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  1. Article ; Online: Low CCR5 expression protects HIV-specific CD4+ T cells of elite controllers from viral entry

    Mathieu Claireaux / Rémy Robinot / Jérôme Kervevan / Mandar Patgaonkar / Isabelle Staropoli / Anne Brelot / Alexandre Nouël / Stacy Gellenoncourt / Xian Tang / Mélanie Héry / Stevenn Volant / Emeline Perthame / Véronique Avettand-Fenoël / Julian Buchrieser / Thomas Cokelaer / Christiane Bouchier / Laurence Ma / Faroudy Boufassa / Samia Hendou /
    Valentina Libri / Milena Hasan / David Zucman / Pierre de Truchis / Olivier Schwartz / Olivier Lambotte / Lisa A. Chakrabarti

    Nature Communications, Vol 13, Iss 1, Pp 1-

    2022  Volume 19

    Abstract: Here, Claireaux et al. show that people who naturally control HIV infection express lower levels of the viral co-receptor CCR5 in specific CD4+ T cells, and that this results from mutations or receptor internalization by CD4+ T cell-produced chemokines. ...

    Abstract Here, Claireaux et al. show that people who naturally control HIV infection express lower levels of the viral co-receptor CCR5 in specific CD4+ T cells, and that this results from mutations or receptor internalization by CD4+ T cell-produced chemokines.
    Keywords Science ; Q
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential

    Bjoern Meyer / Jeanne Chiaravalli / Stacy Gellenoncourt / Philip Brownridge / Dominic P. Bryne / Leonard A. Daly / Arturas Grauslys / Marius Walter / Fabrice Agou / Lisa A. Chakrabarti / Charles S. Craik / Claire E. Eyers / Patrick A. Eyers / Yann Gambin / Andrew R. Jones / Emma Sierecki / Eric Verdin / Marco Vignuzzi / Edward Emmott

    Nature Communications, Vol 12, Iss 1, Pp 1-

    2021  Volume 16

    Abstract: During SARS-CoV-2 replication, viral and cellular proteases play crucial roles and have been shown to be promising anti-viral targets. Here, Meyer et al. apply mass spectrometry to characterize the proteolytic cleavage profile of viral and cellular ... ...

    Abstract During SARS-CoV-2 replication, viral and cellular proteases play crucial roles and have been shown to be promising anti-viral targets. Here, Meyer et al. apply mass spectrometry to characterize the proteolytic cleavage profile of viral and cellular proteins in vitro.
    Keywords Science ; Q
    Language English
    Publishing date 2021-09-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: SARS-CoV-2 infection induces the dedifferentiation of multiciliated cells and impairs mucociliary clearance

    Rémy Robinot / Mathieu Hubert / Guilherme Dias de Melo / Françoise Lazarini / Timothée Bruel / Nikaïa Smith / Sylvain Levallois / Florence Larrous / Julien Fernandes / Stacy Gellenoncourt / Stéphane Rigaud / Olivier Gorgette / Catherine Thouvenot / Céline Trébeau / Adeline Mallet / Guillaume Duménil / Samy Gobaa / Raphaël Etournay / Pierre-Marie Lledo /
    Marc Lecuit / Hervé Bourhy / Darragh Duffy / Vincent Michel / Olivier Schwartz / Lisa A. Chakrabarti

    Nature Communications, Vol 12, Iss 1, Pp 1-

    2021  Volume 16

    Abstract: SARS-CoV-2 infection damages the airways. Here the authors show that SARS-CoV-2 infection induces the rapid loss of airway motile cilia, resulting in altered cilia clearance function. Cilia loss is preceded by reduced expression of the ciliogenesis ... ...

    Abstract SARS-CoV-2 infection damages the airways. Here the authors show that SARS-CoV-2 infection induces the rapid loss of airway motile cilia, resulting in altered cilia clearance function. Cilia loss is preceded by reduced expression of the ciliogenesis regulator Foxj1.
    Keywords Science ; Q
    Language English
    Publishing date 2021-07-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

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