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  1. Article ; Conference proceedings: Diagnostischer Nutzen eines modifizierten fokussierten Herzultraschalls bei tachykarden Herzrhythmusstörungen an der Notaufnahme – eine Pilotstudie

    Simon, Alexander / Spiel, Alexander / Tumnitz, Elvis

    Ultraschall in der Medizin - European Journal of Ultrasound

    2022  Volume 43, Issue S 01

    Event/congress Interdisziplinärer Kongress | Ultraschall 2022, Zürich, 2022-06-29
    Language German
    Publishing date 2022-06-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 801064-x
    ISSN 1438-8782 ; 0172-4614 ; 1439-0914 ; 1431-4894
    ISSN (online) 1438-8782
    ISSN 0172-4614 ; 1439-0914 ; 1431-4894
    DOI 10.1055/s-0042-1749525
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1572: Show issues Location:
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  2. Article: A Gastrocolic Fistula Presenting as Chronic Diarrhea.

    Spiel, Andrew / Shada, Amber / Lomeli, Luis

    ACG case reports journal

    2020  Volume 7, Issue 2, Page(s) e00326

    Language English
    Publishing date 2020-02-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.0000000000000326
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Carotid Artery Ultrasound in the (peri-) Arrest Setting-A Prospective Pilot Study.

    Koch, Moritz / Mueller, Matthias / Warenits, Alexandra-Maria / Holzer, Michael / Spiel, Alexander / Schnaubelt, Sebastian

    Journal of clinical medicine

    2022  Volume 11, Issue 2

    Abstract: Point-of-care ultrasounds (US) are used during cardiopulmonary resuscitation (CPR) and after return of spontaneous circulation (ROSC). Carotid ultrasounds are a potential non-invasive monitoring tool for chest compressions, but their general value and ... ...

    Abstract Point-of-care ultrasounds (US) are used during cardiopulmonary resuscitation (CPR) and after return of spontaneous circulation (ROSC). Carotid ultrasounds are a potential non-invasive monitoring tool for chest compressions, but their general value and feasibility during CPR are not fully determined. In this prospective observational study, we performed carotid US during conventional- and extracorporeal CPR and after ROSC with at least one transverse and coronal image, corresponding loops with and without color doppler, and pulsed-wave doppler loops. The feasibility of carotid US during (peri-)arrest and type and frequency of diagnostic findings were examined. We recruited 16 patients and recorded utilizable US images in 14 cases (88%; complete imaging protocols in 11 patients [69%]). In three of all patients (19%) and in 60% (3/5) of cases during CPR plus a full imaging protocol, we observed: (i) in one patient a collapse of the common carotid artery linked to hypovolemia, and (ii) in two patients a biphasic flow during CPR linked to prolonged low-flow time prior to admission and adverse outcome. Carotid artery morphology and carotid blood flow characteristics may serve as therapeutic target and prognostic parameters. However, future studies with larger sample sizes are needed.
    Language English
    Publishing date 2022-01-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11020469
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  4. Article: Management von Patienten mit Vorhofflimmern - wie und wo?

    Spiel, A. / Domanovits, H.

    Jatros : Kardiologie & Gefäßmedizin : das Fachmedium für Herz-Kreislauf-Erkrankungen

    2014  Volume 19, Issue 1, Page(s) 21

    Language German
    Document type Article
    ZDB-ID 2229370-X
    ISSN 1997-8235 ; 0943-3341
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6778: Show issues Location:
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  5. Article: Computed Tomography to Exclude Cardiac Thrombus in Atrial Fibrillation-An 11-Year Experience from an Academic Emergency Department.

    Gupta, Sophie / Lutnik, Martin / Cacioppo, Filippo / Lindmayr, Teresa / Schuetz, Nikola / Tumnitz, Elvis / Friedl, Lena / Boegl, Magdalena / Schnaubelt, Sebastian / Domanovits, Hans / Spiel, Alexander / Toth, Daniel / Varga, Raoul / Raudner, Marcus / Herkner, Harald / Schwameis, Michael / Niederdoeckl, Jan

    Diagnostics (Basel, Switzerland)

    2024  Volume 14, Issue 7

    Abstract: Background: Computed tomography (CT) could be a suitable method for acute exclusion of left atrial appendage thrombus (LAAT) prior to cardioversion of atrial fibrillation (AF) and atrial flutter (AFL) at the emergency department. Our aim was to present ... ...

    Abstract Background: Computed tomography (CT) could be a suitable method for acute exclusion of left atrial appendage thrombus (LAAT) prior to cardioversion of atrial fibrillation (AF) and atrial flutter (AFL) at the emergency department. Our aim was to present our experiences with this modality in recent years.
    Methods: This registry-based observational study was performed at the Department of Emergency Medicine at the Medical University of Vienna, Austria. We studied all consecutive patients with AF and AFL who underwent CT between January 2012 and January 2023 to rule out LAAT before cardioversion to sinus rhythm was attempted. Follow-ups were conducted by telephone and electronic medical records. The main variables of interest were the rate of LAAT and ischemic stroke at follow-up.
    Results: A total of 234 patients (143 [61%] men; median age 68 years [IQR 57-76], median CHA
    Conclusion: LAAT was rare in patients admitted to the ED with AF and AFL who underwent cardiac CT prior to attempted cardioversion. At follow-up, no patient had suffered an ischemic stroke. Prospective studies need to show whether this strategy is suitable for the acute treatment of symptomatic AF in the emergency setting.
    Language English
    Publishing date 2024-03-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics14070699
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  6. Article ; Conference proceedings: Clinical usefulness of the novel DOAC Dipstick near patient test strip in emergency settings using semi-automatic DOASENSE Reader

    Buchtele, N / Schwameis, M / Merrelaar, A / Schoergenhofer, C / Herkner, H / Jilma, B / Harenberg, J / Ruzicka, G / Spiel, A

    Hämostaseologie

    2021  Volume 41, Issue S 01

    Event/congress 65th Annual Meeting of the Society of Thrombosis and Haemostasis Research, simply online, 2021-02-22
    Language German
    Publishing date 2021-06-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 801512-0
    ISSN 2567-5761 ; 0720-9355
    ISSN (online) 2567-5761
    ISSN 0720-9355
    DOI 10.1055/s-0041-1728169
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  7. Article ; Online: Pulmonary Findings in Hospitalized COVID-19 Patients Assessed by Lung Ultrasonography (LUS) - A Prospective Registry Study.

    Barner, Anna / Burian, Egon / Simon, Alexander / Castillo, Katty / Waschulzik, Birgit / Braren, Rickmer / Heemann, Uwe / Osterwalder, Joseph / Spiel, Alexander / Heim, Markus / Stock, Konrad Friedrich

    Ultraschall in der Medizin (Stuttgart, Germany : 1980)

    2023  Volume 44, Issue 5, Page(s) e248–e256

    Abstract: Purpose: This prospective two-centre study investigated localisation-dependent lesion patterns in COVID-19 with standard lung ultrasonography (LUS) and their relationship with thoracic computed tomography (CT) and clinical parameters.: Materials and ... ...

    Title translation Lungenbefunde bei hospitalisierten COVID-19-Patienten erfasst mittels Lungensonografie (LUS) – Eine prospektive Registerstudie.
    Abstract Purpose: This prospective two-centre study investigated localisation-dependent lesion patterns in COVID-19 with standard lung ultrasonography (LUS) and their relationship with thoracic computed tomography (CT) and clinical parameters.
    Materials and methods: Between April 2020 and April 2021, 52 SARS-CoV-2-positive patients in two hospitals were examined by means of LUS for "B-lines", fragmented pleura, consolidation and air bronchogram in 12 lung regions and for pleural effusions. A newly developed LUS score based on the number of features present was correlated with clinical parameters (respiration, laboratory parameters) and the CT and analysed with respect to the 30- and 60-day outcome. All patients were offered an outpatient LUS follow-up.
    Results: The LUS and CT showed a bilateral, partially posteriorly accentuated lesion distribution pattern. 294/323 (91%) of CT-detected lesions were pleural. The LUS score showed an association with respiratory status and C-reactive protein; the correlation with the CT score was weak (Spearman's rho = 0.339, p < 0.001). High LUS scores on admission were also observed in patients who were discharged within 30 days. LUS during follow-up showed predominantly declining LUS scores.
    Conclusion: The LUS score reflected the clinical condition of the patients. No conclusion could be made on the prognostic value of the LUS, because of the low event rate. The LUS and CT score showed no sufficient correlation. This is probably due to different physical principles, which is why LUS could be of complementary value.
    Language English
    Publishing date 2023-01-16
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 801064-x
    ISSN 1438-8782 ; 1439-0914 ; 1431-4894 ; 0172-4614
    ISSN (online) 1438-8782
    ISSN 1439-0914 ; 1431-4894 ; 0172-4614
    DOI 10.1055/a-2013-8045
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Synchronous obstructive ureterolithiasis and acute appendicitis.

    Spiel, Ar / Cowden, W

    Journal of surgical case reports

    2012  Volume 2012, Issue 9, Page(s) 16

    Abstract: The differential diagnosis of right lower quadrant abdominal pain includes both ureterolithiasis and acute appendicitis. Surgical treatment can be undergone without confirmatory imaging studies after a clinical diagnosis is made. For this reason, an ... ...

    Abstract The differential diagnosis of right lower quadrant abdominal pain includes both ureterolithiasis and acute appendicitis. Surgical treatment can be undergone without confirmatory imaging studies after a clinical diagnosis is made. For this reason, an occult, second abdominal process may be present. A 47-year-old male presented with a three-day history of acute right lower quadrant abdominal pain. A contrast CT revealed both a 6 mm calculus obstructing the right ureter and acute appendicitis. The patient underwent appendectomy and ureteroscopy with stent placement at the same time. Simultaneous appendicitis and ureterolithiasis may present with similar clinical findings. Due to the potential risks associated with missing either diagnosis, imaging studies may be an appropriate as a step in the management of the patient with right lower quadrant pain.
    Language English
    Publishing date 2012-09-01
    Publishing country England
    Document type Journal Article
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/2012.9.16
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  9. Article: Role of von Willebrand factor in vascular disease.

    Paulinska, P / Spiel, A / Jilma, B

    Hamostaseologie

    2009  Volume 29, Issue 1, Page(s) 32–38

    Abstract: Plasma levels of von Willebrand factor (VWF) are increased in patients with cardiovascular risk factors. Various studies aimed to elucidate the relation of VWF with thromboembolic cardiovascular events, ischaemic stroke as well as with peripheral ... ...

    Abstract Plasma levels of von Willebrand factor (VWF) are increased in patients with cardiovascular risk factors. Various studies aimed to elucidate the relation of VWF with thromboembolic cardiovascular events, ischaemic stroke as well as with peripheral arterial occlusive disease. In the general population, there is only a weak association between VWF levels and future cardiovascular events or stroke. In contrast, VWF levels are predictive in patients with documented vascular disease. Those patients with increased VWF suffer a higher incidence of major adverse cardiac events including death. The extent of the VWF release and its levels independently predict clinical outcome in patients with acute coronary syndromes. Elevated VWF levels have also been observed in patients with atrial fibrillation compared to controls and predict outcome. This may at least in part be attributable to the association of VWF with underlying cardiovascular risk factors. Hence, VWF correlates with Framingham and CHADS stroke risk stratification score and can be used as a marker in patients with AF. However, VWF is not only a predictor; it also plays a crucial role in thrombogenesis. This fact has made VWF a promising target for research into new antiplatelet therapies that specifically inhibit VWF. This review focuses on the role of VWF in ACS, ischaemic stroke and peripheral arterial disease and the relevance of therapeutic interventions targeting VWF for ACS patients.
    MeSH term(s) Arterial Occlusive Diseases/blood ; Binding Sites ; Collagen/metabolism ; Coronary Disease/blood ; Coronary Disease/physiopathology ; Factor VIII/metabolism ; Heparin/metabolism ; Humans ; Platelet Membrane Glycoproteins/metabolism ; Reference Values ; Stroke/blood ; Thrombosis/blood ; Thrombosis/physiopathology ; Vascular Diseases/blood ; von Willebrand Factor/metabolism ; von Willebrand Factor/physiology
    Chemical Substances Platelet Membrane Glycoproteins ; von Willebrand Factor ; Factor VIII (9001-27-8) ; Heparin (9005-49-6) ; Collagen (9007-34-5)
    Language English
    Publishing date 2009-01
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 801512-0
    ISSN 0720-9355
    ISSN 0720-9355
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Conference proceedings: Bettseitige Detektion der Wasserscheide mittels CEUS bei Patienten mit veno-arterieller ECMO – Eine prospektive Machbarkeitsstudie

    Buchtele, N / Staudinger, T / Schwameis, M / Schörgenhofer, C / Merrelaar, A / Weiser, C / Hermann, A / Schmid, M / Spiel, A

    Ultraschall in der Medizin - European Journal of Ultrasound

    2019  Volume 40, Issue S 01

    Event/congress Interdisziplinärer Kongress | Ultraschall 2019 - 43. Dreiländertreffen DEGUM | ÖGUM | SGUM, Leipzig, 2019-10-16
    Language German
    Publishing date 2019-08-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 801064-x
    ISSN 1438-8782 ; 0172-4614 ; 1439-0914 ; 1431-4894
    ISSN (online) 1438-8782
    ISSN 0172-4614 ; 1439-0914 ; 1431-4894
    DOI 10.1055/s-0039-1695876
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