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  1. Book ; Online ; Thesis: Bedeutung der Mitogen Aktivierten Proteinkinase (MAPK) P38 bei der Hypertonieentstehung

    Stamer, Stefanie [Verfasser] / Stegbauer, Johannes [Gutachter]

    2023  

    Author's details Stefanie Stamer ; Gutachter: Johannes Stegbauer
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf
    Publishing place Düsseldorf
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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    Inter-library loan at ZB MED

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  2. Book ; Online ; Thesis: Role of Human T Cells in Experimental Hypertension and Hypertensive Kidney Damage

    Rahman, Masudur [Verfasser] / Stegbauer, Johannes [Gutachter] / Lammert, Eckhard [Gutachter]

    2024  

    Author's details Masudur Rahman ; Gutachter: Johannes Stegbauer, Eckhard Lammert
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language English
    Publisher Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf
    Publishing place Düsseldorf
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Book ; Online ; Thesis: In vivo-Modulation von Signalwegen in kardiomyozytenspezifischen AKT-1/2-Doppel-Knockout-Mäusen

    Breuling, Lukas [Verfasser] / Stegbauer, Johannes [Gutachter]

    2022  

    Author's details Lukas Breuling ; Gutachter: Johannes Stegbauer
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf
    Publishing place Düsseldorf
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Book ; Online ; Thesis: Rolle des Mas-Rezeptors auf die Angiotensin-II-induzierte Druckantwort in Nieren von Apolipoprotein-E-defizienten Mäusen

    Ishak, Bassam [Verfasser] / Stegbauer, Johannes [Gutachter] / Temme, Sebastian [Gutachter]

    2023  

    Author's details Bassam Ishak ; Gutachter: Johannes Stegbauer, Sebastian Temme
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf
    Publishing place Düsseldorf
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Book ; Online ; Thesis: Einfluss der transplantierten CD34+- Zellzahl auf die Myelosuppression im Rahmen der Lenalidomid-Erhaltungstherapie nach Hochdosistherapie und autologer Stammzelltransplantation bei Patienten mit Multiplem Myelom

    Klünemann, Jule [Verfasser] / Fenk, Roland [Gutachter] / PD Dr. med. Stegbauer, Johannes [Gutachter]

    2024  

    Author's details Jule Klünemann ; Gutachter: Roland Fenk, Johannes PD Dr. med. Stegbauer
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf
    Publishing place Düsseldorf
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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    Inter-library loan at ZB MED

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  6. Article ; Online: Red blood cell endothelial nitric oxide synthase: A major player in regulating cardiovascular health.

    LoBue, Anthea / Heuser, Sophia K / Lindemann, Marla / Li, Junjie / Rahman, Masudur / Kelm, Malte / Stegbauer, Johannes / Cortese-Krott, Miriam M

    British journal of pharmacology

    2023  

    Abstract: Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non-canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that ...

    Abstract Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non-canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that RBCs can scavenge NO, transport NO metabolites and produce NO in hypoxic conditions, thereby inducing hypoxic vasodilation. RBCs also express endothelial nitric oxide synthase (eNOS). However, the physiological significance of RBC eNOS has been controversial for many years. This review article provides a comprehensive overview of the experimental research on RBC eNOS signalling in vivo. The data show that RBC eNOS signalling modulates intracellular NO production and NO-haem levels, as well as participating in extracellular paracrine NO metabolite signalling, which contributes to regulating peripheral vascular resistance, blood pressure and cardioprotection. Additionally, this article explores the molecular mechanisms of sytemic regulation mediated by RBC eNOS and the implications of RBC eNOS in cardiovascular health and disease.
    Language English
    Publishing date 2023-09-01
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 80081-8
    ISSN 1476-5381 ; 0007-1188
    ISSN (online) 1476-5381
    ISSN 0007-1188
    DOI 10.1111/bph.16230
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uf I Zs.146: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Role of Phosphodiesterase 5 and Cyclic GMP in Hypertension.

    Mergia, Evanthia / Stegbauer, Johannes

    Current hypertension reports

    2016  Volume 18, Issue 5, Page(s) 39

    Abstract: Cyclic GMP (cGMP) is a ubiquitous intracellular second messenger that mediates a wide spectrum of physiologic processes in multiple cell types within the cardiovascular and nervous systems. Synthesis of cGMP occurs either by NO-sensitive guanylyl ... ...

    Abstract Cyclic GMP (cGMP) is a ubiquitous intracellular second messenger that mediates a wide spectrum of physiologic processes in multiple cell types within the cardiovascular and nervous systems. Synthesis of cGMP occurs either by NO-sensitive guanylyl cyclases in response to nitric oxide or by membrane-bound guanylyl cyclases in response to natriuretic peptides and has been shown to regulate blood pressure homeostasis by influencing vascular tone, sympathetic nervous system, and sodium and water handling in the kidney. Several cGMPs degrading phosphodiesterases (PDEs), including PDE1 and PDE5, play an important role in the regulation of cGMP signaling. Recent findings revealed that increased activity of cGMP-hydrolyzing PDEs contribute to the development of hypertension. In this review, we will summarize recent research findings regarding the cGMP/PDE signaling in the vasculature, the central nervous system, and the kidney which are associated with the development and maintenance of hypertension.
    MeSH term(s) Animals ; Cyclic GMP/metabolism ; Cyclic Nucleotide Phosphodiesterases, Type 5/metabolism ; Humans ; Hypertension/metabolism ; Kidney/metabolism ; Nitric Oxide/metabolism ; Renin/metabolism ; Signal Transduction
    Chemical Substances Nitric Oxide (31C4KY9ESH) ; Cyclic Nucleotide Phosphodiesterases, Type 5 (EC 3.1.4.35) ; Renin (EC 3.4.23.15) ; Cyclic GMP (H2D2X058MU)
    Language English
    Publishing date 2016-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2057367-4
    ISSN 1534-3111 ; 1522-6417
    ISSN (online) 1534-3111
    ISSN 1522-6417
    DOI 10.1007/s11906-016-0646-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5522: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Book ; Online ; Thesis: <dc:title>Untersuchung verschiedener Schnelltests zur Bestimmung der korrekten Lage eines Katheters bei der selektiven Nebennierenvenenblutuntersuchung/ Christina Antoniadis ; Gutachter: Holger Willenberg, Johannes Stegbauer</dc:title>

    Antoniadis, Christina [Verfasser] / Willenberg, Holger [Gutachter] / Stegbauer, Johannes [Gutachter]

    2021  

    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf
    Publishing place Düsseldorf
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Book ; Online ; Thesis: Konsistenz in der Messung der linksventrikulären Ejektionsfraktion in der Frühphase nach ST-Hebungs-Myokardinfarkt

    Georgieva, Lilyana [Verfasser] / Bönner, Florian [Gutachter] / PD Dr. med. Stegbauer, Johannes [Gutachter]

    2023  

    Author's details Lilyana Georgieva ; Gutachter: Florian Bönner, Johannes PD Dr. med. Stegbauer
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf
    Publishing place Düsseldorf
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article: Beyond Vessel Diameters: Non-invasive Monitoring of Flow Patterns and Immune Cell Recruitment in Murine Abdominal Aortic Disorders by Multiparametric MRI.

    Temme, Sebastian / Yakoub, Mina / Bouvain, Pascal / Yang, Guang / Schrader, Jürgen / Stegbauer, Johannes / Flögel, Ulrich

    Frontiers in cardiovascular medicine

    2021  Volume 8, Page(s) 750251

    Abstract: The pathophysiology of the initiation and progression of abdominal aortic aneurysms (AAAs) and aortic dissections (AADs) is still unclear. However, there is strong evidence that monocytes and macrophages are of crucial importance in these processes. Here, ...

    Abstract The pathophysiology of the initiation and progression of abdominal aortic aneurysms (AAAs) and aortic dissections (AADs) is still unclear. However, there is strong evidence that monocytes and macrophages are of crucial importance in these processes. Here, we utilized a molecular imaging approach based on background-free
    Language English
    Publishing date 2021-10-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2021.750251
    Database MEDical Literature Analysis and Retrieval System OnLINE

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