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  1. Article ; Online: Major and minor complications in Veress needle (VN) and direct trocar insertion (DTI) for laparoscopic closed-entry techniques: an updated systematic review and meta-analysis.

    Taliento, C / Pontrelli, G / Rondoni, A / Desgro, M / Steinkasserer, M / Scutiero, G / Vizzielli, G / Greco, P

    Langenbeck's archives of surgery

    2023  Volume 408, Issue 1, Page(s) 152

    Abstract: Objective: Direct insertion of the trocar is an alternative method to Veress needle insertion for the creation of pneumoperitoneum. We conducted a systematic review and meta-analysis to compare these two entry closed techniques.: Data source: A ... ...

    Abstract Objective: Direct insertion of the trocar is an alternative method to Veress needle insertion for the creation of pneumoperitoneum. We conducted a systematic review and meta-analysis to compare these two entry closed techniques.
    Data source: A systematic review of the literature was done on PubMed, MEDLINE, Embase, Scopus, and EBSCO.
    Methods: The literature search was constructed until May 01, 2022, around search terms for "Veress," "direct trocar," "needle," "insertion," and "laparoscopic ways of entry." This systematic review was reported according to the PRISMA Statement 2020.
    Results: Sixteen controlled trials (RCTs) and 5 observational studies were included in the systematic review. We found no significant differences in the risk of major complication during the access manoeuvres between DTI and VN: bowel injuries (OR = 0.76, 95% CI: 0.24-2.36, P = 0.63), major vascular injuries (OR = 1.74, 95% CI 0.56-5.38, P = 0.34), port site hernia (OR = 2.41, 95% CI: 0.28-20.71, P = 0.42). DTI has a lower risk of minor complications such as subcutaneous emphysema (OR = 5.19 95% CI: 2.27-11.87, P < 0.0001), extraperitoneal insufflation (OR = 5.93 95% CI: 1.69-20.87, P = 0.006), omental emphysema (OR = 18.41, 95% CI: 7. 01-48.34, P < 0.00001), omental bleeding (OR = 2.32, 95% CI: 1.18-4.55, P = 0.01), and lower number of unsuccessful entry or insufflation attempts (OR = 2.25, 95% CI: 1.05-4.81, P = 0.04). No significant differences were found between the two groups in terms of time required to achieve complete insufflation (MD =  - 15.53, 95% CI: - 91.32 to 60.27, P = 0.69), trocar site bleeding (OR = 0.66, 95% CI, 0.25-1.79, P = 0.42), and trocar site infection (OR = 1.19, 95% CI, 0.34-4.20, P = 0.78).
    Conclusion: There were no statistically significant differences in the risk of major complications during the access manoeuvres between DTI and VN. A lower number of minor complications were observed in DTI compared with those in Veress access.
    MeSH term(s) Humans ; Laparoscopy/adverse effects ; Laparoscopy/methods ; Surgical Instruments/adverse effects ; Pneumoperitoneum, Artificial/adverse effects
    Language English
    Publishing date 2023-04-17
    Publishing country Germany
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 1423681-3
    ISSN 1435-2451 ; 1435-2443
    ISSN (online) 1435-2451
    ISSN 1435-2443
    DOI 10.1007/s00423-023-02891-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Leiomyoma or sarcoma? MRI performance in the differential diagnosis of sonographically suspicious uterine masses.

    Valletta, Riccardo / Corato, Valentina / Lombardo, Fabio / Avesani, Giacomo / Negri, Giovanni / Steinkasserer, Martin / Tagliaferri, Tiziana / Bonatti, Matteo

    European journal of radiology

    2023  Volume 170, Page(s) 111217

    Abstract: Purpose: To assess the diagnostic performance of MRI in distinguishing between leiomyomas and malignant/potentially malignant mesenchymal neoplasms in patients with rapidly enlarging/sonographically suspicious uterine masses.: Methods: IRB-approved ... ...

    Abstract Purpose: To assess the diagnostic performance of MRI in distinguishing between leiomyomas and malignant/potentially malignant mesenchymal neoplasms in patients with rapidly enlarging/sonographically suspicious uterine masses.
    Methods: IRB-approved retrospective study including 88 patients (51 ± 11 years) who underwent MRI for rapidly enlarging/sonographically suspicious uterine mass at our Institution between January 2016 and December 2021, followed by surgery or >12 months follow-up. Qualitative image analysis was independently performed by 2 radiologists and included lesion's margins (sharp/irregular), architecture (homogeneous/inhomogeneous), presence of endometrial infiltration (yes/no), necrotic areas (yes/no), hemorrhagic areas (yes/no), predominant signal intensity on T1-WI, T2-WI, CE T1-WI, DWI, and ADC map. The same radiologists performed quantitative image analysis in consensus, which included lesion's maximum diameter, lesion/myometrium signal intensity ratio on T2-WI and CE T1-weighted images, lesion/endometrium signal intensity ratio on DWI and ADC map and necrosis percentage. Lesions were classified as benign or malignant. Imaging findings were compared with pathology and/or follow-up.
    Results: After surgery (52/88 patients) or follow-up (36/88 patients, 33 ± 20 months), 83/88 (94.3%) lesions were classified as benign and 5/88 (5.7%) as malignant/potentially malignant. Presence of necrotic areas, high necrosis percentage, hyperintensity on DWI and high lesion/endometrium DWI signal intensity ratio were significantly associated with malignant/potentially malignant lesions (p = 0.027, 0.002, 0.008 and 0.015, respectively). The two readers identified malignant/potentially malignant lesions with 95.5% accuracy, 80.0% sensitivity, 96.4% specificity, 57.1 % PPV, 93.3% NPV.
    Conclusion: MRI has high accuracy in identifying malignant/potentially malignant myometrial masses. In everyday practice, however, MRI positive predictive value is relatively low given the low pre-test malignancy probability.
    MeSH term(s) Female ; Humans ; Uterine Neoplasms/diagnostic imaging ; Uterine Neoplasms/pathology ; Retrospective Studies ; Diagnosis, Differential ; Sensitivity and Specificity ; Leiomyoma/diagnostic imaging ; Leiomyoma/pathology ; Magnetic Resonance Imaging/methods ; Sarcoma ; Necrosis ; Diffusion Magnetic Resonance Imaging/methods
    Language English
    Publishing date 2023-11-25
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 138815-0
    ISSN 1872-7727 ; 0720-048X
    ISSN (online) 1872-7727
    ISSN 0720-048X
    DOI 10.1016/j.ejrad.2023.111217
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Seltene Raumforderung der Brust.

    Ruiu, A / Stuppner, S / Bertelli, G / Armatura, G / Luethy, M / Damiani, D / Cagini, A / Steinkasserer, M / Lusso, M R / Ferro, F

    Der Radiologe

    2021  Volume 61, Issue 11, Page(s) 1020–1023

    Title translation Rare mass in the breast.
    MeSH term(s) Breast/diagnostic imaging ; Breast Neoplasms/diagnostic imaging ; Female ; Humans
    Language German
    Publishing date 2021-07-21
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 505520-9
    ISSN 1432-2102 ; 0033-832X
    ISSN (online) 1432-2102
    ISSN 0033-832X
    DOI 10.1007/s00117-021-00888-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Non-human papilloma virus associated adenocarcinomas of the cervix uteri. Cytologic features and diagnostic agreement using whole slide digital cytology imaging.

    Negri, Giovanni / Macciocu, Elena / Cepurnaite, Rima / Kasal, Armin / Troncone, Giancarlo / Steinkasserer, Martin / Vittadello, Fabio

    Diagnostic cytopathology

    2020  Volume 49, Issue 2, Page(s) 316–321

    Abstract: Background: Non-Human Papilloma Virus associated adenocarcinomas (NHPVAs) are uncommon tumors of the cervix uteri which often show a deceptive morphology. Therefore, their diagnostic assessment may be challenging. Slide digital cytology imaging may be ... ...

    Abstract Background: Non-Human Papilloma Virus associated adenocarcinomas (NHPVAs) are uncommon tumors of the cervix uteri which often show a deceptive morphology. Therefore, their diagnostic assessment may be challenging. Slide digital cytology imaging may be an useful tool to improve cytological diagnostic accuracy. However, this novel technology has not been applied to NHPVAs associated cytologies yet.
    Methods: The study included 31 whole slide digital cytology cases from 10 women with a proven histological diagnosis of NHPVA. As a control group, three further digital slides, from two women with a histological diagnosis of squamous intraepithelial lesion (SIL), were included. The digitally scanned cytological slides were revised to assess the concordance rate among three observers and to find out the most relevant NHPVA cytological criteria.
    Results: Overall diagnostic agreement between observers was 67.60% (K = 0.50; P < 0.0001). At the consensus diagnosis 34 cases were re-classified as at least suspicious for glandular lesion (n = 24), SIL (n = 2) and negative (n = 8). The most relevant cytologic features for atypical glandular cells or adenocarcinoma at consensus were evident nucleoli, nuclear overlapping and atypical enlarged nuclei.
    Conclusions: The diagnosis of NHPVA in digital cytology is feasible using criteria which are also used in conventional microscopy. Our study shows a moderate agreement for the cytological diagnosis of NHPVAs using whole slide digital cytology approach. These results are discussed taking into account the most relevant differential diagnostic issues.
    MeSH term(s) Adenocarcinoma/diagnosis ; Adenocarcinoma/pathology ; Adenocarcinoma/virology ; Cervix Uteri/pathology ; Cervix Uteri/virology ; Cytodiagnosis/methods ; Cytological Techniques/methods ; Female ; Humans ; Image Processing, Computer-Assisted/methods ; Microscopy/methods ; Uterine Cervical Neoplasms/diagnosis ; Uterine Cervical Neoplasms/pathology ; Uterine Cervical Neoplasms/virology ; Vaginal Smears/methods
    Language English
    Publishing date 2020-10-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632710-2
    ISSN 1097-0339 ; 8755-1039
    ISSN (online) 1097-0339
    ISSN 8755-1039
    DOI 10.1002/dc.24652
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Endometriosis in the north Italian province of South Tyrol.

    Steinkasserer, Martin / Engl, Bruno

    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology

    2009  Volume 25, Issue 11, Page(s) 748–750

    Abstract: Here, we report regarding the health status and medical support for patients suffering from endometrioisis in South Tyrol, which is a politically autonomous province in the north of Italy containing three different ethnic groups. The health service is ... ...

    Abstract Here, we report regarding the health status and medical support for patients suffering from endometrioisis in South Tyrol, which is a politically autonomous province in the north of Italy containing three different ethnic groups. The health service is administered largely by the autonomous regional government. Because of the establishment of a centre for reproductive medicine and the introduction of laparoscopy as a prime surgery method, the gynaecological department of the hospital in Bruneck developed into a reference centre for diagnosis and surgical treatment for endometriosis. The planned future social, health care and insurance developments on local and national level regarding this illness will be discussed.
    MeSH term(s) Endometriosis/diagnosis ; Endometriosis/epidemiology ; Endometriosis/physiopathology ; Endometriosis/surgery ; Female ; Health Policy ; Health Status ; Humans ; Incidence ; Italy/epidemiology ; National Health Programs
    Language English
    Publishing date 2009-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 639237-4
    ISSN 1473-0766 ; 0951-3590
    ISSN (online) 1473-0766
    ISSN 0951-3590
    DOI 10.3109/09513590903230408
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Laparoscopic Radiofrequency Thermal Ablation for Uterine Adenomyosis.

    Scarperi, Stefano / Pontrelli, Giovanni / Campana, Colette / Steinkasserer, Martin / Ercoli, Alfredo / Minelli, Luca / Bergamini, Valentino / Ceccaroni, Marcello

    JSLS : Journal of the Society of Laparoendoscopic Surgeons

    2015  Volume 19, Issue 4

    Abstract: Background and objectives: Symptomatic uterine adenomyosis, unresponsive to medical therapy, is a challenging condition for patients who desire to preserve their uterus. This study was an evaluation of the feasibility and efficacy of laparoscopic ... ...

    Abstract Background and objectives: Symptomatic uterine adenomyosis, unresponsive to medical therapy, is a challenging condition for patients who desire to preserve their uterus. This study was an evaluation of the feasibility and efficacy of laparoscopic radiofrequency thermal ablation of symptomatic nodular uterine adenomyosis.
    Methods: Fifteen women with symptomatic nodular adenomyosis, who had no plans for pregnancy but declined hysterectomy, underwent radiofrequency thermal ablation. Ultrasonography was performed at baseline and at postoperative follow-ups at 3, 6, 9, and 12 months. The impact of uterine adenomyosis-related symptoms was assessed according to the visual analog scale.
    Results: The median number of nodular lesions treated per patient was 1 (range, 1-2). The median baseline volume of the adenomyosis area was 60 cm(3) (range, 18-128). The median reduction in volume was 32, 49.4, 59.6, and 65.4% at 3, 6, 9, and 12 months, respectively. A significant progressive improvement in the symptoms score was observed at the 4 follow-ups.
    Conclusion: In this study, laparoscopic radiofrequency thermal ablation reduced uterine adenomyosis-related symptoms and volume, with significant relief of symptoms.
    MeSH term(s) Adenomyosis/diagnostic imaging ; Adenomyosis/surgery ; Adult ; Catheter Ablation ; Feasibility Studies ; Female ; Follow-Up Studies ; Humans ; Laparoscopy ; Middle Aged ; Ultrasonography ; Visual Analog Scale
    Language English
    Publishing date 2015-11-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2011211-7
    ISSN 1938-3797 ; 1086-8089
    ISSN (online) 1938-3797
    ISSN 1086-8089
    DOI 10.4293/JSLS.2015.00071
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Distribution of endometriotic lesions in endometriosis stage IV supports the menstrual reflux theory and requires specific preoperative assessment and therapy.

    Scioscia, Marco / Bruni, Francesco / Ceccaroni, Marcello / Steinkasserer, Martin / Stepniewska, Anna / Minelli, Luca

    Acta obstetricia et gynecologica Scandinavica

    2011  Volume 90, Issue 2, Page(s) 136–139

    Abstract: A detailed picture of the prevalence and distribution of abdomino-pelvic endometriosis in more that 1,500 cases of endometriosis stage IV is presented. A great prevalence of endometriotic localizations in the posterior pelvic compartment compared to the ... ...

    Abstract A detailed picture of the prevalence and distribution of abdomino-pelvic endometriosis in more that 1,500 cases of endometriosis stage IV is presented. A great prevalence of endometriotic localizations in the posterior pelvic compartment compared to the other quadrants with more frequently observed lesions on the left part of the pelvis supports the menstrual reflux theory. The extent of anatomical sites suggests the opportunity to plan a proper preoperative instrumental study for patients with clinical suspect of severe endometriosis possibly to set a multidisciplinary clinical or surgical management.
    MeSH term(s) Endometriosis/pathology ; Endometriosis/therapy ; Female ; Humans ; Menstruation Disturbances/etiology ; Menstruation Disturbances/pathology ; Menstruation Disturbances/therapy
    Language English
    Publishing date 2011-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80019-3
    ISSN 1600-0412 ; 0001-6349
    ISSN (online) 1600-0412
    ISSN 0001-6349
    DOI 10.1111/j.1600-0412.2010.01008.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Successful laparoscopic management of adnexal torsion during week 15 of a single pregnancy.

    Pezzuto, Antonio / Steinkasserer, Martin / Tricolore, Carlo / Ferrari, Bruno / Nardelli, Giovanni Battista / Minelli, Luca

    Journal of minimally invasive gynecology

    2010  Volume 17, Issue 6, Page(s) 686

    MeSH term(s) Adnexal Diseases/surgery ; Adult ; Female ; Gestational Age ; Humans ; Laparoscopy ; Pregnancy ; Pregnancy Complications ; Torsion Abnormality/surgery
    Language English
    Publishing date 2010-11
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2186934-0
    ISSN 1553-4669 ; 1553-4650
    ISSN (online) 1553-4669
    ISSN 1553-4650
    DOI 10.1016/j.jmig.2009.09.020
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  9. Article ; Online: Patient with pelvic pains: retroperitoneal fibrosis or pelvic endometriosis? A case report and review of literature.

    Pezzuto, Antonio / Pomini, Paola / Steinkasserer, Martin / Nardelli, Giovanni Battista / Minelli, Luca

    Fertility and sterility

    2009  Volume 92, Issue 4, Page(s) 1497.e9–1497.e12

    Abstract: Objective: To describe how a hydronephrosis can lead to a difficult differential diagnosis between endometriosis and retroperitoneal fibrosis.: Design: Case report.: Setting: Department of Obstetrics and Gynecology, Sacro Cuore Don Calabria ... ...

    Abstract Objective: To describe how a hydronephrosis can lead to a difficult differential diagnosis between endometriosis and retroperitoneal fibrosis.
    Design: Case report.
    Setting: Department of Obstetrics and Gynecology, Sacro Cuore Don Calabria General Hospital, Negrar, Verona, Italy.
    Patient(s): The history of a 34-year-old woman revealed the appearance of hydroureteronephrosis on the right side at the 35th week of pregnancy. She had an magnetic resonance imaging scan and was diagnosed with a spread retroperitoneal fibrosis. After 2 months, the patient reported the occurrence of pelvic pain, dyspareunia and dysmenorrhea. She was treated with corticosteroids and tamoxifen with no results.
    Intervention(s): Laparoscopic surgery. A complete retroperitoneal extirpation was done of an endometriotic nodule of the right broad ligament, near the right ureter (without stenosis).
    Main outcome measure(s): Reduction of pelvic pain.
    Result(s): She noticed an important decrease of pain.
    Conclusion(s): The cause of hydronephrosis could be a physiologic hydroureteronephrosis, which is the most common cause of dilatation of the urinary tract in pregnancy. The pain symptoms of the patients seemed to be linked to endometriosis and not to retroperitoneal fibrosis. Magnetic resonance imaging sometimes does not enable a correct diagnosis between these two pathologies. Fertile women with suspected fibrosis should undergo a diagnostic laparoscopy by an expert surgeon in retroperitoneal surgery.
    MeSH term(s) Adnexal Diseases/complications ; Adnexal Diseases/diagnosis ; Adult ; Diagnosis, Differential ; Endometriosis/complications ; Endometriosis/diagnosis ; Female ; Humans ; Hydronephrosis/complications ; Hydronephrosis/diagnosis ; Pelvic Pain/diagnosis ; Pelvic Pain/etiology ; Pelvis/pathology ; Pregnancy ; Pregnancy Complications/diagnosis ; Pregnancy Complications/etiology ; Retroperitoneal Fibrosis/complications ; Retroperitoneal Fibrosis/diagnosis
    Language English
    Publishing date 2009-08-22
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 80133-1
    ISSN 1556-5653 ; 0015-0282
    ISSN (online) 1556-5653
    ISSN 0015-0282
    DOI 10.1016/j.fertnstert.2009.07.982
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  10. Article: Successful laparoscopic management of spontaneous hemoperitoneum at 15 weeks of pregnancy: case report and review of literature.

    Pezzuto, Antonio / Pomini, Paola / Steinkasserer, Martin / Nardelli, Giovanni Battista / Minelli, Luca

    Journal of minimally invasive gynecology

    2009  Volume 16, Issue 6, Page(s) 792–794

    Abstract: We present a case report of laparoscopic management of a spontaneous hemoperitoneum in the second trimester of pregnancy. The patient was a 40-year-old woman at 15 weeks of gestation. At laparoscopic surgery, the hemoperitoneum was evacuated, and the ... ...

    Abstract We present a case report of laparoscopic management of a spontaneous hemoperitoneum in the second trimester of pregnancy. The patient was a 40-year-old woman at 15 weeks of gestation. At laparoscopic surgery, the hemoperitoneum was evacuated, and the right-sided uterine vessels were closed with diathermocoagulation. Every pregnant woman with severe abdominal pain, vomiting, and imminent hypovolemic shock should be carefully evaluated. After ruling out the most prevalent causes of hemoperitoneum, idiopathic spontaneous hemoperitoneum should be considered. Rapid diagnosis and aggressive fluid replacement together with prompt surgical intervention may be the only chance for a favorable outcome for both mother and child in the presence of such a rare complication. Moreover, in early stages of pregnancy, the laparoscopic approach should be considered but only in the hands of experienced laparoscopic surgeons.
    MeSH term(s) Adult ; Electrocoagulation ; Female ; Hemoperitoneum/complications ; Hemoperitoneum/surgery ; Humans ; Laparoscopy/methods ; Pregnancy ; Pregnancy Complications, Cardiovascular/surgery ; Pregnancy Trimester, Second
    Language English
    Publishing date 2009-11
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 2186934-0
    ISSN 1553-4669 ; 1553-4650
    ISSN (online) 1553-4669
    ISSN 1553-4650
    DOI 10.1016/j.jmig.2009.08.007
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