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  1. Book ; Online: Chapter Computation of Scintillation Indices for the Galileo E1 Signals Using a Software Receiver

    Vučković, Marko / Stanič, S.

    2014  

    Keywords Earth sciences ; Earth sciences, geography, environment, planning
    Size 1 Online-Ressource
    Publisher InTechOpen
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021047804
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Letter to the Editor: Ervin G. Erdös, MD (1922-2019): a holocaust survivor and eminent cardiovascular scientist.

    Stanic, Sinisa

    American journal of physiology. Heart and circulatory physiology

    2020  Volume 318, Issue 5, Page(s) H1049–H1050

    MeSH term(s) Angiotensins/metabolism ; Cardiology/history ; History, 20th Century ; History, 21st Century ; Hypertension/metabolism ; Hypertension/physiopathology ; Physiology/history
    Chemical Substances Angiotensins
    Language English
    Publishing date 2020-04-08
    Publishing country United States
    Document type Biography ; Historical Article ; Letter ; Portrait
    ZDB-ID 603838-4
    ISSN 1522-1539 ; 0363-6135
    ISSN (online) 1522-1539
    ISSN 0363-6135
    DOI 10.1152/ajpheart.00100.2020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Saltwater Intrusion Into a Confined Island Aquifer Driven by Erosion, Changing Recharge, Sea‐Level Rise, and Coastal Flooding

    Stanic, S. / LeRoux, N. K. / Paldor, A. / Mohammed, A. A. / Michael, H. A. / Kurylyk, B. L.

    Water Resources Research. 2024 Jan., v. 60, no. 1 p.e2023WR036394-

    2024  

    Abstract: Aquifers on small islands are at risk of salinization due to low elevations and limited adaptive capacity, and present risks will be exacerbated by climate change. Most studies addressing small‐island saltwater intrusion (SWI) have focused on homogeneous ...

    Abstract Aquifers on small islands are at risk of salinization due to low elevations and limited adaptive capacity, and present risks will be exacerbated by climate change. Most studies addressing small‐island saltwater intrusion (SWI) have focused on homogeneous sandy islands and one or two hydraulic disturbances. We herein investigate SWI dynamics in a layered, confined island aquifer in response to multiple environmental perturbations related to climate change, with two considered in tandem. Our field and modeling work is based on an island aquifer that provides the drinking water supply for an Indigenous community in Atlantic Canada. Observation well data and electrical resistivity profiles were used to calibrate a numerical model (HydroGeoSphere) of coupled groundwater flow and salt transport. The calibrated model was used to simulate the impacts of climate change including sea‐level rise (SLR), storm surge overtopping, changing aquifer recharge, and erosion. Simulated aquifer conditions were resilient to surges because the confining layer prevented deeper saltwater leaching. However, reduced recharge and erosion resulted in saltwater wedge migration of 170 and 110 m, respectively when considered individually, and up to 295 m (i.e., into the wellfield) when considered together. Despite the confining conditions, SLR resulted in wedge migration up to 55 m as the confining pressures were not sufficient to resist wedge movement. This is the first study to harness an integrated, surface‐subsurface hydrologic model to assess effects of coastal erosion and other hydroclimatic stressors on island aquifers, highlighting that climate change can drive extensive salinization of critical groundwater resources.
    Keywords aquifers ; climate change ; electrical resistance ; groundwater ; groundwater flow ; hydrologic models ; indigenous peoples ; mathematical models ; risk ; saline water ; saltwater intrusion ; sea level ; storms ; water supply ; Canada
    Language English
    Dates of publication 2024-01
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 5564-5
    ISSN 1944-7973 ; 0043-1397
    ISSN (online) 1944-7973
    ISSN 0043-1397
    DOI 10.1029/2023WR036394
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Prolonged FGF21 treatment increases energy expenditure and induces weight loss in obese mice independently of UCP1 and adrenergic signaling.

    Stanic, Sara / Bardova, Kristina / Janovska, Petra / Rossmeisl, Martin / Kopecky, Jan / Zouhar, Petr

    Biochemical pharmacology

    2024  Volume 221, Page(s) 116042

    Abstract: Fibroblast growth factor 21 (FGF21) reduces body weight, which was attributed to induced energy expenditure (EE). Conflicting data have been published on the role of uncoupling protein 1 (UCP1) in this effect. Therefore, we aimed to revisit the ... ...

    Abstract Fibroblast growth factor 21 (FGF21) reduces body weight, which was attributed to induced energy expenditure (EE). Conflicting data have been published on the role of uncoupling protein 1 (UCP1) in this effect. Therefore, we aimed to revisit the thermoregulatory effects of FGF21 and their implications for body weight regulation. We found that an 8-day treatment with FGF21 lowers body weight to similar extent in both wildtype (WT) and UCP1-deficient (KO) mice fed high-fat diet. In WT mice, this effect is solely due to increased EE, associated with a strong activation of UCP1 and with excess heat dissipated through the tail. This thermogenesis takes place in the interscapular region and can be attenuated by a β-adrenergic inhibitor propranolol. In KO mice, FGF21-induced weight loss correlates with a modest increase in EE, which is independent of adrenergic signaling, and with a reduced energy intake. Interestingly, the gene expression profile of interscapular brown adipose tissue (but not subcutaneous white adipose tissue) of KO mice is massively affected by FGF21, as shown by increased expression of genes encoding triacylglycerol/free fatty acid cycle enzymes. Thus, FGF21 elicits central thermogenic and pyretic effects followed by a concomitant increase in EE and body temperature, respectively. The associated weight loss is strongly dependent on UCP1-based thermogenesis. However, in the absence of UCP1, alternative mechanisms of energy dissipation may contribute, possibly based on futile triacylglycerol/free fatty acid cycling in brown adipose tissue and reduced food intake.
    MeSH term(s) Animals ; Mice ; Mice, Obese ; Uncoupling Protein 1/genetics ; Fatty Acids, Nonesterified ; Weight Loss ; Body Weight ; Energy Metabolism ; Adrenergic Agents ; Triglycerides ; Fibroblast Growth Factors
    Chemical Substances fibroblast growth factor 21 ; Uncoupling Protein 1 ; Fatty Acids, Nonesterified ; Adrenergic Agents ; Triglycerides ; Fibroblast Growth Factors (62031-54-3)
    Language English
    Publishing date 2024-02-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 208787-x
    ISSN 1873-2968 ; 0006-2952
    ISSN (online) 1873-2968
    ISSN 0006-2952
    DOI 10.1016/j.bcp.2024.116042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Storage method of multi-channel lidar data based on tree structure.

    Chen, Hao / Gao, Fei / Zhu, Qingsong / Yan, Qing / Hua, Dengxin / Stanič, Samo

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 9075

    Abstract: The multi-channel lidar has fast acquisition speed, large data volume, high dimension, and vital real-time storage, which makes it challenging to be met using the traditional lidar data storage methods. This paper presents a novel approach to storing the ...

    Abstract The multi-channel lidar has fast acquisition speed, large data volume, high dimension, and vital real-time storage, which makes it challenging to be met using the traditional lidar data storage methods. This paper presents a novel approach to storing the multi-channel lidar data based on the principle of the tree structure, the adjacency linked list, the binary data storage. In the proposed system, a tree structure is constructed by the four-dimensional structure of the multi-channel lidar data, and a data retrieval method of the multi-channel lidar data file is given. The results show that the proposed tree structure approach can save the storage capacity and improve the retrieval speed, which can meet the needs for efficient storage and retrieval of multi-channel lidar data, and improve the data storage utilization and the practicality of multi-channel lidar system.
    Language English
    Publishing date 2022-05-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-13138-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Lateral scanning Raman scattering lidar for accurate measurement of atmospheric temperature and water vapor from ground to height of interest.

    Yang, Fan / Gao, Fei / Zhang, Chengan / Li, Xiaoli / Gao, Xiong / Hua, Dengxin / Wang, Li / Xin, Wenhui / Stanič, Samo

    Optics letters

    2023  Volume 48, Issue 10, Page(s) 2595–2598

    Abstract: A novel lateral scanning Raman scattering lidar (LSRSL) system is proposed, aiming to realize the accurate measurement of atmospheric temperature and water vapor from the ground to a height of interest and to overcome the effect of a geometrical overlap ... ...

    Abstract A novel lateral scanning Raman scattering lidar (LSRSL) system is proposed, aiming to realize the accurate measurement of atmospheric temperature and water vapor from the ground to a height of interest and to overcome the effect of a geometrical overlap function of backward Raman scattering lidar. A configuration of the bistatic lidar is employed in the design of the LSRSL system, in which four horizontally aligned telescopes mounted on a steerable frame to construct the lateral receiving system are spatially separated to look at a vertical laser beam at a certain distance. Each telescope, combined with a narrowband interference filter, is utilized to detect the lateral scattering signals of the low- and high-quantum-number transitions of the pure rotational Raman scattering spectra and vibrational Raman scattering spectra of N
    Language English
    Publishing date 2023-05-15
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4794
    ISSN (online) 1539-4794
    DOI 10.1364/OL.488924
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Lateral scanning Raman scattering lidar for accurate measurement of atmospheric temperature and water vapor from ground to height of interest: publisher's note.

    Yang, Fan / Gao, Fei / Zhang, Chengan / Li, Xiaoli / Gao, Xiong / Hua, Dengxin / Wang, Li / Xin, Wenhui / Stanič, Samo

    Optics letters

    2023  Volume 48, Issue 11, Page(s) 2994

    Abstract: This publisher's note contains corrections to Opt. Lett.48, 2595 (2023).10.1364/OL.488924. ...

    Abstract This publisher's note contains corrections to Opt. Lett.48, 2595 (2023).10.1364/OL.488924.
    Language English
    Publishing date 2023-06-01
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4794
    ISSN (online) 1539-4794
    DOI 10.1364/OL.496000
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Effect of Different Compatibilization Systems on the Rheological, Mechanical and Morphological Properties of Polypropylene/Polystyrene Blends.

    Seier, Martina / Stanic, Sascha / Koch, Thomas / Archodoulaki, Vasiliki-Maria

    Polymers

    2020  Volume 12, Issue 10

    Abstract: The influence of reactive processing, non reactive and reactive copolymers on immiscible polypropylene (PP)-polystyrene (PS) blends with varying PS concentrations (10 wt.% and 25 wt.%) was evaluated by mechanical (tensile and tensile impact), rheological ...

    Abstract The influence of reactive processing, non reactive and reactive copolymers on immiscible polypropylene (PP)-polystyrene (PS) blends with varying PS concentrations (10 wt.% and 25 wt.%) was evaluated by mechanical (tensile and tensile impact), rheological (melt flow rate, extensional and dynamic rheology) and morphological (scanning electron microscopy) analysis. As an extended framework of the study, the creation of a link to industrial applicable processing conditions as well as an economically efficient use of compatibilzing agent were considered. For radical processed blends, a high improvement in melt strength was observed while non reactive copolymers exhibited a pronounced increase in toughness and ductility correlated with overall best phase homogeneity. Conversely, the influence of the reactive copolymer was quite different for the varied PS concentrations not allowing the assumption of a specific trend for resulting blend properties, but nevertheless in the case of a lower PS concentration the tensile impact strength exceeded the value of virgin PP. Since PS and PP are widely used, the findings of this work could not only be relevant for the generation of more versatile blends compared to virgin components but also for recycling purposes, allowing the enhancement of specific properties facilitating the production of more valuable secondary materials.
    Language English
    Publishing date 2020-10-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym12102335
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Improving Rheological and Mechanical Properties of Various Virgin and Recycled Polypropylenes by Blending with Long-Chain Branched Polypropylene.

    Stanic, Sascha / Koch, Thomas / Schmid, Klaus / Knaus, Simone / Archodoulaki, Vasiliki-Maria

    Polymers

    2021  Volume 13, Issue 7

    Abstract: Blends of two long-chain branched polypropylenes (LCB-PP) and five linear polypropylenes (L-PP) were prepared in a single screw extruder at 240 °C. The two LCB-PPs were self-created via reactive extrusion at 180 °C by using dimyristyl peroxydicarbonate ( ... ...

    Abstract Blends of two long-chain branched polypropylenes (LCB-PP) and five linear polypropylenes (L-PP) were prepared in a single screw extruder at 240 °C. The two LCB-PPs were self-created via reactive extrusion at 180 °C by using dimyristyl peroxydicarbonate (PODIC C126) and dilauroyl peroxide (LP) as peroxides. For blending two virgin and three recycled PPs like coffee caps, yoghurt cups and buckets with different melt flow rate (MFR) values were used. The influence of using blends was assessed by investigating the rheological (dynamic and extensional rheology) and mechanical properties (tensile test and impact tensile test). The dynamic rheology indicated that the molecular weight as well as the molecular weight distribution could be increased or broadened. Also the melt strength behavior could be improved by using the two peroxide modified LCB-PP blends on the basis of PODIC C126 or PEROXAN LP (dilauroyl peroxide). In addition, the mechanical properties were consistently enhanced or at least kept constant compared to the original material. In particular, the impact tensile strength but also the elongation at break could be increased considerably. This study showed that the blending of LCB-PP can increase the investigated properties and represents a promising option, especially when using recycled PP, which demonstrates a real "up-cycling" process.
    Language English
    Publishing date 2021-04-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym13071137
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The impact of RTOG 0614 and RTOG 0933 trials in routine clinical practice: The US Survey of Utilization of Memantine and IMRT planning for hippocampus sparing in patients receiving whole brain radiotherapy for brain metastases.

    Slade, Alexander N / Stanic, Sinisa

    Contemporary clinical trials

    2015  Volume 47, Page(s) 74–77

    Abstract: Introduction: Two recent clinical trials, phase III RTOG 0614 and phase II RTOG 0933, showed some effectiveness of Memantine and IMRT planning for hippocampus sparing, among patients receiving whole brain radiotherapy (WBRT) for brain metastases; ... ...

    Abstract Introduction: Two recent clinical trials, phase III RTOG 0614 and phase II RTOG 0933, showed some effectiveness of Memantine and IMRT planning for hippocampus sparing, among patients receiving whole brain radiotherapy (WBRT) for brain metastases; however, their use in routine clinical practice is unknown.
    Methods: A survey was sent to 1933 radiation oncologists in the US. Data collected included utilization of Memantine and hippocampus sparing, reasons for adoption and non-adoption, and demographic variables.
    Results: A total of 196 radiation oncologists responded to the survey, with 64% reporting using Memantine in almost none of the patients receiving WBRT for brain metastases, and only 11% considering Memantine for <10% of their patients. The most common reason for not using Memantine was a poor patient performance status, and limited life expectancy. Likewise, 56% of radiation oncologists would not change their clinical practice to include hippocampus sparing IMRT in patients receiving WBRT based on the results of RTOG 0933. Further validation of hippocampus sparing in a phase III trial was supported by 71% of radiation oncologists, whereas further exploration of Memantine for this purpose in a phase III trial was supported by 42%.
    Conclusions: At this time, the majority of surveyed radiation oncologists in the US do not use Memantine, or IMRT planning for hippocampus sparing in patients receiving WBRT. Further validation of the hippocampus sparing concept in a phase III trial was supported, before adopting it in routine clinical practice.
    MeSH term(s) Brain Neoplasms/radiotherapy ; Brain Neoplasms/secondary ; Clinical Trials, Phase II as Topic ; Clinical Trials, Phase III as Topic ; Cranial Irradiation ; Diffusion of Innovation ; Dopamine Agents/therapeutic use ; Hippocampus ; Humans ; Memantine/therapeutic use ; Organ Sparing Treatments ; Practice Patterns, Physicians'/statistics & numerical data ; Radiation Oncologists ; Radiotherapy Planning, Computer-Assisted/statistics & numerical data ; Radiotherapy, Intensity-Modulated/methods ; Surveys and Questionnaires
    Chemical Substances Dopamine Agents ; Memantine (W8O17SJF3T)
    Language English
    Publishing date 2015-12-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2182176-8
    ISSN 1559-2030 ; 1551-7144
    ISSN (online) 1559-2030
    ISSN 1551-7144
    DOI 10.1016/j.cct.2015.12.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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