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  1. Article ; Online: MORTALITY OF HOSPITALIZED PATIENTS WITH SARS-COV-2 INFECTION IN UNIVERSITY TERTIARY CARE OF ITALY

    Stefania Zerbo

    Euromediterranean Biomedical Journal, Vol 18, Iss 18, Pp 84-

    2023  Volume 89

    Abstract: This study on the mortality trends in hospitalized patients at the University tertiary care Hospital “P. Giaccone” in Palermo (Italy) affected by the SARS-CoV-2 analyses clinical information from necroscopy medical record and death certificates in order ... ...

    Abstract This study on the mortality trends in hospitalized patients at the University tertiary care Hospital “P. Giaccone” in Palermo (Italy) affected by the SARS-CoV-2 analyses clinical information from necroscopy medical record and death certificates in order to: 1) discern patients who died due to COVID-19 (understood as the immediate cause of death, reported in death certificates, the course of the disease documented within a causal chain (immediate and underlying cause) and patients who died of other diseases with SARS-CoV-2 infection as a comorbidity; 2)evaluate the pre-existing conditions of SARS-CoV-2 positive patients and their influence on the mortality rate with reference to the Charlson Comorbidity Index; 3)compare variables concerning patients who died at the University Hospital of Palermo, with data from the National Institute of Health during the analyzed period, in order to strengthen or refute the hypotheses of other studies or to bring in new findings. The results of this retrospective study confirm, in public health terms, the importance of proper certification of cause of death, complete with indications of comorbidities and complications, as it is of fundamental value from both an epidemiological and medico-legal point of view.
    Keywords covid-19 ; mortality ; frailty ; comorbidity ; tertiary care ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2023-08-01T00:00:00Z
    Publisher Associazione Italiana Giovani Medici
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: An Overview on the Use of miRNAs as Possible Forensic Biomarkers for the Diagnosis of Traumatic Brain Injury

    Giuseppe Davide Albano / Chiara Stassi / Antonina Argo / Stefania Zerbo

    International Journal of Molecular Sciences, Vol 24, Iss 6503, p

    2023  Volume 6503

    Abstract: Determining the cause of death is one of the main goals of forensic pathology. However, conditions can occur in which common approaches—external inspection, autopsy, histology, etc.—might not be conclusive. With the advancement of molecular biology, ... ...

    Abstract Determining the cause of death is one of the main goals of forensic pathology. However, conditions can occur in which common approaches—external inspection, autopsy, histology, etc.—might not be conclusive. With the advancement of molecular biology, several investigative techniques have been developed over the years, and the application as approaches complementary to routine procedures has proved useful in these cases. In this context, microRNA (miRNA) profiling has attracted increasing interest due to these molecules’ ability to regulate physiological and pathological processes. The evidence of differential miRNA expression in both animal models and human samples of traumatic brain injury (TBI) has laid the basis for comprehension of the underlying pathophysiological mechanisms, thus allowing us to identify some of them as possible TBI diagnostic biomarkers. The present narrative review aims to explore the primary miRNAs involved in the mechanisms underlying TBI, which could be considered for future evaluation as possible markers in a post mortem setting.
    Keywords traumatic brain injury ; miRNA ; forensic ; autopsy ; biomarkers ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: COVID-19 Vaccination in Pediatric Population

    Clio Bilotta / Giulio Perrone / Stefania Zerbo / Antonina Argo

    Frontiers in Public Health, Vol

    A Necessity or Obstruction to the Protection of the Right to Health? Biojuridical Perspective

    2022  Volume 10

    Abstract: One of the most recently debated topics worldwide is the mass vaccination of children against coronavirus disease 2019 (COVID-19). Next, the risk/benefit ratio of COVID-19 vaccination and infection in children are compared. Nonetheless, the real question ...

    Abstract One of the most recently debated topics worldwide is the mass vaccination of children against coronavirus disease 2019 (COVID-19). Next, the risk/benefit ratio of COVID-19 vaccination and infection in children are compared. Nonetheless, the real question in this debate is as follows: Does the vaccine represent a necessary tool or is it an obstacle in protecting the right to health? From a public health point of view, the Supreme Court of Nova Scotia, in Canada, recommends COVID-19 vaccination in the pediatric population. Based on Article 25 of the Draft Articles on State responsibility, vaccination can be considered a social act necessary for protecting the individual's right to health. The 1989 New York Convention on the Rights of the Child and the European Regulation number 219/1111 state that the opinion of a minor aged >12 years is considerable. However, this validity of opinion is related to age and degree of discernment. The onset of adverse events following the administration of the COVID-19 vaccine may lead to compensation in the near future. Recent studies have identified a new COVID-19-related pediatric pathology, known as multisystem inflammatory syndrome. Other studies have demonstrated that myocarditis in the pediatric population might occur following COVID-19 vaccine administration. In June 2021 in the USA, the Center for Control and Prevention of Infectious Diseases Advisory Committee on Immunization Practices declared that the benefits of vaccination against COVID-19 in the pediatric population outweighed the risks. In the meantime, whereas the bioethical debate remains open, monitoring the real risk/benefit ratio of vaccination in the pediatric population is crucial.
    Keywords COVID-19 vaccination in pediatric population: bioethical controversy COVID-19 vaccination ; pediatric population ; children ; right to health ; bioethical controversy ; Public aspects of medicine ; RA1-1270
    Subject code 300
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: The Chain of Custody in the Era of Modern Forensics

    Tommaso D’Anna / Maria Puntarello / Giovanni Cannella / Giovanni Scalzo / Roberto Buscemi / Stefania Zerbo / Antonina Argo

    Healthcare, Vol 11, Iss 634, p

    From the Classic Procedures for Gathering Evidence to the New Challenges Related to Digital Data

    2023  Volume 634

    Abstract: The purpose of this work is to renew the interest and attention for the chain of custody in forensic medicine, its establishment and maintenance, protecting the integrity and validity of evidence as well as to analyze how over time the establishment of ... ...

    Abstract The purpose of this work is to renew the interest and attention for the chain of custody in forensic medicine, its establishment and maintenance, protecting the integrity and validity of evidence as well as to analyze how over time the establishment of the chain of custody and the collection of evidence has evolved also in function of the advent of technology and the use of electronic devices connected to the network. The analysis of the various aspects of the chain of custody demonstrates how necessary it is for the professional figures involved in the phases of the investigation (especially those who manage the evidence and who have, therefore, designated the assignment) to know the procedures to follow, trace the movement and the handling of objects subjected to seizure, also for the purposes of toxicological and/or histological investigations. The knowledge of interferences or complications helps to reduce errors and safeguard the validity of the evidence, assuring the proceeding judicial authority that the evidence is authentic and that it is, in other words, the same evidence seized at the scene of the crime. Furthermore, the issue is particularly felt today, with the recent need to guarantee the originality of digital data. Following a careful review and analysis of the literature currently available in this regard, it is worth adding that further efforts are needed to formulate internationally validated guidelines, harmonizing the different reference criteria in forensic science and medical areas, given the current absence of good international practices valid in the field and applicable both in the case of physical evidence and in the case of seizure of digital evidence.
    Keywords forensics ; evidence ; chain ; custody ; digital data ; Medicine ; R
    Subject code 940
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: The risk of the ‘prison-emptying’ effect in Italy due to the Covid-19 pandemic

    Ginevra Malta, Stefania Zerbo, Antonina Argo

    2020  

    Abstract: People who live and work or are detained inside restricted communities (including prisons) need to be considered as they are at a high risk of becoming infected with Covid-19 during this pandemic.1 InItaly, the spread of Covid-19 has provoked numerous ... ...

    Abstract People who live and work or are detained inside restricted communities (including prisons) need to be considered as they are at a high risk of becoming infected with Covid-19 during this pandemic.1 InItaly, the spread of Covid-19 has provoked numerous riots within the prisons and local detention centres, and there is a consequent increase in requests for inmates to be released and detained at home
    Keywords Covid-19 ; prison ; Settore MED/43 - Medicina Legale ; covid19
    Language English
    Publishing country it
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Covid-19: A new challenge for forensic medicine.

    Stefania, Zerbo / Ginevra, Malta / Elvira, Ventura Spagnolo / Antonina, Argo

    The Medico-legal journal

    2020  Volume 88, Issue 2, Page(s) 104–105

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Disease Transmission, Infectious/prevention & control ; Forensic Medicine/organization & administration ; Forensic Pathology/organization & administration ; Humans ; Infection Control/organization & administration ; Italy ; Medical Staff, Hospital ; Pandemics ; Pneumonia, Viral ; Practice Patterns, Physicians'/organization & administration ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-21
    Publishing country England
    Document type Letter
    ZDB-ID 390918-9
    ISSN 2042-1834 ; 0025-8172
    ISSN (online) 2042-1834
    ISSN 0025-8172
    DOI 10.1177/0025817220923696
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Perioperative and anesthetic deaths

    Antonina Argo / Stefania Zerbo / Antonietta Lanzarone / Roberto Buscemi / Roberta Roccuzzo / Steven B. Karch

    Egyptian Journal of Forensic Sciences, Vol 9, Iss 1, Pp 1-

    toxicological and medico legal aspects

    2019  Volume 12

    Abstract: Abstract Background Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in ... ...

    Abstract Abstract Background Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in anesthesiology. In this paper, some of these perioperative (PO) fatal adverse events are investigated in terms of health responsibility. Selective literature research in several data bases, concerning perioperative and anesthetic deaths and medical responsibility, was performed. Main text A generally accepted definition of the anesthesia and perioperatory-related death still remains one of the major concerns in forensic pathology, and the terms “operative deaths” and “anesthetic deaths” are usually applied inaccurately within the medico-legal literature. Such events involve comprehensively PO fatalities and allow for subtle separation of natural and unnatural death, at least from the prospective of forensic pathology. Iatrogenic deaths in this field can be separated into some major categories, as attributable to previous patient’s unfavorable conditions or depending from surgical procedure per se (such as PO cardiac and cerebrovascular events). In this review, the authors carried out syntheses of specific research areas regarding epidemiology, complications of general and spinal anesthetic, failure in airway management and patient’s circulatory homeostasis, and adverse drugs reactions; analysis considering the challenge of anesthetic-related mortality, epidemiology and classifications, by indicating causal chain of death, in respect of both contributing and associated anesthetic and surgery facts. Conclusions Perioperative quality control programs and its relevance for medico-legal evaluation are emphasized as, although mortality rates have decreased worldwide over the last decades, however, preventable drug-related deaths still happen. Such fatal events have to be considered within the field of forensic pathology experts, with regard of malpractice claims, to implement a ...
    Keywords Anesthesia ; Causal chain ; Drugs ; Epidemiology ; Errors ; Fatalities ; Law in general. Comparative and uniform law. Jurisprudence ; K1-7720 ; Medicine (General) ; R5-920
    Language English
    Publishing date 2019-05-01T00:00:00Z
    Publisher SpringerOpen
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: COVID-19 Pandemic

    Luigi Cirrincione / Fulvio Plescia / Caterina Ledda / Venerando Rapisarda / Daniela Martorana / Guido Lacca / Antonina Argo / Stefania Zerbo / Ermanno Vitale / Denis Vinnikov / Emanuele Cannizzaro

    Sustainability, Vol 14, Iss 4766, p

    New Prevention and Protection Measures

    2022  Volume 4766

    Abstract: As of the end of February 2021, more than 420,000,000 confirmed cases of COVID-19 have been reported worldwide, with 5,856,224 deaths. Transmission of the different genetically engineered variants of SARS-CoV-2, which have been isolated since the ... ...

    Abstract As of the end of February 2021, more than 420,000,000 confirmed cases of COVID-19 have been reported worldwide, with 5,856,224 deaths. Transmission of the different genetically engineered variants of SARS-CoV-2, which have been isolated since the beginning of the pandemic, occurs from one infected person to another by the same means: the airborne route, indirect contact, and occasionally the fecal–oral route. Infection is asymptomatic or may present with flulike symptoms such as fever, cough, and mild to moderate and severe respiratory distress, requiring hospitalization and assisted ventilation support. To control the spread of COVID-19, the World Health Organization (WHO) and Centers for Disease Control and Prevention (CDC) have indicated that the appropriate use of personal protective equipment (PPE), as well as the adoption of effective hygiene systems, is one of the primary prevention measures for the entire population. Companies and institutions around the world are therefore trying to find the best ways to reorganize their operations, minimizing the risk of infection among their employees, in order to protect their health and prevent internal outbreaks of SARS-CoV-2, including through the development of new technologies that could also be an innovative and driving factor for the relaunch of companies in a more sustainable, ethically correct, and safe for the health of employees perspective. On the basis of the above premises, in view of the coexistence with SARS-CoV-2 that will most likely accompany us in the coming years, and in view of the vaccination campaign adopted worldwide, the purpose of our narrative review is to update the previous operational protocols with the latest scientific knowledge to be adopted in the workplace even when the emergency crisis is over.
    Keywords organizational measures ; environmental measures ; pandemic ; infection ; work ; occupational medicine ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Covid-19

    Stefania, Zerbo / Ginevra, Malta / Elvira, Ventura Spagnolo / Antonina, Argo

    Medico-Legal Journal

    A new challenge for forensic medicine

    2020  Volume 88, Issue 2, Page(s) 104–105

    Keywords General Medicine ; covid19
    Language English
    Publisher SAGE Publications
    Publishing country us
    Document type Article ; Online
    ZDB-ID 390918-9
    ISSN 2042-1834 ; 0025-8172
    ISSN (online) 2042-1834
    ISSN 0025-8172
    DOI 10.1177/0025817220923696
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Un I Zs.381: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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