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  1. AU="Stallings, Amy P"
  2. AU="Hardy, Mark A"
  3. AU="Kotrulja, Lena"
  4. AU="Meeremans, Marguerite"
  5. AU="Chen, Yanguang"
  6. AU="Sakizono, Kenji"
  7. AU="Romero-Daza, Nancy"
  8. AU="Jean-Pierre Thomé"
  9. AU=Narayanan Naveen
  10. AU=Azam Faizul
  11. AU="Özdog˘ru, Asil Ali"
  12. AU="Emami, Hajar"
  13. AU="Cimino, R."
  14. AU="Judith R. Stabel"
  15. AU="Takeuchi, Kazuto"
  16. AU="Mirzaei, Samira"
  17. AU="Carolina Salgado"
  18. AU="Mate, Sebastian"
  19. AU="Hou, Tian-Yang Liu"
  20. AU=Nino Gustavo
  21. AU="Lydon, Myra"
  22. AU="Jain, Nibha"
  23. AU="David A Schwartz"
  24. AU="Swart, Jonathan"
  25. AU="Karol, Agnieszka"
  26. AU="Reilly, Brittni"
  27. AU="Arfaatabar, Maryam"
  28. AU="Kumar Pandey, Anand"

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  1. Artikel: Case Report: Profound newborn leukopenia related to a novel RAC2 variant.

    Hall, Geoffrey / Donkó, Ágnes / Pratt, Cristina / Kim-Chang, Julie J / Martin, Paul L / Stallings, Amy P / Sleasman, John W / Holland, Steven M / Hsu, Amy P / Leto, Thomas L / Mousallem, Talal

    Frontiers in pediatrics

    2024  Band 12, Seite(n) 1365187

    Abstract: We report the case of a 1-week-old male born full-term, who had two inconclusive severe combined immunodeficiency (SCID) newborn screens and developed scalp cellulitis ... ...

    Abstract We report the case of a 1-week-old male born full-term, who had two inconclusive severe combined immunodeficiency (SCID) newborn screens and developed scalp cellulitis and
    Sprache Englisch
    Erscheinungsdatum 2024-03-07
    Erscheinungsland Switzerland
    Dokumenttyp Case Reports
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2024.1365187
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Improving the Documentation of Penicillin Allergy Labels Among Pediatric Inpatients.

    Hampton, Laura L / DeBoy, Jason T / Gunaratne, Aruni / Stallings, Amy P / Bell, Tara / Phillips, Michael A / Kamath, Sameer S / Sterrett, Emily C / Nazareth-Pidgeon, Kristina M

    Hospital pediatrics

    2023  Band 13, Heft 9, Seite(n) 811–821

    Abstract: Background and objectives: Penicillin allergy is the most common medication allergy, and the penicillin allergy label is commonly over-applied without adequate reaction history inquiry or documentation. Because penicillin allergy labels are often ... ...

    Abstract Background and objectives: Penicillin allergy is the most common medication allergy, and the penicillin allergy label is commonly over-applied without adequate reaction history inquiry or documentation. Because penicillin allergy labels are often applied in childhood and carried into adulthood, we sought to increase the completeness of reaction history documentation from 20% to 70% for pediatric hospital medicine patients and from 20% to 50% for all other pediatric inpatients within 12 months. As a secondary outcome, we also aimed to increase the proportion of delabeling unnecessary penicillin labels to 20% for all pediatric inpatients.
    Methods: To address our aims, our quality improvement initiative included education for pediatric faculty and staff, development and implementation of a clinical pathway for allergy risk stratification, and electronic health record optimizations. Statistical process control charts were used to track the impact of the interventions facilitated by an automated dashboard.
    Results: Within 12 months of interventions, the completeness of allergy labels improved from 20% to 64% among patients admitted to the pediatric hospital medicine service and improved from 20% to 45% for all other pediatric inpatients. The frequency of penicillin allergy delabeling remained unchanged; however, 98 patients were risk stratified and 34 received outpatient allergy referrals for further testing. The number of adverse drug reactions to penicillin, a balancing measure, did not change during the study period.
    Conclusions: We increased the completeness of penicillin allergy documentation using a standardized workflow facilitated by a multidisciplinary clinical pathway. With ongoing efforts, more penicillin delabeling in low-risk patients is anticipated.
    Mesh-Begriff(e) Humans ; Child ; Documentation ; Penicillins/adverse effects ; Anti-Bacterial Agents ; Drug Hypersensitivity ; Drug Labeling ; Quality Improvement
    Chemische Substanzen Penicillins ; Anti-Bacterial Agents
    Sprache Englisch
    Erscheinungsdatum 2023-08-10
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2154-1671
    ISSN (online) 2154-1671
    DOI 10.1542/hpeds.2022-006730
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Safety of Live Attenuated Influenza Vaccine in Children With Asthma.

    Sokolow, Andrew G / Stallings, Amy P / Kercsmar, Carolyn / Harrington, Theresa / Jimenez-Truque, Natalia / Zhu, Yuwei / Sokolow, Katherine / Moody, M Anthony / Schlaudecker, Elizabeth P / Walter, Emmanuel B / Staat, Mary Allen / Broder, Karen R / Creech, C Buddy

    Pediatrics

    2022  Band 149, Heft 4

    Abstract: Background and objectives: Asthma is considered a precaution for use of quadrivalent live attenuated influenza vaccine (LAIV4) in persons aged ≥5 years because of concerns for wheezing events. We evaluated the safety of LAIV4 in children with asthma, ... ...

    Abstract Background and objectives: Asthma is considered a precaution for use of quadrivalent live attenuated influenza vaccine (LAIV4) in persons aged ≥5 years because of concerns for wheezing events. We evaluated the safety of LAIV4 in children with asthma, comparing the proportion of children with asthma exacerbations after LAIV4 or quadrivalent inactivated influenza vaccine (IIV4).
    Methods: We enrolled 151 children with asthma, aged 5 to 17 years, during 2 influenza seasons. Participants were randomly assigned 1:1 to receive IIV4 or LAIV4 and monitored for asthma symptoms, exacerbations, changes in peak expiratory flow rate (PEFR), and changes in the asthma control test for 42 days after vaccination.
    Results: We included 142 participants in the per-protocol analysis. Within 42 days postvaccination, 18 of 142 (13%) experienced an asthma exacerbation: 8 of 74 (11%) in the LAIV4 group versus 10 of 68 (15%) in the IIV4 group (LAIV4-IIV4 = -0.0390 [90% confidence interval -0.1453 to 0.0674]), meeting the bounds for noninferiority. When adjusted for asthma severity, LAIV4 remained noninferior to IIV4. There were no significant differences in the frequency of asthma symptoms, change in PEFR, or childhood asthma control test/asthma control test scores in the 14 days postvaccination between LAIV4 and IIV4 recipients. Vaccine reactogenicity was similar between groups, although sore throat (P = .051) and myalgia (P <.001) were more common in the IIV4 group.
    Conclusions: LAIV4 was not associated with increased frequency of asthma exacerbations, an increase in asthma-related symptoms, or a decrease in PEFR compared with IIV4 among children aged 5 to 17 years with asthma.
    Mesh-Begriff(e) Adolescent ; Asthma ; Child ; Child, Preschool ; Humans ; Influenza Vaccines/adverse effects ; Influenza, Human/diagnosis ; Influenza, Human/prevention & control ; Vaccines, Attenuated/adverse effects ; Vaccines, Inactivated
    Chemische Substanzen Influenza Vaccines ; Vaccines, Attenuated ; Vaccines, Inactivated
    Sprache Englisch
    Erscheinungsdatum 2022-03-27
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Randomized Controlled Trial ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 207677-9
    ISSN 1098-4275 ; 0031-4005
    ISSN (online) 1098-4275
    ISSN 0031-4005
    DOI 10.1542/peds.2021-055432
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Asthma and neonatal airway colonization.

    Stallings, Amy P / Commins, Scott P / Platts-Mills, Thomas A E

    The New England journal of medicine

    2008  Band 358, Heft 4, Seite(n) 423–4; author reply 424–5

    Mesh-Begriff(e) Asthma/microbiology ; Bacterial Infections/complications ; Cesarean Section ; Humans ; Hypopharynx/microbiology ; Infant, Newborn ; Respiratory Sounds ; Respiratory Tract Infections/complications ; Risk Factors ; Siblings
    Sprache Englisch
    Erscheinungsdatum 2008-01-24
    Erscheinungsland United States
    Dokumenttyp Comment ; Letter
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.34: Hefte anzeigen Standort:
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  5. Artikel ; Online: Galactose-α-1,3-galactose and delayed anaphylaxis, angioedema, and urticaria in children.

    Kennedy, Joshua L / Stallings, Amy P / Platts-Mills, Thomas A E / Oliveira, Walter M / Workman, Lisa / James, Haley R / Tripathi, Anubha / Lane, Charles J / Matos, Luis / Heymann, Peter W / Commins, Scott P

    Pediatrics

    2013  Band 131, Heft 5, Seite(n) e1545–52

    Abstract: Background and objective: Despite a thorough history and comprehensive testing, many children who present with recurrent symptoms consistent with allergic reactions elude diagnosis. Recent research has identified a novel cause for "idiopathic" allergic ... ...

    Abstract Background and objective: Despite a thorough history and comprehensive testing, many children who present with recurrent symptoms consistent with allergic reactions elude diagnosis. Recent research has identified a novel cause for "idiopathic" allergic reactions; immunoglobulin E (IgE) antibody specific for the carbohydrate galactose-α-1,3-galactose (α-Gal) has been associated with delayed urticaria and anaphylaxis that occurs 3 to 6 hours after eating beef, pork, or lamb. We sought to determine whether IgE antibody to α-Gal was present in sera of pediatric patients who reported idiopathic anaphylaxis or urticaria.
    Methods: Patients aged 4 to 17 were enrolled in an institutional review board-approved protocol at the University of Virginia and private practice allergy offices in Lynchburg, VA. Sera was obtained and analyzed by ImmunoCAP for total IgE and specific IgE to α-Gal, beef, pork, cat epithelium and dander, Fel d 1, dog dander, and milk.
    Results: Forty-five pediatric patients were identified who had both clinical histories supporting delayed anaphylaxis or urticaria to mammalian meat and IgE antibody specific for α-Gal. In addition, most of these cases had a history of tick bites within the past year, which itched and persisted.
    Conclusions: A novel form of anaphylaxis and urticaria that occurs 3 to 6 hours after eating mammalian meat is not uncommon among children in our area. Identification of these cases may not be straightforward and diagnosis is best confirmed by specific testing, which should certainly be considered for children living in the area where the Lone Star tick is common.
    Mesh-Begriff(e) Adolescent ; Age Distribution ; Allergens/immunology ; Angioedema/epidemiology ; Angioedema/immunology ; Animals ; Biomarkers/blood ; Cats ; Cattle ; Child ; Child, Preschool ; Cohort Studies ; Disaccharides/immunology ; Disaccharides/metabolism ; Dogs ; Female ; Food Hypersensitivity/epidemiology ; Food Hypersensitivity/etiology ; Food Hypersensitivity/immunology ; Humans ; Hypersensitivity, Delayed/epidemiology ; Hypersensitivity, Delayed/immunology ; Immunoglobulin E/immunology ; Incidence ; Male ; Meat/adverse effects ; Prognosis ; Risk Assessment ; Sex Distribution ; Skin Tests ; Statistics, Nonparametric ; Swine ; Time Factors ; Urticaria/epidemiology ; Urticaria/immunology ; Virginia
    Chemische Substanzen Allergens ; Biomarkers ; Disaccharides ; galactosyl-(1-3)galactose (13168-24-6) ; Immunoglobulin E (37341-29-0)
    Sprache Englisch
    Erscheinungsdatum 2013-04-08
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 207677-9
    ISSN 1098-4275 ; 0031-4005
    ISSN (online) 1098-4275
    ISSN 0031-4005
    DOI 10.1542/peds.2012-2585
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Um IV Zs.131: Hefte anzeigen Standort:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
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