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  1. Article: A Drop of Water.

    Steele, J D

    The Bistoury

    2023  Volume 5, Issue 1, Page(s) 12–13

    Language English
    Publishing date 2023-04-13
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: How Can We Incorporate Visual Evidence into the History of the Astral Sciences in Mesopotamia?

    Steele, John

    NTM

    2020  Volume 28, Issue 3, Page(s) 305–324

    Abstract: Significant progress has been made in understanding Mesopotamian astronomy and astrology since the decipherment of cuneiform tablets containing astronomical and astrological texts in the late nineteenth century. However, until now few attempts have been ... ...

    Title translation Wie können wir visuelle Anhaltspunkte in die Geschichte der mesopotamischen Astrowissenschaften integrieren?
    Abstract Significant progress has been made in understanding Mesopotamian astronomy and astrology since the decipherment of cuneiform tablets containing astronomical and astrological texts in the late nineteenth century. However, until now few attempts have been made to write a detailed history of the Mesopotamian astral sciences as opposed to detailed studies of particular texts and types of astronomy or astrology. My aim in this paper is to present some ideas of how such a history should be written and in particular to consider if and how visual evidence can be brought alongside textual evidence in the writing of this history.
    Language English
    Publishing date 2020-04-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 201410-5
    ISSN 1420-9144 ; 0036-6978
    ISSN (online) 1420-9144
    ISSN 0036-6978
    DOI 10.1007/s00048-020-00242-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Relative Difficulty in the Acquisition of the Phonetic Parameters of Obstruent Coda Voicing: Evidence from Mandarin-Speaking Learners of French.

    Patience, Matthew / Steele, Jeffrey

    Language and speech

    2022  Volume 66, Issue 3, Page(s) 625–651

    Abstract: A recurring finding of research on the L2 acquisition of coda obstruent voicing is that, in terms of the phonetic parameters that serve to realize the voicing contrast, learners are overwhelmingly more accurate with duration than the voicing of the ... ...

    Abstract A recurring finding of research on the L2 acquisition of coda obstruent voicing is that, in terms of the phonetic parameters that serve to realize the voicing contrast, learners are overwhelmingly more accurate with duration than the voicing of the obstruent itself. The current work expands our understanding of this asymmetry in two ways. First, as previous studies have focused almost exclusively on learners of English, we investigate here whether L2 learners' superior production of duration is also found among learners of other target languages via a study of Mandarin-speaking learners' production of French stop and fricative codas. Results from 18 Mandarin-speaking learners of French, primarily of beginner and intermediate proficiency who completed a sentence reading task, parallel those of previous studies with greater accuracy observed for vowel duration than the laryngeal voicing of the obstruent. Second, we explore potential sources of this asymmetry, in particular, the roles of L1 experience as well as of universal factors, namely, the relative perceptual salience of duration versus voicing, and the articulatory difficulty of voicing obstruents.
    MeSH term(s) Humans ; Phonetics ; Language ; Voice ; Reading ; Larynx
    Language English
    Publishing date 2022-09-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 3312-1
    ISSN 1756-6053 ; 0023-8309
    ISSN (online) 1756-6053
    ISSN 0023-8309
    DOI 10.1177/00238309221114143
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Laboratory Hints.

    Steele, J F

    The American journal of dental science

    2019  Volume 37, Issue 6, Page(s) 440

    Language English
    Publishing date 2019-02-12
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Home-Made Clamp and Matrixes.

    Steele, J F

    The American journal of dental science

    2019  Volume 35, Issue 12, Page(s) 236

    Language English
    Publishing date 2019-02-12
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Large Malignant Testicular/Paratesticular Tumors in Adolescence: Assessment of Gross Tumor Size in a Vulnerable Age Group.

    Stechschulte, Ava G / Bakker, Andrea C / Steele, Jasmine / Vargas, Sara O

    Annals of clinical and laboratory science

    2024  Volume 54, Issue 1, Page(s) 3–8

    Abstract: Objective: We hypothesized that reticence to address a groin mass may result in late presentation of testicular/paratesticular malignancy in early puberty through adolescence.: Methods: Malignant testicular and paratesticular tumors (malignant germ ... ...

    Abstract Objective: We hypothesized that reticence to address a groin mass may result in late presentation of testicular/paratesticular malignancy in early puberty through adolescence.
    Methods: Malignant testicular and paratesticular tumors (malignant germ cell tumors and rhabdomyosarcomas) diagnosed at our institution from 1994-2023 for patients aged 11-20 were included. Clinicopathologic features were recorded, and statistically analyzed.
    Results: Eighty-five cases were identified. Patient ages ranged from 11 to 20 years (mean 17 years, median 16 years). The greatest tumor dimension ranged from 0.8 to 18.0 cm (mean 4.4 cm, median 3.5 cm). Ten tumors (11.8% of cases) were ≥10.0 cm. In the 11-13-year-old age group, 100% of tumors (3/3) were ≥10 cm. The proportion of tumors ≥10 cm was significantly higher in the 11-13-year-old age group than in either the 14-16-year-old (
    Conclusion: This adolescent cohort with malignant testicular and paratesticular tumors showed a high proportion (11.8%) of very large (≥10 cm) tumors. Although the reasons are unknown and likely multifactorial, this study suggests that adolescents, particularly the 11-13 year age group, are a vulnerable population.
    MeSH term(s) Male ; Humans ; Adolescent ; Child ; Young Adult ; Adult ; Testicular Neoplasms/diagnosis ; Genital Neoplasms, Male ; Neoplasms, Germ Cell and Embryonal
    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 193092-8
    ISSN 1550-8080 ; 0091-7370 ; 0095-8905
    ISSN (online) 1550-8080
    ISSN 0091-7370 ; 0095-8905
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Radiomics Machine Learning Analysis of Clear Cell Renal Cell Carcinoma for Tumour Grade Prediction Based on Intra-Tumoural Sub-Region Heterogeneity.

    Alhussaini, Abeer J / Steele, J Douglas / Jawli, Adel / Nabi, Ghulam

    Cancers

    2024  Volume 16, Issue 8

    Abstract: Background: Renal cancers are among the top ten causes of cancer-specific mortality, of which the ccRCC subtype is responsible for most cases. The grading of ccRCC is important in determining tumour aggressiveness and clinical management.: Objectives!# ...

    Abstract Background: Renal cancers are among the top ten causes of cancer-specific mortality, of which the ccRCC subtype is responsible for most cases. The grading of ccRCC is important in determining tumour aggressiveness and clinical management.
    Objectives: The objectives of this research were to predict the WHO/ISUP grade of ccRCC pre-operatively and characterise the heterogeneity of tumour sub-regions using radiomics and ML models, including comparison with pre-operative biopsy-determined grading in a sub-group.
    Methods: Data were obtained from multiple institutions across two countries, including 391 patients with pathologically proven ccRCC. For analysis, the data were separated into four cohorts. Cohorts 1 and 2 included data from the respective institutions from the two countries, cohort 3 was the combined data from both cohort 1 and 2, and cohort 4 was a subset of cohort 1, for which both the biopsy and subsequent histology from resection (partial or total nephrectomy) were available. 3D image segmentation was carried out to derive a voxel of interest (VOI) mask. Radiomics features were then extracted from the contrast-enhanced images, and the data were normalised. The Pearson correlation coefficient and the XGBoost model were used to reduce the dimensionality of the features. Thereafter, 11 ML algorithms were implemented for the purpose of predicting the ccRCC grade and characterising the heterogeneity of sub-regions in the tumours.
    Results: For cohort 1, the 50% tumour core and 25% tumour periphery exhibited the best performance, with an average AUC of 77.9% and 78.6%, respectively. The 50% tumour core presented the highest performance in cohorts 2 and 3, with average AUC values of 87.6% and 76.9%, respectively. With the 25% periphery, cohort 4 showed AUC values of 95.0% and 80.0% for grade prediction when using internal and external validation, respectively, while biopsy histology had an AUC of 31.0% for the classification with the final grade of resection histology as a reference standard. The CatBoost classifier was the best for each of the four cohorts with an average AUC of 80.0%, 86.5%, 77.0% and 90.3% for cohorts 1, 2, 3 and 4 respectively.
    Conclusions: Radiomics signatures combined with ML have the potential to predict the WHO/ISUP grade of ccRCC with superior performance, when compared to pre-operative biopsy. Moreover, tumour sub-regions contain useful information that should be analysed independently when determining the tumour grade. Therefore, it is possible to distinguish the grade of ccRCC pre-operatively to improve patient care and management.
    Language English
    Publishing date 2024-04-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers16081454
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: "I Felt I Was Actually Inside the Movie" An Exploratory Study into Children's Views of Staging a Physically Active Experience, with Implications for Future Interventions.

    Budzynski-Seymour, Emily / Jones, Michelle / Steele, James

    International journal of environmental research and public health

    2023  Volume 20, Issue 4

    Abstract: Current levels of inactivity suggest novel approaches are needed to engage children in physical activity (PA), and enjoyment is a strong motivator for children's PA engagement. ... ...

    Abstract Current levels of inactivity suggest novel approaches are needed to engage children in physical activity (PA), and enjoyment is a strong motivator for children's PA engagement. A
    MeSH term(s) Male ; Female ; Humans ; Child ; Motion Pictures ; Exercise/physiology ; Focus Groups ; Emotions ; Sedentary Behavior
    Language English
    Publishing date 2023-02-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20043624
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Blunted Expected Reward Value Signals in Binge Alcohol Drinkers.

    Tolomeo, Serenella / Baldacchino, Alex / Steele, J Douglas

    The Journal of neuroscience : the official journal of the Society for Neuroscience

    2023  Volume 43, Issue 31, Page(s) 5685–5692

    Abstract: Alcohol-related morbidities and mortality are highly prevalent, increasing the burden to societies and health systems with 3 million deaths globally each year in young adults directly attributable to alcohol. Cue-induced alcohol craving has been ... ...

    Abstract Alcohol-related morbidities and mortality are highly prevalent, increasing the burden to societies and health systems with 3 million deaths globally each year in young adults directly attributable to alcohol. Cue-induced alcohol craving has been formulated as a type of aberrant associative learning, modeled using temporal difference theory with an expected reward value (ERV) linked to craving. Clinically, although harmful use of alcohol is associated with increased time spent obtaining and using alcohol, it is also associated with self-neglect. The latter implies that the motivational aspects of nonalcohol stimuli are blunted. Using an instrumental learning task with non-alcohol-related stimuli, here, we tested hypotheses that the encoding of cue signals (ERV) predicting reward delivery would be blunted in binge alcohol drinkers in both sexes. We also predicted that for the binge drinking group alone, ratings of problematic alcohol use would correlate with abnormal ERV signals consistent with between groups (i.e., binge drinkers vs controls) abnormalities. Our results support our hypotheses with the ERV (nonalcohol cue) signal blunted in binge drinkers and with the magnitude of the abnormality correlating with ratings of problematic alcohol use. This implies that consistent with hypotheses, the motivational aspects of non-alcohol-related stimuli are blunted in binge drinkers. A better understanding of the mechanisms of harmful alcohol use will, in time, facilitate the development of more effective interventions, which should aim to decrease the motivational value of alcohol and increase the motivational value of non-alcohol-related stimuli.
    MeSH term(s) Male ; Female ; Young Adult ; Humans ; Binge Drinking ; Alcohol Drinking ; Ethanol ; Reward ; Craving
    Chemical Substances Ethanol (3K9958V90M)
    Language English
    Publishing date 2023-01-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 604637-x
    ISSN 1529-2401 ; 0270-6474
    ISSN (online) 1529-2401
    ISSN 0270-6474
    DOI 10.1523/JNEUROSCI.2157-21.2022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Articulatory Insights into the L2 Acquisition of English-/l/ Allophony.

    Colantoni, Laura / Kochetov, Alexei / Steele, Jeffrey

    Language and speech

    2023  , Page(s) 238309231200629

    Abstract: In many English varieties, /l/ is produced differently in onsets and codas. Compared with "light" syllable-initial realizations, "dark" syllable-final variants involve reduced tongue tip-alveolar ridge contact and a raised/retracted tongue dorsum. We ... ...

    Abstract In many English varieties, /l/ is produced differently in onsets and codas. Compared with "light" syllable-initial realizations, "dark" syllable-final variants involve reduced tongue tip-alveolar ridge contact and a raised/retracted tongue dorsum. We investigate whether native French and Spanish speakers whose L1 lacks such positionally conditioned variation can acquire English-/l/ allophony, testing the hypotheses that (1) the allophonic pattern will be acquired by both groups but (2) learners will differ from native speakers in their phonetic implementation, particularly in codas; and (3) French-speaking learners will outperform their Spanish-speaking counterparts. The production of syllable-initial and -final /l/ (singletons and clusters) in words read in isolation and a carrier sentence by 4 French- and 3 Spanish-speaking learners as well as three native English speakers was analyzed via electropalatography and acoustic analysis. While some learners produced distinct onset and coda variants and all learners had moved away to some extent from their L1 production, they differed from the native speakers in certain ways. Moreover, between- and within-group variability was observed including greater target-like anterior and posterior contact reduction in codas in the L1 French versus L1 Spanish group and generally higher F2 values in both learner groups compared with their native speaker peers. A comparison of the learners' L1 and L2 production revealed L1-based patterns of positional reduction of the tongue tip and dorsum gestures. We conclude by addressing the contributions of EPG to our understanding of L2 speech and highlight avenues for future research including the study of both linguistic and speaker variables.
    Language English
    Publishing date 2023-11-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 3312-1
    ISSN 1756-6053 ; 0023-8309
    ISSN (online) 1756-6053
    ISSN 0023-8309
    DOI 10.1177/00238309231200629
    Database MEDical Literature Analysis and Retrieval System OnLINE

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