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  1. Article ; Online: Episodic and prospective memory difficulties in 13-year-old children born very preterm.

    Stedall, Paulina M / Spencer-Smith, Megan M / Lah, Suncica / Doyle, Lex W / Spittle, Alicia J / Burnett, Alice C / Anderson, Peter J

    Journal of the International Neuropsychological Society : JINS

    2022  Volume 29, Issue 3, Page(s) 257–265

    Abstract: Objectives: Children born very preterm (VP) are susceptible to a range of cognitive impairments, yet the effects of VP birth on long-term, episodic, and prospective memory remains unclear. This study examined episodic and prospective memory functioning ... ...

    Abstract Objectives: Children born very preterm (VP) are susceptible to a range of cognitive impairments, yet the effects of VP birth on long-term, episodic, and prospective memory remains unclear. This study examined episodic and prospective memory functioning in children born VP compared with their term-born counterparts at 13 years.
    Method: VP (
    Results: The VP group performed worse on all measures of verbal and visuospatial episodic memory than the term group. While there were no group differences in event-based or long-term prospective memory, the VP group performed worse on time-based and short-term prospective memory tasks than term-born counterparts. Parents of children born VP reported more everyday memory difficulties than parents of children born at term, with parent-ratings indicating significantly elevated rates of everyday memory challenges in children born VP.
    Conclusions: Children born VP warrant long-term surveillance, as challenges associated with VP birth include memory difficulties at 13 years. This study highlights the need for greater research and clinical attention into childhood functional memory outcomes.
    MeSH term(s) Infant, Newborn ; Humans ; Child ; Adolescent ; Infant, Extremely Premature ; Memory, Episodic ; Memory, Short-Term ; Gestational Age ; Attention
    Language English
    Publishing date 2022-04-07
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1230632-0
    ISSN 1469-7661 ; 1355-6177
    ISSN (online) 1469-7661
    ISSN 1355-6177
    DOI 10.1017/S1355617722000170
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Thirteen-Year Outcomes of a Randomized Clinical Trial of Early Preventive Care for Very Preterm Infants and Their Parents.

    Stedall, Paulina M / Spencer-Smith, Megan M / Mainzer, Rheanna M / Treyvaud, Karli / Burnett, Alice C / Doyle, Lex W / Spittle, Alicia J / Anderson, Peter J

    The Journal of pediatrics

    2022  Volume 246, Page(s) 80–88.e4

    Abstract: Objective: To evaluate 13-year outcomes of a randomized controlled trial of preventive care (VIBeS Plus) for infants born very preterm and their parents and examine whether possible effects of intervention varied by family social risk.: Study design: ...

    Abstract Objective: To evaluate 13-year outcomes of a randomized controlled trial of preventive care (VIBeS Plus) for infants born very preterm and their parents and examine whether possible effects of intervention varied by family social risk.
    Study design: Families were randomized to an intervention arm (n = 61) or a standard care arm (n = 59). The intervention was delivered at home by psychologists and physiotherapists over the infants' first year, focusing on infant development and parental mental health. At 13 years corrected age, cognitive, motor, and behavioral outcomes, and parental mental health were assessed. Primary estimands were between-group mean differences, estimated using multiple imputed regression models.
    Results: Follow-up included 81 surviving children (69%). There was little evidence of benefits of the intervention for IQ, attention, executive functioning, working memory, and academic skills regardless of level of social risk. Specifically, mean differences in adolescent cognitive outcomes ranged from -2.0 units (95% CI, -9.9 to 5.9) in favor of standard treatment to 5.1 units (95% CI, -2.3 to 12.5) favoring the intervention. A group-by-social risk interaction was observed only for adolescent motor outcomes, with mean differences favoring the intervention for those at higher social risk (balance, 4.9; 95% CI, 1.3-8.5; total motor, 3.2; 95% CI, 0.3-6.2), but not those at lower social risk (balance, -0.3; 95% CI, -2.4 to 1.9; total motor, 0.03; 95% CI, -1.9 to 2.0). Mean differences in adolescent behavior and parental mental health ranged from -6.6 (95% CI -13.8, 0.5) to -0.2 (95% CI, -1.9 to 1.4) and -1.8 (95% CI, -4.1 to 0.6) to -1.7 (95% CI, -4.3 to 1.0), respectively, indicating a pattern of fewer symptoms in the intervention group.
    Conclusions: Benefits of the intervention persisted for adolescent behavior, with better motor outcomes observed in those from socially disadvantaged families. Replication with larger samples, multiple informant reports, and assessment of quality of life-related outcomes is warranted.
    Trial registration: http://www.anzctr.org.au/: ACTRN12605000492651.
    MeSH term(s) Adolescent ; Child ; Child Development ; Female ; Fetal Growth Retardation ; Humans ; Infant ; Infant, Newborn ; Infant, Premature ; Infant, Premature, Diseases/prevention & control ; Parents/psychology ; Quality of Life
    Language English
    Publishing date 2022-03-16
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2022.03.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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