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  1. Article: Characterisation of Putative Outer Membrane Proteins from

    Kamaruzaman, Intan Noor Aina / Staton, Gareth James / Ainsworth, Stuart / Carter, Stuart D / Evans, Nicholas James

    Microorganisms

    2024  Volume 12, Issue 2

    Abstract: Leptospirosis is a zoonotic bacterial disease affecting mammalian species worldwide. Cattle are a major susceptible host; infection with ... ...

    Abstract Leptospirosis is a zoonotic bacterial disease affecting mammalian species worldwide. Cattle are a major susceptible host; infection with pathogenic
    Language English
    Publishing date 2024-01-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms12020245
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: First cases of contagious ovine digital dermatitis in Germany.

    Tegtmeyer, Philip Christian / Staton, Gareth James / Evans, Nicholas James / Rohde, Judith / Punsmann, Teresa Maria / Ganter, Martin

    Acta veterinaria Scandinavica

    2020  Volume 62, Issue 1, Page(s) 46

    Abstract: Contagious ovine digital dermatitis (CODD) is a significant disease of the ovine foot characterised by severe lameness and progressive separation of the hoof horn capsule from the underlying tissue. Similar to bovine digital dermatitis (BDD), pathogenic ... ...

    Abstract Contagious ovine digital dermatitis (CODD) is a significant disease of the ovine foot characterised by severe lameness and progressive separation of the hoof horn capsule from the underlying tissue. Similar to bovine digital dermatitis (BDD), pathogenic members of the genus Treponema including the Treponema medium phylogroup, Treponema phagedenis phylogroup and Treponema pedis are frequently found together in CODD lesions. To date, CODD was only described in Ireland and the United Kingdom. In northern Germany, cases of an unusually severe lameness presented in a sheep flock that had been affected by footrot for several years. These cases were non-responsive to conventional footrot therapies, with some sheep exhibiting substantial lesions of the claw horn that resulted in horn detachment. Lesion swab samples were collected from both clinically affected and asymptomatic animals. In all clinically affected sheep, CODD-associated Treponema phylogroups were detected by polymerase chain reaction. This is the first report of CODD in Germany and mainland Europe, indicating a wider geographic spread than previously considered. In cases of severe lameness attributed to claw lesions in sheep that fail to respond to footrot treatment, CODD should be considered irrespective of geographic location.
    MeSH term(s) Animals ; Digital Dermatitis/microbiology ; Germany ; Polymerase Chain Reaction/veterinary ; Sheep ; Sheep Diseases/microbiology ; Treponema/classification ; Treponema/isolation & purification
    Language English
    Publishing date 2020-08-27
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 40137-7
    ISSN 1751-0147 ; 0044-605X
    ISSN (online) 1751-0147
    ISSN 0044-605X
    DOI 10.1186/s13028-020-00544-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 484: Show issues Location:
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  3. Article ; Online: Surveying bovine digital dermatitis and non-healing bovine foot lesions for the presence of

    Staton, Gareth James / Sullivan, Leigh Emma / Blowey, Roger W / Carter, Stuart D / Evans, Nicholas James

    The Veterinary record

    2020  Volume 186, Issue 14, Page(s) 450

    Abstract: Background: Non-healing bovine foot lesions, including non-healing white line disease, non-healing sole ulcer and toe necrosis, are an increasingly important cause of chronic lameness that are poorly responsive to treatment. Recent studies have ... ...

    Abstract Background: Non-healing bovine foot lesions, including non-healing white line disease, non-healing sole ulcer and toe necrosis, are an increasingly important cause of chronic lameness that are poorly responsive to treatment. Recent studies have demonstrated a high-level association between these non-healing lesions and the
    Methods: A PCR-based bacteriological survey of uncomplicated BDD lesions (n=10) and non-healing bovine foot lesions (n=10) targeting
    Results: P. endodontalis
    Conclusion: The data from this pilot study suggest that
    MeSH term(s) Animals ; Cattle ; Cattle Diseases/microbiology ; DNA, Bacterial/isolation & purification ; Digital Dermatitis/microbiology ; Female ; Fusobacterium Infections/microbiology ; Fusobacterium Infections/veterinary ; Fusobacterium necrophorum/genetics ; Fusobacterium necrophorum/isolation & purification ; Pilot Projects ; Polymerase Chain Reaction/veterinary ; Porphyromonas endodontalis/genetics ; Porphyromonas endodontalis/isolation & purification ; Syphilis/microbiology ; Syphilis/veterinary ; Treponema pallidum/genetics ; Treponema pallidum/isolation & purification ; Treponemal Infections/microbiology ; Treponemal Infections/veterinary ; United Kingdom
    Chemical Substances DNA, Bacterial
    Language English
    Publishing date 2020-02-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 390015-0
    ISSN 2042-7670 ; 0042-4900
    ISSN (online) 2042-7670
    ISSN 0042-4900
    DOI 10.1136/vr.105628
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 645: Show issues Location:
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  4. Article: Surveying bovine digital dermatitis and non‐healing bovine foot lesions for the presence of Fusobacterium necrophorum, Porphyromonas endodontalis and Treponema pallidum

    Staton, Gareth James / Sullivan, Leigh Emma / Blowey, Roger W / Carter, Stuart D / Evans, Nicholas James

    Veterinary record. 2020 Apr., v. 186, no. 14

    2020  

    Abstract: BACKGROUND: Non‐healing bovine foot lesions, including non‐healing white line disease, non‐healing sole ulcer and toe necrosis, are an increasingly important cause of chronic lameness that are poorly responsive to treatment. Recent studies have ... ...

    Abstract BACKGROUND: Non‐healing bovine foot lesions, including non‐healing white line disease, non‐healing sole ulcer and toe necrosis, are an increasingly important cause of chronic lameness that are poorly responsive to treatment. Recent studies have demonstrated a high‐level association between these non‐healing lesions and the Treponema phylogroups implicated in bovine digital dermatitis (BDD). However, a polymicrobial aetiology involving other gram‐stain‐negative anaerobes is suspected. METHODS: A PCR‐based bacteriological survey of uncomplicated BDD lesions (n=10) and non‐healing bovine foot lesions (n=10) targeting Fusobacterium necrophorum, Porphyromonas endodontalis, Dichelobacter nodosus and Treponema pallidum/T. paraluiscuniculi was performed. RESULTS: P. endodontalis DNA was detected in 80.0% of the non‐healing lesion biopsies (p=<0.001) but was entirely absent from uncomplicated BDD lesion biopsies. When compared to the BDD lesions, F. necrophorum was detected at a higher frequency in the non‐healing lesions (33.3% vs 70.0%, respectively), whereas D. nodosus was detected at a lower frequency (55.5% vs 20.0%, respectively). Conversely, T. pallidum/T. paraluiscuniculi DNA was not detected in either lesion type. CONCLUSION: The data from this pilot study suggest that P. endodontalis and F. necrophorum should be further investigated as potential aetiological agents of non‐healing bovine foot lesions. A failure to detect syphilis treponemes in either lesion type is reassuring given the potential public health implications such an infection would present.
    Keywords DNA ; Dichelobacter nodosus ; Fusobacterium necrophorum ; Porphyromonas endodontalis ; Treponema pallidum ; anaerobes ; cattle ; dermatitis ; lameness ; necrosis ; polymerase chain reaction ; public health ; surveys
    Language English
    Dates of publication 2020-04
    Size p. 450.
    Publishing place BMJ Publishing Group Limited
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 390015-0
    ISSN 2042-7670 ; 0042-4900
    ISSN (online) 2042-7670
    ISSN 0042-4900
    DOI 10.1136/vr.105628
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 3145: Show issues

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  5. Article: First cases of contagious ovine digital dermatitis in Germany

    Tegtmeyer, Philip Christian / Staton, Gareth James / Evans, Nicholas James / Rohde, Judith / Punsmann, Teresa Maria / Ganter, Martin

    Acta veterinaria scandinavica. 2020 Dec., v. 62, no. 1

    2020  

    Abstract: Contagious ovine digital dermatitis (CODD) is a significant disease of the ovine foot characterised by severe lameness and progressive separation of the hoof horn capsule from the underlying tissue. Similar to bovine digital dermatitis (BDD), pathogenic ... ...

    Abstract Contagious ovine digital dermatitis (CODD) is a significant disease of the ovine foot characterised by severe lameness and progressive separation of the hoof horn capsule from the underlying tissue. Similar to bovine digital dermatitis (BDD), pathogenic members of the genus Treponema including the Treponema medium phylogroup, Treponema phagedenis phylogroup and Treponema pedis are frequently found together in CODD lesions. To date, CODD was only described in Ireland and the United Kingdom. In northern Germany, cases of an unusually severe lameness presented in a sheep flock that had been affected by footrot for several years. These cases were non-responsive to conventional footrot therapies, with some sheep exhibiting substantial lesions of the claw horn that resulted in horn detachment. Lesion swab samples were collected from both clinically affected and asymptomatic animals. In all clinically affected sheep, CODD-associated Treponema phylogroups were detected by polymerase chain reaction. This is the first report of CODD in Germany and mainland Europe, indicating a wider geographic spread than previously considered. In cases of severe lameness attributed to claw lesions in sheep that fail to respond to footrot treatment, CODD should be considered irrespective of geographic location.
    Keywords Treponema medium ; Treponema phagedenis ; cattle ; claws ; flocks ; footrot ; hooves ; lameness ; polymerase chain reaction ; sheep ; Germany ; Ireland ; United Kingdom
    Language English
    Dates of publication 2020-12
    Size p. 46.
    Publishing place BioMed Central
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 40137-7
    ISSN 1751-0147 ; 0044-605X
    ISSN (online) 1751-0147
    ISSN 0044-605X
    DOI 10.1186/s13028-020-00544-0
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 484: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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