Article: Three-component reaction for the synthesis of diverse β-unsaturated α-amino esters
Tetrahedron. 2014 May 20, v. 70
2014
Abstract: We describe an efficient multicomponent reaction for the preparation of β-unsaturated α-amino esters by ytterbium triflate catalyzed reaction of potassium organotrifluoroborate salts, aniline and ethyl glyoxalate. The synthetic viability of this ... ...
| Abstract | We describe an efficient multicomponent reaction for the preparation of β-unsaturated α-amino esters by ytterbium triflate catalyzed reaction of potassium organotrifluoroborate salts, aniline and ethyl glyoxalate. The synthetic viability of this protocol was demonstrated by moderate to high yields, short reaction time ranging from 0.5 to 12 h, and efficiency with respect to substrate scope. |
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| Keywords | aniline ; chemical reactions ; chemical structure ; esters ; salts | |||||
| Language | English | |||||
| Dates of publication | 2014-0520 | |||||
| Size | p. 3243-3248. | |||||
| Publishing place | Elsevier Ltd | |||||
| Document type | Article | |||||
| ZDB-ID | 204285-x | |||||
| ISSN | 1464-5416 ; 0040-4020 ; 0563-2064 | |||||
| ISSN (online) | 1464-5416 | |||||
| ISSN | 0040-4020 ; 0563-2064 | |||||
| DOI | 10.1016/j.tet.2013.11.107 | |||||
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| Database | NAL-Catalogue (AGRICOLA) |
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