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Article ; Online: Serpent strikes, sapien sways: A rare case of bilateral cerebellar infarct following viper bite.

Srinath, K M / Sethi, Mahim / Madhu, B / Prasad, M C / Sangappa, Sunila B

2024 Volume 23, Issue 1, Page(s) 104–106

Abstract: Ischemic stroke following snake bite is rare. We report a posterior circulation infarct involving bilateral cerebellum and occipital lobe following Russell's viper bite in a previously healthy individual. A 50 years old healthy individual, soon after ... ...

Abstract	Ischemic stroke following snake bite is rare. We report a posterior circulation infarct involving bilateral cerebellum and occipital lobe following Russell's viper bite in a previously healthy individual. A 50 years old healthy individual, soon after being bitten by the Russel viper on the left foot he developed pain and swelling followed by drooping of eyelids, slurring of speech and giddiness with multiple episodes of vomiting. The patient was administered ASV as well as neostigmine and atropine injections. Following this, the neurological manifestations resolved except dysarthria. CT brain study done was normal. On day 2 of hospitalization, he developed left cerebellar signs (positive finger nose finger test, rebound phenomenon, dysdiadochokinesia, a positive heel shin test). Subsequently, an MRI with MR angiogram was done which showed acute infarcts in bilateral cerebellar hemispheres, with the left superior cerebellar peduncle showing restricted diffusion and low ADC values. Ischemic infarction following viper envenomation has been described by only few authors. In majority of the cases reported, ischemic infarction involved the anterior circulation. The possible mechanisms of infarction in this scenario are discussed. Patient was treated with anti-snake venom and showed a good recovery. Early imaging and early treatment with anti-snake venom is important for a favourable outcome.
MeSH term(s)	Male ; Animals ; Humans ; Middle Aged ; Snake Bites/complications ; Snake Bites/therapy ; Brain Ischemia ; Magnetic Resonance Imaging ; Daboia ; Infarction ; Antivenins
Chemical Substances	Antivenins
Language	English
Publishing date	2024-02-15
Publishing country	India
Document type	Case Reports
ZDB-ID	2165792-0
ISSN	0975-5764 ; 0975-5764
ISSN (online)	0975-5764
ISSN	0975-5764
DOI	10.4103/aam.aam_44_23
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Response to Wei Y-S, Liu W-L, Bai R, Li D-H, Zhao Z-Q, Wang Y, et al. The use of a transolecranon pin joystick technique in the treatment of multidirectionally unstable supracondylar humeral fractures in children. J Pediatr Orthop B 2020; 29:452-457.

Jeevannavar, Santosh S / Srinath, K M / Patil, Naveenkumar / Shetty, Deekshith

Journal of pediatric orthopedics. Part B

2021 Volume 31, Issue 1, Page(s) e107

Language	English
Publishing date	2021-11-30
Publishing country	United States
Document type	Journal Article
ISSN	1473-5865
ISSN (online)	1473-5865
DOI	10.1097/BPB.0000000000000904
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The ambulatory blood pressure monitoring among obese and nonobese diabetes mellitus patients.

Mathews, Hella Fiona / Kumar, Sunil / Madhu, B / Gona, Oliver Joel / Srinath, K M

Annals of African medicine

2022 Volume 21, Issue 3, Page(s) 255–261

Abstract: Background: Obesity and diabetes mellitus are two major factors related with the risk of metabolic syndrome and cardiovascular diseases. Co-existing hypertension with diabetes mellitus and obesity has poor prognosis for cardiovascular diseases. ... ...

Abstract	Background: Obesity and diabetes mellitus are two major factors related with the risk of metabolic syndrome and cardiovascular diseases. Co-existing hypertension with diabetes mellitus and obesity has poor prognosis for cardiovascular diseases. Ambulatory blood pressure monitoring (ABPM) correlates more closely to target organ damage than clinic blood pressure. Objectives: The objective of the study is to assess and compare ABPM pattern among obese and nonobese diabetes mellitus patients. Materials and methods: A cross-sectional study was conducted among fifty obese and fifty nonobese diabetic patients who were classified based on their body mass index as per the WHO criterion. The clinical blood pressure measurements were measured on each subject using a digital sphygmomanometer, and 24 h ABPM was done and ABPM parameters such as dipping pattern, 24 h systolic blood pressure (SBP), diastolic blood pressure (DBP), Mean SBP, mean DBP, diurnal variability of SBP, DBP, Mean arterial pressure, pulse pressure, SD systole (Standard Deviation systole), SD diastole, white coat hypertension was derived and compared between the two groups. Results: Around 37 (74%) obese and 18 (36%) nonobese showed non dipping pattern in SBP and 28 (66.7%) of obese and 14 (33.3%) of nonobese showed a nondipping pattern in DBP and was found to be statistically significant (P < 0.001). On comparison between normotensive obese and normotensive nonobese, it was found that SBP non dipping pattern18 (67%) versus 9 (29%) and DBP nondipping pattern 12 (45%) versus 5 (16%) was statistically significant with P = 0.004, 0.016, respectively. Conclusion: Obese diabetes mellitus subjects had altered ABPM parameters and increased prevalence of nondipping status. In addition, obese diabetic patients who did not give prior history of hypertension were also found to have higher nondipping SBP and DBP patterns.
MeSH term(s)	Blood Pressure/physiology ; Blood Pressure Monitoring, Ambulatory ; Cardiovascular Diseases ; Circadian Rhythm/physiology ; Cross-Sectional Studies ; Diabetes Mellitus/epidemiology ; Humans ; Hypertension/complications ; Hypertension/epidemiology ; Obesity/complications ; Obesity/epidemiology ; Risk Factors
Language	English
Publishing date	2022-10-06
Publishing country	India
Document type	Journal Article
ZDB-ID	2165792-0
ISSN	0975-5764 ; 0975-5764
ISSN (online)	0975-5764
ISSN	0975-5764
DOI	10.4103/aam.aam_65_21
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Comparison of prevalence of life style risk factors and 10 year risk of CVD event among rural and tribal population of Kollegal Taluk, Chamrajanagar district, South India.

Madhu, B / Prathyusha, K / Prakruthi, P / Srinath, K M

Diabetes & metabolic syndrome

2019 Volume 13, Issue 5, Page(s) 2961–2966

Abstract: Context: Cardiovascular diseases have been recognized as leading cause of death. Three-fourths of CVD deaths occur in low and middle income countries. Surveillance of CVD risk factors is a key strategy for effective CVD prevention.: Aims: To identify ...

Abstract	Context: Cardiovascular diseases have been recognized as leading cause of death. Three-fourths of CVD deaths occur in low and middle income countries. Surveillance of CVD risk factors is a key strategy for effective CVD prevention. Aims: To identify the extent of CVD risk factors and 10 year risk of developing Cardiovascular Disease events among rural and tribal population. Subjects and methods: This community based cross sectional study was conducted on a total of 482 rural and 415 tribal subjects aged above 30 years from Kollegal taluk, Chamrajanagar, Karnataka, India. Tobacco and alcohol consumption, BMI, blood pressure and capillary blood glucose were estimated. WHO/ISH risk prediction chart was used to predict 10 year risk of MI/stroke. Results: Tobacco consumption was 15.4% (rural) and 90.8% (tribal). Alcohol consumption was 10.8% (rural) and 21.9% (tribal), Obesity was 40.2% (rural) and 14.0% (tribal). Prevalence of Hypertension was 49.8% (rural) and 32.2% (Tribal) and diabetes 8.3% (rural) and 2.9% (tribal). Nearly one fourth of the population are at moderate risk (10-30%) and one tenth are at high risk (30%) of MI/Stroke within 10 years. Conclusions: High prevalence of tobacco consumption among tribal and high prevalence of hypertension and diabetes among rural predisposes 10% of population to moderate to high risk of stroke/MI within 10 years.
MeSH term(s)	Adult ; Biomarkers/analysis ; Blood Pressure ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/etiology ; Cross-Sectional Studies ; Diabetes Mellitus/physiopathology ; Female ; Follow-Up Studies ; Humans ; Hypertension/complications ; India/epidemiology ; Life Style ; Male ; Middle Aged ; Obesity/complications ; Prevalence ; Prognosis ; Risk Factors ; Rural Population/statistics & numerical data
Chemical Substances	Biomarkers
Language	English
Publishing date	2019-08-02
Publishing country	Netherlands
Document type	Comparative Study ; Journal Article
ZDB-ID	2273766-2
ISSN	1878-0334 ; 1871-4021
ISSN (online)	1878-0334
ISSN	1871-4021
DOI	10.1016/j.dsx.2019.07.056
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Article ; Online: Diabetic self care practices in rural Mysuru, Southern Karnataka, India - A need for Diabetes Self Management Educational (DSME) program.

Srinath, K M / Basavegowda, Madhu / Tharuni, Nandarula Sai

Diabetes & metabolic syndrome

2017 Volume 11 Suppl 1, Page(s) S181–S186

Abstract: Context: Diabetes and its complications are the leading cause of morbidity and mortality in the world. Self care has emerged as a crucial element in the management of diabetes and a key factor associated with the quality of diabetic care.: Aims: The ... ...

Abstract	Context: Diabetes and its complications are the leading cause of morbidity and mortality in the world. Self care has emerged as a crucial element in the management of diabetes and a key factor associated with the quality of diabetic care. Aims: The purpose of the study was to assess the self care activities of patients with Type II diabetes mellitus in a rural area of Mysuru district. Settings and design: A community based cross sectional descriptive study was carried out among 400 diabetic patients in rural Mysore. Methods and material: Self care Activities (Diet, exercise, self blood glucose monitoring, medication, foot care, smoking) were assessed using a pre designed and tested questionnaire. Statistical analysis used: Relevant descriptive analysis like percentages is carried out using SPSS version 22.0. Results: Most of the diabetic patients had good compliance for medication (92.5%), followed by 72% for diabetic diet. Only 27.75% of the diabetic patients participated in walking, 24.25% practised foot care, blood glucose monitoring by 24.75% and only 25.5% of them were current smokers. Conclusions: The rural diabetic patients are more adherent and compliant to medication and diabetic diet and less compliant to physical activity, foot care and self glucose monitoring.
MeSH term(s)	Adult ; Aged ; Blood Glucose Self-Monitoring ; Community-Based Participatory Research ; Cross-Sectional Studies ; Diabetes Mellitus, Type 2/prevention & control ; Exercise ; Female ; Follow-Up Studies ; Humans ; India/epidemiology ; Male ; Middle Aged ; Patient Compliance ; Patient Education as Topic ; Prognosis ; Rural Population ; Self Care ; Surveys and Questionnaires
Language	English
Publishing date	2017-11
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2273766-2
ISSN	1878-0334 ; 1871-4021
ISSN (online)	1878-0334
ISSN	1871-4021
DOI	10.1016/j.dsx.2016.12.029
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Article: Sub-clinical Hypothyroidism in Type 2 Diabetes Mellitus Patients in a Tertiary Care Hospital, Mysore.

Galag, Srinath C / Rajalashmi, R / Srinath, K M / Madhu, B

Indian journal of physiology and pharmacology

2016 Volume 60, Issue 3, Page(s) 255–259

MeSH term(s)	Adult ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/epidemiology ; Female ; Humans ; Hypothyroidism/complications ; Hypothyroidism/epidemiology ; India/epidemiology ; Male
Language	English
Publishing date	2016-07
Publishing country	India
Document type	Journal Article
ZDB-ID	604352-5
ISSN	0019-5499
ISSN	0019-5499
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Article: Factors Contributing to Development and Reversal of LVH: A Pilot Study.

Ramaswamy, Prasanna Kumar Hassan / Bhanukumar, M / Hathur, Basavanagowdappa / Shashidhara, K C / Srinath, K M

Journal of clinical and diagnostic research : JCDR

2016 Volume 10, Issue 5, Page(s) OC17–20

Abstract: Introduction: Left Ventricular Hypertrophy (LVH) often reflects as a physiological adaptation to chronic pressure overload. It has been identified as a strong independent risk factor of all-cause mortality and adverse cardiac events. Since not all ... ...

Abstract	Introduction: Left Ventricular Hypertrophy (LVH) often reflects as a physiological adaptation to chronic pressure overload. It has been identified as a strong independent risk factor of all-cause mortality and adverse cardiac events. Since not all subjects with hypertension develop LVH, understanding the clinical factors contributing to the development of LVH and the appropriate diagnostic and treatment strategies may help clinicians in conducting more definitive evaluation and managing the disease effectively. Aim: To assess the incidence of LVH in hypertensive subjects and the factors influencing its development and reversal. The study also evaluated the most effective diagnostic technique and therapy that could improve the disease symptoms and prognosis. Materials and methods: The prospective study, conducted at Jagadguru Sri Shivarathreeshwara (JSS) Medical College JSS University, Mysore, India, included 50 patients with hypertension. Detailed history of the recruited subjects was collected from patient records and through physical examination. Demographic and clinical characteristics such as age, gender, BMI, and stage of hypertension (stage I HTN and stage II HTN) were also obtained. Funduscopic examination was done for all patients for evidence of hypertensive retinopathy. Echocardiography (ECHO), electrocardiography (ECG), and chest X-Ray were used for detection of LVH. The patients were reviewed after six months and reassessment of LVH was carried out. Statistical analysis was conducted using SPSS software and R 3.2 package. Results: Angiotensin-Converting Enzyme (ACE) inhibitors were found to be more effective in the treatment of LVH when compared to calcium channel blockers and beta blockers. ECHO was found to be the best method to diagnose LVH. In patients with stage I HTN, 47.1% had normal LVM. Around 53% of the subjects with stage I HTN and all with stage II HTN had abnormal LVM. Retinal changes were noted in 96.2% of abnormal LVM patients and 50% of normal LVM patients. A positive association between BMI and LVH (OR: 1.39) was also noted. Conclusion: BMI may positively influence LVH regression. The presence of retinopathy, in addition to LVH, suggests an increased chance of regression with anti-hypertensive treatment.
Language	English
Publishing date	2016-05-01
Publishing country	India
Document type	Journal Article
ZDB-ID	2775283-5
ISSN	0973-709X ; 2249-782X
ISSN (online)	0973-709X
ISSN	2249-782X
DOI	10.7860/JCDR/2016/19747.7767
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Article ; Online: Quality of diabetic care in an urban slum area of Mysore: A community based study.

Madhu, B / Srinath, K M / Chandresh, Swathi / Ashok, N C / Basavanagowdappa, H / Rama, H V

Diabetes & metabolic syndrome

2016 Volume 10, Issue 2 Suppl 1, Page(s) S135–8

MeSH term(s)	Adult ; Aged ; Blood Glucose ; Cross-Sectional Studies ; Diabetes Complications/psychology ; Diabetes Mellitus/psychology ; Diabetes Mellitus/therapy ; Female ; Humans ; India ; Male ; Middle Aged ; Patient Compliance ; Poverty Areas ; Quality of Health Care ; Socioeconomic Factors
Chemical Substances	Blood Glucose
Language	English
Publishing date	2016-04
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2273766-2
ISSN	1878-0334 ; 1871-4021
ISSN (online)	1878-0334
ISSN	1871-4021
DOI	10.1016/j.dsx.2016.03.014
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Article: Patient Self-reported quality of life assessment in Type 2 diabetes mellitus: A pilot study.

PrasannaKumar, H R / Mahesh, M G / Menon, V B / Srinath, K M / Shashidhara, K C / Ashok, P

Nigerian journal of clinical practice

2018 Volume 21, Issue 3, Page(s) 343–349

Abstract: Background: Quality of life (QoL) is an important outcome measure to assess the diabetic care and is increasingly replacing the traditional indicators of health.: Aim: The aim is to evaluate the QoL in patients with type 2 diabetes mellitus (DM) ... ...

Abstract	Background: Quality of life (QoL) is an important outcome measure to assess the diabetic care and is increasingly replacing the traditional indicators of health. Aim: The aim is to evaluate the QoL in patients with type 2 diabetes mellitus (DM) using a third generation individualized QoL instrument like an audit of diabetes-dependent QoL (ADDQoL) questionnaire and to determine the predictors. Materials and methods: Patients who met the inclusion and exclusion criteria were recruited from a tertiary care hospital by convenience sampling. Sociodemographic and other relevant details were collected from the study patients, and ADDQoL questionnaire were administered to them. Results: A total of 200 patients were included in the study among which 66% of patients had uncontrolled type 2 DM as suggested by their glycated hemoglobin (HbA1c) values. The mean QoL score was 0.07 (0.91) and diabetes-dependent QoL was -1.33 (0.58). Approximately 38% were associated with poor health-related QoL with a mean average weighted impact score of -0.51 (0.51). Most frequently affected life domain was the freedom to eat. A positive correlation was observed between QoL and gender, age, domicile, education status, occupation, family structure, duration of type 2 DM, HbA1c, insulin treatment, and the presence of comorbidities. Conclusion: The study highlights the impact of type 2 DM on QoL. Improving QoL of type 2 diabetic patients is important and knowledge of these preventable risk factors help to implement strategies to better management of type 2 DM and ultimately improve therapeutic outcome.
MeSH term(s)	Adult ; Aged ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/psychology ; Diabetes Mellitus, Type 2/therapy ; Female ; Humans ; Hypoglycemic Agents/therapeutic use ; India ; Insulin/therapeutic use ; Male ; Middle Aged ; Patient Reported Outcome Measures ; Pilot Projects ; Quality of Life/psychology ; Reproducibility of Results ; Risk Factors ; Self Report ; Surveys and Questionnaires/standards
Chemical Substances	Hypoglycemic Agents ; Insulin
Language	English
Publishing date	2018-02-02
Publishing country	India
Document type	Journal Article
ZDB-ID	1458330-6
ISSN	1119-3077
ISSN	1119-3077
DOI	10.4103/njcp.njcp_433_16
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Article ; Online: Pattern of vitamin D status in prediabetic individuals

Srinath K. M. / Shashidhara K. C. / Rajeev Reddy G. / Madhu Basavegowda / Kishaloy Debnath / Mahesh M.G.

International Journal of Research in Medical Sciences, Vol 4, Iss 4, Pp 1010-

a case control study at tertiary hospital in South India

2016 Volume 1015

Abstract: Background: Role of vitamin D in the regulation of calcium metabolism is well established. Vitamin D deficiency has been linked to impaired glucose tolerance and type 2 DM in humans. There is a limited available data on the relationship of vitamin D ... ...

Abstract	Background: Role of vitamin D in the regulation of calcium metabolism is well established. Vitamin D deficiency has been linked to impaired glucose tolerance and type 2 DM in humans. There is a limited available data on the relationship of vitamin D insufficiency/deficiency with glucose homeostasis among prediabetic individuals in South Indian population. Hence we examined serum 25(OH) D3 concentration among prediabetics. The objective of this study is to evaluate prevalence of vitamin D deficiency in prediabetics and to study any correlation between vitamin D and BMI, FBS and PPBS among prediabetics. Methods: A case control study was carried out among 40 prediabetics and controls, after obtaining consent from subjects and clearance from institutional ethics committee. Serum vitamin D levels were measured by radioimmunoassay in both groups. Statistical analysis was done using and ldquo;t and rdquo; test and Pearson correlation co-efficient (r). Results: Vitamin D levels less than 20 ng/ml were found in 72.5% of cases and 35% of controls. 5% of the cases and 12.5% of the controls had vitamin D above 30 ng/ml and this difference was statistically significant. Mean vitamin D levels in cases and controls was 17.09+/-5.89 ng/ml and 23.67+/-11.02 ng/ml respectively (P<0.05). A significant inverse correlation was observed between vitamin D levels and body mass index (r=-0.274; p=0.014); random blood sugar (r=-0.35; p=0.001); fasting blood sugar (r=-0.328; p=0.003); post prandial blood sugar (r=-0.276; p=0.013). Conclusions: High prevalence of hypovitaminosis D exists among prediabetics and there is significant inverse correlation between BMI, FBS, PPBS and vitamin D levels. Hence, a prospective study covering large pre-diabetic individuals is essential to confirm the findings. [Int J Res Med Sci 2016; 4(4.000): 1010-1015]
Keywords	Vitamin D ; Vitamin D deficiency ; Prediabetes ; Type 2 DM ; Prevalence ; Medicine (General) ; R5-920 ; Medicine ; R
Subject code	360
Language	English
Publishing date	2016-04-01T00:00:00Z
Publisher	Medip Academy
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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