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  1. Book ; Online: Air toxics exposure from vehicle emissions at a US border crossing

    Spengler, John

    Buffalo peace bridge study

    (Research report / Health Effects Institute ; 158)

    2011  

    Author's details John Spengler
    Series title Research report / Health Effects Institute ; 158
    Collection
    Language English
    Size XI, 148 S. : Ill., graph. Darst., Kt.
    Publisher Health Effects Inst
    Publishing place Boston, Mass
    Publishing country United States
    Document type Book ; Online
    HBZ-ID HT017588352
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Chronic household air pollution and exposure patterns among Himalayan nomads.

    Powers, Catlin I / Li, Linyan / Ezzati, Majid / Butler, James P / Zigler, Corwin M / Spengler, John D

    Journal of exposure science & environmental epidemiology

    2024  

    Abstract: Background: Household air pollution (HAP) is a major risk factor of non-communicable diseases, causing millions of premature deaths each year in developing nations. Populations living at high altitudes are particularly vulnerable to HAP and associated ... ...

    Abstract Background: Household air pollution (HAP) is a major risk factor of non-communicable diseases, causing millions of premature deaths each year in developing nations. Populations living at high altitudes are particularly vulnerable to HAP and associated health outcomes.
    Objectives: This study aims to explore the relationships between activity patterns, HAP, and an HAP biomarker among 100 Himalayan nomadic households during both cooking and heating-only periods.
    Methods: Household CO was monitored in 100 rural homes in Qinghai, China, at 3500 m on the Himalayan Plateau among Himalayan nomads. Carboxyhemoglobin (COHb) was used as a biomarker to assess exposure among 100 male and 100 female heads of household. Linear mixed-effects models were used to explore the relationship between COHb and activity patterns.
    Results: Cooking periods were associated with 7 times higher household CO concentrations compared with heating periods (94 ± 56 ppm and 13 ± 11 ppm, respectively). Over the three-day biomarker-monitoring period in each house, 99% of subjects had at least one COHb measurement exceeding the WHO safety level of 2%. Cooking was associated with a 32% increase in COHb (p < 0.001).
    Impact statement: This study on household air pollution (HAP) in high-altitude regions provides important insights into the exposure patterns of nomadic households in Qinghai, China. The study found that cooking is the primary factor influencing acute carbon monoxide (CO) exposure among women, while heating alone is sufficient to elevate CO exposure above WHO guidelines. The results suggest that cooking-only interventions have the potential to reduce HAP exposure among women, but solutions for both cooking and heating may be required to reduce COHb to below WHO guidelines. This study's findings may inform future interventions for fuel and stove selection to reduce HAP and exposure among other populations.
    Language English
    Publishing date 2024-03-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2218551-3
    ISSN 1559-064X ; 1559-0631
    ISSN (online) 1559-064X
    ISSN 1559-0631
    DOI 10.1038/s41370-024-00656-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Childhood pneumonia in Beijing: Associations and interactions among selected demographic and environmental factors.

    Qu, Fang / Weschler, Louise B / Zhang, Yinping / Spengler, John D

    Environmental research

    2023  Volume 231, Issue Pt 3, Page(s) 116211

    Abstract: Among infectious diseases, pneumonia is the greatest cause of mortality in children less than 5 years old. Approximately 27% of Beijing's 3-8 year-old children have had pneumonia at least once. The sole reservoir of pneumonia pathogens is the human ... ...

    Abstract Among infectious diseases, pneumonia is the greatest cause of mortality in children less than 5 years old. Approximately 27% of Beijing's 3-8 year-old children have had pneumonia at least once. The sole reservoir of pneumonia pathogens is the human nasopharynx. We investigated associations and interactions among two kinds of environmental risk factors: i) airborne pathogens, namely closed bedroom window and shared bedroom and ii) pollutants, namely traffic pollution and environmental tobacco smoke (ETS). We evaluated breastfeeding's (BF) protective value against childhood pneumonia. The database consists of responses to a questionnaire in a cross-sectional study. Crude and adjusted Odds Ratios were assessed independently for each risk factor. Combinations of the studied risk factors were analyzed using multivariate logistic regression. Risk factors were evaluated for interactions on the additive scale using the metrics Relative Excess Risk due to Interaction (RERI), Attributable Proportion (AP) and Synergy Index (S). All independent risk factors were significant for children's pneumonia. We also found evidence of possible synergistic interaction between pairs of risk factors that was stronger when one of the risk factors was a closed bedroom window. Remarkably, window opening was associated with reduced risk of pneumonia for children living near heavy traffic pollution. Longer duration BF was more protective than shorter, and exclusive BF was more protective than partial BF against childhood pneumonia. In conclusion, low ventilation (closed bedroom windows), shared bedroom, ETS, and traffic exposure were associated with increased risk of pneumonia. Exclusive BF for more than six months had the greatest protective value against pneumonia.
    MeSH term(s) Humans ; Child ; Child, Preschool ; Beijing/epidemiology ; Cross-Sectional Studies ; Risk Factors ; Tobacco Smoke Pollution/adverse effects ; Pneumonia/chemically induced ; Pneumonia/epidemiology ; Demography ; Environmental Exposure/analysis ; Air Pollutants
    Chemical Substances Tobacco Smoke Pollution ; Air Pollutants
    Language English
    Publishing date 2023-05-29
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2023.116211
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Childhood pneumonia in Beijing: Associations and interactions among selected demographic and environmental factors

    Qu, Fang / Weschler, Louise B. / Zhang, Yinping / Spengler, John D.

    Environmental Research. 2023 May 29, p.116211-

    2023  , Page(s) 116211–

    Abstract: Among infectious diseases, pneumonia is the greatest cause of mortality in children less than 5 years old. Approximately 27% of Beijing's 3-8 year-old children have had pneumonia at least once. The sole reservoir of pneumonia pathogens is the human ... ...

    Abstract Among infectious diseases, pneumonia is the greatest cause of mortality in children less than 5 years old. Approximately 27% of Beijing's 3-8 year-old children have had pneumonia at least once. The sole reservoir of pneumonia pathogens is the human nasopharynx. We investigated associations and interactions among two kinds of environmental risk factors: i) airborne pathogens, namely closed bedroom window and shared bedroom and ii) pollutants, namely traffic pollution and environmental tobacco smoke (ETS). We evaluated breastfeeding's (BF) protective value against childhood pneumonia. The database consists of responses to a questionnaire in a cross-sectional study. Crude and adjusted Odds Ratios were assessed independently for each risk factor. Combinations of the studied risk factors were analyzed using multivariate logistic regression. Risk factors were evaluated for interactions on the additive scale using the metrics Relative Excess Risk due to Interaction (RERI), Attributable Proportion (AP) and Synergy Index (S). All independent risk factors were significant for children's pneumonia. We also found evidence of possible synergistic interaction between pairs of risk factors that was stronger when one of the risk factors was a closed bedroom window. Remarkably, window opening was associated with reduced risk of pneumonia for children living near heavy traffic pollution. Longer duration BF was more protective than shorter, and exclusive BF was more protective than partial BF against childhood pneumonia. In conclusion, low ventilation (closed bedroom windows), shared bedroom, ETS, and traffic exposure were associated with increased risk of pneumonia. Exclusive BF for more than six months had the greatest protective value against pneumonia.
    Keywords breast feeding ; childhood ; cross-sectional studies ; databases ; humans ; mortality ; nasopharynx ; pneumonia ; pollution ; questionnaires ; regression analysis ; research ; risk factors ; risk reduction ; second hand smoke ; synergism ; traffic ; China ; Traffic related air pollution (TRAP) ; Breastfeeding ; Airborne pneumonia transmission ; Environmental tobacco smoke (ETS) ; Ventilation ; Bedroom crowding
    Language English
    Dates of publication 2023-0529
    Publishing place Elsevier Inc.
    Document type Article ; Online
    Note Pre-press version
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2023.116211
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: VENTILATION: WHY does no one take it seriously?

    Sundell, Jan / Spengler, John / Wargocki, Pawel

    Indoor air

    2021  Volume 31, Issue 3, Page(s) 605–607

    MeSH term(s) Air Pollution, Indoor ; Humans ; Respiration ; Ventilation
    Language English
    Publishing date 2021-04-20
    Publishing country England
    Document type Editorial
    ZDB-ID 1081722-0
    ISSN 1600-0668 ; 0905-6947
    ISSN (online) 1600-0668
    ISSN 0905-6947
    DOI 10.1111/ina.12824
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: In situ psycho-cognitive assessments support self-determined urban green exercise time.

    Tomasso, Linda Powers / Spengler, John D / Catalano, Paul J / Chen, Jarvis T / Laurent, Jose Guillermo Cedeño

    Urban forestry & urban greening

    2023  Volume 86

    Abstract: Prescribed nature walks frequently yield improvements to mood and cognition as observed in experimental studies. Research that uses real life settings such as self-determined time exercising outdoors for restorative health benefits may more accurately ... ...

    Abstract Prescribed nature walks frequently yield improvements to mood and cognition as observed in experimental studies. Research that uses real life settings such as self-determined time exercising outdoors for restorative health benefits may more accurately elicit effects than time-specified study protocols. This study examined in situ psycho-cognitive outcomes of routine walks in urban greenspace to test the concept that self-set exposure duration and not context alone is related to magnitude of psycho-cognitive benefit. Pre-post measurements taken on a diverse participant pool of individuals walking in urban parks and recruited on random days over a two-week period found significant associations between outdoor activity duration and cognitive and mood improvements. Greater outdoor walking duration linearly predicted stronger processing speeds but non-linearly in tests of other cognitive domains. Results of fixed effects model for mean mood change following green exercise show outdoor walking influenced mood change at highest levels of significance, even after accounting for individual level variability in duration. Mood improved for all durations of outdoor walking under a random effects model with high significance. Untethering fixed intervals of outdoor exercise from formal study design revealed briefer but more frequent nature engagement aligned with nature affinity. The influence of unmeasured factors, e.g., nature affinity or restorative conditioning, for prescriptive durations of urban green exercise merits further investigation toward designing wellbeing interventions directed at specific urban populations.
    Language English
    Publishing date 2023-06-17
    Publishing country Germany
    Document type Journal Article
    ISSN 1618-8667
    ISSN 1618-8667
    DOI 10.1016/j.ufug.2023.128005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: How does the presence of greenspace related to physical health issues in Indonesia?

    Asri, Aji Kusumaning / Lee, Hsiao-Yun / Wu, Chih-Da / Spengler, John D.

    Urban Forestry & Urban Greening. 2022 Aug., v. 74 p.127667-

    2022  

    Abstract: There have been many studies associating various aspects of greenspaces with physical health. Very few of these investigations are available for developing countries such as Indonesia. Our study focused on evaluating the association between greenspace ... ...

    Abstract There have been many studies associating various aspects of greenspaces with physical health. Very few of these investigations are available for developing countries such as Indonesia. Our study focused on evaluating the association between greenspace and the incidence rate of non-communicable diseases (NCDs) in terms of ischemic heart disease (IHD), diabetes mellitus (DM), rheumatoid arthritis (RA), and chronic kidney disease (CKD). Greenspace was presented by satellite-derived normalized difference vegetation index (NDVI) and forest-related green cover datasets to define exposures to the resolution of 250-m. The Institute for Health Metrics and Evaluation provided age and gender incident data of NCDs at the province level. A generalized additive mixed model coupled with sensitivity test was used to evaluate the exposure-outcome association. Stratified analyses were also employed. After adjusting for covariates, there was a significant negative association for incidence of NCDs and greenspace. We found that an interquartile unit increase of NDVI, and a percentage of forest were closely related to a decrease in the risk of NCDs by 0.3–9.4% and 0.6–6.2%, respectively. Stratified by exposure level, a greater effect of greenspace on reducing NCDs risk occurred in high exposure areas. Considering the socioeconomic factors, greenspace could influence on reducing NCD risks in high urbanization, low-high poverty, and low-high literacy areas. An increment unit of greenspace was associated with a decreased risk of NCDs. This study underscores important health benefits associated with exposures to nature supporting efforts to preserve greenspaces in Indonesia.
    Keywords data collection ; diabetes mellitus ; forests ; green infrastructure ; kidney diseases ; literacy ; myocardial ischemia ; normalized difference vegetation index ; physical health ; poverty ; rheumatoid arthritis ; risk ; risk reduction ; statistical models ; urban forestry ; urbanization ; Indonesia ; Chronic non-communicable diseases (NCDs) ; Developing country, greenspace ; Physical health diseases ; Socioeconomic factors
    Language English
    Dates of publication 2022-08
    Publishing place Elsevier GmbH
    Document type Article ; Online
    ISSN 1618-8667
    DOI 10.1016/j.ufug.2022.127667
    Database NAL-Catalogue (AGRICOLA)

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  8. Article: The risks of warm nights and wet days in the context of climate change: assessing road safety outcomes in Boston, USA and Santo Domingo, Dominican Republic.

    Nazif-Munoz, José Ignacio / Martínez, Pablo / Williams, Augusta / Spengler, John

    Injury epidemiology

    2021  Volume 8, Issue 1, Page(s) 47

    Abstract: Background: There remains a dearth of cross-city comparisons on the impact of climate change through extreme temperature and precipitation events on road safety. We examined trends in traffic fatalities, injuries and property damage associated with high ...

    Abstract Background: There remains a dearth of cross-city comparisons on the impact of climate change through extreme temperature and precipitation events on road safety. We examined trends in traffic fatalities, injuries and property damage associated with high temperatures and heavy rains in Boston (USA) and Santo Domingo (Dominican Republic).
    Methods: Official publicly available data on daily traffic outcomes and weather conditions during the warm season (May to September) were used for Boston (2002-2015) and Santo Domingo (2013-2017). Daily maximum temperatures and mean precipitations for each city were considered for classifying hot days, warm days, and warm nights, and wet, very wet, and extremely wet days. Time-series analyses were used to assess the relationship between temperature and precipitation and daily traffic outcomes, using a quasi-Poisson regression.
    Results: In Santo Domingo, the presence of a warm night increased traffic fatalities with a rate ratio (RR) of 1.31 (95% CI [confidence interval]: 1.00,1.71). In Boston, precipitation factors (particularly, extremely wet days) were associated with increments in traffic injuries (RR 1.25, 95% CI: 1.18, 1.32) and property damages (RR 1.42, 95% CI: 1.33, 1.51).
    Conclusion: During the warm season, mixed associations between weather conditions and traffic outcomes were found across Santo Domingo and Boston. In Boston, increases in heavy precipitation events were associated with higher traffic injuries and property damage. As climate change-related heavy precipitation events are projected to increase in the USA, the associations found in this study should be of interest for road safety planning in a rapidly changing environment.
    Language English
    Publishing date 2021-07-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2764253-7
    ISSN 2197-1714
    ISSN 2197-1714
    DOI 10.1186/s40621-021-00342-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Implications of disparities in social and built environment antecedents to adult nature engagement.

    Tomasso, Linda Powers / Cedeño Laurent, Jose Guillermo / Chen, Jarvis T / Spengler, John D

    PloS one

    2022  Volume 17, Issue 9, Page(s) e0274948

    Abstract: Antecedent factors which influence adult engagement with nature are underexplored given the human health benefits strongly associated with nature exposure. Formative pathways and impediments to nature contact merit understanding as they may contribute to ...

    Abstract Antecedent factors which influence adult engagement with nature are underexplored given the human health benefits strongly associated with nature exposure. Formative pathways and impediments to nature contact merit understanding as they may contribute to later-life health disparities. We probed experiential pathways and attitudes toward nature engagement among adults purposefully sampled across U.S. regions, age, race/ethnicity, and urbanicity through semi-structured focus group discussions. The research aims were to explore entryways and barriers to experiencing nature and learn how natured and built environments compete in influencing human-nature relationships. Sessions were recorded, transcribed, and analyzed following Braun and Clarke's phases of thematic analysis. Qualitative content analysis of discussions identified three principal themes: 1) formative influences promoting adult nature engagement (i.e., persons/organizations and places of origin), 2) detractors from nature engagement (i.e., perceptual, material, and physical barriers), and 3) role of current setting (i.e., natural and built environments) shaping nature-seeking relationships. We found experiential factors that included early life exposures outdoors, personal mentorship, and organizational affiliation to be highly influential in socializing individuals to nature and in soldering attachment to nature which manifests into adulthood. In contrast, changing demographics and childhood, inequity, social dynamics, metropolitan growth, urban renewal explained alienation from nature. These findings emphasize the importance of efforts to expand opportunities for nature contact, especially for youth living in economically challenged urban areas, which go beyond increasing greenspace to encompass mentoring partnerships for gaining skills and comfort outdoors and redesign of safe natured spaces within cities for hands-on learning and discovery.
    MeSH term(s) Adolescent ; Adult ; Attitude ; Built Environment ; Child ; Focus Groups ; Humans ; Mentoring ; Mentors
    Language English
    Publishing date 2022-09-23
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0274948
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Metals dust in workers' homes and potential for take home in the Greater Boston area: Pilot study.

    Ceballos, Diana M / Dong, Zhao / Peters, Junenette L / Herrick, Robert F / Gupta, Paridhi / Spengler, John D

    Environmental research

    2022  Volume 209, Page(s) 112893

    Abstract: Toxic metals such as lead, cadmium, arsenic, are present at construction worksites. From work, metals can easily, unintentionally be transported to homes of workers, contaminating living spaces and affecting others including children, known as "take-home ...

    Abstract Toxic metals such as lead, cadmium, arsenic, are present at construction worksites. From work, metals can easily, unintentionally be transported to homes of workers, contaminating living spaces and affecting others including children, known as "take-home exposure." Focus has been given to minimizing lead take-home exposure but less is known about other metals. This pilot study aims to better understand the sources and predictors of metals in the home primarily of construction workers (n = 21), but also explore other workers potentially exposed [janitorial (n = 4) and auto repair (n = 2) jobs]. Greater Boston workers were recruited in 2018-2019 through collaboration with community-based organizations and worker unions serving low-income/immigrant workers. During a home visit, a dust vacuum sample was collected, a worker questionnaire was administered, and home observations were performed to determine factors that could affect home metals concentration. Thirty elements were analyzed in the dust via inductively coupled plasma coupled to atomic emission and mass spectrometry. We performed univariable and multivariable models, potential predictive factors, and multivariable mixed-effect regression analyses combining metals. Arsenic, chromium, copper, lead, manganese, nickel, and tin, commonly found in construction, were higher in construction workers' home dust compared to other workers, although not statistically significant. Sociodemographic/work/home-related variables affected home metals dust concentrations. Various work-related factors were associated with higher metal dust levels, for example: no work locker vs. locker (nickel ratio of means or ROM = 4.2, p < 0.05); mixing vs. no mixing work/personal items (nickel ROM = 1.6, p < 0.05); dusty vs. no dusty at work (copper ROM = 3.1, p < 0.05); not washing vs. washing hands after work (manganese ROM = 1.4, p < 0.05); not changing vs. changing clothes after work (cadmium ROM = 6.9, p < 0.05; copper ROM = 3.6, p < 0.05). Mixed effect regression confirmed statistical significance, which suggests a likelihood of metal mixtures carrying a "take-home" potential. Lead home interventions should evaluate other metals exposure reduction.
    MeSH term(s) Boston ; Child ; Chromium/analysis ; Dust/analysis ; Humans ; Metals/analysis ; Occupational Exposure/analysis ; Pilot Projects
    Chemical Substances Dust ; Metals ; Chromium (0R0008Q3JB)
    Language English
    Publishing date 2022-02-05
    Publishing country Netherlands
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, N.I.H., Extramural
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2022.112893
    Database MEDical Literature Analysis and Retrieval System OnLINE

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