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  1. Article ; Online: D. H. Lawrence and Sexuality: Reassessing the Novels.

    Squires, Michael

    Journal of homosexuality

    2021  Volume 70, Issue 6, Page(s) 1011–1029

    Abstract: As a writer of fiction, D. H. Lawrence spent his career maneuvering between heterosexual and homosexual preferences. In order to make a living, he needed to use mainstream publishers. They encouraged his bold work but only if he censored it. What ... ...

    Abstract As a writer of fiction, D. H. Lawrence spent his career maneuvering between heterosexual and homosexual preferences. In order to make a living, he needed to use mainstream publishers. They encouraged his bold work but only if he censored it. What especially interested Lawrence were the differences between male and female orgasm-not just the mechanics but their meaning. Over his career (1910-1930) his views on orgasm evolved from simple release, to ambivalent forms of lust, to a challenging separation of responses: unfathomable silence for males and articulate expression for females. The sexes are privileged differently, and the categorical separation that Lawrence discovers is a revelation. This essay analyzes five of his most famous novels, from
    MeSH term(s) Humans ; Male ; Female ; Sexual and Gender Minorities ; Sexual Behavior ; Homosexuality ; Gender Identity ; Heterosexuality
    Language English
    Publishing date 2021-12-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 193138-6
    ISSN 1540-3602 ; 0091-8369
    ISSN (online) 1540-3602
    ISSN 0091-8369
    DOI 10.1080/00918369.2021.2010436
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1141: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Linking mobile money networks to "e-ROSCAs": An experimental study.

    Francois, Patrick / Squires, Munir

    Science advances

    2021  Volume 7, Issue 1

    Abstract: We present results from a study in the Democratic Republic of the Congo that uses mobile money networks to run rotating savings and credit associations (ROSCAs), peer-to-peer finance groups ubiquitous across the developing world. We find high rates of ... ...

    Abstract We present results from a study in the Democratic Republic of the Congo that uses mobile money networks to run rotating savings and credit associations (ROSCAs), peer-to-peer finance groups ubiquitous across the developing world. We find high rates of contribution and ROSCA success. The unexpected success of such e-ROSCAs and their potential to extend banking to the bankless poor necessitate further exploration.
    Language English
    Publishing date 2021-01-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2810933-8
    ISSN 2375-2548 ; 2375-2548
    ISSN (online) 2375-2548
    ISSN 2375-2548
    DOI 10.1126/sciadv.abc5831
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: ASO Author Reflections: Esophageal Squamous Cell Carcinoma-Still a Conundrum.

    Squires, M Hart / Salo, Jonathan C

    Annals of surgical oncology

    2021  Volume 29, Issue 2, Page(s) 1334–1335

    MeSH term(s) Carcinoma, Squamous Cell/surgery ; Esophageal Neoplasms/surgery ; Esophageal Squamous Cell Carcinoma/surgery ; Esophagectomy ; Humans
    Language English
    Publishing date 2021-10-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-021-10821-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4042: Show issues Location:
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  4. Article: Aspirin is Not for Everyone: Discharge to Non-home Facilities After Total Hip and Knee Arthroplasty Increases Risk of Venous Thromboembolism.

    McHugh, Michael / Muscatelli, Stefano / Squires, Mathieu / Honey, Nicole / Locke, Conor / Dailey, Elizabeth

    Arthroplasty today

    2024  Volume 27, Page(s) 101368

    Abstract: Background: Patients discharged to non-home facilities (NHD) after total hip arthroplasty (THA) and total knee (TKA) arthroplasty experience higher rates of adverse events and may require more aggressive venous thromboembolism (VTE) chemoprophylaxis. ... ...

    Abstract Background: Patients discharged to non-home facilities (NHD) after total hip arthroplasty (THA) and total knee (TKA) arthroplasty experience higher rates of adverse events and may require more aggressive venous thromboembolism (VTE) chemoprophylaxis. Our aim was to compare the rates of VTE in NHD patients and those discharged home (HD) after THA/TKA. Our secondary aim was to determine VTE rates within HD and NHD groups when stratified by chemoprophylactic regimen.
    Methods: A retrospective cohort of primary THA and TKA patients were stratified into HD and NHD, then allocated into groups by chemoprophylactic regimen on discharge: aspirin alone (AA), more aggressive (MA) chemoprophylaxis, and other regimens (other). The primary outcome was VTE. Rates of VTE in HD and NHD patients, as well as AA and MA regimens, were analyzed using a generalized linear regression model.
    Results: Six thousand three hundred seventy-nine patients were included with 1.03% experiencing VTE. HD had lower rates of VTE compared to NHD (0.83% vs 2.17%,
    Conclusions: NHD patients have higher rates of VTE than HD patients. However, NHD patients have significantly lower rates of VTE on MA chemoprophylaxis compared to those on AA. Providers should consider prescribing MA VTE chemoprophylaxis for NHD patients. Prospective, randomized studies are necessary to confirm these recommendations.
    Language English
    Publishing date 2024-03-31
    Publishing country United States
    Document type Journal Article
    ISSN 2352-3441
    ISSN 2352-3441
    DOI 10.1016/j.artd.2024.101368
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: scMultiSim: simulation of single cell multi-omics and spatial data guided by gene regulatory networks and cell-cell interactions.

    Li, Hechen / Zhang, Ziqi / Squires, Michael / Chen, Xi / Zhang, Xiuwei

    Research square

    2023  

    Abstract: Simulated single-cell data is essential for designing and evaluating computational methods in the absence of experimental ground truth. Existing simulators typically focus on modeling one or two specific biological factors or mechanisms that affect the ... ...

    Abstract Simulated single-cell data is essential for designing and evaluating computational methods in the absence of experimental ground truth. Existing simulators typically focus on modeling one or two specific biological factors or mechanisms that affect the output data, which limits their capacity to simulate the complexity and multi-modality in real data. Here, we present scMultiSim, an
    Language English
    Publishing date 2023-09-19
    Publishing country United States
    Document type Preprint
    DOI 10.21203/rs.3.rs-3301625/v1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Clinical outcomes after bracing for vertebral compression fractures: a systematic review and meta-analysis of randomized trials.

    Squires, Mathieu / Green, Jordan Howard / Patel, Rakesh / Aleem, Ilyas

    Journal of spine surgery (Hong Kong)

    2023  Volume 9, Issue 2, Page(s) 139–148

    Abstract: Background: Vertebral compression fractures are common and result in significant pain and loss of function. Treatment strategy, however, remains controversial. We conducted a meta-analysis of randomized trials to elucidate the impact of bracing on these ...

    Abstract Background: Vertebral compression fractures are common and result in significant pain and loss of function. Treatment strategy, however, remains controversial. We conducted a meta-analysis of randomized trials to elucidate the impact of bracing on these injuries.
    Methods: A comprehensive literature review utilizing Embase, OVID MEDLINE, and the Cochrane Library was performed to identify randomized trials evaluating brace therapy for adult patients with thoracic and lumbar compression fractures. Two independent reviewers assessed the eligibility of studies and risk of bias. The primary assessed outcome was pain after injury. Secondary outcomes were function, quality of life, opioid use, and kyphotic progression [anterior vertebral body compression percentage (AVBCP)]. Continuous variables were analyzed using mean differences and standardized mean differences, and dichotomous variables were analyzed using odds ratios in random-effects models. GRADE criteria were applied.
    Results: Of 1,502 articles, a total of 3 studies with 447 patients (96% female) were included. Fifty-four patients were managed without a brace, and 393 with a brace (195 rigid, 198 soft). At 3 to 6 months post-injury, rigid bracing resulted in significantly less pain compared to no brace (SMD =-1.32, 95% CI: -1.89 to -0.76, P<0.05, I
    Conclusions: Moderate quality evidence demonstrates rigid bracing of vertebral compression fractures may decrease pain up to 6 months post-injury, though there is no difference in radiographic parameters, opioid use, function, or quality of life at short- or long-term follow-up. No difference was found between rigid and soft bracing; therefore, soft bracing may be an adequate alternative.
    Language English
    Publishing date 2023-03-17
    Publishing country China
    Document type Journal Article
    ZDB-ID 2874556-5
    ISSN 2414-4630 ; 2414-469X
    ISSN (online) 2414-4630
    ISSN 2414-469X
    DOI 10.21037/jss-22-78
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: scMultiSim: simulation of multi-modality single cell data guided by cell-cell interactions and gene regulatory networks.

    Li, Hechen / Zhang, Ziqi / Squires, Michael / Chen, Xi / Zhang, Xiuwei

    Research square

    2023  

    Abstract: Simulated single-cell data is essential for designing and evaluating computational methods in the absence of experimental ground truth. Existing simulators typically focus on modeling one or two specific biological factors or mechanisms that affect the ... ...

    Abstract Simulated single-cell data is essential for designing and evaluating computational methods in the absence of experimental ground truth. Existing simulators typically focus on modeling one or two specific biological factors or mechanisms that affect the output data, which limits their capacity to simulate the complexity and multi-modality in real data. Here, we present scMultiSim, an
    Language English
    Publishing date 2023-03-15
    Publishing country United States
    Document type Preprint
    DOI 10.21203/rs.3.rs-2675530/v1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: An Investigation of Hiccups.

    Squires, Melissa / Sribnick, Eric A

    Pediatric neurology

    2020  Volume 106, Page(s) 70–71

    MeSH term(s) Adolescent ; Central Nervous System Vascular Malformations/complications ; Central Nervous System Vascular Malformations/diagnostic imaging ; Central Nervous System Vascular Malformations/pathology ; Central Nervous System Vascular Malformations/surgery ; Cervical Cord/diagnostic imaging ; Cervical Cord/pathology ; Cervical Cord/surgery ; Hiccup/etiology ; Humans ; Magnetic Resonance Imaging ; Male ; Medulla Oblongata/diagnostic imaging ; Medulla Oblongata/pathology ; Medulla Oblongata/surgery ; Reflex, Abnormal
    Language English
    Publishing date 2020-02-04
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 639164-3
    ISSN 1873-5150 ; 0887-8994
    ISSN (online) 1873-5150
    ISSN 0887-8994
    DOI 10.1016/j.pediatrneurol.2019.12.012
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    Zs.A 2260: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Is the NHS a business?

    Squires, Mike

    The British journal of general practice : the journal of the Royal College of General Practitioners

    2014  Volume 64, Issue 622, Page(s) 257–258

    MeSH term(s) Commerce/organization & administration ; Economic Competition ; Humans ; Interinstitutional Relations ; Organizational Innovation ; Quality of Health Care ; State Medicine/economics ; State Medicine/organization & administration ; United Kingdom
    Language English
    Publishing date 2014-04-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 1043148-2
    ISSN 1478-5242 ; 0035-8797 ; 0960-1643
    ISSN (online) 1478-5242
    ISSN 0035-8797 ; 0960-1643
    DOI 10.3399/bjgp14X679886
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 576: Show issues Location:
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  10. Article ; Online: Lithium heparin interference in the Abbott enzymatic creatinine assay: the significance of under-filled tubes.

    Squires, Maria / Wise, Helen / Holmes, Heather / Hadfield, Katie

    Annals of clinical biochemistry

    2021  Volume 58, Issue 6, Page(s) 653–656

    Abstract: Background: Spuriously high results using the Abbott Architect enzymatic creatinine assay were noted to be particularly associated with very small sample volumes. This led us to query the effect of under-filling lithium heparin tubes on the measured ... ...

    Abstract Background: Spuriously high results using the Abbott Architect enzymatic creatinine assay were noted to be particularly associated with very small sample volumes. This led us to query the effect of under-filling lithium heparin tubes on the measured enzymatic creatinine result.
    Methods: Blood was provided by 5 laboratory personnel and then decanted into 5 x1.2 mL Sarstedt S-Monovette tubes, giving final blood volumes of 200, 400, 600, 800 and 1200 
    Results: Increasing degrees of under-fill were associated with greater over-estimation of creatinine using the Abbott enzymatic assay, but no difference was noted using Jaffe methodology on the same platform or enzymatic assays provided by Roche or Beckman. On average, creatinine was 40.6% (+27.7 
    Conclusions: Lithium heparin directly interferes in the Abbott Architect enzymatic creatinine assay. Under-filling lithium heparin tubes can lead to clinically significant over-estimation of creatinine results by this assay. Users of this assay should be aware of the potential for spurious results in small sample volumes collected into lithium heparin tubes and implement robust procedures for identifying and reporting results on these samples.
    MeSH term(s) Creatinine ; Enzyme Assays ; Hematologic Tests ; Heparin ; Humans ; Lithium
    Chemical Substances Heparin (9005-49-6) ; Lithium (9FN79X2M3F) ; Creatinine (AYI8EX34EU)
    Language English
    Publishing date 2021-08-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 390309-6
    ISSN 1758-1001 ; 0004-5632
    ISSN (online) 1758-1001
    ISSN 0004-5632
    DOI 10.1177/00045632211040673
    Database MEDical Literature Analysis and Retrieval System OnLINE

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