Article ; Online: Use of preprocurement biopsy in donation after circulatory death liver transplantation.
2022 Volume 28, Issue 11, Page(s) 1709–1715
Abstract: We perform routine preprocurement image-guided percutaneous liver biopsies on potential donation after circulatory death (DCD) liver donors. The purpose of this study was to examine the impact of preprocurement liver biopsy on the use of livers from DCD ... ...
| Abstract | We perform routine preprocurement image-guided percutaneous liver biopsies on potential donation after circulatory death (DCD) liver donors. The purpose of this study was to examine the impact of preprocurement liver biopsy on the use of livers from DCD donors. We retrospectively reviewed demographics, liver histology, and disposition of DCD liver donors within a single organ procurement organization (OPO) who underwent preprocurement liver biopsy from January 2000 through December 2019. A total of 212 potential donors underwent prerecovery biopsy. No donors were lost as a result of complications of biopsy. Of these, 183 (86.3%) had acceptable biopsies: 146 (79.8%) were successfully transplanted and 37 (20.2%) were deemed not suitable for transplant. In contrast, of 120 DCD livers recovered with the intent to transplant that were not biopsied prior to recovery, 59 (49.2%) were successfully transplanted, and 61 (50.8%) were deemed not suitable for transplant. A total of 14 donors were ruled out for transplant based on prerecovery histology. Successfully transplanted livers that underwent preprocurement biopsy were more likely to come from donors aged older than 50 years or with body mass index more than 30 kg/m |
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| MeSH term(s) | Aged ; Biopsy ; Death ; Graft Survival ; Humans ; Liver Transplantation/adverse effects ; Retrospective Studies ; Tissue Donors ; Tissue and Organ Procurement | |||||
| Language | English | |||||
| Publishing date | 2022-06-12 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 2006866-9 | |||||
| ISSN | 1527-6473 ; 1527-6465 | |||||
| ISSN (online) | 1527-6473 | |||||
| ISSN | 1527-6465 | |||||
| DOI | 10.1002/lt.26510 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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