Article ; Online: Prevention of Frey's Syndrome with the Use of Porcine Dermal Collagen Graft: Retrospective Analysis of 76 "Formal" Parotidectomies for Benign Pathologies.
The Annals of otology, rhinology, and laryngology
2021 Volume 130, Issue 9, Page(s) 1036–1043
Abstract: Background: Frey's syndrome is a well-known complication of parotid surgery; its prevention may be achieved by the use of an interpositional barrier between the overlying flaps and the exposed parenchymal bed of parotid gland. The aim of this study was ... ...
| Abstract | Background: Frey's syndrome is a well-known complication of parotid surgery; its prevention may be achieved by the use of an interpositional barrier between the overlying flaps and the exposed parenchymal bed of parotid gland. The aim of this study was to retrospectively evaluate clinical outcomes with and without the interpositional placement of a porcine dermal collagen graft (PDCG) for prevention of syndrome occurrence. Methods: We conducted a 20-year retrospective study including the patients who had undergone "formal" (superficial, total, or subtotal) parotidectomies for benign pathologies. The inclusion criteria also involved patients that were (i) regularly monitored about clinical symptoms related to syndrome, and (ii) examined with Minor starch-iodine test. The severity of the diagnosed syndrome was retrospectively evaluated according to the grading score system of Luna-Ortiz. To assess group differences in terms of the extent of dissection in operating sites, we estimated the tumor and histological specimen volumes using the available dimensions. Results: We included Conclusion: Porcine dermal collagen is a safe, practical, and useful means for parotid reconstruction, since it seems to contribute in prevention of Frey's syndrome when increased amount of glandular tissue has to be removed. Additional randomized controlled studies with bigger samples are required to better assess the PDCG use in parotid surgery. |
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| MeSH term(s) | Adenolymphoma/surgery ; Adenoma/surgery ; Adenoma, Pleomorphic ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Chronic Disease ; Collagen/therapeutic use ; Female ; Humans ; Male ; Middle Aged ; Otorhinolaryngologic Surgical Procedures/methods ; Parotid Diseases/surgery ; Parotid Neoplasms/surgery ; Parotitis/surgery ; Postoperative Complications/prevention & control ; Retrospective Studies ; Sialadenitis/surgery ; Sweating, Gustatory/prevention & control ; Teratoma/surgery ; Young Adult | |||||
| Chemical Substances | Permacol ; Collagen (9007-34-5) | |||||
| Language | English | |||||
| Publishing date | 2021-02-06 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 120642-4 | |||||
| ISSN | 1943-572X ; 0003-4894 | |||||
| ISSN (online) | 1943-572X | |||||
| ISSN | 0003-4894 | |||||
| DOI | 10.1177/0003489421990185 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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