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  1. Article ; Online: Parallel Evolution of Asco- and Basidiomycete

    Schäfer, Tim / Haun, Fabian / Gressler, Markus / Spiteller, Peter / Hoffmeister, Dirk

    Journal of natural products

    2024  Volume 87, Issue 3, Page(s) 576–582

    Abstract: Prenyltransferases (PTs) are involved in the biosynthesis of a multitude of pharmaceutically and agriculturally important plant, bacterial, and fungal compounds. Although numerous prenylated compounds have been isolated from Basidiomycota (mushroom- ... ...

    Abstract Prenyltransferases (PTs) are involved in the biosynthesis of a multitude of pharmaceutically and agriculturally important plant, bacterial, and fungal compounds. Although numerous prenylated compounds have been isolated from Basidiomycota (mushroom-forming fungi), knowledge of the PTs catalyzing the transfer reactions in this group of fungi is scarce. Here, we report the biochemical characterization of an
    MeSH term(s) Dimethylallyltranstransferase/genetics ; Dimethylallyltranstransferase/metabolism ; Phylogeny ; Tyrosine ; Basidiomycota/genetics ; Basidiomycota/metabolism ; Prenylation
    Chemical Substances Dimethylallyltranstransferase (EC 2.5.1.1) ; Tyrosine (42HK56048U)
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 304325-3
    ISSN 1520-6025 ; 0163-3864
    ISSN (online) 1520-6025
    ISSN 0163-3864
    DOI 10.1021/acs.jnatprod.3c01120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Withanolides from Discopodium penninervium.

    Bedane, Kibrom Gebreheiwot / Desta, Mekonnen Abebayehu / Spiteller, Peter

    Fitoterapia

    2023  Volume 167, Page(s) 105478

    Abstract: Discopodium penninervium is a medicinal plant endemic to Ethiopia. Its twigs extract led to the isolation of three new withanolides, discopodinolides A - C, and four known analogues. The structures of the compounds were elucidated using NMR, HRMS data ... ...

    Abstract Discopodium penninervium is a medicinal plant endemic to Ethiopia. Its twigs extract led to the isolation of three new withanolides, discopodinolides A - C, and four known analogues. The structures of the compounds were elucidated using NMR, HRMS data analyses, and literature data. The relative configurations were defined by single-crystal X-ray crystallography and NOESY correlations. The antibacterial efficacy of the isolated compounds was evaluated against four commonly dispersed environmental strains of Escherichia coli, Bacillus subtilis, Bacillus pumilus, and Bacillus megaterium. Discopodinolides B and C exhibited moderate antibacterial activities against the pathogenic strains of E. coli, B. subtilis, and B. megaterium.
    MeSH term(s) Withanolides/pharmacology ; Withanolides/chemistry ; Molecular Structure ; Escherichia coli ; Anti-Bacterial Agents ; Plants, Medicinal/chemistry
    Chemical Substances Withanolides ; Anti-Bacterial Agents
    Language English
    Publishing date 2023-03-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 412385-2
    ISSN 1873-6971 ; 0367-326X
    ISSN (online) 1873-6971
    ISSN 0367-326X
    DOI 10.1016/j.fitote.2023.105478
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: 19

    Mysegaes, Felix / Spiteller, Peter / Bernarding, Johannes / Plaumann, Markus

    Chemphyschem : a European journal of chemical physics and physical chemistry

    2023  Volume 24, Issue 18, Page(s) e202300057

    Abstract: In the past few decades, magnetic resonance spectroscopy (MRS) and MR imaging (MRI) have developed into a powerful non-invasive tool for medical diagnostic and therapy. ... ...

    Abstract In the past few decades, magnetic resonance spectroscopy (MRS) and MR imaging (MRI) have developed into a powerful non-invasive tool for medical diagnostic and therapy. Especially
    Language English
    Publishing date 2023-07-24
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2025223-7
    ISSN 1439-7641 ; 1439-4235
    ISSN (online) 1439-7641
    ISSN 1439-4235
    DOI 10.1002/cphc.202300057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: 19

    Mysegaes, Felix / Spiteller, Peter / Bernarding, Johannes / Plaumann, Markus

    Chemphyschem : a European journal of chemical physics and physical chemistry

    2023  Volume 24, Issue 18, Page(s) e202300577

    Abstract: The front cover artwork is provided by Dr. Markus Plaumann's group at the Otto-von-Guericke University Magdeburg. The image shows the ... ...

    Abstract The front cover artwork is provided by Dr. Markus Plaumann's group at the Otto-von-Guericke University Magdeburg. The image shows the investigated
    Language English
    Publishing date 2023-09-15
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2025223-7
    ISSN 1439-7641 ; 1439-4235
    ISSN (online) 1439-7641
    ISSN 1439-4235
    DOI 10.1002/cphc.202300577
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Chemical ecology of fungi.

    Spiteller, Peter

    Natural product reports

    2015  Volume 32, Issue 7, Page(s) 971–993

    Abstract: Fungi are widespread in nature and have conquered nearly every ecological niche. Fungi occur not only in terrestrial but also in freshwater and marine environments. Moreover, fungi are known as a rich source of secondary metabolites. Despite these facts, ...

    Abstract Fungi are widespread in nature and have conquered nearly every ecological niche. Fungi occur not only in terrestrial but also in freshwater and marine environments. Moreover, fungi are known as a rich source of secondary metabolites. Despite these facts, the ecological role of many of these metabolites is still unknown and the chemical ecology of fungi has not been investigated systematically so far. This review intends to present examples of the various chemical interactions of fungi with other fungi, plants, bacteria and animals and to give an overview of the current knowledge of fungal chemical ecology.
    MeSH term(s) Ecology ; Fungi/chemistry ; Fungi/physiology ; Molecular Structure ; Soil Microbiology
    Language English
    Publishing date 2015-07
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2002546-4
    ISSN 1460-4752 ; 0265-0568
    ISSN (online) 1460-4752
    ISSN 0265-0568
    DOI 10.1039/c4np00166d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: E- and Z-Proxamidines, Unprecedented 1,3-Diazacyclooct-1-ene Alkaloids from Fruiting Bodies of Laccaria proxima.

    Schrey, Hedda / Spiteller, Peter

    Chemistry (Weinheim an der Bergstrasse, Germany)

    2019  Volume 25, Issue 34, Page(s) 8035–8042

    Abstract: Fruiting bodies of Laccaria proxima were screened for the presence of new secondary metabolites by means of HPLC-UV and LC-HR-(+)-ESIMS. Thus, two isomeric alkaloids with a highly unusual core structure, E-proxamidine and its Z-isomer, were isolated from ...

    Abstract Fruiting bodies of Laccaria proxima were screened for the presence of new secondary metabolites by means of HPLC-UV and LC-HR-(+)-ESIMS. Thus, two isomeric alkaloids with a highly unusual core structure, E-proxamidine and its Z-isomer, were isolated from Laccaria proxima. The proxamidines consist of an eight-membered heterocyclic ring system with a formamidine unit. The structures were established by 2D NMR spectroscopic methods, HR-(+)-ESIMS, and HR-(+)-ESIMS/MS. The proxamidines are probably biosynthetically derived from tryptophan, dimethylallyl pyrophosphate, and S-adenosylmethionine and the eight-membered ring of the proxamidines is likely to be generated by a rearrangement of the tryptophan sceleton. Metabolic profiling of fruiting bodies of some other Laccaria species revealed that the proxamidines appear in significant amounts only in L. proxima making the compounds suitable as chemotaxonomic markers. E-Proxamidine exhibits herbicidal activity against Lepidium sativum.
    Language English
    Publishing date 2019-05-17
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1478547-X
    ISSN 1521-3765 ; 0947-6539
    ISSN (online) 1521-3765
    ISSN 0947-6539
    DOI 10.1002/chem.201900566
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Two fluorinated thulium complexes as molecular temperature sensors in MR applications.

    Mysegaes, Felix / Voigt, Pauline / Spiteller, Peter / Prediger, Isabell / Bernarding, Johannes / Plaumann, Markus

    Chemical communications (Cambridge, England)

    2023  Volume 59, Issue 61, Page(s) 9340–9343

    Abstract: ... ...

    Abstract 19
    Language English
    Publishing date 2023-07-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/d3cc02724d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Online ; Thesis: Functional and genomic analysis of bacterial and fungal natural products derived from the fungus-growing termite

    Schalk, Felix [Verfasser] / Pohnert, Georg [Gutachter] / Beemelmanns, Christine [Gutachter] / Spiteller, Peter [Gutachter]

    2023  

    Author's details Felix Schalk ; Gutachter: Georg Pohnert, Christine Beemelmanns, Peter Spiteller
    Keywords Biowissenschaften, Biologie ; Life Science, Biology
    Subject code sg570
    Language English
    Publisher Friedrich-Schiller-Universität Jena
    Publishing place Jena
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  9. Article ; Online: Chemical ecology of fungi

    Spiteller, Peter

    2015  

    Abstract: Fungi are widespread in nature and have conquered nearly every ecological niche. Fungi occur not only in terrestrial but also in freshwater and marine environments. Moreover, fungi are known as a rich source of secondary metabolites. Despite these facts, ...

    Abstract Fungi are widespread in nature and have conquered nearly every ecological niche. Fungi occur not only in terrestrial but also in freshwater and marine environments. Moreover, fungi are known as a rich source of secondary metabolites. Despite these facts, the ecological role of many of these metabolites is still unknown and the chemical ecology of fungi has not been investigated systematically so far. This review intends to present examples of the various chemical interactions of fungi with other fungi, plants, bacteria and animals and to give an overview of the current knowledge of fungal chemical ecology.
    Language English
    Publisher Royal Society of Chemistry
    Publishing country de
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Chemical ecology of fungi

    Spiteller, Peter

    Natural product reports. 2015 June 26, v. 32, no. 7

    2015  

    Abstract: Covering: up to the end of 2014 Fungi are widespread in nature and have conquered nearly every ecological niche. Fungi occur not only in terrestrial but also in freshwater and marine environments. Moreover, fungi are known as a rich source of secondary ... ...

    Abstract Covering: up to the end of 2014 Fungi are widespread in nature and have conquered nearly every ecological niche. Fungi occur not only in terrestrial but also in freshwater and marine environments. Moreover, fungi are known as a rich source of secondary metabolites. Despite these facts, the ecological role of many of these metabolites is still unknown and the chemical ecology of fungi has not been investigated systematically so far. This review intends to present examples of the various chemical interactions of fungi with other fungi, plants, bacteria and animals and to give an overview of the current knowledge of fungal chemical ecology.
    Keywords chemical ecology ; freshwater ; fungi ; niches ; secondary metabolites
    Language English
    Dates of publication 2015-0626
    Size p. 971-993.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ZDB-ID 2002546-4
    ISSN 1460-4752 ; 0265-0568
    ISSN (online) 1460-4752
    ISSN 0265-0568
    DOI 10.1039/c4np00166d
    Database NAL-Catalogue (AGRICOLA)

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