Article: Current and future strategies for prevention of neonatal early-onset group B streptococcus disease
Journal of Pediatric Infectious Diseases
2006 Volume 01, Issue 03, Page(s) 127–136
Abstract: Group B streptococci (GBS) have been recognized as a leading cause of serious early-onset neonatal sepsis for 30 years. Introduction of intrapartum antibiotic prophylaxis (IAP) has led to a decrease in neonatal early-onset GBS (EOGBS) disease and in ... ...
| Abstract | Group B streptococci (GBS) have been recognized as a leading cause of serious early-onset neonatal sepsis for 30 years. Introduction of intrapartum antibiotic prophylaxis (IAP) has led to a decrease in neonatal early-onset GBS (EOGBS) disease and in early neonatal sepsis-related mortality in many countries. At present decisions concerning the administration of IAP are usually based on either the presence of risk factors at the time of labor, or on screening of women at 35–37 weeks gestation. A new generation of rapid test for GBS suitable for point of care use offer the prospect of accurately detecting GBS during labor, which might improve targeting of IAP. Looking further ahead, active immunization of women before or during pregnancy may become the mainstay of prevention of neonatal EOGBS disease. In this article the role of GBS as a neonatal pathogen, and current and possible future strategies for prevention of neonatal EOGBS disease, are reviewed. |
|---|---|
| Keywords | Group B streptococcus ; neonatal infection ; prevention ; diagnosis |
| Language | English |
| Publishing date | 2006-09-01 |
| Publisher | Georg Thieme Verlag KG |
| Publishing place | Stuttgart ; New York |
| Document type | Article |
| ZDB-ID | 2236947-8 |
| ISSN | 1305-7693 ; 1305-7707 ; 1871-0336 |
| ISSN (online) | 1305-7693 |
| ISSN | 1305-7707 ; 1871-0336 |
| DOI | 10.1055/s-0035-1557080 |
| Database | Thieme publisher's database |
More links
Kategorien
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.