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Book ; Online: Data Mining in MRO : Centre for Applied Research Technology

Pelt, Maurice / Apostolidis, Asteris / de Boer, Robert J. / Borst, Maaik / Broodbakker, Jonno / Jansen, Ruud / Helwani, Lorance / Patron, Roberto / Stamoulis, Konstantinos

2019

Keywords	Computing & information technology ; data mining ; U
Size	1 electronic resource (53 pages)
Publisher	Amsterdam University of Applied Sciences
Document type	Book ; Online
Note	English ; Open Access
HBZ-ID	HT021030451
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article: Composites in Aerospace and Mechanical Engineering.

Georgantzinos, Stelios K / Giannopoulos, Georgios I / Stamoulis, Konstantinos / Markolefas, Stylianos

Materials (Basel, Switzerland)

2023 Volume 16, Issue 22

Abstract: An important step towards improving performance while reducing weight and maintenance needs is the integration of composite materials into mechanical and aerospace engineering. This subject explores the many aspects of composite application, from basic ... ...

Abstract	An important step towards improving performance while reducing weight and maintenance needs is the integration of composite materials into mechanical and aerospace engineering. This subject explores the many aspects of composite application, from basic material characterization to state-of-the-art advances in manufacturing and design processes. The major goal is to present the most recent developments in composite science and technology while highlighting their critical significance in the industrial sector-most notably in the wind energy, automotive, aerospace, and marine domains. The foundation of this investigation is material characterization, which offers insights into the mechanical, chemical, and physical characteristics that determine composite performance. The papers in this collection discuss the difficulties of gaining an in-depth understanding of composites, which is necessary to maximize their overall performance and design. The collection of articles within this topic addresses the challenges of achieving a profound understanding of composites, which is essential for optimizing design and overall functionality. This includes the application of complicated material modeling together with cutting-edge simulation tools that integrate multiscale methods and multiphysics, the creation of novel characterization techniques, and the integration of nanotechnology and additive manufacturing. This topic offers a detailed overview of the current state and future directions of composite research, covering experimental studies, theoretical evaluations, and numerical simulations. This subject provides a platform for interdisciplinary cooperation and creativity in everything from the processing and testing of innovative composite structures to the inspection and repair procedures. In order to support the development of more effective, durable, and sustainable materials for the mechanical and aerospace engineering industries, we seek to promote a greater understanding of composites.
Language	English
Publishing date	2023-11-19
Publishing country	Switzerland
Document type	Editorial
ZDB-ID	2487261-1
ISSN	1996-1944
ISSN	1996-1944
DOI	10.3390/ma16227230
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Perioperative management of antithrombotics in elective intracranial procedures: systematic review, critical appraisal.

Ntalouka, Maria P / Brotis, Alexandros / Karagianni, Maria D / Arvaniti, Christina / Mermiri, Maria / Solou, Maria / Stamoulis, Konstantinos / Bareka, Metaxia / Fountas, Konstantinos N / Arnaoutoglou, Eleni M

Acta neurochirurgica

2024 Volume 166, Issue 1, Page(s) 97

Abstract: Purpose: Perioperative management of patients medicated with antithrombotics requiring elective intracranial procedures is challenging. We ought to (1) identify the clinical practice guidelines (CPGs) and recommendations (CPRs) on perioperative ... ...

Abstract	Purpose: Perioperative management of patients medicated with antithrombotics requiring elective intracranial procedures is challenging. We ought to (1) identify the clinical practice guidelines (CPGs) and recommendations (CPRs) on perioperative management of antithrombotic agents in elective intracranial surgery and (2) assess their methodological quality and reporting clarity. Methods: The study was conducted following the 2020 PRISMA guidelines for a systematic review and has been registered (PROSPERO, CRD42023415710). An electronic search was conducted using PubMed, Scopus, and Google Scholar. The search terms used were "adults," "antiplatelets," "anticoagulants," "guidelines," "recommendations," "english language," "cranial surgery," "brain surgery," "risk of bleeding," "risk of coagulation," and "perioperative management" in all possible combinations. The search period extended from 1964 to April 2023 and was limited to literature published in the English language. The eligible studies were evaluated by three blinded raters, by employing the Appraisal of Guidelines for Research & Evaluation II (AGREE-II) analysis tool. Results: A total of 14 sets of guidelines were evaluated. Two guidelines from the European Society of Anaesthesiology and one from the American College of Chest Physicians found to have the highest methodological quality and reporting clarity according to the AGREE-II tool. The interrater agreement was good with a mean Cohens Kappa of 0.70 (range, 46.5-94.4%) in the current analysis. Conclusion: The perioperative management of antithrombotics in intracranial procedures may be challenging, complex, and demanding. Due to the lack of high quality data, uncertainty remains regarding the optimal practices to balance the risk of thromboembolism against that of bleeding.
MeSH term(s)	Adult ; Humans ; Fibrinolytic Agents/therapeutic use ; Hemorrhage ; Anticoagulants/therapeutic use
Chemical Substances	Fibrinolytic Agents ; Anticoagulants
Language	English
Publishing date	2024-02-21
Publishing country	Austria
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	80010-7
ISSN	0942-0940 ; 0001-6268
ISSN (online)	0942-0940
ISSN	0001-6268
DOI	10.1007/s00701-024-05990-7
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Article: Deciphering the Relationship Between Free and Vesicular Hemoglobin in Stored Red Blood Cell Units.

Tzounakas, Vassilis L / Anastasiadi, Alkmini T / Lekka, Marilena E / Papageorgiou, Effie G / Stamoulis, Konstantinos / Papassideri, Issidora S / Kriebardis, Anastasios G / Antonelou, Marianna H

Frontiers in physiology

2022 Volume 13, Page(s) 840995

Abstract: Red blood cells (RBCs) release hemoglobin (Hb)-containing extracellular vesicles (EVs) throughout their lifespan in the circulation, and especially during senescence, by spleen-facilitated vesiculation of their membrane. ... ...

Abstract	Red blood cells (RBCs) release hemoglobin (Hb)-containing extracellular vesicles (EVs) throughout their lifespan in the circulation, and especially during senescence, by spleen-facilitated vesiculation of their membrane. During
Language	English
Publishing date	2022-02-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564217-0
ISSN	1664-042X
ISSN	1664-042X
DOI	10.3389/fphys.2022.840995
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Article ; Online: Effect of prolonged storage on quality characteristics of recovered plasma: Is there an expiration date?

Politou, Marianna / Kontoteza, Ifigeneia Vasiliki / Pouliakis, Abraham / Dryllis, Georgios / Fortsa, Panagiota / Valsami, Serena / Stamoulis, Konstantinos

Transfusion

2022 Volume 62, Issue 11, Page(s) 2188–2193

Abstract: Background: Although there are guidelines on industrial manufacture of plasma-derived medicinal products, there are no clear recommendations about plasma intended for fractionation, as there is no expiry time and the effect of prolonged storage on the ... ...

Abstract	Background: Although there are guidelines on industrial manufacture of plasma-derived medicinal products, there are no clear recommendations about plasma intended for fractionation, as there is no expiry time and the effect of prolonged storage on the activity of coagulation factors is unknown. Study and design methods: A total of 237 units of plasma stored at -30°C in the National Blood Transfusion Centre for 1 year (62 units), 5 years (75 units), and 10 years (100 units) were studied. The effect of storage time was investigated by determining the activity of clotting factors FII, FV, FVII, FVIII, FIX, FX, FXI, FXII, FXIII using coagulometric methods and antithrombin III and fibrinogen with chromogenic assays, using System BCS Results: Albumin, AT III, fibrinogen, FIX, FXI, FXII, and FXIII remain rather stable even after 10 years of storage. Levels of FII, FV, FVII, FVIII, and FX decreased after 5 years of storage. Discussion: Our study is in agreement with all the previous studies and concludes that there is a putative usability of recovered plasma and some of its coagulation factors after many years of storage at the recommended temperature.
MeSH term(s)	Humans ; Blood Preservation/methods ; Time Factors ; Blood Coagulation Factors ; Fibrinogen ; Albumins
Chemical Substances	Blood Coagulation Factors ; Fibrinogen (9001-32-5) ; Albumins
Language	English
Publishing date	2022-09-19
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	208417-x
ISSN	1537-2995 ; 0041-1132
ISSN (online)	1537-2995
ISSN	0041-1132
DOI	10.1111/trf.17115
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Article: A COVID-19 outbreak among migrants in a hosting facility in Greece, April 2020.

Mellou, Kassiani / Gkolfinopoulou, Kassiani / Andreopoulou, Anastasia / Tsekou, Aikaterini / Papadima, Kalliopi / Stamoulis, Konstantinos / Kossyvakis, Athanasios / Mentis, Andreas / Maltezou, Helena C

Journal of infection prevention

2022 Volume 23, Issue 5, Page(s) 235–238

Abstract: In April 2020, a coronavirus disease 2019 outbreak was identified among migrants/refugees in Greece. Overall, 155 of 450 hosted migrants and two of 46 employees were infected (attack rates: 34.4% and 4.3%, respectively). The mean age of infected migrants ...

Abstract	In April 2020, a coronavirus disease 2019 outbreak was identified among migrants/refugees in Greece. Overall, 155 of 450 hosted migrants and two of 46 employees were infected (attack rates: 34.4% and 4.3%, respectively). The mean age of infected migrants was 24.9 years (3 days-68 years). In addition, 177 community contacts were tested negative. Cases were cohorted in separate rooms from people tested negative. Surfaces were cleaned and disinfected daily. The implementation of measures for the containment of the outbreak was challenging due to language barriers and lack of space for cohorting. At that time, there was no official recommendation to the general population regarding the use of masks or other personal protective equipment. Extensive testing of vulnerable populations and building trust in order to report symptoms and comply with the recommendations are essential.
Language	English
Publishing date	2022-05-04
Publishing country	England
Document type	Journal Article
ZDB-ID	2595000-9
ISSN	1757-1782 ; 1757-1774
ISSN (online)	1757-1782
ISSN	1757-1774
DOI	10.1177/17571774221092568
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Article: Economic crisis in Greece: The invisible enemy of blood donation or not?

Fortis, Sotirios P / Kriebardis, Anastasios G / Georgatzakou, Hara T / Lyrakos, George / Alexiou, Panagiotis / Antoniou, Charalampos / Papadopoulos, George / Stamoulis, Konstantinos E / Valsami, Serena

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis

2022 Volume 61, Issue 6, Page(s) 103467

Abstract: Introduction: Volunteering presupposes having free time and refers to the provision of services without the motivation of material reward, for the benefit of society. In this study, we aimed to provide insight into the impact of economic crisis on blood ...

Abstract	Introduction: Volunteering presupposes having free time and refers to the provision of services without the motivation of material reward, for the benefit of society. In this study, we aimed to provide insight into the impact of economic crisis on blood donors and their motivation to donate blood during that period. Study design and methods: We asked blood donors about their blood donation activity and motivation to donate using a standardized, anonymous questionnaire (n = 3000). Descriptive analysis was performed for the consideration of donor turnout during this economic period. The results were analyzed using the χ Results: Regarding gender, 68.2% were males, while 31.8% were females. Most blood donors donated voluntarily (75.8%) and only 24.2% were replacement or family blood donors. The economic crisis has affected the inhabitants of Athens more than the inhabitants of the province (χ Conclusion: Although the economic crisis has affected the lives of blood donors, it does not seem to affect the frequency of blood donation. We suggest that blood collection services should consider specialist campaigns that focus on the altruistic motivation of donors during an economic crisis.
MeSH term(s)	Male ; Female ; Humans ; Blood Donors ; Greece ; Economic Recession ; Quality of Life ; Altruism ; Motivation ; Surveys and Questionnaires
Language	English
Publishing date	2022-05-21
Publishing country	England
Document type	Journal Article
ZDB-ID	2046795-3
ISSN	1878-1683 ; 1473-0502
ISSN (online)	1878-1683
ISSN	1473-0502
DOI	10.1016/j.transci.2022.103467
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Article ; Online: The time-course linkage between hemolysis, redox, and metabolic parameters during red blood cell storage with or without uric acid and ascorbic acid supplementation.

Anastasiadi, Alkmini T / Stamoulis, Konstantinos / Papageorgiou, Effie G / Lelli, Veronica / Rinalducci, Sara / Papassideri, Issidora S / Kriebardis, Anastasios G / Antonelou, Marianna H / Tzounakas, Vassilis L

Frontiers in aging

2023 Volume 4, Page(s) 1161565

Abstract: Oxidative phenomena are considered to lie at the root of the accelerated senescence observed in red blood cells (RBCs) stored under standard blood bank conditions. It was recently shown that the addition of uric (UA) and/or ascorbic acid (AA) to the ... ...

Abstract	Oxidative phenomena are considered to lie at the root of the accelerated senescence observed in red blood cells (RBCs) stored under standard blood bank conditions. It was recently shown that the addition of uric (UA) and/or ascorbic acid (AA) to the preservative medium beneficially impacts the storability features of RBCs related to the handling of pro-oxidant triggers. This study constitutes the next step, aiming to examine the links between hemolysis, redox, and metabolic parameters in control and supplemented RBC units of different storage times. For this purpose, a paired correlation analysis of physiological and metabolism parameters was performed between early, middle, and late storage in each subgroup. Strong and repeated correlations were observed throughout storage in most hemolysis parameters, as well as in reactive oxygen species (ROS) and lipid peroxidation, suggesting that these features constitute donor-signatures, unaffected by the diverse storage solutions. Moreover, during storage, a general "dialogue" was observed between parameters of the same category (e.g., cell fragilities and hemolysis or lipid peroxidation and ROS), highlighting their interdependence. In all groups, extracellular antioxidant capacity, proteasomal activity, and glutathione precursors of preceding time points anticorrelated with oxidative stress lesions of upcoming ones. In the case of supplemented units, factors responsible for glutathione synthesis varied proportionally to the levels of glutathione itself. The current findings support that UA and AA addition reroutes the metabolism to induce glutathione production, and additionally provide mechanistic insight and footing to examine novel storage optimization strategies.
Language	English
Publishing date	2023-03-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	3076785-4
ISSN	2673-6217 ; 2673-6217
ISSN (online)	2673-6217
ISSN	2673-6217
DOI	10.3389/fragi.2023.1161565
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Article: Predictors of 30-Day Postoperative Outcome after Elective Endovascular Abdominal Aortic Aneurysm Repair: A Tertiary Referral Center Experience.

Ntalouka, Maria P / Nana, Petroula / Brotis, Alexandros / Chatzis, Athanasios / Mermiri, Maria / Stamoulis, Konstantinos / Bareka, Metaxia / Giannoukas, Athanasios / Matsagkas, Miltiadis / Arnaoutoglou, Eleni

Journal of clinical medicine

2023 Volume 12, Issue 18

Abstract: Background: We evaluated the 30-day postoperative outcome after elective endovascular aneurysm repair (EVAR) and the possible predictors for the 30-day postoperative outcome.: Materials: Demographics, medical history, laboratory values, intensive ... ...

Abstract	Background: We evaluated the 30-day postoperative outcome after elective endovascular aneurysm repair (EVAR) and the possible predictors for the 30-day postoperative outcome. Materials: Demographics, medical history, laboratory values, intensive care unit (ICU) admission and 30-day complications classified as major (major adverse cardiovascular events (MACEs), acute kidney injury (AKI) and death of any cause) and minor (postimplantation syndrome (PIS), postoperative delirium (POD), urinary tract infection (UTI) and technical graft failure) were documented (March 2016 to February 2019). Results: We included 322 patients. The majority were managed under general anesthesia (83%) with femoral cutdown (98.1%). Overall, 121 (37.5%) complications, mostly minor ( Conclusions: Our study showed that the 30-day morbidity after EVAR exceeded 35%. However, the majority of complications were minor, and the associated mortality was low. Aneurysm diameter and past smoking were independent predictors for postoperative outcome.
Language	English
Publishing date	2023-09-16
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12186004
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Article: Association of Neutrophil-Lymphocyte and Platelet-Lymphocyte Ratio with Adverse Events in Endovascular Repair for Abdominal Aortic Aneurysm.

Ntalouka, Maria P / Nana, Petroula / Kouvelos, George N / Stamoulis, Konstantinos / Spanos, Konstantinos / Giannoukas, Athanasios / Matsagkas, Miltiadis / Arnaoutoglou, Eleni

Journal of clinical medicine

2021 Volume 10, Issue 5

Abstract: The association of chronic inflammatory markers with the clinical outcome after endovascular aneurysm repair (EVAR) for abdominal aortic aneurysm (AAA) was investigated. We included 230 patients, treated electively with EVAR. The values of neutrophil- ... ...

Abstract	The association of chronic inflammatory markers with the clinical outcome after endovascular aneurysm repair (EVAR) for abdominal aortic aneurysm (AAA) was investigated. We included 230 patients, treated electively with EVAR. The values of neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) were measured pre- and postoperatively. Any major adverse cardiovascular event (MACE) and acute kidney injury (AKI) were recorded. Adverse events occurred in 12 patients (5.2%). Seven patients suffered from MACE and five from AKI. Median NLR and PLR values were significantly increased after the procedure (NLR: from 3.34 to 8.64,
Language	English
Publishing date	2021-03-05
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm10051083
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