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  1. Book ; Online: Two-dimensional total absorption spectroscopy with conditional generative adversarial networks

    Dembski, Cade / Kuchera, Michelle P. / Liddick, Sean / Ramanujan, Raghu / Spyrou, Artemis

    2022  

    Abstract: We explore the use of machine learning techniques to remove the response of large volume $\gamma$-ray detectors from experimental spectra. Segmented $\gamma$-ray total absorption spectrometers (TAS) allow for the simultaneous measurement of individual $\ ... ...

    Abstract We explore the use of machine learning techniques to remove the response of large volume $\gamma$-ray detectors from experimental spectra. Segmented $\gamma$-ray total absorption spectrometers (TAS) allow for the simultaneous measurement of individual $\gamma$-ray energy (E$_\gamma$) and total excitation energy (E$_x$). Analysis of TAS detector data is complicated by the fact that the E$_x$ and E$_\gamma$ quantities are correlated, and therefore, techniques that simply unfold using E$_x$ and E$_\gamma$ response functions independently are not as accurate. In this work, we investigate the use of conditional generative adversarial networks (cGANs) to simultaneously unfold $E_{x}$ and $E_{\gamma}$ data in TAS detectors. Specifically, we employ a \texttt{Pix2Pix} cGAN, a generative modeling technique based on recent advances in deep learning, to treat \rawmatrix~ matrix unfolding as an image-to-image translation problem. We present results for simulated and experimental matrices of single-$\gamma$ and double-$\gamma$ decay cascades. Our model demonstrates characterization capabilities within detector resolution limits for upwards of 93% of simulated test cases.
    Keywords Nuclear Experiment ; Computer Science - Artificial Intelligence
    Publishing date 2022-06-23
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Intra- and inter-fraction relative range verification in heavy-ion therapy using filtered interaction vertex imaging.

    Hymers, Devin / Kasanda, Eva / Bildstein, Vinzenz / Easter, Joelle / Richard, Andrea / Spyrou, Artemis / Höhr, Cornelia / Mücher, Dennis

    Physics in medicine and biology

    2021  Volume 66, Issue 24

    Abstract: Heavy-ion therapy, particularly using scanned (active) beam delivery, provides a precise and highly conformal dose distribution, with maximum dose deposition for each pencil beam at its endpoint (Bragg peak), and low entrance and exit dose. To take full ... ...

    Abstract Heavy-ion therapy, particularly using scanned (active) beam delivery, provides a precise and highly conformal dose distribution, with maximum dose deposition for each pencil beam at its endpoint (Bragg peak), and low entrance and exit dose. To take full advantage of this precision, robust range verification methods are required; these methods ensure that the Bragg peak is positioned correctly in the patient and the dose is delivered as prescribed. Relative range verification allows intra-fraction monitoring of Bragg peak spacing to ensure full coverage with each fraction, as well as inter-fraction monitoring to ensure all fractions are delivered consistently. To validate the proposed filtered interaction vertex imaging (IVI) method for relative range verification, a
    MeSH term(s) Diagnostic Imaging ; Heavy Ion Radiotherapy/methods ; Humans ; Phantoms, Imaging ; Polymethyl Methacrylate ; Radiotherapy Dosage ; Silicon
    Chemical Substances Polymethyl Methacrylate (9011-14-7) ; Silicon (Z4152N8IUI)
    Language English
    Publishing date 2021-12-16
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 208857-5
    ISSN 1361-6560 ; 0031-9155
    ISSN (online) 1361-6560
    ISSN 0031-9155
    DOI 10.1088/1361-6560/ac3b33
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  3. Book ; Online: Constraining the Astrophysical p Process

    Palmisano-Kyle, Alicia / Spyrou, Artemis / DeYoung, Paul / Gastis, Panagiotis / Olivas-Gomez, Orlando / Harris, Caley / Liddick, Sean / Lyons, Stephanie / Pereira, Jorge / Richard, Andrea / Simon, Anna / Smith, Mallory / Tsantiri, Artemis / Zegers, Remco

    Cross Section Measurement of the 84Kr(p,g)85Rb Reaction in Inverse Kinematics

    2023  

    Abstract: One of the biggest questions in nuclear astrophysics is understanding where the elements come from and how they are made. This work focuses on the p process, a nucleosynthesis process that consists of a series of photodisintegration reactions responsible ...

    Abstract One of the biggest questions in nuclear astrophysics is understanding where the elements come from and how they are made. This work focuses on the p process, a nucleosynthesis process that consists of a series of photodisintegration reactions responsible for producing stable isotopes on the proton-rich side of stability. These nuclei, known as the p nuclei, cannot be made through the well-known neutron-capture processes. Currently p-process models rely heavily on theory to provide the relevant reaction rates to predict the final p-nuclei abundances and more experimental data is needed. The present work reports on an experiment performed with the SuN detector at the National Superconducting Cyclotron Laboratory, NSCL, at Michigan State University using the ReA facility to measure the $^{84}$Kr(p,$\gamma$)$^{85}$Rb reaction cross section in inverse kinematics. The reverse $^{85}$Rb($\gamma$,p)$^{84}$Kr reaction is a branching point in the p-process reaction network that was highlighted as an important reaction in sensitivity studies in the production of the $^{78}$Kr p nucleus. A new hydrogen gas target was designed and fabricated and a new analysis technique for background subtraction and efficiency calculations of the detector were developed. The experimental cross section is compared to standard statistical model calculations using the NON-SMOKER and TALYS codes.
    Keywords Nuclear Experiment
    Subject code 660
    Publishing date 2023-03-13
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Book ; Online: Intra- and Inter-Fraction Relative Range Verification in Heavy-Ion Therapy Using Filtered Interaction Vertex Imaging

    Hymers, Devin / Kasanda, Eva / Bildstein, Vinzenz / Easter, Joelle / Richard, Andrea / Spyrou, Artemis / Höhr, Cornelia / Mücher, Dennis

    2021  

    Abstract: Heavy-ion therapy, particularly using scanned (active) beam delivery, provides a precise and highly conformal dose distribution, with maximum dose deposition for each pencil beam at its endpoint (Bragg peak), and low entrance and exit dose. To take full ... ...

    Abstract Heavy-ion therapy, particularly using scanned (active) beam delivery, provides a precise and highly conformal dose distribution, with maximum dose deposition for each pencil beam at its endpoint (Bragg peak), and low entrance and exit dose. To take full advantage of this precision, robust range verification methods are required; these methods ensure that the Bragg peak is positioned correctly in the patient and the dose is delivered as prescribed. Relative range verification allows intra-fraction monitoring of Bragg peak spacing to ensure full coverage with each fraction, as well as inter-fraction monitoring to ensure all fractions are delivered consistently. To validate the proposed filtered Interaction Vertex Imaging method for relative range verification, a ${}^{16}$O beam was used to deliver 12 Bragg peak positions in a 40 mm poly-(methyl methacrylate) phantom. Secondary particles produced in the phantom were monitored using position-sensitive silicon detectors. Events recorded on these detectors, along with a measurement of the treatment beam axis, were used to reconstruct the sites of origin of these secondary particles in the phantom. The distal edge of the depth distribution of these reconstructed points was determined with logistic fits, and the translation in depth required to minimize the $\chi^2$ statistic between these fits was used to compute the range shift between any two Bragg peak positions. In all cases, the range shift was determined with sub-millimeter precision, to a standard deviation of 200 $\mu$m. This result validates filtered Interaction Vertex Imaging as a reliable relative range verification method, which should be capable of monitoring each energy step in each fraction of a scanned heavy-ion treatment plan.
    Keywords Physics - Medical Physics
    Subject code 621
    Publishing date 2021-06-16
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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