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Article ; Online: A Case of a Perinatal Woman on Methadone Maintenance Who Developed Postpartum Torsades de Pointes: Importance of Perinatal Changes in Drug Metabolism.

Spiegel, Ariana / Spiegel, David R / Byrd, Virginia / Hopkins, Katharine

2021 Volume 41, Issue 4, Page(s) 484–487

MeSH term(s)	Adult ; Female ; Humans ; Methadone/therapeutic use ; Opiate Substitution Treatment ; Opioid-Related Disorders/drug therapy ; Pregnancy ; Puerperal Disorders/diagnosis ; Puerperal Disorders/etiology ; Torsades de Pointes/diagnosis ; Torsades de Pointes/etiology
Chemical Substances	Methadone (UC6VBE7V1Z)
Language	English
Publishing date	2021-06-21
Publishing country	United States
Document type	Case Reports ; Letter
ZDB-ID	604631-9
ISSN	1533-712X ; 0271-0749
ISSN (online)	1533-712X
ISSN	0271-0749
DOI	10.1097/JCP.0000000000001426
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Article ; Online: Wernicke's Encephalopathy Due to Hyperemesis Gravidarum Masquerading as Major Depressive Disorder: A Reminder to Assess for At-Risk Thiamine Deficiency States.

Spiegel, Ariana / Spiegel, David R / McLean, Abbey / Monter, Elizabeth / Cronin, Anna / Kamano, Elisabeth

The primary care companion for CNS disorders

2022 Volume 24, Issue 3

MeSH term(s)	Depressive Disorder, Major/complications ; Depressive Disorder, Major/diagnosis ; Female ; Humans ; Hyperemesis Gravidarum/complications ; Hyperemesis Gravidarum/diagnosis ; Pregnancy ; Thiamine Deficiency/complications ; Thiamine Deficiency/diagnosis ; Wernicke Encephalopathy/diagnosis ; Wernicke Encephalopathy/etiology
Language	English
Publishing date	2022-05-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	2675414-9
ISSN	2155-7780 ; 2155-7780
ISSN (online)	2155-7780
ISSN	2155-7780
DOI	10.4088/PCC.21cr03032
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Self-reported silica exposures and workplace protections among engineered stone fabrication workers in California.

Spiegel, Ariana / Cummings, Kristin J / Flattery, Jennifer / Harrison, Robert / Heinzerling, Amy

American journal of industrial medicine

2022 Volume 65, Issue 12, Page(s) 1022–1024

MeSH term(s)	Humans ; Workplace ; Self Report ; Air Pollutants, Occupational/analysis ; California ; Silicon Dioxide/analysis ; Occupational Exposure/adverse effects ; Occupational Exposure/prevention & control ; Occupational Exposure/analysis
Chemical Substances	Air Pollutants, Occupational ; Silicon Dioxide (7631-86-9)
Language	English
Publishing date	2022-10-10
Publishing country	United States
Document type	Letter ; Research Support, U.S. Gov't, P.H.S.
ZDB-ID	604538-8
ISSN	1097-0274 ; 0271-3586
ISSN (online)	1097-0274
ISSN	0271-3586
DOI	10.1002/ajim.23432
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A Case of Wernicke-Korsakoff Syndrome Initially Diagnosed as Autoimmune Limbic Encephalitis: Differential Diagnosis of Delirium and Short-Term Memory Deficits.

Spiegel, David R / O'Connell, Katie / Stocker, Gary / Slater, Jarrett / Spiegel, Ariana

The primary care companion for CNS disorders

2020 Volume 22, Issue 5

MeSH term(s)	Autoimmune Diseases ; Delirium/diagnosis ; Diagnosis, Differential ; Humans ; Korsakoff Syndrome/diagnosis ; Limbic Encephalitis ; Memory, Short-Term
Language	English
Publishing date	2020-10-08
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2675414-9
ISSN	2155-7780 ; 2155-7780
ISSN (online)	2155-7780
ISSN	2155-7780
DOI	10.4088/PCC.20l02693
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Article ; Online: A Case of Treatment-Refractory Hyperemesis Gravidarum Responsive to Adjunctive Mirtazapine in a Patient With Anxiety Comorbidity and Severe Weight Loss.

Spiegel, David R / Ramchandani, Juhi / Spiegel, Ariana / Samaras, Anastasia / Johnson, Kelsey / McAuliffe, Ryan / Nason, Katlynn

Journal of clinical psychopharmacology

2020 Volume 40, Issue 5, Page(s) 509–512

MeSH term(s)	Anti-Anxiety Agents/therapeutic use ; Antiemetics/therapeutic use ; Anxiety/diagnosis ; Anxiety/drug therapy ; Anxiety/psychology ; Comorbidity ; Female ; Humans ; Hyperemesis Gravidarum/diagnosis ; Hyperemesis Gravidarum/drug therapy ; Hyperemesis Gravidarum/physiopathology ; Hyperemesis Gravidarum/psychology ; Mirtazapine/therapeutic use ; Pregnancy ; Treatment Outcome ; Weight Loss ; Young Adult
Chemical Substances	Anti-Anxiety Agents ; Antiemetics ; Mirtazapine (A051Q2099Q)
Language	English
Publishing date	2020-07-07
Publishing country	United States
Document type	Case Reports ; Letter
ZDB-ID	604631-9
ISSN	1533-712X ; 0271-0749
ISSN (online)	1533-712X
ISSN	0271-0749
DOI	10.1097/JCP.0000000000001268
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Article ; Online: Homelessness in pregnancy: perinatal outcomes.

St Martin, Brad S / Spiegel, Ariana M / Sie, Lillian / Leonard, Stephanie A / Seidman, Dominika / Girsen, Anna I / Shaw, Gary M / El-Sayed, Yasser Y

Journal of perinatology : official journal of the California Perinatal Association

2021 Volume 41, Issue 12, Page(s) 2742–2748

Abstract: Objective: Investigate the association between maternal homelessness at the time of delivery and perinatal outcomes, with a focus on neonatal health outcomes.: Study design: Population-based cohort using California's statewide database included 1,520, ...

Abstract	Objective: Investigate the association between maternal homelessness at the time of delivery and perinatal outcomes, with a focus on neonatal health outcomes. Study design: Population-based cohort using California's statewide database included 1,520,253 women with linked birth and maternal discharge data, 2008-2012. Multivariable analysis assessed homelessness at time of delivery on perinatal outcomes, preterm delivery, and neonatal intensive care unit admission. Result: A total of 672 women (0.05%) were homeless at the time of delivery. Homelessness was associated with premature delivery at multiple gestational age cutoffs (34w0d-36w6d; 32w0d-33w6d; 28w0d-31w6d; <28w0d) (range of aORs:1.62-2.19), and neonatal intensive care unit admission (aOR = 1.66, 95% CI:1.31-2.09). Among term infants, homelessness remained associated with increased odds of neonatal intensive care unit admission (aOR = 1.84, 95% CI:1.34-2.53), low birthweight (aOR = 1.99, 95% CI:1.36-2.90), neonatal abstinence syndrome (aOR = 2.13, 95% CI:1.35-2.53), hypoxic-ischemic encephalopathy (aOR = 14.38, 95% CI:3.90-53.01), and necrotizing enterocolitis (aOR = 14.94, 95% CI:2.68-83.20). Conclusion: Homelessness in pregnancy was associated with adverse perinatal outcomes including increased odds of preterm delivery across all gestational ages, and increased risk of neonatal intensive care unit admission and low birth weight independent of preterm delivery.
MeSH term(s)	Female ; Gestational Age ; Homeless Persons ; Humans ; Infant ; Infant, Low Birth Weight ; Infant, Newborn ; Neonatal Abstinence Syndrome ; Pregnancy ; Pregnancy Outcome/epidemiology ; Premature Birth/epidemiology ; Retrospective Studies
Language	English
Publishing date	2021-08-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	645021-0
ISSN	1476-5543 ; 0743-8346
ISSN (online)	1476-5543
ISSN	0743-8346
DOI	10.1038/s41372-021-01187-3
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Article ; Online: A Genome-Wide Analysis of Clinical Chorioamnionitis among Preterm Infants.

Spiegel, Ariana M / Li, Jingjing / Oehlert, John W / Mayo, Jonathan A / Quaintance, Cecele C / Girsen, Anna I / Druzin, Maurice L / El-Sayed, Yasser Y / Shaw, Gary M / Stevenson, David K / Gibbs, Ronald S

American journal of perinatology

2019 Volume 36, Issue 14, Page(s) 1453–1458

Abstract: Objective: To identify single nucleotide polymorphisms (SNPs) associated with clinical chorioamnionitis among preterm infants.: Study design: We reanalyzed a genome-wide association study (GWAS) from preterm newborns at less than 30 weeks' gestation. ...

Abstract	Objective: To identify single nucleotide polymorphisms (SNPs) associated with clinical chorioamnionitis among preterm infants. Study design: We reanalyzed a genome-wide association study (GWAS) from preterm newborns at less than 30 weeks' gestation. Cases and control definitions were determined using administrative records. There were 213 clinical chorioamnionitis cases and 707 clinically uninfected controls. We compared demographic and clinical outcomes of cases and controls. We performed a GWAS and compared the distribution of SNPs from the background genes and from the immunome genes. We used a Wilcoxon's rank-sum test to compare the SNPs normalized odds ratio and used odds ratios and Results: Infants affected by clinical chorioamnionitis were more likely to have periventricular leukomalacia, high-grade retinopathy, and high-grade intraventricular hemorrhage (IVH). Although a GWAS did not identify SNPs associated with clinical chorioamnionitis at the genome-wide significance level, a direct test on the exonic variants in the human immunome revealed their significant increase of risk in clinical chorioamnionitis. Conclusion: Among very preterm infants, clinical chorioamnionitis was associated with periventricular leukomalacia, high-grade retinopathy, and IVH. Our analysis of variants in the human immunome indicates an association with clinical chorioamnionitis in very preterm pregnancies.
MeSH term(s)	Adult ; Case-Control Studies ; Cerebral Intraventricular Hemorrhage/genetics ; Cerebral Intraventricular Hemorrhage/immunology ; Chorioamnionitis/genetics ; Chorioamnionitis/immunology ; Female ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Humans ; Immunity/genetics ; Infant, Newborn ; Infant, Premature ; Infant, Premature, Diseases ; Leukomalacia, Periventricular/genetics ; Leukomalacia, Periventricular/immunology ; Male ; Polymorphism, Single Nucleotide ; Pregnancy ; Retinopathy of Prematurity/genetics ; Retinopathy of Prematurity/immunology
Language	English
Publishing date	2019-01-23
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	605671-4
ISSN	1098-8785 ; 0735-1631
ISSN (online)	1098-8785
ISSN	0735-1631
DOI	10.1055/s-0038-1677503
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The social psychology of perception experiments: hills, backpacks, glucose, and the problem of generalizability.

Durgin, Frank H / Klein, Brennan / Spiegel, Ariana / Strawser, Cassandra J / Williams, Morgan

Journal of experimental psychology. Human perception and performance

2012 Volume 38, Issue 6, Page(s) 1582–1595

Abstract: Experiments take place in a physical environment but also a social environment. Generalizability from experimental manipulations to more typical contexts may be limited by violations of ecological validity with respect to either the physical or the ... ...

Abstract	Experiments take place in a physical environment but also a social environment. Generalizability from experimental manipulations to more typical contexts may be limited by violations of ecological validity with respect to either the physical or the social environment. A replication and extension of a recent study (a blood glucose manipulation) was conducted to investigate the effects of experimental demand (a social artifact) on participant behaviors judging the geographical slant of a large-scale outdoor hill. Three different assessments of experimental demand indicate that even when the physical environment is naturalistic, and the goal of the main experimental manipulation was primarily concealed, artificial aspects of the social environment (such as an explicit requirement to wear a heavy backpack while estimating the slant of a hill) may still be primarily responsible for altered judgments of hill orientation.
MeSH term(s)	Attitude ; Awareness ; Blood Glucose ; Cooperative Behavior ; Fatigue ; Female ; Humans ; Judgment ; Male ; Reproducibility of Results ; Research Design ; Social Environment ; Space Perception
Chemical Substances	Blood Glucose
Language	English
Publishing date	2012-03-19
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	189734-2
ISSN	1939-1277 ; 0096-1523
ISSN (online)	1939-1277
ISSN	0096-1523
DOI	10.1037/a0027805
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Article ; Online: On the anisotropy of perceived ground extents and the interpretation of walked distance as a measure of perception.

Li, Zhi / Sun, Emily / Strawser, Cassandra J / Spiegel, Ariana / Klein, Brennan / Durgin, Frank H

Journal of experimental psychology. Human perception and performance

2012 Volume 39, Issue 2, Page(s) 477–493

Abstract: Two experiments are reported concerning the perception of ground extent to discover whether prior reports of anisotropy between frontal extents and extents in depth were consistent across different measures (visual matching and pantomime walking) and ... ...

Abstract	Two experiments are reported concerning the perception of ground extent to discover whether prior reports of anisotropy between frontal extents and extents in depth were consistent across different measures (visual matching and pantomime walking) and test environments (outdoor environments and virtual environments). In Experiment 1 it was found that depth extents of up to 7 m are indeed perceptually compressed relative to frontal extents in an outdoor environment, and that perceptual matching provided more precise estimates than did pantomime walking. In Experiment 2, similar anisotropies were found using similar tasks in a similar (but virtual) environment. In both experiments pantomime walking measures seemed to additionally compress the range of responses. Experiment 3 supported the hypothesis that range compression in walking measures of perceived distance might be due to proactive interference (memory contamination). It is concluded that walking measures are calibrated for perceived egocentric distance, but that pantomime walking measures may suffer range compression. Depth extents along the ground are perceptually compressed relative to frontal ground extents in a manner consistent with the angular scale expansion hypothesis.
MeSH term(s)	Anisotropy ; Auditory Perception ; Depth Perception ; Discrimination Learning ; Distance Perception ; Female ; Humans ; Imitative Behavior ; Kinesthesis ; Male ; Orientation ; Proprioception ; Sensory Deprivation ; Students/psychology ; User-Computer Interface ; Visual Perception ; Walking/psychology
Language	English
Publishing date	2012-08-13
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	189734-2
ISSN	1939-1277 ; 0096-1523
ISSN (online)	1939-1277
ISSN	0096-1523
DOI	10.1037/a0029405
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Article: A Genome-Wide Analysis of Clinical Chorioamnionitis among Preterm Infants

Spiegel, Ariana M. / Li, Jingjing / Oehlert, John W. / Mayo, Jonathan A. / Quaintance, Cecele C. / Girsen, Anna I. / Druzin, Maurice L. / El-Sayed, Yasser Y. / Shaw, Gary M. / Stevenson, David K. / Gibbs, Ronald S.

American Journal of Perinatology

2019 Volume 36, Issue 14, Page(s) 1453–1458

Abstract: Objective: To identify single nucleotide polymorphisms (SNPs) associated with clinical chorioamnionitis among preterm infants.: Study Design: We reanalyzed a genome-wide association study (GWAS) from preterm newborns at less than 30 weeks' gestation. ...

Abstract	Objective: To identify single nucleotide polymorphisms (SNPs) associated with clinical chorioamnionitis among preterm infants. Study Design: We reanalyzed a genome-wide association study (GWAS) from preterm newborns at less than 30 weeks' gestation. Cases and control definitions were determined using administrative records. There were 213 clinical chorioamnionitis cases and 707 clinically uninfected controls. We compared demographic and clinical outcomes of cases and controls. We performed a GWAS and compared the distribution of SNPs from the background genes and from the immunome genes. We used a Wilcoxon's rank-sum test to compare the SNPs normalized odds ratio and used odds ratios and p -values to determine candidate genes. Results: Infants affected by clinical chorioamnionitis were more likely to have periventricular leukomalacia, high-grade retinopathy, and high-grade intraventricular hemorrhage (IVH). Although a GWAS did not identify SNPs associated with clinical chorioamnionitis at the genome-wide significance level, a direct test on the exonic variants in the human immunome revealed their significant increase of risk in clinical chorioamnionitis. Conclusion: Among very preterm infants, clinical chorioamnionitis was associated with periventricular leukomalacia, high-grade retinopathy, and IVH. Our analysis of variants in the human immunome indicates an association with clinical chorioamnionitis in very preterm pregnancies.
Keywords	candidate gene ; analysis ; clinical chorioamnionitis ; genome-wide association study ; preterm birth
Language	English
Publishing date	2019-01-23
Publisher	Thieme Medical Publishers
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	605671-4
ISSN	1098-8785 ; 0735-1631
ISSN (online)	1098-8785
ISSN	0735-1631
DOI	10.1055/s-0038-1677503
Database	Thieme publisher's database

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