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  1. Article ; Online: Management of Arteriovenous Malformations - A Sisyphean Task?

    Srinivas, Dwarakanath

    Neurology India

    2022  Volume 70, Issue 6, Page(s) 2340–2342

    MeSH term(s) Humans ; Intracranial Arteriovenous Malformations
    Language English
    Publishing date 2022-12-19
    Publishing country India
    Document type Editorial
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.364081
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Prof Ravi Marthanda Varma - A Visionary par Excellence.

    Srinivas, Dwarakanath

    Neurology India

    2022  Volume 70, Issue 5, Page(s) 1767–1768

    Language English
    Publishing date 2022-11-09
    Publishing country India
    Document type Journal Article
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.359299
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Conference proceedings: Expanded Endoscopic Endonasal Approach to Occipital Condyle: A Morphometric Study in Indian Cadavers

    Shah, Keyur Dr G. / Srinivas, Dwarakanath

    Journal of Neurological Surgery Part B: Skull Base

    2024  Volume 85, Issue S 01

    Event/congress 33rd Annual Meeting North American Skull Base Society, Atlanta Marriott Marquis Atlanta, Georgia, United States, 2024-02-16
    Keywords expanded endoscopic endonasal approach ; occipital Condyle ; morphometry ; Indian cadavers
    Language English
    Publishing date 2024-02-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 2654269-9
    ISSN 2193-634X ; 2193-6331
    ISSN (online) 2193-634X
    ISSN 2193-6331
    DOI 10.1055/s-0044-1780214
    Database Thieme publisher's database

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  4. Article ; Online: Dementia in Parkinson's disease after subthalamic deep brain stimulation - Is it inevitable and predictable?

    Srinivas, Dwarakanath

    Neurology India

    2019  Volume 67, Issue 2, Page(s) 395–396

    MeSH term(s) Deep Brain Stimulation ; Dementia ; Humans ; Parkinson Disease ; Subthalamic Nucleus
    Language English
    Publishing date 2019-05-07
    Publishing country India
    Document type Journal Article ; Comment
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.258018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Micro-surgical Clipping of a Right Paraclinoid Aneurysm with a "Rescue" STA-MCA Bypass.

    Tyagi, Gaurav / Nadeem, Mohammed / Beniwal, Manish / Srinivas, Dwarakanath

    Neurology India

    2023  Volume 71, Issue 5, Page(s) 884–887

    MeSH term(s) Humans ; Cerebral Revascularization ; Intracranial Aneurysm/surgery ; Middle Cerebral Artery/surgery ; Temporal Arteries
    Language English
    Publishing date 2023-11-01
    Publishing country India
    Document type Journal Article ; Video-Audio Media
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.388058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Role of Optical Coherence Tomography in Predicting Visual Outcome after Surgery for Sellar and Supra-Sellar Tumors.

    Singha, Souvik / Beniwal, Manish / Mailankody, Pooja / Battu, Rajani / Saini, Jitender / Tyagi, Gaurav / Srinivas, Dwarakanath

    Neurology India

    2024  Volume 72, Issue 1, Page(s) 50–57

    Abstract: Background: Almost one-fifth of patients undergoing surgery for sellar/supra-sellar tumors do not gain a significant improvement in their vision. Various methods have been described to predict prospective visual outcomes in them, although they lack ... ...

    Abstract Background: Almost one-fifth of patients undergoing surgery for sellar/supra-sellar tumors do not gain a significant improvement in their vision. Various methods have been described to predict prospective visual outcomes in them, although they lack uniformity.
    Objective: The study was conducted to predict visual outcomes following surgery for sellar and supra-sellar tumors compressing the anterior optic pathway based on pre-operative optical coherence tomography (OCT) parameters.
    Methods and materials: This was a record-based observational descriptive longitudinal study done in a tertiary care center in India. Thirty-seven patients (74 eyes) diagnosed with sellar supra-sellar lesions were included in the study. Patients' ophthalmic evaluations, done pre-operatively and 3 months post-operatively, were reviewed. Spectral-domain OCT and segmentation were done using the automated segmentation technology of Spectralis software. The thickness of the respective layers was measured.
    Results and conclusions: The mean age of the study population was 42.68 years. Eyes with a pre-operative visual acuity component of VIS (visual impairment score) ≤61, pre-operative ganglion cell layer thickness ≥26.31 um, a pre-operative inner plexiform layer thickness of ≥25.69 um, a pre-operative ganglion cell inner plexiform layer thickness of 52.00 um, pre-operative ganglion cell complex thickness ≥84.47 μm, and a pre-operative inner retinal layer thickness of ≥205.25 μm were more likely to have an improved visual outcome. Eyes with a pre-operative duration of visual symptoms of ≥15 months, VIS ≥126.50, a pre-operative decimal visual acuity of <0.035, a pre-operative visual field index of ≤8%, a pre-operative macular thickness of ≤287.06 um, a pre-operative macular RNFL (retinal nerve fiber layer) thickness ≤66.00 μm, and a pre-operative peri-papillary RNFL thickness ≤64.62 μm were unlikely to have visual improvement.
    MeSH term(s) Humans ; Adult ; Tomography, Optical Coherence ; Longitudinal Studies ; Prospective Studies ; Skull Base Neoplasms ; Retina/diagnostic imaging ; Retina/surgery
    Language English
    Publishing date 2024-02-29
    Publishing country India
    Document type Observational Study ; Journal Article
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/neurol-india.Neurol-India-D-23-00654
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Prevalence and predictors of preoperative cardiac autonomic dysfunction among elective neurosurgical patients: A prospective observational study.

    Sangeetha, R P / Chakrabarti, Dhritiman / Sriganesh, Kamath / Mahendranath, Musumur / Sathyaprabha, T N / Srinivas, Dwarakanath

    Indian journal of anaesthesia

    2024  Volume 68, Issue 4, Page(s) 380–386

    Abstract: Background and aims: The autonomic nervous system (ANS) is cardinal for systemic homeostasis. Autonomic dysfunction is prevalent in as high as 65% of patients presenting for cardiac surgery in the Indian scenario. Pre-existing cardiac autonomic ... ...

    Abstract Background and aims: The autonomic nervous system (ANS) is cardinal for systemic homeostasis. Autonomic dysfunction is prevalent in as high as 65% of patients presenting for cardiac surgery in the Indian scenario. Pre-existing cardiac autonomic dysfunction (CAD) in surgical patients can accentuate perioperative haemodynamic fluctuations during stressful intraoperative events, predispose to adverse cardiac events, and contribute to morbidity and mortality. The prevalence and predictors of CAD in the elective neurosurgical population are unknown in the Indian scenario. The current study was conducted to bridge this knowledge gap.
    Methods: In this single-centre prospective observational study conducted at a tertiary care neurosciences centre, among 400 consenting adult patients of either gender, between 18 and 80 years of age, undergoing elective neurosurgery, the preoperative ANS function at the bedside was assessed as the primary outcome measure. The ANS status was evaluated using ANSiscope™-derived indices of heart rate variability. The diagnosis of CAD was made when the ANS index exceeded a threshold of 13.5. Data regarding predictors of CAD were collected from patient records as the secondary outcome measure. Statistical analysis was done using the R software. A
    Results: The prevalence of preoperative CAD in our study population was 79.7% (319/400 patients). None of the demographic and baseline clinical characteristics we studied predicted CAD in our study.
    Conclusion: We observed a significant prevalence of preoperative CAD among elective neurosurgical patients. None of the parameters we evaluated predicted CAD in our study.
    Language English
    Publishing date 2024-03-13
    Publishing country India
    Document type Journal Article
    ZDB-ID 412570-8
    ISSN 0019-5049
    ISSN 0019-5049
    DOI 10.4103/ija.ija_722_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Impact of Deep Brain Stimulation on Non-Motor Symptoms in Parkinson's Disease.

    Mishra, Tanaya / Kamble, Nitish / Bhattacharya, Amitabh / Yadav, Ravi / Srinivas, Dwarakanath / Pal, Pramod Kumar

    Journal of movement disorders

    2024  Volume 17, Issue 2, Page(s) 245–247

    Language English
    Publishing date 2024-03-13
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3021788-X
    ISSN 2093-4939 ; 2005-940X
    ISSN (online) 2093-4939
    ISSN 2005-940X
    DOI 10.14802/jmd.23247
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Compulsive programming in a patient with deep brain stimulation for obsessive-compulsive disorder.

    Ganaraja, Sneha V / Sharma, Lavanya P / Arumugham, Shyam Sundar / Vaishya, Sandeep / Srinivas, Dwarakanath

    Asian journal of psychiatry

    2024  Volume 95, Page(s) 103980

    MeSH term(s) Humans ; Obsessive-Compulsive Disorder/therapy ; Deep Brain Stimulation/methods ; Male ; Adult ; Treatment Outcome
    Language English
    Publishing date 2024-02-24
    Publishing country Netherlands
    Document type Letter ; Case Reports
    ZDB-ID 2456678-0
    ISSN 1876-2026 ; 1876-2018
    ISSN (online) 1876-2026
    ISSN 1876-2018
    DOI 10.1016/j.ajp.2024.103980
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Prognostic factors and outcomes in WHO Grade 1 and Grade 2 intracranial meningiomas - 5 year institutional experience.

    Nadeem, Mohammed / Goyal-Honavar, Abhijit / Sravya, Palavalasa / Beniwal, Manish / Santosh, Vani / Srinivas, Dwarakanath

    World neurosurgery

    2024  

    Abstract: Background: Meningiomas are the most frequent primary intracranial tumour. While histological grade and grade of excision are established predictors of recurrence, nuances such as the role of radical excision of dural attachment and postoperative ... ...

    Abstract Background: Meningiomas are the most frequent primary intracranial tumour. While histological grade and grade of excision are established predictors of recurrence, nuances such as the role of radical excision of dural attachment and postoperative radiotherapy in intermediate-risk groups remain unanswered.
    Method: This report presented data from 451 WHO Grade 1 and 248 WHO Grade 2 intracranial meningiomas operated between 2010 and 2015, analysing their clinical and radiological features and surgical details. Outcomes were assessed among 352 WHO Grade 1 and 208 WHO Grade 2 meningiomas, studying the effect of extent of resection and use of radiotherapy. Kaplan Meier analysis was used to determine differences in survival by extent of resection and use of postoperative radiotherapy in the treatment of WHO Grade 1 and 2 meningiomas.
    Results: The mean age of the cohort was 46.3 years, with a female predominance. On univariate analysis, gender, WHO grade, and Simpson grade were significant predictors of recurrence. On multivariate analysis, WHO grade and Simpsons grade remained significant predictors of recurrence. Recurrence was significantly associated with poor performance status and mortality. Postoperative radiation significantly improved progression-free survival among Grade 2 meningioma that underwent gross total resection (GTR), but not among WHO Grade 1 and 2 meningioma after subtotal resection (STR).
    Conclusion: WHO Grade and Simpson grade are independent predictors of recurrence among meningiomas. Irrespective of Grade, gross total resection must be effected when possible, and postoperative radiotherapy may be recommended in Grade 2 meningioma.
    Language English
    Publishing date 2024-04-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2024.04.082
    Database MEDical Literature Analysis and Retrieval System OnLINE

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