / Linington, Roger G / Fischbach, Michael A / Lemon, Katherine P

Science translational medicine

2020  Volume 12, Issue 570

Abstract: The composition of the skin microbiota varies widely among individuals when sampled at the same body site. A key question is which molecular factors determine strain-level variability within sub-ecosystems of the skin microbiota. Here, we used a genomics- ...

Abstract The composition of the skin microbiota varies widely among individuals when sampled at the same body site. A key question is which molecular factors determine strain-level variability within sub-ecosystems of the skin microbiota. Here, we used a genomics-guided approach to identify an antibacterial biosynthetic gene cluster in
MeSH term(s) Anti-Bacterial Agents/pharmacology ; Hair Follicle ; Humans ; Microbiota ; Propionibacterium acnes ; Skin
Chemical Substances Anti-Bacterial Agents
Language English
Publishing date 2020-11-18
Publishing country United States
Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID 2518854-9
ISSN 1946-6242 ; 1946-6234
ISSN (online) 1946-6242
ISSN 1946-6234
DOI 10.1126/scitranslmed.aay5445
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