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  1. Article ; Online: Coherence mapping to identify the intermediates of multi-channel dissociative ionization.

    Stamm, Jacob / Kwon, Sung / Sandhu, Shawn / Sandhu, Jesse / Levine, Benjamin G / Dantus, Marcos

    Communications chemistry

    2024  Volume 7, Issue 1, Page(s) 103

    Abstract: Identifying the short-lived intermediates and reaction mechanisms of multi-channel radical cation fragmentation processes remains a current and important challenge to understanding and predicting mass spectra. We find that coherent oscillations in the ... ...

    Abstract Identifying the short-lived intermediates and reaction mechanisms of multi-channel radical cation fragmentation processes remains a current and important challenge to understanding and predicting mass spectra. We find that coherent oscillations in the femtosecond time-dependent yields of several product ions following ultrafast strong-field ionization represent spectroscopic signatures that elucidate their mechanism of formation and identify the intermediate(s) they originate from. Experiments on endo-dicyclopentadiene show that vibrational frequencies from various intermediates are mapped onto their resulting products. Aided by ab initio methods, we identify the vibrational modes of both the cleaved and intact molecular ion intermediates. These results confirm stepwise and concerted fragmentation pathways of the dicyclopentadiene ion. This study highlights the power of tracking the femtosecond dynamics of all product ions simultaneously and sheds further light onto one of the fundamental reaction mechanisms in mass spectrometry, the retro-Diels Alder reaction.
    Language English
    Publishing date 2024-05-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2929562-2
    ISSN 2399-3669 ; 2399-3669
    ISSN (online) 2399-3669
    ISSN 2399-3669
    DOI 10.1038/s42004-024-01176-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Quantitative Identification of Nonpolar Perfluoroalkyl Substances by Mass Spectrometry.

    Stamm, Jacob / DeJesus, Lindsey / Jones, A Daniel / Dantus, Marcos

    The journal of physical chemistry. A

    2022  Volume 126, Issue 47, Page(s) 8851–8858

    Abstract: Identifying and quantifying mixtures of compounds with very similar fragmentation patterns in their mass spectra presents a unique and challenging problem. In particular, the mass spectra of most per- and poly-fluoroalkyl substances (PFAS) lack a ... ...

    Abstract Identifying and quantifying mixtures of compounds with very similar fragmentation patterns in their mass spectra presents a unique and challenging problem. In particular, the mass spectra of most per- and poly-fluoroalkyl substances (PFAS) lack a molecular ion. This complicates their identification, especially when using the absence of chromatographic separation. Here, we focus on linear, nonpolar, short-chain PFAS, which have received less attention than amphipathic PFAS despite their longer environmental lifetimes and greater global warming potentials. We identify and quantify
    MeSH term(s) Fluorocarbons/analysis ; Mass Spectrometry/methods ; Electrons ; Cations
    Chemical Substances Fluorocarbons ; Cations
    Language English
    Publishing date 2022-11-16
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5215
    ISSN (online) 1520-5215
    DOI 10.1021/acs.jpca.2c05373
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Management of pediatric ureterolithiasis in the emergency room: A single institution review and new management pathway.

    Nelson, Ryan / Stamm, John / Timmons, Zebulon / Grimsby, Gwen M

    Journal of pediatric urology

    2022  Volume 19, Issue 2, Page(s) 177.e1–177.e6

    Abstract: Introduction/background: Urolithiasis is an increasingly common condition seen in children with an annual incidence of 2-3% in children under 18, and up to 10% in adolescents. Treatment of stones varies including observation, IV hydration, pain ... ...

    Abstract Introduction/background: Urolithiasis is an increasingly common condition seen in children with an annual incidence of 2-3% in children under 18, and up to 10% in adolescents. Treatment of stones varies including observation, IV hydration, pain management, medical expulsive therapy (MET), or surgery. Though well-studied and often used in adults, MET (alpha-adrenergic antagonists to facilitate passage of ureteral stones), is not routinely prescribed in pediatric patients.
    Objective: The goals of this study were to review a quaternary children's hospital's emergency room frequency of MET utilization for ureterolithiasis as well as evaluate the clinical outcomes of children who were prescribed MET compared to those treated with pain control alone.
    Study design: A retrospective review was performed of children 2 months to 18 years with ureterolithiasis who presented to a quaternary children's hospital ED from 2011 to 2017. The primary outcome was the frequency of MET prescribed. Secondary outcomes included the following comparisons in patients who received MET and analgesics with those who received analgesics alone: hospital admission rate, length of hospitalization, emergency room re-presentation rate, surgical intervention, spontaneous stone passage, urology consultation, how the urology consult affected MET utilization, referral to outpatient urology and nephrology clinics, and CT utilization in the ED. Comparisons were performed utilizing Fischer's exact and t-tests.
    Results: 139 patients were included with a mean age of 14 years (SD 4.14), 42% male. There was no difference between age, gender, stone size, return to the ED, serum creatinine, or length of hospitalization (if admitted) between patients who were and were not placed on MET. The rate of stone passage was significantly higher for those placed on MET (45%) versus not (20%) (p = 0.0022). Urology was consulted for 93% of the cases where children were prescribed MET, compared with only 52% of cases where MET was not prescribed (p = <0.0001).
    Discussion: In our experience MET was significantly underutilized in patients where urology was not involved. This is similar to a study by Itano et al. which found urology consultation in the ED significantly increased use of tamsulosin for ureterolithiasis in adults. Children with ureterolithiasis placed on MET had a significantly higher rate of stone passage compared to children managed by pain control alone.
    Conclusion: Given the benefits of MET to increase the rate of spontaneous stone passage it may be considered first line therapy for treatment of children with ureterolithiasis.
    MeSH term(s) Adult ; Adolescent ; Humans ; Male ; Child ; Female ; Treatment Outcome ; Ureteral Calculi/complications ; Emergency Service, Hospital ; Analgesics/therapeutic use ; Pain/complications ; Pain/drug therapy
    Chemical Substances Analgesics
    Language English
    Publishing date 2022-11-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2237683-5
    ISSN 1873-4898 ; 1477-5131
    ISSN (online) 1873-4898
    ISSN 1477-5131
    DOI 10.1016/j.jpurol.2022.11.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Integrierte Versorgung in der Kardiologie: Haben alle ihre Chancen genutzt?

    Stamm, J

    Clinical research in cardiology : official journal of the German Cardiac Society

    2006  Volume 95 Suppl 2, Page(s) II16–18

    Abstract: From the view of one of the largest public health insurance companies, in this paper it is outlined that Integrated Health Care provides opportunities to influence the largely regional structures of health care supply. This insurance company has ... ...

    Title translation Integrated Health Care in cardiology: have all players used their opportunities?.
    Abstract From the view of one of the largest public health insurance companies, in this paper it is outlined that Integrated Health Care provides opportunities to influence the largely regional structures of health care supply. This insurance company has specialized in contracts for Integrated Health Care in cardiology in order to achieve sustainable solutions for all providers of invasive and interventional cardiology that are economically reasonable. But first of all, only evidence-based medical procedures and interventions based on clinical pathways are eligible for the contracts of this company. In outlining this, it becomes evident that by far not all German public health insurance companies have yet used their opportunity.
    MeSH term(s) Cardiology/economics ; Cardiology/standards ; Cardiology/trends ; Delivery of Health Care, Integrated/economics ; Delivery of Health Care, Integrated/organization & administration ; Delivery of Health Care, Integrated/standards ; Family Practice ; Germany ; Humans ; Insurance, Health/economics ; Insurance, Health/trends ; Insurance, Major Medical/economics ; Insurance, Major Medical/trends ; Marketing of Health Services/economics ; National Health Programs/economics ; Quality of Health Care
    Language German
    Publishing date 2006-01
    Publishing country Germany
    Document type English Abstract ; Journal Article
    ZDB-ID 2213295-8
    ISSN 1861-0692 ; 1861-0684
    ISSN (online) 1861-0692
    ISSN 1861-0684
    DOI 10.1007/s00392-006-1205-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Moderne Versorgungskonzepte--Was wurde erreicht bei der Integrierten Versorgung?

    Stamm, J

    Zeitschrift fur Kardiologie

    2005  Volume 94 Suppl 4, Page(s) IV/4–6

    Abstract: The legal framework for Integrated Health Care since 2004 offers many opportunities for health professionals and insurers in the competition for "high quality care". Germany's largest statutory health insurance fund, BARMER, has already developed around ... ...

    Title translation Implementing integrated health care--current state and progress.
    Abstract The legal framework for Integrated Health Care since 2004 offers many opportunities for health professionals and insurers in the competition for "high quality care". Germany's largest statutory health insurance fund, BARMER, has already developed around 100 Integrated Health Care Projects for a wide range of conditions. One important issue is the relationship to disease management programs. Our program "integrated cardiological care" combines both DMP and integrated health care and thus already shows good results with respect to patient acceptance as well as savings trough the changing patterns in interventional cardiology.
    MeSH term(s) Cardiology/economics ; Cardiology/organization & administration ; Cost Savings/trends ; Delivery of Health Care, Integrated/economics ; Delivery of Health Care, Integrated/organization & administration ; Disease Management ; Economic Competition/economics ; Economic Competition/organization & administration ; Forecasting ; Germany ; Health Plan Implementation/economics ; Health Plan Implementation/organization & administration ; Humans ; National Health Programs/economics ; National Health Programs/organization & administration ; Physician-Patient Relations ; Quality Assurance, Health Care/economics ; Quality Assurance, Health Care/organization & administration
    Language German
    Publishing date 2005
    Publishing country Germany
    Document type English Abstract ; Journal Article
    ZDB-ID 124481-4
    ISSN 1435-1285 ; 0300-5860
    ISSN (online) 1435-1285
    ISSN 0300-5860
    DOI 10.1007/s00392-005-1402-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Milliradian precision ultrafast pulse control for spectral phase metrology.

    Stamm, Jacob / Benel, Jorge / Escoto, Esmerando / Steinmeyer, Günter / Dantus, Marcos

    Optics express

    2021  Volume 29, Issue 10, Page(s) 14314–14325

    Abstract: A pulse-shaper-based method for spectral phase measurement and compression with milliradian precision is proposed and tested experimentally. Measurements of chirp and third-order dispersion are performed and compared to theoretical predictions. The ... ...

    Abstract A pulse-shaper-based method for spectral phase measurement and compression with milliradian precision is proposed and tested experimentally. Measurements of chirp and third-order dispersion are performed and compared to theoretical predictions. The single-digit milliradian accuracy is benchmarked by a group velocity dispersion measurement of fused silica.
    Language English
    Publishing date 2021-02-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.422739
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: What is the Mechanism of H

    Kwon, Sung / Sandhu, Shawn / Shaik, Moaid / Stamm, Jacob / Sandhu, Jesse / Das, Rituparna / Hetherington, Caitlin V / Levine, Benjamin G / Dantus, Marcos

    The journal of physical chemistry. A

    2023  Volume 127, Issue 41, Page(s) 8633–8638

    Abstract: We examine the possibility that three hydrogen atoms in one plane of the cyclopropane dication come together in a concerted "ring-closing" mechanism to form ... ...

    Abstract We examine the possibility that three hydrogen atoms in one plane of the cyclopropane dication come together in a concerted "ring-closing" mechanism to form H
    Language English
    Publishing date 2023-10-09
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5215
    ISSN (online) 1520-5215
    DOI 10.1021/acs.jpca.3c05442
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Integrierte Versorgung in der Kardiologie: Haben alle ihre Chancen genutzt?

    Stamm, J.

    Clinical research in cardiology

    2006  Volume 95, Issue Suppl.2, Page(s) 16

    Language German
    Document type Article
    ZDB-ID 2213295-8
    ISSN 1861-0684
    Database Current Contents Medicine

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  9. Article ; Online: "Jedes Jahr mehr ist ein Jahr weniger"

    Stamm, Judith

    Zenit ; - ; 2011 ; 4 ; 33

    Gedanken von Ex-Nationalpräsidentin Judith Stamm

    2011  

    Publishing date 2011-12-01
    Publisher Pro Senectute Kanton Luzern
    Publishing country ch
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Development of an artificial synovial fluid useful for studying

    Stamm, Johanna / Weißelberg, Samira / Both, Anna / Failla, Antonio Virgilio / Nordholt, Gerhard / Büttner, Henning / Linder, Stefan / Aepfelbacher, Martin / Rohde, Holger

    Frontiers in cellular and infection microbiology

    2022  Volume 12, Page(s) 948151

    Abstract: Staphylococcus ... ...

    Abstract Staphylococcus epidermidis
    MeSH term(s) Adhesins, Bacterial/metabolism ; Biofilms ; Humans ; Polysaccharides, Bacterial/metabolism ; Staphylococcus epidermidis/genetics ; Synovial Fluid/metabolism
    Chemical Substances Adhesins, Bacterial ; Polysaccharides, Bacterial
    Language English
    Publishing date 2022-07-29
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2022.948151
    Database MEDical Literature Analysis and Retrieval System OnLINE

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