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  1. Article ; Online: Clinical findings, orbital imaging, and intraoperative findings in patients with isolated inferior rectus muscle paresis or underaction.

    Spindle, Jordan / Shinder, Roman

    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus

    2013  Volume 17, Issue 1, Page(s) 114

    MeSH term(s) Female ; Humans ; Magnetic Resonance Imaging ; Male ; Oculomotor Muscles/pathology ; Ophthalmoplegia/diagnosis ; Strabismus/diagnosis ; Tomography, X-Ray Computed
    Language English
    Publishing date 2013-02
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 1412476-2
    ISSN 1528-3933 ; 1091-8531
    ISSN (online) 1528-3933
    ISSN 1091-8531
    DOI 10.1016/j.jaapos.2012.09.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5188: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Atypical idiopathic orbital inflammation in a young girl.

    Spindle, Jordan / Narang, Sherry / Purewal, Baljeet / Shinder, Roman

    Ophthalmic plastic and reconstructive surgery

    2013  Volume 29, Issue 3, Page(s) e86–8

    Abstract: A 7-year-old girl presented with chronic right periocular pain worst in abduction, edema, and proptosis with radiographic evidence of right medial rectus myositis. After a negative workup, she was diagnosed and treated for idiopathic orbital inflammation ...

    Abstract A 7-year-old girl presented with chronic right periocular pain worst in abduction, edema, and proptosis with radiographic evidence of right medial rectus myositis. After a negative workup, she was diagnosed and treated for idiopathic orbital inflammation (IOI) with a brisk response to oral steroids. She returned 8 months later with left periocular pain worst in abduction, proptosis, and radiographic evidence of left lateral rectus myositis. She was treated for recurrent and alternating IOI with intravenous (IV) glucocorticoids with resolution. One year later, she recurred with similar left orbital signs and symptoms and was found to have a left inferior oblique myositis on MRI. She was treated with oral steroids and methotrexate with clinical resolution. Ten months later, she presented with left periocular pain worst on adduction and was found to have left medial rectus myositis on MRI. She was treated with IV steroids, IV immunoglobulin, and rituximab with resolution of all symptoms. She is currently maintained on methotrexate and oral glucocorticoids. The atypical pediatric case of IOI over a 4-year period is described in this study.
    MeSH term(s) Antibodies, Monoclonal, Murine-Derived/therapeutic use ; Child ; Drug Therapy, Combination ; Eye Pain/diagnosis ; Eye Pain/drug therapy ; Eye Pain/etiology ; Female ; Glucocorticoids/therapeutic use ; Humans ; Immunoglobulins, Intravenous/therapeutic use ; Immunologic Factors/therapeutic use ; Magnetic Resonance Imaging ; Oculomotor Muscles/pathology ; Orbital Myositis/complications ; Orbital Myositis/diagnosis ; Orbital Myositis/drug therapy ; Rituximab ; Tomography, X-Ray Computed
    Chemical Substances Antibodies, Monoclonal, Murine-Derived ; Glucocorticoids ; Immunoglobulins, Intravenous ; Immunologic Factors ; Rituximab (4F4X42SYQ6)
    Language English
    Publishing date 2013-05
    Publishing country United States
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 632830-1
    ISSN 1537-2677 ; 0740-9303
    ISSN (online) 1537-2677
    ISSN 0740-9303
    DOI 10.1097/IOP.0b013e318275b649
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2159: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  3. Article ; Online: Adult rhabdomyosarcoma of the maxillary sinus with orbital extension.

    Parikh, Deep / Spindle, Jordan / Linden, Craig / Bardarov, Svetoslav / Shinder, Roman

    Orbit (Amsterdam, Netherlands)

    2014  Volume 33, Issue 4, Page(s) 302–304

    Abstract: A 40-year-old male presented with 2 weeks of left facial pain, nasal congestion, dysphonia, and epistaxis along with left-sided epiphora. CT showed a large infiltrative mass centered in the left maxillary sinus with extension into the left orbit, ... ...

    Abstract A 40-year-old male presented with 2 weeks of left facial pain, nasal congestion, dysphonia, and epistaxis along with left-sided epiphora. CT showed a large infiltrative mass centered in the left maxillary sinus with extension into the left orbit, bilateral paranasal sinuses, nasal cavity, and bilateral enlarged cervical lymph nodes. Biopsy results confirmed adult alveolar rhabdomyosarcoma (RMS). Systemic workup confirmed bilateral cervical lymph node metastasis. Currently the patient is undergoing chemotherapy. We describe a rare case of adult paranasal sinus RMS with orbital invasion.
    MeSH term(s) Adult ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Humans ; Lymphatic Metastasis ; Male ; Maxillary Sinus Neoplasms/diagnostic imaging ; Maxillary Sinus Neoplasms/drug therapy ; Maxillary Sinus Neoplasms/pathology ; Orbital Neoplasms/diagnostic imaging ; Orbital Neoplasms/drug therapy ; Orbital Neoplasms/secondary ; Paranasal Sinus Neoplasms/diagnostic imaging ; Paranasal Sinus Neoplasms/drug therapy ; Paranasal Sinus Neoplasms/secondary ; Rhabdomyosarcoma, Alveolar/diagnostic imaging ; Rhabdomyosarcoma, Alveolar/drug therapy ; Rhabdomyosarcoma, Alveolar/secondary ; Tomography, X-Ray Computed
    Language English
    Publishing date 2014-08
    Publishing country England
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603157-2
    ISSN 1744-5108 ; 0167-6830
    ISSN (online) 1744-5108
    ISSN 0167-6830
    DOI 10.3109/01676830.2014.902480
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    Zs.A 1735: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Central retinal artery occlusion in a patient with tetralogy of Fallot.

    Tsai, Frank F / Spindle, Jordan D / Lazzaro, E C / Olumba, Kenneth C

    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus

    2013  Volume 17, Issue 6, Page(s) 621–622

    Abstract: A 17-year-old Caribbean male presented with painless acute vision loss in the left eye. The patient was found to have a central retinal artery occlusion and an underlying uncorrected tetralogy of Fallot. To our knowledge, this is the first such reported ... ...

    Abstract A 17-year-old Caribbean male presented with painless acute vision loss in the left eye. The patient was found to have a central retinal artery occlusion and an underlying uncorrected tetralogy of Fallot. To our knowledge, this is the first such reported case. One week after presentation visual acuity in the left eye spontaneously improved to 20/200.
    MeSH term(s) Adolescent ; Humans ; Male ; Retinal Artery Occlusion/etiology ; Tetralogy of Fallot/complications ; Vision, Low/etiology
    Language English
    Publishing date 2013-12
    Publishing country United States
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1412476-2
    ISSN 1528-3933 ; 1091-8531
    ISSN (online) 1528-3933
    ISSN 1091-8531
    DOI 10.1016/j.jaapos.2013.06.018
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    Zs.A 5188: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Pediatric Idiopathic Orbital Inflammation: Clinical Features of 30 Cases.

    Spindle, Jordan / Tang, Sunny X / Davies, Brett / Wladis, Edward J / Piozzi, Elena / Pellegrini, Marco / Lally, Sara E / Shields, Carol / Shinder, Roman

    Ophthalmic plastic and reconstructive surgery

    2016  Volume 32, Issue 4, Page(s) 270–274

    Abstract: Purpose: Pediatric idiopathic orbital inflammation (IOI) is a rare entity with little known about the clinical presentation and natural history. The authors report the demographics, clinical presentations, radiographic and histopathologic ... ...

    Abstract Purpose: Pediatric idiopathic orbital inflammation (IOI) is a rare entity with little known about the clinical presentation and natural history. The authors report the demographics, clinical presentations, radiographic and histopathologic characteristics, and treatment outcome of 30 children with IOI.
    Methods: Retrospective chart review of 30 patients 18 years and younger diagnosed with IOI and statistical analysis using analysis of variance and Fisher's exact test. This study was reviewed and approved by the Institutional Review Board of SUNY Downstate Medical Center.
    Results: There were 9 males (30%) and 21 females (70%) with pediatric IOI who presented at a median age of 11 years (range 2-18 years). Primary IOI was found in 19 patients (63%) and recurrent IOI in 11 patients (37%). Overall, 26 patients (87%) had unilateral IOI while 4 patients (13%) had bilateral disease at presentation. There were 12 patients (40%) with systemic constitutional signs. The most common ophthalmic findings included periorbital edema (n = 20, 67%) and blepharoptosis (n = 17, 57%). All patients had orbital radiography with common findings of dacryoadenitis (n = 12, 40%), orbital mass (n = 12, 40%), or myositis (n=10, 33%). The presence of a radiographic orbital mass was significantly related to the clinical presence of blepharoptosis (p = 0.03). The most common treatment was oral glucocorticoids in 24 patients (80%). Over mean follow up of 19 months (range 6-64 months), females were more likely to display recurrent disease (p = 0.01).
    Conclusions: Idiopathic orbital inflammation is an uncommon but important cause of acute orbital syndrome in children, manifesting as a bilateral condition in 13% and with constitutional symptoms in 40%. Posttreatment recurrence is found in 37% of cases.
    MeSH term(s) Adolescent ; Biopsy ; Child ; Child, Preschool ; Diagnosis, Differential ; Female ; Follow-Up Studies ; Glucocorticoids/administration & dosage ; Humans ; Injections, Intravenous ; Male ; Orbit/diagnostic imaging ; Orbital Pseudotumor/diagnosis ; Orbital Pseudotumor/drug therapy ; Retrospective Studies ; Time Factors ; Tomography, X-Ray Computed ; Treatment Outcome
    Chemical Substances Glucocorticoids
    Language English
    Publishing date 2016-07
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 632830-1
    ISSN 1537-2677 ; 0740-9303
    ISSN (online) 1537-2677
    ISSN 0740-9303
    DOI 10.1097/IOP.0000000000000494
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2159: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Orbital floor fracture with entrapment: Imaging and clinical correlations in 45 cases.

    Silverman, Nora / Spindle, Jordan / Tang, Sunny X / Wu, Andrew / Hong, Bryan K / Shore, John W / Wester, Sara / Levin, Flora / Connor, Michael / Burt, Benjamin / Nakra, Tanuj / Shepler, Todd / Hink, Eric / El-Sawy, Tarek / Shinder, Roman

    Orbit (Amsterdam, Netherlands)

    2017  Volume 36, Issue 5, Page(s) 331–336

    Abstract: Orbital floor fractures (OFF) with entrapment require prompt clinical and radiographic recognition for timely surgical correction. Correct CT radiographic interpretation of entrapped fractures can be subtle and thus missed. We reviewed the clinical, ... ...

    Abstract Orbital floor fractures (OFF) with entrapment require prompt clinical and radiographic recognition for timely surgical correction. Correct CT radiographic interpretation of entrapped fractures can be subtle and thus missed. We reviewed the clinical, radiographic and intraoperative findings of 45 cases of entrapped OFF to correlate pre- and intraoperative findings with radiography. Retrospective review and statistical analysis of 45 patients with OFF using the chi squared and Kruskal-Wallis tests. Main outcome measures included patient demographics, clinical features, radiologic interpretation, intraoperative findings, and treatment outcomes. Twenty-one cases (47%) had radiologic evaluations of orbital CT scans that included commentary on possible entrapment. Intraoperatively, 16 (76%) of these patients had the inferior rectus muscle incarcerated in the fracture, while 5 (24%) patients had incarceration of the orbital fat. Possibility of entrapment was not commented on in the radiology reports of the remaining 24 (53%) cases. Intraoperatively, 13 (54%) of these patients had the inferior rectus muscle incarcerated in the fracture, while 11 (46%) patients had incarceration of the orbital fat. It is vital to assess the possibility of entrapment, especially in young patients, in the setting of OFF as a delay in diagnosis may lead to persistent diplopia, disfigurement, or bradycardia. Most radiology reports did not mention the possibility of entrapment in this cohort. A key concept is that entrapment occurs when any orbital tissue (muscle or fat) is trapped in the fracture site.
    Language English
    Publishing date 2017-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 603157-2
    ISSN 1744-5108 ; 0167-6830
    ISSN (online) 1744-5108
    ISSN 0167-6830
    DOI 10.1080/01676830.2017.1337180
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1735: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Association of dyslipidemia in moderate to severe meibomian gland dysfunction.

    Dao, Adam H / Spindle, Jordan D / Harp, Blake A / Jacob, Arun / Chuang, Alice Z / Yee, Richard W

    American journal of ophthalmology

    2010  Volume 150, Issue 3, Page(s) 371–375.e1

    Abstract: Purpose: To determine whether meibomian gland disease, a major contributor to dry eye syndrome, is associated with dyslipidemia.: Design: Retrospective case-control study.: Methods: setting: Clinical practice. patient or study population: Sixty- ... ...

    Abstract Purpose: To determine whether meibomian gland disease, a major contributor to dry eye syndrome, is associated with dyslipidemia.
    Design: Retrospective case-control study.
    Methods: setting: Clinical practice. patient or study population: Sixty-six patients from January 2008 to July 2009 with moderate to severe meibomian gland disease whose serum lipid levels were obtained. We excluded patients who were already taking lipid-altering substances and patients with rheumatologic disease. We analyzed several parameters in prevalence of dyslipidemia (total cholesterol > 200 mg/dL, low-density lipoprotein [LDL] > 130 mg/dL, high-density lipoprotein [HDL] < 40 mg/dL, and triglycerides >150 mg/dL) in MGD patients and compared these patients to the general population as reported by data from the National Health and Nutrition Examination Survey (NHANES). main outcome measure: The prevalence of dyslipidemia (elevated total cholesterol, elevated LDL, decreased HDL, or elevated triglycerides) in patients with moderate to severe MGD.
    Results: Patients with moderate to severe MGD had a higher incidence of dyslipidemia with respect to elevated total cholesterol (>200 mg/dL), 67.4% to 45.1% (P = .0012) when compared to population controls. There was a smaller number of MGD patients with low HDL (HDL < 40 mg/dL), 6.5%, when compared to controls, 15.7% (P = .045). The incidence of increased LDL was not statistically significant (P = .184). There was a statistically smaller number of MGD patients with high triglycerides (TG > 150 mg/dL), 15.2%, when compared to controls, 33.1% (P = .0049).
    Conclusions: Patients with moderate to severe MGD have a higher incidence of dyslipidemia with respect to elevated total cholesterol than the general population. Surprisingly, the component of total cholesterol that contributed most to this increase in total cholesterol came from elevated serum HDL levels. To our knowledge, elevated HDL has not been associated with any pathologic state. Patients with MGD had a statistically significant lower incidence of hypoalphalipoproteinemia (low HDL) than the general population. Patients with MGD also had a lower incidence of hypertriglyceridemia than the general population.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Case-Control Studies ; Dyslipidemias/blood ; Dyslipidemias/complications ; Eyelid Diseases/blood ; Eyelid Diseases/complications ; Fatty Acids, Omega-3/administration & dosage ; Female ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage ; Incidence ; Lipids/blood ; Male ; Meibomian Glands/pathology ; Middle Aged ; Prevalence ; Retrospective Studies
    Chemical Substances Fatty Acids, Omega-3 ; Hydroxymethylglutaryl-CoA Reductase Inhibitors ; Lipids
    Language English
    Publishing date 2010-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80030-2
    ISSN 1879-1891 ; 0002-9394
    ISSN (online) 1879-1891
    ISSN 0002-9394
    DOI 10.1016/j.ajo.2010.04.016
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    Ul I Zs.39: Show issues Location:
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